Software Defined Networking(SDN)is programmable by separation of forwarding control through the centralization of the controller.The controller plays the role of the‘brain’that dictates the intelligent part of SDN t...Software Defined Networking(SDN)is programmable by separation of forwarding control through the centralization of the controller.The controller plays the role of the‘brain’that dictates the intelligent part of SDN technology.Various versions of SDN controllers exist as a response to the diverse demands and functions expected of them.There are several SDN controllers available in the open market besides a large number of commercial controllers;some are developed tomeet carrier-grade service levels and one of the recent trends in open-source SDN controllers is the Open Network Operating System(ONOS).This paper presents a comparative study between open source SDN controllers,which are known as Network Controller Platform(NOX),Python-based Network Controller(POX),component-based SDN framework(Ryu),Java-based OpenFlow controller(Floodlight),OpenDayLight(ODL)and ONOS.The discussion is further extended into ONOS architecture,as well as,the evolution of ONOS controllers.This article will review use cases based on ONOS controllers in several application deployments.Moreover,the opportunities and challenges of open source SDN controllers will be discussed,exploring carriergrade ONOS for future real-world deployments,ONOS unique features and identifying the suitable choice of SDN controller for service providers.In addition,we attempt to provide answers to several critical questions relating to the implications of the open-source nature of SDN controllers regarding vendor lock-in,interoperability,and standards compliance,Similarly,real-world use cases of organizations using open-source SDN are highlighted and how the open-source community contributes to the development of SDN controllers.Furthermore,challenges faced by open-source projects,and considerations when choosing an open-source SDN controller are underscored.Then the role of Artificial Intelligence(AI)and Machine Learning(ML)in the evolution of open-source SDN controllers in light of recent research is indicated.In addition,the challenges and limitations associated with deploying open-source SDN controllers in production networks,how can they be mitigated,and finally how opensource SDN controllers handle network security and ensure that network configurations and policies are robust and resilient are presented.Potential opportunities and challenges for future Open SDN deployment are outlined to conclude the article.展开更多
Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass materials.These materials offer numerous advantages such as being lightweight,porous,and...Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass materials.These materials offer numerous advantages such as being lightweight,porous,and hierarchical.Due to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EMI shielding materials.Despite concerted efforts on the EMI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EMI shielding materials.In particular,a more comprehensive study and summary of the factors influencing biomass EMI shielding materials including the pore structure adjustment,preparation process,and micro-control would be valuable.The preparation methods and characteristics of wood,bamboo,cellulose and lignin in EMI shielding field are critically discussed in this paper,and similar biomass EMI materials are summarized and analyzed.The composite methods and fillers of various biomass materials were reviewed.this paper also highlights the mechanism of EMI shielding as well as existing prospects and challenges for development trends in this field.展开更多
Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury level.However,because of prolonged inactivity,initial attempts to activate these...Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury level.However,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface electromyography.In this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord injury.Eleven patients with chronic complete thoracic spinal cord injury were recruited.Surface electromyography data from eight major leg muscles were acquired and compared before and after the passive activity protocol.The results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of activation.Although the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically significant.These findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.展开更多
Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug deliv...Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug delivery often results in a burst release of the drug,leading to transient retention(inefficacy)and undesirable diffusion(toxicity)in vivo.Therefore,a drug delivery system that responds to changes in the microenvironment of tissue regeneration and controls vascular endothelial growth factor release is crucial to improve the treatment of ischemic stroke.Matrix metalloproteinase-2(MMP-2)is gradually upregulated after cerebral ischemia.Herein,vascular endothelial growth factor mimic peptide QK was self-assembled with MMP-2-cleaved peptide PLGLAG(TIMP)and customizable peptide amphiphilic(PA)molecules to construct nanofiber hydrogel PA-TIMP-QK.PA-TIMP-QK was found to control the delivery of QK by MMP-2 upregulation after cerebral ischemia/reperfusion and had a similar biological activity with vascular endothelial growth factor in vitro.The results indicated that PA-TIMP-QK promoted neuronal survival,restored local blood circulation,reduced blood-brain barrier permeability,and restored motor function.These findings suggest that the self-assembling nanofiber hydrogel PA-TIMP-QK may provide an intelligent drug delivery system that responds to the microenvironment and promotes regeneration and repair after cerebral ischemia/reperfusion injury.展开更多
The quality control chart of fructo-oligosaccharides in milk powder was established to determine whether the detection process and results are in control state.The content of fructo-oligosaccharides in milk powder con...The quality control chart of fructo-oligosaccharides in milk powder was established to determine whether the detection process and results are in control state.The content of fructo-oligosaccharides in milk powder control samples was determined by ion chromatography,and the quality control chart of fructo-oligosaccharides was established to analyze the controlled state.The results indicate that the median of the quality control chart is 1613.14 mg/100 g,and the standard deviation is 85.57 mg/100 g.The new quality control points were evaluated and analyzed,and the precision changed,but the mean value did not change.Further F test was conducted to determine that the precision did not change significantly,indicating that the test was in a statistical control state,and the detection process,method and results were controlled.展开更多
