Background Detecting small breast tumors is difficult for conventional ultrasound. The goal of this study was to assess the value of ultrasound elastography in characterizing small breast tumors and to compare its sen...Background Detecting small breast tumors is difficult for conventional ultrasound. The goal of this study was to assess the value of ultrasound elastography in characterizing small breast tumors and to compare its sensitivity, specificity and accuracy with conventional ultrasound. Methods A total of 308 breast tumors less than 2 cm in size from 283 in-hospital patients examined with both conventional ultrasound and ultrasound elastography were retrospectively analyzed. The results were compared to surgical pathology. Results There were 104 malignant and 204 benign lesions. The sensitivities of sonography and sonoelastography were similar （P 〈0.05）, and the sensitivity of the two modalities combined improved remarkably to 97.1%. The mean elastic score of malignant and benign tumors less than 2 cm were 3.76±1.01 and 1.73±0.99, respectively （P 〈0.05）, and the mean elastic score of the false-negative lesions on conventional ultrasound was 3.61±1.14. Conclusions Ultrasound elastography in combination with conventional ultrasound can improve the sensitivity for detecting small breast tumors. It is also valuable in detecting small malignant tumors which are difficult to diagnose with conventional ultrasound. Ultrasound elastography can be a useful adjunct to conventional ultrasound in diagnosing small breast tumors.展开更多
Synchronous tumors are an uncommon finding. We present a case of metastatic carcinoma of right breast and a left lung adenocarcinoma in a patient with previous history of left breast cancer diagnosed twelve years ago....Synchronous tumors are an uncommon finding. We present a case of metastatic carcinoma of right breast and a left lung adenocarcinoma in a patient with previous history of left breast cancer diagnosed twelve years ago. She was then treated with chemotherapy, radiotherapy and hormone therapy. Initially, the greatest diagnostic challenge was which of them had spread or if both had. Or even if, any of these lesions resulted from the primary left breast cancer. So, specimens of different metastatic lesions were crucial to answer this query and to decide the best therapeutic approach. Sequencing the treatment options in managing two synchronous secondary malignancies, where one of them is metastatic and the other one is potentially curable, was a demanding clinical decision.展开更多
[目的]探讨156例ⅠA期乳腺癌患者的临床病理特征、中医证型、治疗与预后的关系。[方法]收集2004年1月—2009年12月天津医科大学肿瘤医院收治的156例早期乳腺癌(T_1N_0M_0,ⅠA期)的临床病理资料进行回顾性分析。[结果]患者病理类型以浸...[目的]探讨156例ⅠA期乳腺癌患者的临床病理特征、中医证型、治疗与预后的关系。[方法]收集2004年1月—2009年12月天津医科大学肿瘤医院收治的156例早期乳腺癌(T_1N_0M_0,ⅠA期)的临床病理资料进行回顾性分析。[结果]患者病理类型以浸润性导管癌为主;中医辨证临床可分为肝气郁结证、冲任失调证、燥毒蕴结证及气血双亏兼邪毒内陷证4型,以肝气郁结证为主;原发肿瘤大小以T1c居多;组织学分级以Ⅱ级及Ⅲ级为主。5 a PFS为93.3%,5 a OS为99.1%。单因素分析结果显示,组织学分级、Ki-67表达及淋巴脉管侵犯与患者的PFS相关;多因素分析显示,组织学分级及Ki-67表达情况是影响ⅠA期(T_1N_0M_0)乳腺癌患者PFS的独立预后因素。[结论]ⅠA期(T_1N_0M_0)乳腺癌患者虽然总体预后较好,但某些亚组患者预后较差,存在明显的复发转移风险。展开更多
