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Etiology, Prevalence, and Management of Oral and Maxillofacial Soft Tissue Injuries in Children at the Komfo Anokye Teaching Hospital, Kumasi-Ghana
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作者 Robert Nii Lamy Larmie Ama Agyeibea Amuasi +2 位作者 Solomon Obiri-Yeboah Alexander Oti Acheampong Peter Donkor 《Open Journal of Stomatology》 2023年第8期243-255,共13页
Background: Maxillofacial injury may vary from simple soft tissue lacerations to complex fractures of the orofacial region. Soft tissue injuries, whether isolated or in combination with other injuries, form part of th... Background: Maxillofacial injury may vary from simple soft tissue lacerations to complex fractures of the orofacial region. Soft tissue injuries, whether isolated or in combination with other injuries, form part of the frequent traumatic craniofacial injuries seen at the emergency department. The force of impact and the injury type is directly related to the severity of the injury sustained. This study aimed to analyze the etiological factors, prevalence, and management of oral and maxillofacial soft tissue injuries at the Komfo Anokye Teaching Hospital. Methods: This was a prospective study that involved children presenting with oral and maxillofacial injuries at the Accident and Emergency Department and the Oral and Maxillofacial Surgery unit of the Komfo Anokye Teaching Hospital in Kumasi between the period of April to October 2020 (6 months). Patient selection was by convenience sampling targeting all children with injuries who met the inclusion criteria. Inclusion criteria were children below the age of 18 years whose parents or caregivers consent to participation. Children with maxillofacial injuries as a result of burns were excluded from the study. Results: During the study period a total of 134 children were reviewed with oral and maxillofacial injuries at KATH. Of these, 107 (78.9%) were recorded cases of orofacial soft tissue injuries. There were 63 (58.9%) males and 44 (41.1%) females and the male-to-female ratio was 1.5:1. The age range of patients studied was 8 months – 17 years, with mean age ± SD being 9.5 ± 5.3 years. Road Traffic Crash (50.5%) was the most common etiology of which Motor cycle crash constituted 24.3% and Pedestrian knockdown was 19.6%. Falls (42.1%) were the next most common etiology. The lips (19.8%) and the forehead (18.5%) were the most frequently injured sites on the face whiles the tongue (3.3%) had the most injuries intraorally. Laceration (45.7%) was the most frequent injury reviewed, followed by abrasions (35.8%). Most of the soft tissue injuries underwent primary closure (56.3%). A complication rate of 21.2% was recorded in this study and hypertrophic scarring (11.3%) was the most observed. 展开更多
关键词 LACERATION soft tissue Injury ETIOLOGY Maxillofacial Injury PREVALENCE MANAGEMENT CHILDREN
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Is it time to put traditional cold therapy in rehabilitation of soft-tissue injuries out to pasture? 被引量:8
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作者 Zi-Ru Wang Guo-Xin Ni 《World Journal of Clinical Cases》 SCIE 2021年第17期4116-4122,共7页
Cold therapy has been used regularly as an immediate treatment to induce analgesia following acute soft-tissue injuries,however,a prolonged ice application has proved to delay the start of the healing and lengthen the... Cold therapy has been used regularly as an immediate treatment to induce analgesia following acute soft-tissue injuries,however,a prolonged ice application has proved to delay the start of the healing and lengthen the recovery process.Hyperbaric gaseous cryotherapy,also known as neurocryostimulation,has shown the ability to overcome most of the limitations of traditional cold therapy,and meanwhile promotes the analgesic and anti-inflammatory effects well,but the current existing studies have shown conflicting results on its effects.Traditional cold therapy still has beneficial effect especially when injuries are severe and swelling is the limiting factor for recovery after soft-tissue injuries,and therefore no need to be entirely put out to pasture in the rehabilitation practice.Strong randomized controlled trials with good methodological quality are still needed in the future to evaluate the effects of different cryotherapy modalities. 展开更多