Gualou-Xiebai-Banxia Decoction(GXBD)is a traditional Chinese herbal formula including four traditional Chinese medicines:Gualou(Trichosanthis Fructus,TF),Xiebai(Allii Macrostemonis Bulbus,AMB),Banxia(Pinelliae Rhizoma...Gualou-Xiebai-Banxia Decoction(GXBD)is a traditional Chinese herbal formula including four traditional Chinese medicines:Gualou(Trichosanthis Fructus,TF),Xiebai(Allii Macrostemonis Bulbus,AMB),Banxia(Pinelliae Rhizoma,PR)and yellow wine.It is a classical therapy for chest stuffiness and pain syndrome and is widely used in the clinical treatment of coronary heart disease.It also shows significant therapeutic effects on pulmonary heart disease,hyperlipidemia,and arrhythmia.This study conducted a literature review and collected information on GXBD from databases such as PubMed,Web of Science,China National Knowledge Infrastructure,and ScienceDirect.The result indicated that the main active ingredients of GXBD are steroids,flavonoids,terpenoids,alkaloids,amino acids,and organic acids.Trigonelline,macrostemonoside and cucurbitacin B can provide reference for its quality control.GXBD may exert therapeutic effects on coronary heart disease through AMPK,PI3K-AKT,oxLDL,VEGF,and NF-κB signal pathways.This review provides a comprehensive analysis and summary of the chemical composition and in vivo metabolism of three traditional Chinese medicines(TF,AMB,and PR),along with an evaluation of the chemical composition,quality control,pharmacological effects,and clinical application of GXBD.Based on these,areas requiring further research on GXBD have been proposed to provide a reference for its further development and new drug research.展开更多
This study highlights the importance of identifying and addressing risk factors associated with wound complications following transtibial amputation in diabetic patients.These amputations,often necessitated by severe ...This study highlights the importance of identifying and addressing risk factors associated with wound complications following transtibial amputation in diabetic patients.These amputations,often necessitated by severe diabetic foot ulcers,carry significant risks of postoperative complications such as infection and delayed wound healing.Elevated hemoglobin A1c levels,indicative of poor glycemic control,and a history of kidney transplantation,due to required immunosuppressive therapy,are key factors influencing these outcomes.This paper emphasizes the need for enhanced glycemic management and personalized postoperative care,particularly for immunocompromised individuals,to minimize complications and improve patient prognosis.Future research should focus on prospective studies to validate targeted interventions and optimize care strategies,ultimately aiming to reduce the healthcare burden associated with diabetic foot complications.展开更多
Software defined optical networking(SDON)is a critical technology for the next generation network with the advantages of programmable control and etc.As one of the key issues of SDON,the security of control plane has ...Software defined optical networking(SDON)is a critical technology for the next generation network with the advantages of programmable control and etc.As one of the key issues of SDON,the security of control plane has also received extensive attention,especially in certain network scenarios with high security requirement.Due to the existence of vulnerabilities and heavy overhead,the existing firewalls and distributed control technologies cannot solve the control plane security problem well.In this paper,we propose a distributed control architecture for SDON using the blockchain technique(BlockCtrl).The proposed BlockCtrl model introduces the advantages of blockchain into SDON to achieve a high-efficiency fault tolerant control.We have evaluated the performance of our proposed architecture and compared it to the existing models with respect to various metrics including processing rate,recovery latency and etc.The numerical results show that the BlockCtrl is capable of attacks detection and fault tolerant control in SDON with high performance on resource utilization and service correlation.展开更多
The previous operation of the ZLS-Burris gravity meter using a PDA already provides a significant improvement of the operation of a metal spring gravity meter. But in the practical field work the observer usually wish...The previous operation of the ZLS-Burris gravity meter using a PDA already provides a significant improvement of the operation of a metal spring gravity meter. But in the practical field work the observer usually wishes more information about the measurement and the collected data. This situation sug- gested an improvement of the software and computer hardware. The goal was to develop a small useful PC tool that eliminates these deficits. However, it resulted in a very extensive application software, which was developed during 2011-2015. Along the way, some unwanted effects of the original control circuit were detected. Therefore as a last step a complete new control circuit for the feedback system was developed. This new circuit is fast and smooth and without resonance effects to the system. The algorithm parameters can be specifically adapted to the specific gravity meter. The software has a security system that ensures the user, depending on his level of knowledge, a limited access to the software options. Furthermore, a customer project management system is integrated. The observer, the gravity meters, the projects and maps can be assigned. Several ZLS Burris gravity meters can be managed. A large station data management is integrated. Every station has up to more than twenty parameters, such as the mandatory coordinates or supplementary pictures of the station. External storage and documentation of the measurements are possible with extra modules. In addition the maintenance of the gravity meter system is significantly improved. The motor control of the early ZLS Burris gravity meter is also improved. The complete rotation is displayed on the screen. Finally, two survey examples show the advantages of the software related to the accuracy and the time needed for a measurement.展开更多
