Background: Cognitive impairment becomes more common with ageing and may benefit from intervention. In a Spanish speaking population, detection of cognitive impairment by a general practitioner in Primary Care can be ...Background: Cognitive impairment becomes more common with ageing and may benefit from intervention. In a Spanish speaking population, detection of cognitive impairment by a general practitioner in Primary Care can be a problem, as many of the standard tests target English speaking populations. The Memory Impairment Screen (MIS-A) is a validated test using English words to detect Alzheimer’s Disease (AD) and other dementias. We have modified this test to suit a Spanish speaking population and added a new component, delayed recall. We have called our new test the Memory Impairment Screen with Delayed Recall (MIS-D). Objectives: 1) To test a Spanish version of MIS-A and MIS-D. 2) To assess the discriminative validity of MIS-D as a screening tool for the amnestic variant of Mild Cognitive Impairment (aMCI) in a group of Spanish speaking people aged 65 years old and over. Methods: A case-control study of a cohort of 739 native Spanish speaking residents of Buenos Aires aged 65 years old and over, of whom 436 were healthy controls and 303 had a diagnosis of aMCI. Measurements: Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NVP) were estimated for MIS-D and MIS-A. Results: Normative values for MIS-A and MIS-D were obtained from the control population. Both age and education significantly affected these values (p < 0.0001). Control participants showed significant differences for both modalities, MIS-A and MIS-D. The cut-off for MIS-A should be 7.5 and for MIS-D, 5.5. Comparison between control population and aMCI population using ROC curve gave a result of 5.5 in MIS-D, with 97% specificity and 76% sensitivity. Conclusion: MIS-D was positively predictive of aMCI, with 97% specificity and 76% sensitivity in a sample of Spanish speaking patients aged 65 years old and over in Buenos Aires.展开更多
Background:As sedentary behavior is a global health issue,there is a need for methods of self-reported sitting assessment.The accuracy and reliability of these methods should also be tested in various populations and ...Background:As sedentary behavior is a global health issue,there is a need for methods of self-reported sitting assessment.The accuracy and reliability of these methods should also be tested in various populations and different cultural contexts.This study examined the validity of longterm and short-term recall of occupational sitting time in Finnish and Chinese subgroups.Methods:Two cohort groups of office-based workers(58.6%female,age range 2267 years)participated:a Finnish group(FIN,n=34)and a Chinese group(CHI,n=36).Long-term(past 3-month sitting)and short-term(daily sitting assessed on 5 consecutive days)single-item measures were used to assess self-reported occupational sitting time.Values from each participant were compared to objectively measured occupational sitting time assessed via thigh-mounted accelerometers,with Spearman’s rho(r)used to assess validity and the Bland-Altman method used to evaluate agreement.Coefficients of variation depicted day-to-day variability of time spent on sitting at work.Results:In the total study sample,the results showed that both long-term and short-term recall correlated with accelerometer-derived sitting time(r=0.532,95%confidence intervals(CI):0.3360.684,p<0.001;r=0.533,95%CI:0.4490.607,p<0.001,respectively).Compared to objectively measured sitting time,self-reported occupational sitting time was 2.4%(95%CI:0.5%to 5.3%,p=0.091)and 2.2%(95%CI:0.7%3.6%,p=0.005)greater for long-term and short-term recall,respectively.The agreement level was within the range21.2%to 25.9%for long-term recall,and24.2%to 28.5%for short-term recall.During a 5-day work week,day-to-day variation of sitting time was 9.4%§11.4%according to short-term recall and 10.4%§8.4%according to accelerometry-derived occupational sitting time.Conclusion:Overall,both long-term and short-term self-reported instruments provide acceptable measures of occupational sitting time in an office-based workplace,but their utility at the individual level is limited due to large variability.展开更多
A 57-year-old woman underwent abdominal surgery with a subarachnoid block supplemented by “light” general endotracheal anesthesia consisting of a propofol infusion and a sub-MAC concentration of sevoflurane. The pre...A 57-year-old woman underwent abdominal surgery with a subarachnoid block supplemented by “light” general endotracheal anesthesia consisting of a propofol infusion and a sub-MAC concentration of sevoflurane. The previous case in the same operating room had involved a malignant hyperthermia-susceptible patient, and charcoal filters had been placed in the breathing circuit as a precautionary measure. Because it had not been used on the evening beforehand, the circuit with filters was left in situ with a strip of tape indicating that it was clean. The woman’s anesthesiologist assumed that these filters were heat and moisture exchanger filters in an unused circuit and therefore did not remove them. Subsequently, the patient had awareness with intraoperative recall. This case highlights the potential for inadvertent use of activated charcoal filters with potentially catastrophic results. Such unintended utilization of these products likely can be minimized by improved labeling techniques.展开更多