关键词 CRYOTHERAPY Hyperbaric gaseous cryotherapy Neurocryostimulation Cold therapy soft tissue injury
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Terrorist attacks in the largest metropolitan city of Pakistan: Profile of soft tissue and skeletal injuries from a single trauma center
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作者 Muhammad Shahid Khan Shahan Waheed +3 位作者 Arif Ali Narjis Mumtaz Asher Feroze Shahryar Noordin 《World Journal of Emergency Medicine》 CAS 2015年第3期217-220,共4页
BACKGROUND: Pakistan has been hugely struck with massive bomb explosions(car and suicide bombs) resulting in multiple casualties in the past few years. The aim of this study is to present the patterns of skeletal and ... BACKGROUND: Pakistan has been hugely struck with massive bomb explosions(car and suicide bombs) resulting in multiple casualties in the past few years. The aim of this study is to present the patterns of skeletal and soft tissue injuries and to review the outcome of the victims who presented to our hospital.METHODS: This is a retrospective chart review from January 2008 to December 2012. The medical record numbers of patients were obtained from the hospital Health Information and Management Sciences(HIMS) as per the ICD-9 coding.RESULTS: During the study period, more than 100 suicide and implanted bomb blast attacks took place in the public proceedings, government offices, residential areas and other places of the city. Altogether 262 patients were enrolled in the study. The mean age of the patients was 31±14 years. The shrapnel inflicted wounds were present on to the upper limb in 24 patients and the lower limb in 50.CONCLUSION: Long bone fractures were the most common skeletal injuries. The fractures were complicated by penetrating fragments and nails which result in post operative infections and prolonged hospital stay. 展开更多
关键词 soft tissue injuries Pakistan
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Therapeutic Effect and Mechanism of Jipei Dilong Ointment on Acute Soft Tissue Injury in Rats
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作者 Yihui CHAI Haotian WANG +6 位作者 Shiyun YE Lailai LI Baoying HUA Jinghua RUAN Xiang PU Liyan ZHANG Sibu MA 《Agricultural Biotechnology》 CAS 2023年第5期35-42,共8页
[Objectives]This study was conducted to observe the therapeutic effect of Jipei Dilong Ointment on rats with acute soft tissue injury caused by heavy objects and to explore its action mechanism.[Methods]Thirty six rat... [Objectives]This study was conducted to observe the therapeutic effect of Jipei Dilong Ointment on rats with acute soft tissue injury caused by heavy objects and to explore its action mechanism.[Methods]Thirty six rats were randomly divided into six groups(control group,model group,high-dose Jipei Dilong Ointment group(JP-H),medium-dose Jipei Dilong Ointment group(JP-M),low-dose Jipei Dilong Ointment group(JP-L)and diclofenac group).Except for the Control group,other groups were subjected to modeling of acute soft tissue injury by the weight impact method.All administration was performed once a day for nine consecutive days.The local appearance score and activity disorder score were determined after soft tissue injury in rats.HE staining was used to detect the pathological changes of injured soft tissues in rats.RT-PCR was used to detect the relative mRNA expressions of Bax,Bcl-2,MMP-9 and TIMP-1 in injured soft tissues of rats.Western Blot was used to detect the protein expressions of MMP-9,TIMP-1,TLR4,MyD88 and NF-κB p65 in injured soft tissues of rats.Results were statistically analyzed.[Results]Compared with the model group,Jipei Dilong Ointment could significantly improve the appearance symptoms such as swelling and ecchymosis in the injured area and the movement function of the affected limb(P<0.05).It could also improve the infiltration of inflammatory cells and widening of the intermuscular space caused by injury.Among them,the JP-H group and the diclofenac group had more significant curative effects.After 9 d of administration,each administration group could significantly up-regulate the ratio of Bcl-2/Bax mRNA expression level(P<0.05 or P<0.01),and the ratio of MMP-9/TIMP-1 mRNA expression level showed a downward trend(P>0.05).The expression level of NF-κB p65 protein in each administration group was significantly decreased(P<0.01).The protein expression levels of TLR4 and MyD88 and the ratio of MMP-9/TIMP-1 protein expression level in each administration group decreased to varying degrees.Among them,the JP-H group and diclofenac group significantly decreased(P<0.05).[Conclusions]Jipei Dilong Ointment has the functions of relieving pain,swelling and inflammation.It could improve the local appearance,functional activity and tissue morphology of affected limbs in rats,and has a therapeutic effect on acute soft tissue injury in rats.Its mechanism of action might be related to the inhibition of TLR4/MyD88/NF-κB p65 signaling pathway and the regulation of Bcl-2/Bax and MMP-9/TIMP-1 balance. 展开更多
