Recently, non-invasive, real-time and multi-point measurement of neural activities has become possible by using a multi-electrode array (MEA). Another method for multi-point measurement is the fluorescent imaging tech...Recently, non-invasive, real-time and multi-point measurement of neural activities has become possible by using a multi-electrode array (MEA). Another method for multi-point measurement is the fluorescent imaging technique using voltage indicator dyes or calcium indicator dyes. Especially, calcium imaging using fluorescent calcium indicator dyes is often more useful, because they exhibit larger changes in the fluorescence intensity than voltage indicator dyes and their fluorescence changes can be detect easily. Additionally, calcium signals play key roles in the brain function, such as the long-term potentiation (LTP) in the hippocampus, and calcium imaging can be a powerful tool to elucidate the brain function. In this study, we constructed a measurement apparatus combining the MEA system and laser confocal calcium imaging and simultaneously measured electric signals and calcium signals in acute mouse hippocampal slices. The obtained results showed the availability of the present method.展开更多
This paper is devoted to the development of new technology called laser parallel thermocracking that applicable for brittle nonmetallic materials such as glass, sapphire, silicon etc. The mathematical model of laser p...This paper is devoted to the development of new technology called laser parallel thermocracking that applicable for brittle nonmetallic materials such as glass, sapphire, silicon etc. The mathematical model of laser parallel thermocracking process is introduced. Results of experimental researches are shown in order that define the interrelation between the basic parameters of laser parallel thermocracking process.展开更多
Direct slicing from GAD models to generate sectional contours of the part to be sintered for Selective Laser Sintering （SLS） may overcome inherent disadvantages of using a Stereo Lithography （STL） format. In this ...Direct slicing from GAD models to generate sectional contours of the part to be sintered for Selective Laser Sintering （SLS） may overcome inherent disadvantages of using a Stereo Lithography （STL） format. In this paper, a direct slicing procedure is proposed for Selective Laser Sintering based on material performance and process parameters. Slicing thickness depends on the 3 D geometric model, material performance and process parameters. The relationship among material performance, process parameters and the largest slicing thickness is established using analysis of a sintering temperature field. A dynamic linked library is developed to realize direct slicing from a CAD model.展开更多
文摘Recently, non-invasive, real-time and multi-point measurement of neural activities has become possible by using a multi-electrode array (MEA). Another method for multi-point measurement is the fluorescent imaging technique using voltage indicator dyes or calcium indicator dyes. Especially, calcium imaging using fluorescent calcium indicator dyes is often more useful, because they exhibit larger changes in the fluorescence intensity than voltage indicator dyes and their fluorescence changes can be detect easily. Additionally, calcium signals play key roles in the brain function, such as the long-term potentiation (LTP) in the hippocampus, and calcium imaging can be a powerful tool to elucidate the brain function. In this study, we constructed a measurement apparatus combining the MEA system and laser confocal calcium imaging and simultaneously measured electric signals and calcium signals in acute mouse hippocampal slices. The obtained results showed the availability of the present method.
文摘This paper is devoted to the development of new technology called laser parallel thermocracking that applicable for brittle nonmetallic materials such as glass, sapphire, silicon etc. The mathematical model of laser parallel thermocracking process is introduced. Results of experimental researches are shown in order that define the interrelation between the basic parameters of laser parallel thermocracking process.
文摘Direct slicing from GAD models to generate sectional contours of the part to be sintered for Selective Laser Sintering （SLS） may overcome inherent disadvantages of using a Stereo Lithography （STL） format. In this paper, a direct slicing procedure is proposed for Selective Laser Sintering based on material performance and process parameters. Slicing thickness depends on the 3 D geometric model, material performance and process parameters. The relationship among material performance, process parameters and the largest slicing thickness is established using analysis of a sintering temperature field. A dynamic linked library is developed to realize direct slicing from a CAD model.