This paper discusses the design and software-in-theloop implementation of adaptive formation controllers for fixedwing unmanned aerial vehicles(UAVs) with parametric uncertainty in their structure, namely uncertain ma...This paper discusses the design and software-in-theloop implementation of adaptive formation controllers for fixedwing unmanned aerial vehicles(UAVs) with parametric uncertainty in their structure, namely uncertain mass and inertia. In fact, when aiming at autonomous flight, such parameters cannot assumed to be known as they might vary during the mission(e.g.depending on the payload). Modeling and autopilot design for such autonomous fixed-wing UAVs are presented. The modeling is implemented in Matlab, while the autopilot is based on ArduPilot, a popular open-source autopilot suite. Specifically, the ArduP ilot functionalities are emulated in Matlab according to the Ardupilot documentation and code, which allows us to perform software-in-the-loop simulations of teams of UAVs embedded with actual autopilot protocols. An overview of realtime path planning, trajectory tracking and formation control resulting from the proposed platform is given. The software-inthe-loop simulations show the capability of achieving different UAV formations while handling uncertain mass and inertia.展开更多
A new method that designs and implements the component-based distributed & hierarchical flexible manufacturing control software is described with a component concept in this paper. The proposed method takes aim at...A new method that designs and implements the component-based distributed & hierarchical flexible manufacturing control software is described with a component concept in this paper. The proposed method takes aim at improving the flexibility and reliability of the control system. On the basis of describing the concepts of component-based software and the distributed object technology, the architecture of the component-based software of the control system is suggested with the Common Object Request Broker Architecture (CORBA). And then, we propose a design method for component-based distributed & hierarchical flexible manufacturing control system. Finally, to verify the software design method, a prototype flexible manufacturing control system software has been implemented in Orbix 2.3c, VC + + 6. 0 and has been tested in connection with the physical flexible manufacturing shop at the WuXi Professional Institute.展开更多
In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.I...In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.In this paper,we develop a flexible dormant multi-controller model based on the centralized multi-controller architecture.The dormant multi-controller model allows part of controllers to enter the dormant state under light traffic condition for saving system cost.Meanwhile,through queueing analysis,various performance measures of the system can be obtained.Moreover,we analyze the real traffic of China Education Network and use the results as the parameters of computer simulation and verify the effects of parameters on the system characteristics.Finally,a total expected cost function is established,and genetic algorithm is employed to find the optimal values of various parameters to minimize system cost for the deployment decision making.展开更多
The controller is indispensable in software-defined networking(SDN).With several features,controllers monitor the network and respond promptly to dynamic changes.Their performance affects the quality-of-service(QoS)in...The controller is indispensable in software-defined networking(SDN).With several features,controllers monitor the network and respond promptly to dynamic changes.Their performance affects the quality-of-service(QoS)in SDN.Every controller supports a set of features.However,the support of the features may be more prominent in one controller.Moreover,a single controller leads to performance,single-point-of-failure(SPOF),and scalability problems.To overcome this,a controller with an optimum feature set must be available for SDN.Furthermore,a cluster of optimum feature set controllers will overcome an SPOF and improve the QoS in SDN.Herein,leveraging an analytical network process(ANP),we rank SDN controllers regarding their supporting features and create a hierarchical control plane based cluster(HCPC)of the highly ranked controller computed using the ANP,evaluating their performance for the OS3E topology.The results demonstrated in Mininet reveal that a HCPC environment with an optimum controller achieves an improved QoS.Moreover,the experimental results validated in Mininet show that our proposed approach surpasses the existing distributed controller clustering(DCC)schemes in terms of several performance metrics i.e.,delay,jitter,throughput,load balancing,scalability and CPU(central processing unit)utilization.展开更多
By decoupling control plane and data plane,Software-Defined Networking(SDN) approach simplifies network management and speeds up network innovations.These benefits have led not only to prototypes,but also real SDN dep...By decoupling control plane and data plane,Software-Defined Networking(SDN) approach simplifies network management and speeds up network innovations.These benefits have led not only to prototypes,but also real SDN deployments.For wide-area SDN deployments,multiple controllers are often required,and the placement of these controllers becomes a particularly important task in the SDN context.This paper studies the problem of placing controllers in SDNs,so as to maximize the reliability of SDN control networks.We present a novel metric,called expected percentage of control path loss,to characterize the reliability of SDN control networks.We formulate the reliability-aware control placement problem,prove its NP-hardness,and examine several placement algorithms that can solve this problem.Through extensive simulations using real topologies,we show how the number of controllers and their placement influence the reliability of SDN control networks.Besides,we also found that,through strategic controller placement,the reliability of SDN control networks can be significantly improved without introducing unacceptable switch-to-controller latencies.展开更多
The emergence of a new network architecture,known as Software Defined Networking(SDN),in the last two decades has overcome some drawbacks of traditional networks in terms of performance,scalability,reliability,securit...The emergence of a new network architecture,known as Software Defined Networking(SDN),in the last two decades has overcome some drawbacks of traditional networks in terms of performance,scalability,reliability,security,and network management.However,the SDN is vulnerable to security threats that target its controller,such as low-rate Distributed Denial of Service(DDoS)attacks,The low-rate DDoS attack is one of the most prevalent attacks that poses a severe threat to SDN network security because the controller is a vital architecture component.Therefore,there is an urgent need to propose a detection approach for this type of attack with a high detection rate and low false-positive rates.Thus,this paper proposes an approach to detect low-rate DDoS attacks on the SDN controller by adapting a dynamic threshold.The proposed approach has been evaluated using four simulation scenarios covering a combination of low-rate DDoS attacks against the SDN controller involving(i)a single host attack targeting a single victim;(ii)a single host attack targeting multiple victims;(iii)multiple hosts attack targeting a single victim;and(iv)multiple hosts attack targeting multiple victims.The proposed approach’s average detection rates are 96.65%,91.83%,96.17%,and 95.33%for the above scenarios,respectively;and its average false-positive rates are 3.33%,8.17%,3.83%,and 4.67%for similar scenarios,respectively.The comparison between the proposed approach and two existing approaches showed that it outperformed them in both categories.展开更多