关键词 Jipei Dilong Ointment Acute soft tissue injury NF-κB p65 TLR4 MYD88
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Advantages of Ilizarov External Fixation in an Elderly Patient with Pilon Fracture with Severe Soft Tissue Injury and Severe Osteoporosis: A Case Report 被引量:3
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作者 Koji Nozaka Naohisa Miyakoshi +5 位作者 Hidetomo Saito Shuichi Chida Hiroyuki Tsuchie Yusuke Yuasa Motoki Mita Yoichi Shimada 《Open Journal of Orthopedics》 2019年第1期14-22,共9页
Introduction: Pilon fracture in elderly individuals is characterized by senile skin atrophy, poor dermal extensibility, and thin subcutaneous tissue. The use of bulky internal fixation material can thus cause the swel... Introduction: Pilon fracture in elderly individuals is characterized by senile skin atrophy, poor dermal extensibility, and thin subcutaneous tissue. The use of bulky internal fixation material can thus cause the swelling that accompanies the fracture to induce secondary injury to skin tissue. In addition, initiation of postoperative weight-bearing is delayed due to bone fragility and difficulties with partial weight-bearing, causing a tendency toward prolonged hospitalization. Mean duration of hospitalization after pilon fracture for elderly patients in our department was 79.2 days. Case Presentation: An 80-year-old woman with pilon fracture with soft tissue injury and severe osteoporosis was transferred to our department. The fracture was treated using Ilizarov external fixation. Fourteen days postoperatively, walking with full weight-bearing was permitted. The hospital stay was 28 days. The external fixator of the ankle was removed 87 days postoperatively, at which time the patient was anatomically and functionally recovered and able to walk unaided. Conclusion: Ilizarov external fixation may represent a useful option in elderly patients with pilon fracture showing severe soft tissue injury and severe osteoporosis. The present case provides evidence that this procdure can be successfully applied to the management of such pilon fractures in elderly patients. 展开更多
关键词 ILIZAROV External FIXATION ELDERLY Patient PILON Fracture soft tissue Injury OSTEOPOROSIS
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A New Model to Study Healing of a Complex Femur Fracture with Concurrent Soft Tissue Injury in Sheep 被引量:1
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作者 Martin E. Wullschleger Roland Steck +5 位作者 Romano Matthys John D. Webster Maria A. Woodruff Devakar R. Epari Keita Ito Michael A. Schuetz 《Open Journal of Orthopedics》 2013年第2期62-68,共7页
High energy bone fractures resulting from impact trauma are often accompanied by subcutaneous soft tissue injuries, even if the skin remains intact. There is evidence that such closed soft tissue injuries affect the h... High energy bone fractures resulting from impact trauma are often accompanied by subcutaneous soft tissue injuries, even if the skin remains intact. There is evidence that such closed soft tissue injuries affect the healing of bone fractures, and vice versa. Despite this knowledge, most impact trauma studies in animals have focussed on bone fractures or soft tissue trauma in isolation. However, given the simultaneous impact on both tissues a better understanding of the interaction between these two injuries is necessary to optimise clinical treatment. The aim of this study was therefore to develop a new experimental model and characterise, for the first time, the healing of a complex fracture with concurrent closed soft tissue trauma in sheep. A pendulum impact device was designed to deliver a defined and standardised impact to the distal thigh of sheep, causing a reproducible contusion injury to