A software package to be used in high-speed oscilloscope-basedthree-dimensionalbunch-by-bunch charge and position measurement is presented.The software package takes the pick-up electrode signal waveform recorded by t...A software package to be used in high-speed oscilloscope-basedthree-dimensionalbunch-by-bunch charge and position measurement is presented.The software package takes the pick-up electrode signal waveform recorded by the high-speed oscilloscope as input,and it calculates and outputs the bunch-by-bunch charge and position.In addition to enabling a three-dimensional observation of the motion of each passing bunch on all beam position monitor pick-up electrodes,it offers many additional features such as injection analysis,bunch response function reconstruction,and turn-by-turn beam analysis.The software package has an easy-to-understand graphical user interface and convenient interactive operation,which has been verified on the Windows 10 system.展开更多
The magnetic resonance spectroscopy(MRS)results are greatly influenced by reconstruction of the spectrum and quantitative analysis.Because of this requirement a number of programs dedicated to MRS data analysis were d...The magnetic resonance spectroscopy(MRS)results are greatly influenced by reconstruction of the spectrum and quantitative analysis.Because of this requirement a number of programs dedicated to MRS data analysis were developed.The selection and use of appropriate software is crucial not only in clinical procedures,but also while carrying out scientific research.The choice of the software to suit the user's needs should be based on the analysis of the functionality of the program.It is particularly important from the user's viewpoint to identify what data can be loaded and processed in the program.The specific programs allow the user different degree of control over analysis parameters.Moreover,the programs for MRS data analysis differ in terms of the applied signal processing algorithms.The aim of this work,therefore,is to review available packages designed for MRS data analysis,taking into account their capabilities and limitations.展开更多
The weldabiUty of some material is analyzed with simple calculating program in this paper, and weldability testing data are shared through database system. The welding procedures are designed with help of expert syste...The weldabiUty of some material is analyzed with simple calculating program in this paper, and weldability testing data are shared through database system. The welding procedures are designed with help of expert systems, and the knowledge is shared among welding engineers. Not only the preparing progress of the welding documents is completed with database systems but also the complex decision on the necessity of the qualification test according to the present procedure qualification records (PQRs) and manufacture codes is made. Moreover, the artificial neural network (ANN) technique is proven to be one of the effective ways to predict mechanical properties of welded joints when there are enough tested data to train the models. Finally, the achievements in modeling microstructure of welded joints are introduced, especially in solid transformation and grain growth in both heat-affected zone (HAZ) and welded molten pool.展开更多
In this paper we study how organizational learning impacts organizational behavior, and how vendor support quality enhances product adoption and usage behavior. These constructs were verified using Application Softwar...In this paper we study how organizational learning impacts organizational behavior, and how vendor support quality enhances product adoption and usage behavior. These constructs were verified using Application Software Packages (ASP) - a prewritten, precoded, commercially available set of programs that eliminates the need for individuals or organizations to write their own software programs for certain functions. The relationship between ASP usage, usage outcomes and use processes were also investigated. Two hundred and ninety-five Chinese, Indian, and Malay entrepreneurships were studied. It was found that usage outcome strongly determines usage, while use process has only an indirect relationship (via outcome) on usage. The impact of organizational learning and vendor service quality on usage, usage outcome, and use process were robust. Theoretical and practical implications of the research are discussed.展开更多
This paper introduces a software specially in calculating the contribution rate of machanization in agriculture by usng economy math method,computer technology and Visual Basic 6.0 version.The software package has fri...This paper introduces a software specially in calculating the contribution rate of machanization in agriculture by usng economy math method,computer technology and Visual Basic 6.0 version.The software package has friendly interface,simple operating way and accurate,feasible calculating method.It greatly changes the condition in the past which had considerable lots of data and miscellaneous and trivial methods,which were even hard to seek answer.So it has very high practicl value.展开更多