Controller placement problem(CPP)is a critical issue in software defined wireless networks(SDWN).Due to the limited power of wireless devices,CPP is facing the challenge of energy efficiency in SDWN.Nevertheless,the r...Controller placement problem(CPP)is a critical issue in software defined wireless networks(SDWN).Due to the limited power of wireless devices,CPP is facing the challenge of energy efficiency in SDWN.Nevertheless,the related research on CPP in SDWN hasn’t modeled the energy consumption of controllers so far.To prolong the lifetime of SDWN and improve the practicability of research,we rebuilt a CPP model considering the minimal transmitted power of controllers.An adaptive controller placement algorithm(ACPA)is proposed with the following two stages.First,data field method is adopted to determine sub-networks for different network topologies.Second,for each sub-network we adopt an exhaustive method to find the optimal location which meets the minimal average transmitted power to place controller.Compared with the other algorithms,the effectiveness and efficiency of the proposed scheme are validated through simulation.展开更多
The control and data planes are decoupled in software-defined networking(SDN),which enables both planes to evolve independently,and brings about many advantages such as high flexibility,programmability,and rapid imple...The control and data planes are decoupled in software-defined networking(SDN),which enables both planes to evolve independently,and brings about many advantages such as high flexibility,programmability,and rapid implementation of new network protocols.However,in order to improve the scalability of the control plane at present,some control functionalities are added to the data plane,which is probably to impact on the generality of the data plane.The key challenge of adding control functionalities to the data plane is to strike a careful balance between the generality of the data plane and the scalability of the control plane.We propose some basic principles that both control and data planes should comply with,based on the evolutionary trend of SDN.Moreover,we take two approaches for reference according to the principles,viewed from the control messages in OpenFlow-based SDN.Our evaluations demonstrate that the approaches can maintain the generality of the data plane and improve the scalability of the control plane.展开更多
To improve the reusable and configurable ability of computer numerical control ( CNC ) software, a new method to construct reusable model of CNC software with object-oriented (OO) technology is proposed. Based on anal...To improve the reusable and configurable ability of computer numerical control ( CNC ) software, a new method to construct reusable model of CNC software with object-oriented (OO) technology is proposed. Based on analyzing function of CNC software, the article presents how to construct a general class library of CNC software with OO technology. Most function modules of CNC software can he reused because of inheritable capability of classes. Besides, the article analyzes the object relational model in request/report mode, and multitask concurrent management model, which can he applied on double-CPU hardware platform and Windows 95/NT environment. Finally, the method has been successfully applied on a turning CNC system and a milling CNC system, and some function modules have been reused.展开更多
Many industrial companies and researchers are looking for more efficient model driven engineering approaches (MDE) in software engineering of manufacturing automation systems (MS) especially for logic control programm...Many industrial companies and researchers are looking for more efficient model driven engineering approaches (MDE) in software engineering of manufacturing automation systems (MS) especially for logic control programming, but are uncertain about the applicability and effort needed to implement those approaches in comparison to classical Programmable Logic Controller?(PLC) programming with IEC 61131-3. The paper summarizes results of usability experiments evaluating UML and SysML as software engineering notations for a MDE applied in the domain of manufacturing systems. Modeling MS needs to cover the domain specific characteristics,?i.e.?hybrid process, real time requirements and communication requirements. In addition the paper presents factors, constraint and practical experience for the development of further usability experiments. The paper gives examples of notational expressiveness and weaknesses of UML and SysML. The appendix delivers detailed master models, representing the correct best suited model, and evaluation schemes of the experiment, which is helpful if setting up own empirical experiments.展开更多
Supervisory control is a very popular paradigm for computer-controlled systems. Knowledge and tracking the control effect of every control operation is crucial to the control tasks. In the paper, we present a message-...Supervisory control is a very popular paradigm for computer-controlled systems. Knowledge and tracking the control effect of every control operation is crucial to the control tasks. In the paper, we present a message-array-based mechanism to track control effects in supervisory control software. A novel data type, message array, is designed to efficiently support this tracking mechanism. The operation algorithms, adding algorithm (AA), removing algorithm (RA), and scheduler algorithm (SA) are proposed to operate the tracking messages in message array, which forms the special first input X output (FIXO) strategy of message array. Automatically tracking, recording, and rolling back are the characteristics of our tracking mechanism. We implement this messagearray-based mechanism on the famous human machine interface (HMI) software platform-proficy iFix, and construct experiments to evaluate the performance of the mechanism in various cases. The results show our mechanism can be well satisfied with supervisory control software.展开更多
基金supported by UniversitiKebangsaan Malaysia,under Dana Impak Perdana 2.0.(Ref:DIP–2022–020).