the subcutaneous soft tissues. In a subsequent procedure, a reproducible femoral butterfly fracture (AO C3-type) was created at the sheep’s femur, which was initially stabilised for 5 days by an external fixator construct to allow for soft tissue swelling to recede, and ultimately in a bridging construct using locking plates. The combined injuries were applied to twelve sheep and the healing observed for four or eight weeks (six animals per group) until sacrifice. The pendulum impact led to a moderate to severe circumferential soft tissue injury with significant bruising, haematomas and partial muscle disruptions. Posttraumatic measurements showed elevated intra-compartmental pressure and circulatory tissue breakdown markers, with recovery to normal, pre-injury values within four days. Clinically, no neurovascular deficiencies were observed. Bi-weekly radiological analysis of the healing fractures showed progressive callus healing over time, with the average number of callus bridges increasing from 0.4 at two weeks to 4.2 at eight weeks. Biomechanical testing after sacrifice showed in- creasing torsional stiffness between four and eight weeks healing time from 10% to 100%, and increasing ultimate torsional strength from 10% to 64% (relative to the contralateral control limb). Our results demonstrate the robust healing of a complex femur fracture in the presence of a severe soft tissue contusion injury in sheep and demonstrate the establishment of a clinically relevant experimental model, for research aimed at improving the treatment of bone fractures accompanied by closed soft tissue injuries. 展开更多
关键词 Fracture OVINE Large ANIMAL Model Bone soft tissue INJURY
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EIGHTY CASES of SOFT TISSUE INJURY TREATED WITH LOCAL CONTRALATERAL NEEDLING METHOD
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作者 Jin YanliDept. of Acupuncture and Moxibustion,Beijing College of Acupuncture and Orthopaedics,Beijing 100015, China 《World Journal of Acupuncture-Moxibustion》 1995年第1期30-32,共3页
Contralateral needling method is a common and effective one of acupuncture analgesicmethods.It is used to treat a local pain in the limbs and trunk with a short course of disease,pain and swelling will disappear or be... Contralateral needling method is a common and effective one of acupuncture analgesicmethods.It is used to treat a local pain in the limbs and trunk with a short course of disease,pain and swelling will disappear or be relieved immediately for one or two treatments.Really,there isan effect of relieving pain as soon as the needle is inserted.When the local contralateral needlingmethod is used,the key to improving the effectiveness lies in determining the pain position and its correspondingpoint correctly,the more correct the pain position and its corresponding point are determined,the better the effectiveness will be.In this group,80 cases soft tissue injury were treatedwith local contralateral needling method,the cure rate was 82%,and the total effective rate was100%. 展开更多
关键词 CONTRALATERAL NEEDLING METHOD soft tissue INJURY PAIN
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Experimental study on early repair of oromaxillofacial perforating soft tissue defect due to gunshot in dogs
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作者 李慧增 孙远 +3 位作者 刘荫秋 史文进 容国俊 周宝桐 《Journal of Medical Colleges of PLA(China)》 CAS 1993年第2期148-151,共4页
The left cheek of 8 adult male mongrel dogs was shot with M1935.56mm bul-let fired through an US-made M16 rifle to result in a perforating soft tissue defect.Pri-mary debridement was performed immediately and the seco... The left cheek of 8 adult male mongrel dogs was shot with M1935.56mm bul-let fired through an US-made M16 rifle to result in a perforating soft tissue defect.Pri-mary debridement was performed immediately and the secondary debridement 72h alter in-jury.After the secondary thorough debridement,the cutaneous side of the defect was re-paired with a saphenous artery-vein free skin(muscular)flap using microvascularanastomosis,and the oral side of the defect was repaired by drawing the surroundingmucosa together and fixing with sutures or with a local sliding mucous membrane flap.All the animals were kept under observation for 2~6 months.It was believed that the pri-mary debridement and secondary thorough debridement were both essential. The survivalrate of the free tissue flap was 75%(6/8).These facts suggest that early repair ofthe oromaxillofacial perforating soft tissue defect due to gunshot is practicable. 展开更多