Researchers must understand that naively relying on the reliability of statistical software packages may result in suboptimal, biased, or erroneous results, which affects applied economic theory and the conclusions an...Researchers must understand that naively relying on the reliability of statistical software packages may result in suboptimal, biased, or erroneous results, which affects applied economic theory and the conclusions and policy recommendations drawn from it. To create confidence in a result, several software packages should be applied to the same estimation problem. This study examines the results of three software packages (EViews, R, and Stata) in the analysis of time-series econometric data. The time-series data analysis which presents the determinants of macroeconomic growth of Sri Lanka from 1978 to 2020 has been used. The study focuses on testing for stationarity, cointegration, and significant relationships among the variables. The Augmented Dickey-Fuller and Phillips Perron tests were employed in this study to test for stationarity, while the Johansen cointegration test was utilized to test for cointegration. The study employs the vector error correction model to assess the short-run and long-term dynamics of the variables in an attempt to determine the relationship between them. Finally, the Granger Causality test is employed in order to examine the linear causation between the concerned variables. The study revealed that the results produced by three software packages for the same dataset and the same lag order vary significantly. This implies that time series econometrics results are sensitive to the software that is used by the researchers while providing different policy implications even for the same dataset. The present study highlights the necessity of further analysis to investigate the impact of software packages in time series analysis of economic scenarios.展开更多
Metallic elements have various origins: natural and anthropogenic sources as geochemical, marine and atmospheric sources resulting from the fallout of pollutants emitted or dust raised and which are transported by wat...Metallic elements have various origins: natural and anthropogenic sources as geochemical, marine and atmospheric sources resulting from the fallout of pollutants emitted or dust raised and which are transported by water and air currents. Thus marine, brackish and fresh continental waters may have high metal concentrations. In addition, some essential metals can become toxic above certain concentration values in aquatic environments. The aquatic ecosystems of Cotonou channel and lake Nokoué receive the pollutants charges from the town cities of Cotonou, Abomey-Calavi and town hall of So Ava. The aim of this study is to analyze waters from Eighteen (18) stations identified in the two ecosystems (nine by ecosystem). The concentrations of magnesium (Mg), calcium (Ca), vanadium (V), chromium (Cr), manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), selenium (Se), cadmium (Cd), beryllium (Be), aluminum (Al), strontium (Sr), molybdenum (Mo), silver (Ag), tin (Sn), barium (Ba), platinum (Pt), mercury (Hg), thallium (Tl), lead (Pb), thorium (Th) and uranium (U) were measured after acid digestion of the water samples using the inductively coupled plasma source mass spectrometer (ICP-MS). The results of the analyses indicate an unequal distribution of metals in the different ecosystems. However, atypical concentrations were observed at some stations of the lake and the channel. Magnesium, calcium and manganese have very high values in Lake Nokoué respectively at Ganvié market station GAN_M (2990 ± 105 mg/L), Ganvié center, station GAN_C (4991 ± 177 mg/L) and Lake middle station MLak4 (10662 ± 17.03 μg/L). On the other hand, iron, aluminum and strontium have very high concentrations in the Cotonou Channel respectively at Agbato station AGB (5236 ± 103 and 8289 ± 519 μg/L) and at the estuary station EST (6118 ± 68 μg/L). The concentrations were compared to wells and cborehole waters in sixth neighborhood of Cotonou. We have used statistical analyzers such as MANOVA which have made it possible to classify the waters and metals in the ecosystems studied compared to groundwater and Well water waters. We use hierarchical clustering on principal components to identify similarities between stations based on metal concentration with R software packages “FactoMineR” and “factoextra”. In general, we can conclude that most of the metals have an anthropogenic source except strontium and major elements (Ca and Mg) which could respectively provide from marine waters and geochemical sources.展开更多