文摘Software Defined Networking(SDN)is programmable by separation of forwarding control through the centralization of the controller.The controller plays the role of the‘brain’that dictates the intelligent part of SDN technology.Various versions of SDN controllers exist as a response to the diverse demands and functions expected of them.There are several SDN controllers available in the open market besides a large number of commercial controllers;some are developed tomeet carrier-grade service levels and one of the recent trends in open-source SDN controllers is the Open Network Operating System(ONOS).This paper presents a comparative study between open source SDN controllers,which are known as Network Controller Platform(NOX),Python-based Network Controller(POX),component-based SDN framework(Ryu),Java-based OpenFlow controller(Floodlight),OpenDayLight(ODL)and ONOS.The discussion is further extended into ONOS architecture,as well as,the evolution of ONOS controllers.This article will review use cases based on ONOS controllers in several application deployments.Moreover,the opportunities and challenges of open source SDN controllers will be discussed,exploring carriergrade ONOS for future real-world deployments,ONOS unique features and identifying the suitable choice of SDN controller for service providers.In addition,we attempt to provide answers to several critical questions relating to the implications of the open-source nature of SDN controllers regarding vendor lock-in,interoperability,and standards compliance,Similarly,real-world use cases of organizations using open-source SDN are highlighted and how the open-source community contributes to the development of SDN controllers.Furthermore,challenges faced by open-source projects,and considerations when choosing an open-source SDN controller are underscored.Then the role of Artificial Intelligence(AI)and Machine Learning(ML)in the evolution of open-source SDN controllers in light of recent research is indicated.In addition,the challenges and limitations associated with deploying open-source SDN controllers in production networks,how can they be mitigated,and finally how opensource SDN controllers handle network security and ensure that network configurations and policies are robust and resilient are presented.Potential opportunities and challenges for future Open SDN deployment are outlined to conclude the article.
基金National Natural Science Foundation of China(32201491)Young Elite Scientists Sponsorship Program by CAST(2023QNRC001)The authors extend their appreciation to the Deanship of Scientific Research at Northern Border University,Arar,KSA for funding this research work through the project number“NBU-FPEJ-2024-1101-02”.
文摘Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass materials.These materials offer numerous advantages such as being lightweight,porous,and hierarchical.Due to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EMI shielding materials.Despite concerted efforts on the EMI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EMI shielding materials.In particular,a more comprehensive study and summary of the factors influencing biomass EMI shielding materials including the pore structure adjustment,preparation process,and micro-control would be valuable.The preparation methods and characteristics of wood,bamboo,cellulose and lignin in EMI shielding field are critically discussed in this paper,and similar biomass EMI materials are summarized and analyzed.The composite methods and fillers of various biomass materials were reviewed.this paper also highlights the mechanism of EMI shielding as well as existing prospects and challenges for development trends in this field.
基金supported by the Fundamental Research Funds for Central Public Welfare Research Institute,No.2020CZ-5(to WS and GS)the National Natural Science Foundation of China,No.31970970(to JSR)Fundamental Research Funds for the Central Universities,No.YWF-23-YG-QB-010(to JSR)。
文摘Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury level.However,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface electromyography.In this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord injury.Eleven patients with chronic complete thoracic spinal cord injury were recruited.Surface electromyography data from eight major leg muscles were acquired and compared before and after the passive activity protocol.The results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of activation.Although the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically significant.These findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.
基金supported by the Natural Science Foundation of Shandong Province,No.ZR2023MC168the National Natural Science Foundation of China,No.31670989the Key R&D Program of Shandong Province,No.2019GSF107037(all to CS).
文摘Vascular endothelial growth factor and its mimic peptide KLTWQELYQLKYKGI(QK)are widely used as the most potent angiogenic factors for the treatment of multiple ischemic diseases.However,conventional topical drug delivery often results in a burst release of the drug,leading to transient retention(inefficacy)and undesirable diffusion(toxicity)in vivo.Therefore,a drug delivery system that responds to changes in the microenvironment of tissue regeneration and controls vascular endothelial growth factor release is crucial to improve the treatment of ischemic stroke.Matrix metalloproteinase-2(MMP-2)is gradually upregulated after cerebral ischemia.Herein,vascular endothelial growth factor mimic peptide QK was self-assembled with MMP-2-cleaved peptide PLGLAG(TIMP)and customizable peptide amphiphilic(PA)molecules to construct nanofiber hydrogel PA-TIMP-QK.PA-TIMP-QK was found to control the delivery of QK by MMP-2 upregulation after cerebral ischemia/reperfusion and had a similar biological activity with vascular endothelial growth factor in vitro.The results indicated that PA-TIMP-QK promoted neuronal survival,restored local blood circulation,reduced blood-brain barrier permeability,and restored motor function.These findings suggest that the self-assembling nanofiber hydrogel PA-TIMP-QK may provide an intelligent drug delivery system that responds to the microenvironment and promotes regeneration and repair after cerebral ischemia/reperfusion injury.
基金Supported by the Inner Mongolia Autonomous Region s Key Research and Achievement Transformation plan (2023YFHH0093).
文摘The quality control chart of fructo-oligosaccharides in milk powder was established to determine whether the detection process and results are in control state.The content of fructo-oligosaccharides in milk powder control samples was determined by ion chromatography,and the quality control chart of fructo-oligosaccharides was established to analyze the controlled state.The results indicate that the median of the quality control chart is 1613.14 mg/100 g,and the standard deviation is 85.57 mg/100 g.The new quality control points were evaluated and analyzed,and the precision changed,but the mean value did not change.Further F test was conducted to determine that the precision did not change significantly,indicating that the test was in a statistical control state,and the detection process,method and results were controlled.