关键词 oromaxillofacial region GUNSHOT INJURY PERFORATING soft tissue DEFECT reconstruction surgery MICROsuRGERY
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Electrical Resistance as A Measure of Soft Tissue Injuryfrom Delayed Onset Muscle Soreness
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作者 Timothy Hui Jerrold Petrofsky Iman Akef Khowailed 《Journal of Health Science》 2014年第8期353-362,共10页
Assessment of muscle damage relies commonly on subjective sensation of pain. The purpose of this research was to test thevalidity of microcurrent conductance on skin over injured tissue to quantify soft tissue injury ... Assessment of muscle damage relies commonly on subjective sensation of pain. The purpose of this research was to test thevalidity of microcurrent conductance on skin over injured tissue to quantify soft tissue injury and recovery following heavy exercisecompared to other indexes of muscle soreness. A randomized, controlled, single-blinded, 1-week trial on 60 subjects.Setting-University Interventions: Subjects did 3 sets of squats for 5 min each. There were 3 groups of 20 subjects. One did nothing andone had heat applied for 8 h post exercise. The final group had heat 24 h after exercise. Tissue resistance and muscle strength force tomove the knee, analog visual pain scale. In the control group, microcurrent continually decreased, eventually decreasing 32% by thethird day post exercise. When heat was given immediately following exercise, microcurrent was 26% greater (P 〈 0.001). The painscale rose to 3.1/10 as opposed to 5.4/10 for controls. Strength and muscle elasticity stayed mostly constant after heat as opposed to a28% decrease in strength and increase in stiffness in the control subjects. For 24 h delayed heat, microcurrent was 14% greater(P 〈 0.02), and was unchanged for the first 24 h when no therapy was given. Pain scale rose to 4.8/10. Stiffness was unchanged whilemuscle strength decreased the same as controls. Microcurrent shows agreement with loss of strength, and stiffness from DOMS but notthe subjective pain measure. It appears that microcurrent is a good measure of muscle damage. 展开更多
关键词 Microcurrent conductance soft tissue injury recovery.
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TREATMENT OF SOFT TISSUE INJURY BY PUNCTURING CLEFT-POINTS
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作者 许云祥 陈贵珍 《World Journal of Acupuncture-Moxibustion》 2001年第4期23-26,共4页
Objective: To observe the therapeutic effect of acupuncture of "Xi" (Cleft) points in treatment of soft tissue injury. Methods: 335 cases of soft tissue injury patients were divided into Cleft point group (2... Objective: To observe the therapeutic effect of acupuncture of "Xi" (Cleft) points in treatment of soft tissue injury. Methods: 335 cases of soft tissue injury patients were divided into Cleft point group (264 cases) and Ashi point group (control group, 71 cases) randomly. In Cleft point group, the 16 Cleft points were used in combination with Ahshi points. In control group, only local Ahshi points were punctured. The treatment was conducted once every day, with 5 sessions being a therapeutic course. After 2 courses of treatment, the therapeutic effect was analyzed. Results: Results showed that the therapeutic effect of cleft point group was significantly better than that of control group (P<0.05), particularly in treatment of acute soft tissue. Conclusion: Cleft point acupuncture has a better therapeutic effect in treatment of soft tissue injury in comparison with Ashi point. 展开更多
关键词 中医 针刺疗法 腧穴 针灸
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Minimizing treatment complexity of combat-related soft tissue injuries using a dedicated tension relief system and negative pressure therapy augmented by high-dose in situ antibiotic therapy and oxygen delivery: a retrospective study 被引量:8
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作者 Moris Topaz Itamar Ashkenazi +4 位作者 Oren Barzel Seema Biswas Dan Atar Nurit Shadmi Itzhak Siev-Ner 《Burns & Trauma》 SCIE 2021年第1期454-463,共10页