Diffusion couples,WC/Co-1at.%C,V8C7/Co,and WC/Co-0.3wt.%V8C7 were constructed and annealed at temperatures ranging from 1100 to 1300℃. The concentration profile of V and W atoms in these couples were measured by EPMA...Diffusion couples,WC/Co-1at.%C,V8C7/Co,and WC/Co-0.3wt.%V8C7 were constructed and annealed at temperatures ranging from 1100 to 1300℃. The concentration profile of V and W atoms in these couples were measured by EPMA. Aided by Thermo-calc & DICTRA software package,the concentration profiles of W and V in established diffusion couples were calculated by the moving boundary model according to revised dynamic parameters and MOB database,respectively. Then the concentration profile of W in Co binder during sintering WC-Co cemented carbide was simulated by the Cell model. It can provide reference for composition and sintering process design of cemented carbides with high performance. Meanwhile,the validity of revised dynamic parameters of the W-C-Co-V system is verified by the comparison of experimental and simulated results.展开更多
AISI H13 hot work tool steel is widely used for hot forging, hot-extrusion and die-casting because of its high temperature strength, impact toughness, heat checking resistance and wear resistance, etc. The thermally i...AISI H13 hot work tool steel is widely used for hot forging, hot-extrusion and die-casting because of its high temperature strength, impact toughness, heat checking resistance and wear resistance, etc. The thermally induced surface damage, i. e., thermal fatigne,is believed to be controlled by the magnitude of the imposed cyclic strain. The thermal fatigue on the surface of hot working die, which is responsible to the initiation of the cracks, is reported to result in more than 80 % of the failure of dies.展开更多
Thermo-Calc software package (TCP+DICTRA) was used to simulate the carbide transformation process in die steel for plastic. Combined with TEM analysis, the calculated result confirms that the carbide in equilibrium st...Thermo-Calc software package (TCP+DICTRA) was used to simulate the carbide transformation process in die steel for plastic. Combined with TEM analysis, the calculated result confirms that the carbide in equilibrium state is M_7C_3 carbide. The dissolution of M_7C_3 carbide in steel is predicted by DICTRA program. It was shown that the temperature remarkably affects the dissolution process of M_7C_3 carbide, but the influence of alloy elements such as manganese and molybdenum can be neglected in this steel.展开更多
Core axial power distribution is an essential topic in pressurized water reactor(PWR)reactivity control.Traditional PWRs limit stability against axial core power oscillations at a high-cycle burnup.Because the‘‘came...Core axial power distribution is an essential topic in pressurized water reactor(PWR)reactivity control.Traditional PWRs limit stability against axial core power oscillations at a high-cycle burnup.Because the‘‘camel’’peak power shape typically occurs with increasing depletion,the approaches used for the axial power control deserve special attention.This study aims to investigate the performance of different gadolinium rod design schemes in core axial power control during power operation based on the reactivity balance strategy,and to propose new multiconcentration gadolinium rod design schemes.In the new design schemes,low-concentration gadolinium pellets are filled in the axial hump part of the gadolinium rod,and high-concentration gadolinium pellets are filled in the other parts.The impact of different gadolinium rod design schemes on the main core characteristics was evaluated using the nuclear design code package PCM developed by CGN.The results show that the new gadolinium rod design significantly impacts the core axial power shape.The new design schemes can efficiently improve the core axial power distribution along the entire cycle by reducing the core axial power peak at the end of a cycle,enhancing the reactor operation stability,and achieving a better core safety margin,revealing a sizeable potential application.展开更多
Magnetics,ferroelectrics,and multiferroics have attracted great attentions because they are not only extremely im-portant for investigating fundamental physics,but also have important applications in information techn...Magnetics,ferroelectrics,and multiferroics have attracted great attentions because they are not only extremely im-portant for investigating fundamental physics,but also have important applications in information technology.Here,recent computational studies on magnetism and ferroelectricity are reviewed.We first give a brief introduction to magnets,fer-roelectrics,and multiferroics.Then,theoretical models and corresponding computational methods for investigating these materials are presented.In particular,a new method for computing the linear magnetoelectric coupling tensor without applying an external field in the first principle calculations is proposed for the first time.The functionalities of our home-made Property Analysis and Simulation Package for materials(PASP)and its applications in the field of magnetism and ferroelectricity are discussed.Finally,we summarize this review and give a perspective on possible directions of future computational studies on magnetism and ferroelectricity.展开更多