基金National Natural ScienceFoundation of China (grant number: 81973696).
文摘Gualou-Xiebai-Banxia Decoction(GXBD)is a traditional Chinese herbal formula including four traditional Chinese medicines:Gualou(Trichosanthis Fructus,TF),Xiebai(Allii Macrostemonis Bulbus,AMB),Banxia(Pinelliae Rhizoma,PR)and yellow wine.It is a classical therapy for chest stuffiness and pain syndrome and is widely used in the clinical treatment of coronary heart disease.It also shows significant therapeutic effects on pulmonary heart disease,hyperlipidemia,and arrhythmia.This study conducted a literature review and collected information on GXBD from databases such as PubMed,Web of Science,China National Knowledge Infrastructure,and ScienceDirect.The result indicated that the main active ingredients of GXBD are steroids,flavonoids,terpenoids,alkaloids,amino acids,and organic acids.Trigonelline,macrostemonoside and cucurbitacin B can provide reference for its quality control.GXBD may exert therapeutic effects on coronary heart disease through AMPK,PI3K-AKT,oxLDL,VEGF,and NF-κB signal pathways.This review provides a comprehensive analysis and summary of the chemical composition and in vivo metabolism of three traditional Chinese medicines(TF,AMB,and PR),along with an evaluation of the chemical composition,quality control,pharmacological effects,and clinical application of GXBD.Based on these,areas requiring further research on GXBD have been proposed to provide a reference for its further development and new drug research.
基金Supported by Henan Province Key Research and Development Program,No.231111311000Henan Provincial Science and Technology Research Project,No.232102310411+2 种基金Henan Province Medical Science and Technology Key Project,No.LHGJ20220566 and No.LHGJ20240365Henan Province Medical Education Research Project,No.WJLX2023079Zhengzhou Medical and Health Technology Innovation Guidance Program,No.2024YLZDJH022.
文摘This study highlights the importance of identifying and addressing risk factors associated with wound complications following transtibial amputation in diabetic patients.These amputations,often necessitated by severe diabetic foot ulcers,carry significant risks of postoperative complications such as infection and delayed wound healing.Elevated hemoglobin A1c levels,indicative of poor glycemic control,and a history of kidney transplantation,due to required immunosuppressive therapy,are key factors influencing these outcomes.This paper emphasizes the need for enhanced glycemic management and personalized postoperative care,particularly for immunocompromised individuals,to minimize complications and improve patient prognosis.Future research should focus on prospective studies to validate targeted interventions and optimize care strategies,ultimately aiming to reduce the healthcare burden associated with diabetic foot complications.
基金supported in part by NSFC project(61871056)Young Elite Scientists Sponsorship Program by CAST(2018QNRC001)+1 种基金Fundamental Research Funds for the Central Universities(2018XKJC06)Open Fund of SKL of IPOC(BUPT)(IPOC2018A001)
文摘Software defined optical networking(SDON)is a critical technology for the next generation network with the advantages of programmable control and etc.As one of the key issues of SDON,the security of control plane has also received extensive attention,especially in certain network scenarios with high security requirement.Due to the existence of vulnerabilities and heavy overhead,the existing firewalls and distributed control technologies cannot solve the control plane security problem well.In this paper,we propose a distributed control architecture for SDON using the blockchain technique(BlockCtrl).The proposed BlockCtrl model introduces the advantages of blockchain into SDON to achieve a high-efficiency fault tolerant control.We have evaluated the performance of our proposed architecture and compared it to the existing models with respect to various metrics including processing rate,recovery latency and etc.The numerical results show that the BlockCtrl is capable of attacks detection and fault tolerant control in SDON with high performance on resource utilization and service correlation.
文摘The previous operation of the ZLS-Burris gravity meter using a PDA already provides a significant improvement of the operation of a metal spring gravity meter. But in the practical field work the observer usually wishes more information about the measurement and the collected data. This situation sug- gested an improvement of the software and computer hardware. The goal was to develop a small useful PC tool that eliminates these deficits. However, it resulted in a very extensive application software, which was developed during 2011-2015. Along the way, some unwanted effects of the original control circuit were detected. Therefore as a last step a complete new control circuit for the feedback system was developed. This new circuit is fast and smooth and without resonance effects to the system. The algorithm parameters can be specifically adapted to the specific gravity meter. The software has a security system that ensures the user, depending on his level of knowledge, a limited access to the software options. Furthermore, a customer project management system is integrated. The observer, the gravity meters, the projects and maps can be assigned. Several ZLS Burris gravity meters can be managed. A large station data management is integrated. Every station has up to more than twenty parameters, such as the mandatory coordinates or supplementary pictures of the station. External storage and documentation of the measurements are possible with extra modules. In addition the maintenance of the gravity meter system is significantly improved. The motor control of the early ZLS Burris gravity meter is also improved. The complete rotation is displayed on the screen. Finally, two survey examples show the advantages of the software related to the accuracy and the time needed for a measurement.