Background:Following combat-related,extensive soft tissue injury from gunshot wounds or blasts,prolonged duration from injury to full wound closure is associated with infection,increased morbidity and mortality,failur... Background:Following combat-related,extensive soft tissue injury from gunshot wounds or blasts,prolonged duration from injury to full wound closure is associated with infection,increased morbidity and mortality,failure to mobilize,poor functional outcome and increased cost.The purpose of this study was to evaluate a novel treatment enabling early primary closure of combat wounds.Methods:This was a retrospective study of 10 soldiers and civilians with extensive combat-related soft tissue limb injuries(5 gunshot wounds,5 blasts)treated using the TopClosure^(■)Tension Relief System(TRS)with simultaneous administration of regulated oxygen-enriched and irrigation negative pressure-assisted wound therapy(ROINPT)via the Vcareα^(■)device.Results:Nine patients were treated during the acute phase of injury and one was treated following removal of a flap due to deep infection 20 years after injury and flap reconstruction.Two patients had upper limb injury and the rest lower limb injury.With the aid of the TRS and/or ROINPT,immediate primary closure during reconstruction was achieved in 6 patients and delayed primary closure in three.Only one patient required a skin graft to close a small area of the wound after most of the wound had been closed by delayed primary closure.Wound closure was achieved within 0–37 days(median:12.5 days,interquartile range:2.75–19.75)from injury.Conclusions:The TRS is a novel device for effective,early skin stretching and secure wound closure through the application of stress relaxation and mechanical creep,achieving primary closure of large defects using a simplified surgical technique and reducing the need for closure using skin grafts and flaps and the use of tissue expanders.Delivering supplemental oxygen to the wound by ROINPT reverses the reduced oxygen levels inherent in conventional negative pressure-assisted wound therapy,mitigating anaerobic contamination and reducing infection.Irrigation may accelerate the evacuation of infectious material from the wound and provide a novel method for antibiotic administration.The combination of TRS and ROINPT devices allow for early primary closure with improved functionality of combat-related limb injuries. 展开更多
关键词 soft tissue injury Combat injuries Limb injuries Stress relaxation Mechanical creep Tension relief systems
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Analgesic Effect of Sinew Acupuncture for Patients with Soft-Tissue Injuries: A Pilot Trial 被引量:4
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作者 CHEN Hai-yong LIU Nong-yu 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2019年第8期613-616,共4页
Objective: To investigate the immediate analgesic effect of sinew acupuncture for patients with soft-tissue injuries (STIs). Methods: Two hundreds eligible adult patients suffering from STIs were recruited and receive... Objective: To investigate the immediate analgesic effect of sinew acupuncture for patients with soft-tissue injuries (STIs). Methods: Two hundreds eligible adult patients suffering from STIs were recruited and received sinew acupuncture with flexible treatment schedules. The number of treatment sessions was pragmatically decided by each patient on the basis of their pain relief. The outcome measurement was the change of pain rating in the Visual Analogue Scale (VAS) during the first 5 sessions. The adverse effect was also observed. Results: Of the 200 patients recruited, 7 were excluded due to incomplete data. In total, 888 sinew acupuncture treatments were administered to patients at 14 injury sites (including head, neck, shoulder, arm, chest, elbow, wrist, hand, waist and hip, knee, thigh, calf, ankle, and foot) where pain was felt. Compared with the baseline, the VAS rating after the first and last treatments were both significantly reduced at all the injury sites (P<0.01). The VAS rating was also significantly reduced after each session of treatment in the first five sessions (P<0.01). No serious adverse effect was observed. Conclusion: Sinew acupuncture had not only an immediate analgesic effect for STIs, but also an accumulated analgesic effect during the first 5 treatment sessions. 展开更多
关键词 sinew ACUPUNCTURE soft-tissue injury ANALGESIC effect PAIN Visual ANALOGUE Scale