Objective: To determine the bioinformatical characteristics of differential gene expression in patients with chronic superficial gastritis (CSG) with the Pi-deficiency syndrome (PDS) and those of the non- Pi-defi...Objective: To determine the bioinformatical characteristics of differential gene expression in patients with chronic superficial gastritis (CSG) with the Pi-deficiency syndrome (PDS) and those of the non- Pi-deficiency syndrome (non-PDS), i.e. patients of CSG with Pi (脾)-Wei (胃) dampnese-heat syndrome and healthy persons. Methods: With the BRB-Array Tools software package, original data collection and bioinformatic analysis of gene arrays were conducted in 6 CSG patients of PDS (CSG-PDS), 6 CSG patients of non-PDS (CSG-nPDS), and 6 healthy volunteers (Normal). Results: Compared with non-PDS, the gene expressions in PDS with regards to protein synthesis, energy metabolism, immune reaction and ionic transport tended to be down-regulated, while those concerning secretion, cytoskeleton and ubiquitinization were up-regulated dominantly. Conclusions: The two kinds of samples, CSG-PDS/Normal and CSG-PDS/CSG-nPDS, have their respective gene expression profiles with different characteristics. Gene expression profile has certain referential significance in syndrome classification.展开更多
In this paper we present a software package based on modern information technologies that allows rapid analysis and visualization of the properties of complex plasmas.The properties of plasma are simulated by two mean...In this paper we present a software package based on modern information technologies that allows rapid analysis and visualization of the properties of complex plasmas.The properties of plasma are simulated by two means.First of all,we have applied the molecular dynamics simulation method which numerically solves the equations of motions for plasma particles.Secondly,we calculate microscopic properties of plasma by using the Boltzmann equation with additional relations,initial and boundary conditions.展开更多
We introduce the concept of Canonical Workflow Building Blocks(CWBB),a methodology of describing and wrapping computational tools,in order for them to be utilised in a reproducible manner from multiple workflow langua...We introduce the concept of Canonical Workflow Building Blocks(CWBB),a methodology of describing and wrapping computational tools,in order for them to be utilised in a reproducible manner from multiple workflow languages and execution platforms.The concept is implemented and demonstrated with the BioExcel Building Blocks library(BioBB),a collection of tool wrappers in the field of computational biomolecular simulation.Interoperability across different workflow languages is showcased through a protein Molecular Dynamics setup transversal workflow,built using this library and run with 5 different Workflow Manager Systems(WfMS).We argue such practice is a necessary requirement for FAIR Computational Workflows and an element of Canonical Workflow Frameworks for Research(CWFR)in order to improve widespread adoption and reuse of computational methods across workflow language barriers.展开更多
基金supported by the Ten Thousand Talent Program and National Natural Science Foundation of China(No.11575282)the Ten Thousand Talent Program and Chinese Academy of Sciences Key Technology Talent Program。
文摘A software package to be used in high-speed oscilloscope-basedthree-dimensionalbunch-by-bunch charge and position measurement is presented.The software package takes the pick-up electrode signal waveform recorded by the high-speed oscilloscope as input,and it calculates and outputs the bunch-by-bunch charge and position.In addition to enabling a three-dimensional observation of the motion of each passing bunch on all beam position monitor pick-up electrodes,it offers many additional features such as injection analysis,bunch response function reconstruction,and turn-by-turn beam analysis.The software package has an easy-to-understand graphical user interface and convenient interactive operation,which has been verified on the Windows 10 system.
文摘The magnetic resonance spectroscopy(MRS)results are greatly influenced by reconstruction of the spectrum and quantitative analysis.Because of this requirement a number of programs dedicated to MRS data analysis were developed.The selection and use of appropriate software is crucial not only in clinical procedures,but also while carrying out scientific research.The choice of the software to suit the user's needs should be based on the analysis of the functionality of the program.It is particularly important from the user's viewpoint to identify what data can be loaded and processed in the program.The specific programs allow the user different degree of control over analysis parameters.Moreover,the programs for MRS data analysis differ in terms of the applied signal processing algorithms.The aim of this work,therefore,is to review available packages designed for MRS data analysis,taking into account their capabilities and limitations.