<strong>Objective</strong><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">: Determine the Test reliability a...<strong>Objective</strong><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">: Determine the Test reliability and the objective validity of the International Physical Activity Questionnaire (IPAQ). </span><b><span style="font-family:Verdana;font-size:12px;">Methods</span></b></span><span style="font-family:Verdana;">:</span><span style="font-family:Verdana;"> IPAQ was evaluated for test-retest reliability within 6</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">8 days of its first administration. Criterion validity was tested comparing IPAQ data with those from an activity meter (Intelligent Device for Energy Expenditure and Activity, IDEEA). </span><b><span style="font-family:Verdana;font-size:12px;">Results</span></b><span style="font-family:Verdana;font-size:12px;">: The test-retest correlation (n = 71) for items of IPAQ ranged from r = 0.63 to r = 0.74 and w</span></span><span style="font-family:Verdana;">as </span><span style="font-family:Verdana;">r = 0.79 for the total weekly PA in MET*min per week. Average PA (in MET*min/week) measured with the IDEEA meter, decreased from normal (15</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">840), to 14</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">278 in overweight</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">(BMI</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">></span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">25-</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">30) and further to 12</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">803 in obese subjects (>30. BMI). The weekly energy expenditure measured by IDEEA correlated significantly (r = 0</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">61,</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">r</span><sup><span style="font-family:Verdana;font-size:12px;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> = 0.38) with the IPAQ data, providing an objective criterion for validity of IPAQ. The mean values of weekly PA estimated from IPAQ (in MET*min/week) differed significantly in the high (15</span></span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">690) vs. the low (11</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">398) activity groups but not between the moderate (12</span><span style="font-family:Verdana;">,</span><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">056) compared to the low PA group. The IPAQ criteria used to categorize subjects as moderately active, erred by including too many low PA subjects. IDEEA measurements in sedentary subjects overestimated their energy expenditure. </span><b><span style="font-family:Verdana;font-size:12px;">Conclusions</span></b><span style="font-family:Verdana;font-size:12px;">: IPAQ can be reliably used to distinguish low and high PA groups and yields relatively low estimates (−</span></span><span style="font-family:Verdana;">18%) of weekly PA in these groups compared to those measured with the activity meter. Stricter criteria are needed to distinguish moderate from low PA groups. Overweight and obese subjects showed significantly lower levels of PA than normal BMI subjects.</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">IDEEA overestimates low levels of PA.</span>展开更多
BACKGROUND Radiation recall dermatitis has been defined as the "recalling" by skin of previous radiation exposure in response to the administration of certain response-inducing drugs. Although the phenomenon...BACKGROUND Radiation recall dermatitis has been defined as the "recalling" by skin of previous radiation exposure in response to the administration of certain response-inducing drugs. Although the phenomenon is relatively well known in the medical world,an exact cause has not been documented.CASE SUMMARY Here, we report the rare occurrence of radiation recall dermatitis after palliative radiotherapy for bone metastases in a metastatic melanoma patient treated with a combination of dabrafenib and trametinib.CONCLUSION We present a case of radiation recall dermatitis after completion of palliative radiotherapy while being treated with a combination of dabrafenib and trametinib. This is a very rare toxic event, and there is insufficient data to describe prevention strategies. Increased awareness and reporting of cases will help to better explain the association between targeted therapy and the radiation recall phenomenon.展开更多