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Observation on Therapeutic Effect in Acupuncture Treatment of Soft Tissue Injuries by Differentiation of Deficient and Excessive Patterns 被引量:2
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作者 杨翊 周光涛 黄国琪(译) 《Journal of Acupuncture and Tuina Science》 2006年第3期186-188,共3页
目的:比较虚实辨证针刺法与常规循经刺法治疗软组织损伤的疗效差异。方法:将380例软组织损伤患者随机分为辨证组(200例,虚实辨证刺法)与循经组(180例,循经取穴刺法),观察比较两组疗效。结果:辨证组的痊愈率为86%,循经组为31.11%,差异有... 目的:比较虚实辨证针刺法与常规循经刺法治疗软组织损伤的疗效差异。方法:将380例软组织损伤患者随机分为辨证组(200例,虚实辨证刺法)与循经组(180例,循经取穴刺法),观察比较两组疗效。结果:辨证组的痊愈率为86%,循经组为31.11%,差异有非常显著性意义(P<0.01);从痊愈好转病例的总平均治疗时间比较,辨证组为8.8 d,循经组为15.6 d,差异有非常显著性意义(P<0.01),辨证组明显优于循经组。结论:治疗软组织损伤,虚实辨证针刺法优于常规循经刺法。 展开更多
关键词 软组织损伤 针刺疗法 辨证分型
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Soft tissue compartment bleed-the iceberg phenomenon:a case report
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作者 Ramesh Vaidyanathan Parvez Mohi Ud Din Dar +1 位作者 Dinesh Bagaria Amit Gupta 《Emergency and Critical Care Medicine》 2023年第1期32-35,共4页
Introduction:Hemorrhage control is the essence of trauma care.Conventional teaching is 1 on the floor(ie,external bleeding)and 4 more(thoracic cavity,abdomen,retroperitoneum,and long bones).In this case report,we pres... Introduction:Hemorrhage control is the essence of trauma care.Conventional teaching is 1 on the floor(ie,external bleeding)and 4 more(thoracic cavity,abdomen,retroperitoneum,and long bones).In this case report,we present a unique case with concealed bleeding into the soft tissue compartment leading to shock.This case triggered to consider the soft tissue compartment as the sixth potential bleeding site in trauma patients in hemorrhagic shock.Case presentation:We present the case with concealed bleeding into the soft tissue compartment posing a challenge in management.On presentation,he had a pulse rate of 117 beats/min,a blood pressure of 90/60mmHg,and a Glasgow Coma Scale(GCS)score of 9.During resuscitation,the patient's blood pressure dropped to 70/46 mmHg with a GCS of 7 of 15.He was then intubated and reevaluated.Contrast-enhanced computed tomography of the torso revealed a right scapular fracture with a large soft tissue hematoma along the right side of the neck and chest wall,extending up to the right lumbar region.Conclusion:We suggest that the soft tissue compartment is the sixth potential site of internal bleeding in trauma patients,which should not be overlooked after having ruled out the other 5 sites. 展开更多
关键词 Case report HEMORRHAGE Shock soft tissue injury TRAUMA
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化瘀止痛贴膏调节IL-6/STAT3信号通路对急性软组织损伤大鼠炎症反应的影响
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作者 王适 胡立志 +2 位作者 左姿 王敏 聂孝平 《西部医学》 2024年第6期820-825,共6页
目的探讨化瘀止痛贴膏调节白细胞介素-6(IL-6)/信号转导与转录激活子3(STAT3)信号通路对急性软组织损伤(ASTI)大鼠炎症反应的影响。方法将SPF级SD大鼠随机分为对照组、模型组、化瘀止痛贴膏低、中、高剂量组、精制狗皮膏组。利用机械冲... 目的探讨化瘀止痛贴膏调节白细胞介素-6(IL-6)/信号转导与转录激活子3(STAT3)信号通路对急性软组织损伤(ASTI)大鼠炎症反应的影响。方法将SPF级SD大鼠随机分为对照组、模型组、化瘀止痛贴膏低、中、高剂量组、精制狗皮膏组。利用机械冲击挫伤法建立ASTI动物模型,建模成功后,各组贴敷相应药物,1次/d,每次给药8 h,连续7 d。对大鼠进行ASTI损伤评分;采用血液流变检测仪检测血液流变学指标;苏木精和伊红(HE)染色法观察大鼠损伤部位肌肉组织病理变化;酶联免疫吸附法(ELISA)检测各组大鼠损伤部位肌肉组织中IL-6、IL-β、肿瘤坏死因子-α(TNF-α)水平;实时荧光定量PCR(qRT-PCR)法检测损伤部位肌肉组织中IL-6与STAT3 mRNA表达;蛋白免疫印迹(Western blot)法检测大鼠损伤部位肌肉组织中IL-6/STAT3信号通路蛋白表达。结果与对照组比较,模型组大鼠软组织损伤评分、全血黏度、血浆黏度、红细胞压积、肌肉组织病理学评分、IL-6、IL-β、TNF-α水平、IL-6与STAT3 mRNA表达水平及IL-6、p-STAT3/STAT3蛋白表达水平升高(均P<0.05);与模型组比较,化瘀止痛贴膏低、中、高剂量组和狗皮膏药组大鼠软组织损伤评分、全血黏度、血浆黏度、红细胞压积、肌肉组织病理学评分、IL-6、IL-β、TNF-α水平、IL-6与STAT3 mRNA表达水平及IL-6、p-STAT3/STAT3蛋白表达水平降低(均P<0.05);化瘀止痛贴膏高剂量组与精制狗皮膏组大鼠以上指标差异均无统计学意义(P>0.05)。结论化瘀止痛贴膏可能通过下调IL-6/STAT3信号通路缓解ASTI大鼠的炎症反应。 展开更多
关键词 化瘀止痛贴膏 白细胞介素-6/信号转导与转录激活子3 急性软组织损伤 炎症反应
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四肢创伤性软组织缺损患者游离皮瓣移植失败的危险因素及预测模型构建
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作者 宋春林 罗成军 朱雨 《组织工程与重建外科》 CAS 2024年第3期305-311,共7页
目的探讨四肢创伤性软组织缺损(STI)患者游离皮瓣移植(FFT)修复失败的危险因素,并构建预测模型。方法选取2017年1月至2023年6月期间行FFT的575例四肢创伤性STI患者为研究对象,7︰3随机分为建模组(n=403)和验证组(n=172)。多因素Logisti... 目的探讨四肢创伤性软组织缺损(STI)患者游离皮瓣移植(FFT)修复失败的危险因素,并构建预测模型。方法选取2017年1月至2023年6月期间行FFT的575例四肢创伤性STI患者为研究对象,7︰3随机分为建模组(n=403)和验证组(n=172)。多因素Logistic回归分析确定四肢创伤性STI患者FFT修复失败的危险因素。利用R3.6.3软件中rms程序包构建预测四肢创伤性STI患者FFT修复失败的列线图模型,并采用受试者工作特征(ROC)曲线和霍斯默-莱梅肖(H-L)拟合度曲线,对列线图模型预测区分度和一致性进行评估。结果多因素Logistic回归分析显示,受伤至手术时间≥6 h(OR=2.179)、吻合血管选择不合理(OR=6.770)、并发感染(OR=4.980)、术中止血不彻底(OR=3.054)、术后固定不牢固(OR=2.132)等,均为四肢创伤性STI患者FFT修复失败的独立危险因素(P<0.05);建模组H-L检验χ^(2)=11.889、P=0.546,ROC曲线下面积为0.809(95%CI:0.748~0.869);验证组H-L检验χ^(2)=6.990、P=0.322,ROC曲线下面积为0.827(95%CI:0.722~0.932)。结论基于受伤至手术时间、吻合血管选择、并发感染、术中止血不彻底、术后固定不牢固等5个危险因素构建的预测四肢创伤性STI患者FFT修复失败的列线图模型具有较好的区分度和一致性。 展开更多