基金Acknowledgements Financial support by the National Natural Science Foundation of China under Grant No. 50775112 is gratefully acknowledged.
文摘The weldabiUty of some material is analyzed with simple calculating program in this paper, and weldability testing data are shared through database system. The welding procedures are designed with help of expert systems, and the knowledge is shared among welding engineers. Not only the preparing progress of the welding documents is completed with database systems but also the complex decision on the necessity of the qualification test according to the present procedure qualification records (PQRs) and manufacture codes is made. Moreover, the artificial neural network (ANN) technique is proven to be one of the effective ways to predict mechanical properties of welded joints when there are enough tested data to train the models. Finally, the achievements in modeling microstructure of welded joints are introduced, especially in solid transformation and grain growth in both heat-affected zone (HAZ) and welded molten pool.
文摘In this paper we study how organizational learning impacts organizational behavior, and how vendor support quality enhances product adoption and usage behavior. These constructs were verified using Application Software Packages (ASP) - a prewritten, precoded, commercially available set of programs that eliminates the need for individuals or organizations to write their own software programs for certain functions. The relationship between ASP usage, usage outcomes and use processes were also investigated. Two hundred and ninety-five Chinese, Indian, and Malay entrepreneurships were studied. It was found that usage outcome strongly determines usage, while use process has only an indirect relationship (via outcome) on usage. The impact of organizational learning and vendor service quality on usage, usage outcome, and use process were robust. Theoretical and practical implications of the research are discussed.
文摘This paper introduces a software specially in calculating the contribution rate of machanization in agriculture by usng economy math method,computer technology and Visual Basic 6.0 version.The software package has friendly interface,simple operating way and accurate,feasible calculating method.It greatly changes the condition in the past which had considerable lots of data and miscellaneous and trivial methods,which were even hard to seek answer.So it has very high practicl value.
文摘Researchers must understand that naively relying on the reliability of statistical software packages may result in suboptimal, biased, or erroneous results, which affects applied economic theory and the conclusions and policy recommendations drawn from it. To create confidence in a result, several software packages should be applied to the same estimation problem. This study examines the results of three software packages (EViews, R, and Stata) in the analysis of time-series econometric data. The time-series data analysis which presents the determinants of macroeconomic growth of Sri Lanka from 1978 to 2020 has been used. The study focuses on testing for stationarity, cointegration, and significant relationships among the variables. The Augmented Dickey-Fuller and Phillips Perron tests were employed in this study to test for stationarity, while the Johansen cointegration test was utilized to test for cointegration. The study employs the vector error correction model to assess the short-run and long-term dynamics of the variables in an attempt to determine the relationship between them. Finally, the Granger Causality test is employed in order to examine the linear causation between the concerned variables. The study revealed that the results produced by three software packages for the same dataset and the same lag order vary significantly. This implies that time series econometrics results are sensitive to the software that is used by the researchers while providing different policy implications even for the same dataset. The present study highlights the necessity of further analysis to investigate the impact of software packages in time series analysis of economic scenarios.