According to the wire and nozzle movement track in groove, the movement parameters of wire were memorized and recalled for the following top welds by using a single chip computer. In this paper, it was also discussed...According to the wire and nozzle movement track in groove, the movement parameters of wire were memorized and recalled for the following top welds by using a single chip computer. In this paper, it was also discussed that the design problems of correcting deviation of wire movement track in narrow gap submerged arc welding process must be noticed in order to obtain the sound welding result.展开更多
This paper addressed a statistical analysis for the recall of parallel intraconnected bidirectional associative memory-Modified Intraconnected Bidirectional Associative Memory (MIBAM) and proved the conclusions: two M...This paper addressed a statistical analysis for the recall of parallel intraconnected bidirectional associative memory-Modified Intraconnected Bidirectional Associative Memory (MIBAM) and proved the conclusions: two MIBAM with the equal total number of neurons have the equal recalling probability for m pairs of stored pattern pairs if m is not too large. So they have the same capacity and same error correcting ability, i. e., their performances are statistically equivalent. The results of simulation support the conclusions well.展开更多
Purpose: To determine whether a global physical activity question (GPAq) administered in young adulthood can be used to accurately rank former physical activity levels (PA) relative to peers of the same age and sex du...Purpose: To determine whether a global physical activity question (GPAq) administered in young adulthood can be used to accurately rank former physical activity levels (PA) relative to peers of the same age and sex during adolescence. Methods: Data were obtained from the Physical Activity in Young Adults Study, a 10- year follow-up study of 12 - 16 year old adolescents. Five hundred twenty-eight young adults, mean age 24.5 (±1.0) years, completed a GPAq regarding current and past (adolescent) PA. GPAq answers were used to determine whether young adults could accurately rank their past (adolescent) PA levels relative to peers of the same age and sex. GPAq responses were compared with actual self-reported PA levels assessed by the Modifiable Activity Questionnaire for Adolescents (MAQ-A;collected during adolescence). For adolescent PA, an average of 4 years of activity from the MAQ-A 1990-1993, was used. Results: Regardless of gender, Jonckheere-Terpstra tests for trend (p < 0.0001) suggest significant linear trends across categories of PA level for the MAQ-A. Higher perceived PA tracked with greater past PA activity and lower perceived PA tracked with lower past PA activity. Conclusions: Young adults who classified themselves as more active as an adolescent were found to be relatively more active based upon self-reported activity from recall questionnaires collected during that time. These findings suggest that young adults can reasonably estimate relative PA levels during their adolescent years with GPAq. Global physical activity questions may be valid for the assessment and classification of previous PA levels.展开更多
Background: Early detection of dementia is currently of great interest and of crucial importance for the implementation of preventive measures and treatment of the disease. Impairment in verbal episodic memory, and in...Background: Early detection of dementia is currently of great interest and of crucial importance for the implementation of preventive measures and treatment of the disease. Impairment in verbal episodic memory, and in particular in a delayed recall phase, is considered one of the early markers of progression from mild cognitive impairment (MCI) to dementia. Therefore, having cognitive screening instruments with predictive value for progression is of utmost importance. Objective: The purpose of this work is to show the predictive value, sensitivity and specificity of the Memory Impairment Screen with delayed recall (MIS-DR) to predict conversion to dementia in patients with MCI. Methods: In retrospective study 502 patients over 60 years old, evaluated in the Older Adult Functional Evaluation Unit of our hospital for cognitive complaint, were diagnosed with MCI. They were followed up to assess conversion to dementia. Results: During follow up, 144 participants developed dementia (28.6%, 95% CI 24.76 - 32.85) and the average time of progression to dementia were 23 months (SD 13.2). The cut-off point was established below 6 for MIS-DR and it showed a sensitivity of 76% (95% CI 68.77 - 77.84) and a specificity of 56% (95% CI 50.44 - 61.58), with a positive predictive value of 41% (95% CI 34.78 - 47.6) and a negative predictive value of 85% (95% CI 80.53 - 91.11) for predicting progression to dementia. Of those patients who obtained a MIS-DR score below 6, 41% developed dementia, in contrast to 14.53% of those with a score above or equal to 6, OR 4.09 (95% CI 2.64 - 6.34), p 0.00001. There were no significant differences in terms of gender, education level or vascular risk factors among patients who converted and those who did not convert to dementia. Conclusion: We believe that MIS-DR is a useful and valid test to detect episodic memory impairment and to identify patients at risk of progression to dementia.展开更多