基金supported by the Fundamental Research Funds for the Central Universities(4007019109)(RECON-STRUCT)the Special Guiding Funds for Double First-class(4007019201)the Joint TU Delft-CSSC Project ‘Multi-agent Coordination with Networked Constraints’(MULTI-COORD)
文摘This paper discusses the design and software-in-theloop implementation of adaptive formation controllers for fixedwing unmanned aerial vehicles(UAVs) with parametric uncertainty in their structure, namely uncertain mass and inertia. In fact, when aiming at autonomous flight, such parameters cannot assumed to be known as they might vary during the mission(e.g.depending on the payload). Modeling and autopilot design for such autonomous fixed-wing UAVs are presented. The modeling is implemented in Matlab, while the autopilot is based on ArduPilot, a popular open-source autopilot suite. Specifically, the ArduP ilot functionalities are emulated in Matlab according to the Ardupilot documentation and code, which allows us to perform software-in-the-loop simulations of teams of UAVs embedded with actual autopilot protocols. An overview of realtime path planning, trajectory tracking and formation control resulting from the proposed platform is given. The software-inthe-loop simulations show the capability of achieving different UAV formations while handling uncertain mass and inertia.
基金Supported by National High Technology Development plan(Item No.:2001AA412250)and Shanghai Science & Technology Development Project(Item No.:02FK04)
文摘A new method that designs and implements the component-based distributed & hierarchical flexible manufacturing control software is described with a component concept in this paper. The proposed method takes aim at improving the flexibility and reliability of the control system. On the basis of describing the concepts of component-based software and the distributed object technology, the architecture of the component-based software of the control system is suggested with the Common Object Request Broker Architecture (CORBA). And then, we propose a design method for component-based distributed & hierarchical flexible manufacturing control system. Finally, to verify the software design method, a prototype flexible manufacturing control system software has been implemented in Orbix 2.3c, VC + + 6. 0 and has been tested in connection with the physical flexible manufacturing shop at the WuXi Professional Institute.
基金the National High-tech R&D Program ("863" Program) of China,the National Science Foundation of China,National Science & Technology Pillar Program of China,the National Science Foundation of China,the Post-Doctoral Funding of China,Tsinghua-Huawei joint research project
文摘In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.In this paper,we develop a flexible dormant multi-controller model based on the centralized multi-controller architecture.The dormant multi-controller model allows part of controllers to enter the dormant state under light traffic condition for saving system cost.Meanwhile,through queueing analysis,various performance measures of the system can be obtained.Moreover,we analyze the real traffic of China Education Network and use the results as the parameters of computer simulation and verify the effects of parameters on the system characteristics.Finally,a total expected cost function is established,and genetic algorithm is employed to find the optimal values of various parameters to minimize system cost for the deployment decision making.
基金supported by the MSIT(Ministry of Science and ICT),Korea,under the ITRC(Information Technology Research Center)support program(IITP-2020-2018-0-01431)supervised by the IITP(Institute for Information&Communications Technology Planning&Evaluation).
文摘The controller is indispensable in software-defined networking(SDN).With several features,controllers monitor the network and respond promptly to dynamic changes.Their performance affects the quality-of-service(QoS)in SDN.Every controller supports a set of features.However,the support of the features may be more prominent in one controller.Moreover,a single controller leads to performance,single-point-of-failure(SPOF),and scalability problems.To overcome this,a controller with an optimum feature set must be available for SDN.Furthermore,a cluster of optimum feature set controllers will overcome an SPOF and improve the QoS in SDN.Herein,leveraging an analytical network process(ANP),we rank SDN controllers regarding their supporting features and create a hierarchical control plane based cluster(HCPC)of the highly ranked controller computed using the ANP,evaluating their performance for the OS3E topology.The results demonstrated in Mininet reveal that a HCPC environment with an optimum controller achieves an improved QoS.Moreover,the experimental results validated in Mininet show that our proposed approach surpasses the existing distributed controller clustering(DCC)schemes in terms of several performance metrics i.e.,delay,jitter,throughput,load balancing,scalability and CPU(central processing unit)utilization.
基金supported in part by the National High Technology Research and Development Program(863 Program)of China under Grant No.2011AA01A101the National High Technology Research and Development Program(863 Program)of China under Grant No.2013AA01330the National High Technology Research and Development Program(863 Program)of China under Grant No.2013AA013303
文摘By decoupling control plane and data plane,Software-Defined Networking(SDN) approach simplifies network management and speeds up network innovations.These benefits have led not only to prototypes,but also real SDN deployments.For wide-area SDN deployments,multiple controllers are often required,and the placement of these controllers becomes a particularly important task in the SDN context.This paper studies the problem of placing controllers in SDNs,so as to maximize the reliability of SDN control networks.We present a novel metric,called expected percentage of control path loss,to characterize the reliability of SDN control networks.We formulate the reliability-aware control placement problem,prove its NP-hardness,and examine several placement algorithms that can solve this problem.Through extensive simulations using real topologies,we show how the number of controllers and their placement influence the reliability of SDN control networks.Besides,we also found that,through strategic controller placement,the reliability of SDN control networks can be significantly improved without introducing unacceptable switch-to-controller latencies.
基金This work was supported by Universiti Sains Malaysia under external grant(Grant Number 304/PNAV/650958/U154).