文摘Metallic elements have various origins: natural and anthropogenic sources as geochemical, marine and atmospheric sources resulting from the fallout of pollutants emitted or dust raised and which are transported by water and air currents. Thus marine, brackish and fresh continental waters may have high metal concentrations. In addition, some essential metals can become toxic above certain concentration values in aquatic environments. The aquatic ecosystems of Cotonou channel and lake Nokoué receive the pollutants charges from the town cities of Cotonou, Abomey-Calavi and town hall of So Ava. The aim of this study is to analyze waters from Eighteen (18) stations identified in the two ecosystems (nine by ecosystem). The concentrations of magnesium (Mg), calcium (Ca), vanadium (V), chromium (Cr), manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), selenium (Se), cadmium (Cd), beryllium (Be), aluminum (Al), strontium (Sr), molybdenum (Mo), silver (Ag), tin (Sn), barium (Ba), platinum (Pt), mercury (Hg), thallium (Tl), lead (Pb), thorium (Th) and uranium (U) were measured after acid digestion of the water samples using the inductively coupled plasma source mass spectrometer (ICP-MS). The results of the analyses indicate an unequal distribution of metals in the different ecosystems. However, atypical concentrations were observed at some stations of the lake and the channel. Magnesium, calcium and manganese have very high values in Lake Nokoué respectively at Ganvié market station GAN_M (2990 ± 105 mg/L), Ganvié center, station GAN_C (4991 ± 177 mg/L) and Lake middle station MLak4 (10662 ± 17.03 μg/L). On the other hand, iron, aluminum and strontium have very high concentrations in the Cotonou Channel respectively at Agbato station AGB (5236 ± 103 and 8289 ± 519 μg/L) and at the estuary station EST (6118 ± 68 μg/L). The concentrations were compared to wells and cborehole waters in sixth neighborhood of Cotonou. We have used statistical analyzers such as MANOVA which have made it possible to classify the waters and metals in the ecosystems studied compared to groundwater and Well water waters. We use hierarchical clustering on principal components to identify similarities between stations based on metal concentration with R software packages “FactoMineR” and “factoextra”. In general, we can conclude that most of the metals have an anthropogenic source except strontium and major elements (Ca and Mg) which could respectively provide from marine waters and geochemical sources.
基金the National Natural Science Foundation of China (No. 50471101)the Flan-ders-China Bilateral Project BIL 02/04.
文摘Diffusion couples,WC/Co-1at.%C,V8C7/Co,and WC/Co-0.3wt.%V8C7 were constructed and annealed at temperatures ranging from 1100 to 1300℃. The concentration profile of V and W atoms in these couples were measured by EPMA. Aided by Thermo-calc & DICTRA software package,the concentration profiles of W and V in established diffusion couples were calculated by the moving boundary model according to revised dynamic parameters and MOB database,respectively. Then the concentration profile of W in Co binder during sintering WC-Co cemented carbide was simulated by the Cell model. It can provide reference for composition and sintering process design of cemented carbides with high performance. Meanwhile,the validity of revised dynamic parameters of the W-C-Co-V system is verified by the comparison of experimental and simulated results.
文摘AISI H13 hot work tool steel is widely used for hot forging, hot-extrusion and die-casting because of its high temperature strength, impact toughness, heat checking resistance and wear resistance, etc. The thermally induced surface damage, i. e., thermal fatigne,is believed to be controlled by the magnitude of the imposed cyclic strain. The thermal fatigue on the surface of hot working die, which is responsible to the initiation of the cracks, is reported to result in more than 80 % of the failure of dies.
文摘Thermo-Calc software package (TCP+DICTRA) was used to simulate the carbide transformation process in die steel for plastic. Combined with TEM analysis, the calculated result confirms that the carbide in equilibrium state is M_7C_3 carbide. The dissolution of M_7C_3 carbide in steel is predicted by DICTRA program. It was shown that the temperature remarkably affects the dissolution process of M_7C_3 carbide, but the influence of alloy elements such as manganese and molybdenum can be neglected in this steel.
