BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely a...BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.展开更多
目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的...目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的方法为患者进行治疗,观察组采用软通道穿刺引流术为患者进行治疗,比较两组治疗效果。结果与对照组比较,观察组中等量高血压脑出血患者的救治成功率更高,治疗有效性更高,术后并发症发生率更低,且经过治疗后的临床神经功能缺损评分(national institute of health stroke scale,NIHSS)更低,生活质量和睡眠质量更高(P<0.05)。结论针对中等量高血压脑出血患者,采取软通道穿刺引流术的效果更优,患者的治疗有效性和神经功能状况得到改善,并发症情况较低,且患者治疗后生活质量和睡眠质量得到提升,治疗优势突出,可在临床大量推广。展开更多
文摘BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.
文摘目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的方法为患者进行治疗,观察组采用软通道穿刺引流术为患者进行治疗,比较两组治疗效果。结果与对照组比较,观察组中等量高血压脑出血患者的救治成功率更高,治疗有效性更高,术后并发症发生率更低,且经过治疗后的临床神经功能缺损评分(national institute of health stroke scale,NIHSS)更低,生活质量和睡眠质量更高(P<0.05)。结论针对中等量高血压脑出血患者,采取软通道穿刺引流术的效果更优,患者的治疗有效性和神经功能状况得到改善,并发症情况较低,且患者治疗后生活质量和睡眠质量得到提升,治疗优势突出,可在临床大量推广。