文摘The emergence of a new network architecture,known as Software Defined Networking(SDN),in the last two decades has overcome some drawbacks of traditional networks in terms of performance,scalability,reliability,security,and network management.However,the SDN is vulnerable to security threats that target its controller,such as low-rate Distributed Denial of Service(DDoS)attacks,The low-rate DDoS attack is one of the most prevalent attacks that poses a severe threat to SDN network security because the controller is a vital architecture component.Therefore,there is an urgent need to propose a detection approach for this type of attack with a high detection rate and low false-positive rates.Thus,this paper proposes an approach to detect low-rate DDoS attacks on the SDN controller by adapting a dynamic threshold.The proposed approach has been evaluated using four simulation scenarios covering a combination of low-rate DDoS attacks against the SDN controller involving(i)a single host attack targeting a single victim;(ii)a single host attack targeting multiple victims;(iii)multiple hosts attack targeting a single victim;and(iv)multiple hosts attack targeting multiple victims.The proposed approach’s average detection rates are 96.65%,91.83%,96.17%,and 95.33%for the above scenarios,respectively;and its average false-positive rates are 3.33%,8.17%,3.83%,and 4.67%for similar scenarios,respectively.The comparison between the proposed approach and two existing approaches showed that it outperformed them in both categories.
基金supported by the Open Research Fund of Key Laboratory of Space Utilization,Chinese Academy of Sciences(No.LSU-KFJJ-2018-06)the International Research Cooperation Seed Fund of Beijing University of Technology(No.2018B41)
文摘Controller placement problem(CPP)is a critical issue in software defined wireless networks(SDWN).Due to the limited power of wireless devices,CPP is facing the challenge of energy efficiency in SDWN.Nevertheless,the related research on CPP in SDWN hasn’t modeled the energy consumption of controllers so far.To prolong the lifetime of SDWN and improve the practicability of research,we rebuilt a CPP model considering the minimal transmitted power of controllers.An adaptive controller placement algorithm(ACPA)is proposed with the following two stages.First,data field method is adopted to determine sub-networks for different network topologies.Second,for each sub-network we adopt an exhaustive method to find the optimal location which meets the minimal average transmitted power to place controller.Compared with the other algorithms,the effectiveness and efficiency of the proposed scheme are validated through simulation.
文摘The control and data planes are decoupled in software-defined networking(SDN),which enables both planes to evolve independently,and brings about many advantages such as high flexibility,programmability,and rapid implementation of new network protocols.However,in order to improve the scalability of the control plane at present,some control functionalities are added to the data plane,which is probably to impact on the generality of the data plane.The key challenge of adding control functionalities to the data plane is to strike a careful balance between the generality of the data plane and the scalability of the control plane.We propose some basic principles that both control and data planes should comply with,based on the evolutionary trend of SDN.Moreover,we take two approaches for reference according to the principles,viewed from the control messages in OpenFlow-based SDN.Our evaluations demonstrate that the approaches can maintain the generality of the data plane and improve the scalability of the control plane.
基金Supported by Science and Technology Development Foundation of Shanghai Science and Technology Committee(995107017)
文摘To improve the reusable and configurable ability of computer numerical control ( CNC ) software, a new method to construct reusable model of CNC software with object-oriented (OO) technology is proposed. Based on analyzing function of CNC software, the article presents how to construct a general class library of CNC software with OO technology. Most function modules of CNC software can he reused because of inheritable capability of classes. Besides, the article analyzes the object relational model in request/report mode, and multitask concurrent management model, which can he applied on double-CPU hardware platform and Windows 95/NT environment. Finally, the method has been successfully applied on a turning CNC system and a milling CNC system, and some function modules have been reused.
文摘Many industrial companies and researchers are looking for more efficient model driven engineering approaches (MDE) in software engineering of manufacturing automation systems (MS) especially for logic control programming, but are uncertain about the applicability and effort needed to implement those approaches in comparison to classical Programmable Logic Controller?(PLC) programming with IEC 61131-3. The paper summarizes results of usability experiments evaluating UML and SysML as software engineering notations for a MDE applied in the domain of manufacturing systems. Modeling MS needs to cover the domain specific characteristics,?i.e.?hybrid process, real time requirements and communication requirements. In addition the paper presents factors, constraint and practical experience for the development of further usability experiments. The paper gives examples of notational expressiveness and weaknesses of UML and SysML. The appendix delivers detailed master models, representing the correct best suited model, and evaluation schemes of the experiment, which is helpful if setting up own empirical experiments.
文摘Supervisory control is a very popular paradigm for computer-controlled systems. Knowledge and tracking the control effect of every control operation is crucial to the control tasks. In the paper, we present a message-array-based mechanism to track control effects in supervisory control software. A novel data type, message array, is designed to efficiently support this tracking mechanism. The operation algorithms, adding algorithm (AA), removing algorithm (RA), and scheduler algorithm (SA) are proposed to operate the tracking messages in message array, which forms the special first input X output (FIXO) strategy of message array. Automatically tracking, recording, and rolling back are the characteristics of our tracking mechanism. We implement this messagearray-based mechanism on the famous human machine interface (HMI) software platform-proficy iFix, and construct experiments to evaluate the performance of the mechanism in various cases. The results show our mechanism can be well satisfied with supervisory control software.