文摘Core axial power distribution is an essential topic in pressurized water reactor(PWR)reactivity control.Traditional PWRs limit stability against axial core power oscillations at a high-cycle burnup.Because the‘‘camel’’peak power shape typically occurs with increasing depletion,the approaches used for the axial power control deserve special attention.This study aims to investigate the performance of different gadolinium rod design schemes in core axial power control during power operation based on the reactivity balance strategy,and to propose new multiconcentration gadolinium rod design schemes.In the new design schemes,low-concentration gadolinium pellets are filled in the axial hump part of the gadolinium rod,and high-concentration gadolinium pellets are filled in the other parts.The impact of different gadolinium rod design schemes on the main core characteristics was evaluated using the nuclear design code package PCM developed by CGN.The results show that the new gadolinium rod design significantly impacts the core axial power shape.The new design schemes can efficiently improve the core axial power distribution along the entire cycle by reducing the core axial power peak at the end of a cycle,enhancing the reactor operation stability,and achieving a better core safety margin,revealing a sizeable potential application.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11825403,12188101,and 11804138)the Natural Science Foundation of Anhui Province,China(Grant No.1908085MA10)the Opening Foundation of the State Key Laboratory of Surface Physics of Fudan University(Grant No.KF2019_07)。
文摘Magnetics,ferroelectrics,and multiferroics have attracted great attentions because they are not only extremely im-portant for investigating fundamental physics,but also have important applications in information technology.Here,recent computational studies on magnetism and ferroelectricity are reviewed.We first give a brief introduction to magnets,fer-roelectrics,and multiferroics.Then,theoretical models and corresponding computational methods for investigating these materials are presented.In particular,a new method for computing the linear magnetoelectric coupling tensor without applying an external field in the first principle calculations is proposed for the first time.The functionalities of our home-made Property Analysis and Simulation Package for materials(PASP)and its applications in the field of magnetism and ferroelectricity are discussed.Finally,we summarize this review and give a perspective on possible directions of future computational studies on magnetism and ferroelectricity.
基金Supported by the National Natural Science Foundation of China (No.90209004)E-Institute Construction Plan Project of Shanghai Municipal Education Committee(No.E03008)
文摘Objective: To determine the bioinformatical characteristics of differential gene expression in patients with chronic superficial gastritis (CSG) with the Pi-deficiency syndrome (PDS) and those of the non- Pi-deficiency syndrome (non-PDS), i.e. patients of CSG with Pi (脾)-Wei (胃) dampnese-heat syndrome and healthy persons. Methods: With the BRB-Array Tools software package, original data collection and bioinformatic analysis of gene arrays were conducted in 6 CSG patients of PDS (CSG-PDS), 6 CSG patients of non-PDS (CSG-nPDS), and 6 healthy volunteers (Normal). Results: Compared with non-PDS, the gene expressions in PDS with regards to protein synthesis, energy metabolism, immune reaction and ionic transport tended to be down-regulated, while those concerning secretion, cytoskeleton and ubiquitinization were up-regulated dominantly. Conclusions: The two kinds of samples, CSG-PDS/Normal and CSG-PDS/CSG-nPDS, have their respective gene expression profiles with different characteristics. Gene expression profile has certain referential significance in syndrome classification.
基金supported by the Ministry of Education and Science of the Republic of Kazakhstan under grants 1415/GF(IPS-21),1102/GF(ITT-5).
文摘In this paper we present a software package based on modern information technologies that allows rapid analysis and visualization of the properties of complex plasmas.The properties of plasma are simulated by two means.First of all,we have applied the molecular dynamics simulation method which numerically solves the equations of motions for plasma particles.Secondly,we calculate microscopic properties of plasma by using the Boltzmann equation with additional relations,initial and boundary conditions.
基金a project funded by the European Union contracts H2020-INFRAEDI-02-2018823830,and H2020-EINFRA-2015-1675728funded through EOSC-Life(https://www.eosc-life.eu)contract H2020-INFRAEOSC-2018-2824087ELIXIR-CONVERGE(https://elixir-europe.org)contract H2020-INFRADEV-2019-2871075.
文摘We introduce the concept of Canonical Workflow Building Blocks(CWBB),a methodology of describing and wrapping computational tools,in order for them to be utilised in a reproducible manner from multiple workflow languages and execution platforms.The concept is implemented and demonstrated with the BioExcel Building Blocks library(BioBB),a collection of tool wrappers in the field of computational biomolecular simulation.Interoperability across different workflow languages is showcased through a protein Molecular Dynamics setup transversal workflow,built using this library and run with 5 different Workflow Manager Systems(WfMS).We argue such practice is a necessary requirement for FAIR Computational Workflows and an element of Canonical Workflow Frameworks for Research(CWFR)in order to improve widespread adoption and reuse of computational methods across workflow language barriers.