目的分析乳腺小肿瘤二维及彩色多普勒超声显像特征,以提高诊断乳腺肿瘤的正确率。方法采用彩色多普勒超声对118例乳腺肿瘤进行检查,分析超声图像特征,并与病理学结果进行比较。结果二维彩超诊断乳腺小肿瘤准确率为86.44%(102/118)。乳...目的分析乳腺小肿瘤二维及彩色多普勒超声显像特征,以提高诊断乳腺肿瘤的正确率。方法采用彩色多普勒超声对118例乳腺肿瘤进行检查,分析超声图像特征,并与病理学结果进行比较。结果二维彩超诊断乳腺小肿瘤准确率为86.44%(102/118)。乳腺癌造影剂始增时间、达峰时间明显短于良性肿瘤组(8.45±0.21 vs 10.42±3.22,15.42±0.59 vs 20.61±4.53)s,明显减退时间明显长于良性肿瘤组(64.25±15.68 vs 53.03±13.52)s,峰值强度明显高于良性肿瘤组(51.59±3.29 vs 11.02±5.72)d B。结论乳腺小肿瘤二维及彩色多普勒超声表现具有特征性,有助于提高乳腺小肿瘤的鉴别诊断。展开更多
文摘Background Detecting small breast tumors is difficult for conventional ultrasound. The goal of this study was to assess the value of ultrasound elastography in characterizing small breast tumors and to compare its sensitivity, specificity and accuracy with conventional ultrasound. Methods A total of 308 breast tumors less than 2 cm in size from 283 in-hospital patients examined with both conventional ultrasound and ultrasound elastography were retrospectively analyzed. The results were compared to surgical pathology. Results There were 104 malignant and 204 benign lesions. The sensitivities of sonography and sonoelastography were similar （P 〈0.05）, and the sensitivity of the two modalities combined improved remarkably to 97.1%. The mean elastic score of malignant and benign tumors less than 2 cm were 3.76±1.01 and 1.73±0.99, respectively （P 〈0.05）, and the mean elastic score of the false-negative lesions on conventional ultrasound was 3.61±1.14. Conclusions Ultrasound elastography in combination with conventional ultrasound can improve the sensitivity for detecting small breast tumors. It is also valuable in detecting small malignant tumors which are difficult to diagnose with conventional ultrasound. Ultrasound elastography can be a useful adjunct to conventional ultrasound in diagnosing small breast tumors.
文摘Synchronous tumors are an uncommon finding. We present a case of metastatic carcinoma of right breast and a left lung adenocarcinoma in a patient with previous history of left breast cancer diagnosed twelve years ago. She was then treated with chemotherapy, radiotherapy and hormone therapy. Initially, the greatest diagnostic challenge was which of them had spread or if both had. Or even if, any of these lesions resulted from the primary left breast cancer. So, specimens of different metastatic lesions were crucial to answer this query and to decide the best therapeutic approach. Sequencing the treatment options in managing two synchronous secondary malignancies, where one of them is metastatic and the other one is potentially curable, was a demanding clinical decision.
文摘[目的]探讨156例ⅠA期乳腺癌患者的临床病理特征、中医证型、治疗与预后的关系。[方法]收集2004年1月—2009年12月天津医科大学肿瘤医院收治的156例早期乳腺癌(T_1N_0M_0,ⅠA期)的临床病理资料进行回顾性分析。[结果]患者病理类型以浸润性导管癌为主;中医辨证临床可分为肝气郁结证、冲任失调证、燥毒蕴结证及气血双亏兼邪毒内陷证4型,以肝气郁结证为主;原发肿瘤大小以T1c居多;组织学分级以Ⅱ级及Ⅲ级为主。5 a PFS为93.3%,5 a OS为99.1%。单因素分析结果显示,组织学分级、Ki-67表达及淋巴脉管侵犯与患者的PFS相关;多因素分析显示,组织学分级及Ki-67表达情况是影响ⅠA期(T_1N_0M_0)乳腺癌患者PFS的独立预后因素。[结论]ⅠA期(T_1N_0M_0)乳腺癌患者虽然总体预后较好,但某些亚组患者预后较差,存在明显的复发转移风险。
文摘目的分析乳腺小肿瘤二维及彩色多普勒超声显像特征,以提高诊断乳腺肿瘤的正确率。方法采用彩色多普勒超声对118例乳腺肿瘤进行检查,分析超声图像特征,并与病理学结果进行比较。结果二维彩超诊断乳腺小肿瘤准确率为86.44%(102/118)。乳腺癌造影剂始增时间、达峰时间明显短于良性肿瘤组(8.45±0.21 vs 10.42±3.22,15.42±0.59 vs 20.61±4.53)s,明显减退时间明显长于良性肿瘤组(64.25±15.68 vs 53.03±13.52)s,峰值强度明显高于良性肿瘤组(51.59±3.29 vs 11.02±5.72)d B。结论乳腺小肿瘤二维及彩色多普勒超声表现具有特征性,有助于提高乳腺小肿瘤的鉴别诊断。