关键词 四肢创伤性软组织缺损 游离皮瓣移植 危险因素 预测模型
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基于气滞血瘀理论探讨五虎口服液治疗急性软组织损伤的疗效
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作者 廖乐乐 毛敏之 +2 位作者 刘开宇 何桄旭 李丁 《西部医学》 2024年第6期855-860,共6页
目的基于气滞血瘀理论探讨五虎口服液治疗急性软组织损伤的疗效。方法选取2020年9月—2022年9月于我院就诊的130例急性软组织损伤(ASTI)患者作为研究对象,通过随机数字表法分为研究组(65例)和对照组(65例),对照组给予吲哚美辛巴布膏治疗... 目的基于气滞血瘀理论探讨五虎口服液治疗急性软组织损伤的疗效。方法选取2020年9月—2022年9月于我院就诊的130例急性软组织损伤(ASTI)患者作为研究对象,通过随机数字表法分为研究组(65例)和对照组(65例),对照组给予吲哚美辛巴布膏治疗,研究组在对照组基础上给予五虎口服液治疗。并建立五虎口服液治疗ASTI的效益与风险多准则决策分析模型。采用RevMan5.3软件合并数据,得出各效益指标和风险指标效应值,采用Hiview3软件计算出研究组和对照组的效益值、风险值和效益-风险总值,改变效益-风险中一级指标的权重来评价模型的灵敏度。结果治疗后,研究组患者在压痛、瘀斑、肿胀、功能障碍、VAS评分、疼痛缓解时间、肿胀缓解时间、不良反应、临床疗效、功能障碍缓解时间方面改善显著优于对照组(均P<0.05);且IL-6、TNF-α水平均显著低于对照组(P<0.05),其余指标比较差异无统计学意义(P>0.05);研究组和对照组的效益值分别为66和50,风险值分别为71和83,效益-风险总值分别为67、57。研究组的效益-风险总值最高。无论效益-风险的相对权重如何改变,模型评价结果均保持不变,表明该模型稳定型良好。结论基于气滞血瘀理论下,五虎口服液治疗ASTI获益高于风险,可降低不良反应的发生率,能够为临床合理用药提供依据。 展开更多
关键词 五虎口服液 急性软组织损伤 气滞血瘀 疗效 模型
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胫骨远端骨折伴软组织损伤3种不同微创固定方式的有限元分析 被引量:1
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作者 王明明 张中 +4 位作者 孙建华 赵刚 宋华 颜华东 吕彬 《中国组织工程研究》 CAS 北大核心 2024年第6期879-885,共7页
背景:伴软组织损伤胫骨远端骨折的治疗一直具有挑战性,新型逆行胫骨髓内钉是一种新的选择。目前关于新型逆行胫骨髓内钉、顺行髓内钉、外置接骨板之间的生物力学性能研究未见报道。目的:通过有限元分析方法,探讨新型逆行胫骨髓内钉、顺... 背景:伴软组织损伤胫骨远端骨折的治疗一直具有挑战性,新型逆行胫骨髓内钉是一种新的选择。目前关于新型逆行胫骨髓内钉、顺行髓内钉、外置接骨板之间的生物力学性能研究未见报道。目的:通过有限元分析方法,探讨新型逆行胫骨髓内钉、顺行髓内钉、外置接骨板治疗伴软组织损伤胫骨远端骨折的生物力学稳定性,为临床应用提供科学参考。方法:利用1名42岁健康男性的胫骨CT数据,通过相关软件建立胫骨远端横行骨折的有限元模型,根据骨折的固定原则,构建新型胫骨逆行髓内钉、胫骨顺行髓内钉、外置股骨远端外侧接骨板固定有限元模型。使用ANSYS 2019软件进行网格划分、施加载荷、数据处理,比较各模型胫骨和内固定的应力分布及位移情况。结果与结论:(1)3组模型的骨折端位移量随着载荷的增大而增加;所有模式载荷中,逆行髓内钉组位移最小,外置接骨板组次之,顺行髓内钉组平均位移最大;在800 N垂直载荷中,各组位移差异有显著性意义(P<0.05);其余载荷模式下各组无显著性差异;(2)不同载荷模式下3组模型中胫骨应力均表现为胫骨中段最高,向近、远端缓慢过渡降低;胫骨干部位应力分布均呈现逆行髓内钉组最高、外置接骨板组次之、顺行髓内钉组应力最小的情况;(3)不同载荷模式下3组模型中胫骨应力集中部位的应力,外置接骨板组明显高于另外两组,差异均有显著性意义(P<0.05);(4)不同载荷条件下3组模型中固定物的应力值,外置接骨板组最大,逆行髓内钉组次之,顺行髓内钉组最小;不同载荷条件下3组固定物应力集中部位的应力差异均有显著性意义(P<0.05);(5)提示3种固定方式均具有良好的抗旋转能力及轴向稳定性,其中新型胫骨逆行髓内钉具有更好的生物力学稳定性。 展开更多
关键词 胫骨远端骨折 微创 逆行钉 髓内钉 外置接骨板 有限元分析 生物力学 软组织损伤
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肌骨超声检查对创伤性浅表软组织损伤的临床诊断价值分析 被引量:1
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作者 郝云 门永忠 马新强 《医学影像学杂志》 2024年第1期100-103,共4页
目的探讨肌骨超声检查对创伤性浅表软组织损伤的临床诊断价值。方法选取本院收治的疑似创伤性浅表软组织损伤206例患者,均行超声检查及磁共振成像(Magnetic Resonance Imaging,MRI)检查,以手术病理检查结果为“金标准”,观察超声检查诊... 目的探讨肌骨超声检查对创伤性浅表软组织损伤的临床诊断价值。方法选取本院收治的疑似创伤性浅表软组织损伤206例患者,均行超声检查及磁共振成像(Magnetic Resonance Imaging,MRI)检查,以手术病理检查结果为“金标准”,观察超声检查诊断结果及其安全性与准确性、超声检查声像图特点。结果以手术病理检查结果为“金标准”,超声检查与MRI检查两种方式对诊断效能、损伤类型及阳性预测值与阴性预测值比较,差异无统计学意义(P>0.05),但MRI检查对半月板撕裂检出率高于超声检查,差异有统计学意义(P<0.05)。12例神经损伤患者超声检查可见受压部位横断面减小,回声逐渐降低,彩色多普勒检查可探及少量血流信号;19例实性肿块患者声像图可见形态不规则回声区,边缘模糊,多普勒探查无血流信号;28例囊性肿块患者声像图可见部分液性暗区或无回声区,部分可探及血流信号,边缘清晰;24例韧带撕裂患者声像图可见患侧韧带弥漫性增厚且回声减低、结构紊乱,并可见血流信号;15例肌腱损伤患者声像图可见呈条带状低回声,且有连续性中断伴裂隙样低回声,断端可见血流信号;61例半月板撕裂患者声像图显示半月板连续性中断伴内部不均匀回声,彩色多普勒检查可探及血流信号。结论肌骨超声检查在创伤性浅表软组织损伤的检查中,可有效鉴别损伤类型及其范围,准确率较高,可作为患者初步筛查手段,且具有无创、安全及可重复性等优点,应用价值高。 展开更多
关键词 创伤性浅表软组织损伤 超声检查 声像图特点 安全性 准确性
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带蒂旋髂浅动脉穿支皮瓣与躯干任意皮瓣修复手部电击伤致软组织缺损疗效对比 被引量:1
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作者 孙佳琳 郑伟才 +1 位作者 李庆华 樊磊 《中国烧伤创疡杂志》 2024年第3期196-200,共5页
目的对比分析带蒂旋髂浅动脉穿支皮瓣与躯干任意皮瓣修复手部电击伤致软组织缺损的临床疗效。方法选取2017年5月至2022年6月河南科技大学第一附属医院收治的82例手部电击伤致软组织缺损患者作为研究对象,按照不同治疗方式将其分为试验组... 目的对比分析带蒂旋髂浅动脉穿支皮瓣与躯干任意皮瓣修复手部电击伤致软组织缺损的临床疗效。方法选取2017年5月至2022年6月河南科技大学第一附属医院收治的82例手部电击伤致软组织缺损患者作为研究对象,按照不同治疗方式将其分为试验组(40例)和对照组(42例),试验组患者软组织缺损创面采用带蒂旋髂浅动脉穿支皮瓣进行修复,对照组患者软组织缺损创面采用躯干任意皮瓣进行修复,对比观察两组患者皮瓣血管蒂长度、住院时间、创面愈合时间、手指关节总主动活动度、皮瓣受区支配区域感觉功能与并发症(淋巴瘘、血管危象、瘢痕挛缩)发生情况。结果试验组患者皮瓣血管蒂长度为(789±113)cm,明显长于对照组患者的皮瓣血管蒂长度(629±121)cm(t=6181,P<0001);住院时间为(3114±492)d、创面愈合时间为(4019±1023)d,明显短于对照组患者的住院时间(3358±503)d、创面愈合时间(4662±1141)d(t=2219、2682,P=0029、0009)。术后4个月,试验组患者手指关节总主动活动度为良20例、中16例、差4例,明显优于对照组患者的手指关节总主动活动度为良10例、中20例、差12例(Z=-2762,P=0006);试验组患者皮瓣受区支配区域感觉功能为5级8例、4级12例、3级11例、2级7例、1级2例,明显优于对照组患者的皮瓣受区支配区域感觉功能为5级1例、4级10例、3级10例、2级13例、1级7例、0级1例(Z=-3005,P=0002)。试验组患者术后并发症发生率为1750%,明显低于对照组患者的术后并发症发生率4048%(χ^(2)=5224,P=0022)。结论与躯干任意皮瓣相比,带蒂旋髂浅动脉穿支皮瓣可有效修复手部电击伤所致的软组织缺损,促进手部运动功能及感觉功能恢复,降低淋巴瘘等并发症发生率。 展开更多
关键词 带蒂旋髂浅动脉穿支皮瓣 任意皮瓣 电击伤 软组织缺损 总主动活动度 感觉功能
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