An experimental assessment of the effectiveness of university counselling was conducted through the “Stress Drawing Recall” Technique applied before and after a clinical colloquium with 70 university students of bot...An experimental assessment of the effectiveness of university counselling was conducted through the “Stress Drawing Recall” Technique applied before and after a clinical colloquium with 70 university students of both genders, aged 18 - 35 years, who had requested this service. Another 70 students waiting to undergo the colloquium were interviewed as a control group. Two parallel series of drawings depicting personal stress situations were collected and, after evaluation by three expert judges in “double-blind” conditions, led to establishing five forms of development of the graphic language from the first to second drawing, defined as follows: a) distension, with a reduction in stress indicators and increase in comfort indicators;b) explicit representation of conflict resolution;c) appearance of new elements, with persisting conflict;d) increase in stress indicators;e) invariant or equivalent repetition of the stress drawing. Results showed that students who underwent the clinical colloquium (experimental group) changed their stress drawings mainly in the direction of distension and conflict resolution, while the control group had more invariant or equivalent repetition of the stress situation (?= 62.77;p < 0.001). The events depicted in the stress drawings were divided into three categories: a) limited short-term stressful situations due to mainly external agents;b) externally induced stressful situations with intense emotional resonance;c) wide-ranging long-lasting stressful situations with great involvement of the self. The participants were divided into: a) very anxious subjects;b) averagely anxious subjects;c) not very anxious subjects, on the basis of their scores on two questionnaires: the MPI (1959) and the STAI (1970). There is a correspondence between the subjects’ level of conflict and extension of the depicted stress. This confirms the usefulness of the Stress Drawing Recall Technique in psychological counselling.展开更多
On aging, spatial memory declines to some degree in both, rodents and humans. It is unknown, however, whether aging brings about a decline of encoding and retrieval of spatial information in parallel. The present stud...On aging, spatial memory declines to some degree in both, rodents and humans. It is unknown, however, whether aging brings about a decline of encoding and retrieval of spatial information in parallel. The present study examined spatial encoding and retrieval in male CD-1 mice at 4, 9, and 12 months of age in a complex dry-land maze. The total time to reach the goal zone was age-dependent favoring mice at 4 months of age. We showed previously that moving time represents encoding of spatial information and resting time represents recall of previously learned spatial information. The average moving time decreased from 69.8 ± 5.3 s (mean ± SEM), 69.7 ± 8.0 s, and 78.9 ± 4.9 s to 17.0 ± 2.3 s (p < 0.001 ), 24.7 ± 2.7 s (p < 0.001), and 31.0 ± 3.5 s (p < 0.001) at 4, 9, and 12 months of age, respectively. The average resting time decreased from 34.9 ± 5.6 s, 22.2 ± 4.2 s, and 41.7 ± 5.3 s to 3.6 ± 1.2 s (p < 0.001), 5.3 ± 1.8 s (p = 0.009), and 22.7 ± 4.9 s (p = 0.007) at 4, 9, and 12 months of age, respectively. We conclude that age-related deficits of spatial memory in mice manifest with an encoding deficit prior to a retrieval deficit.展开更多
Radiation recall phenomenon is a tissue reaction that develops throughout a previously irradiated area,precipitated by the administration of certain drugs.Radiation recall is uncommon and easily neglected by physician...Radiation recall phenomenon is a tissue reaction that develops throughout a previously irradiated area,precipitated by the administration of certain drugs.Radiation recall is uncommon and easily neglected by physicians;hence,this phenomenon is underreported in literature.This manuscript reports two cases of radiation recall.First,a 44-year-old man with nasopharyngeal carcinoma was treated with radiotherapy in 2010 and subsequently developed multi-site bone metastases.A few days after the docetaxel-based chemotherapy,erythema and papules manifested dermatitis,as well as swallowing pain due to pharyngeal mucositis,developed on the head and neck that strictly corresponded to the previously irradiated areas.Second,a 19-year-old man with recurrent nasal NK/T cell lymphoma initially underwent radiotherapy followed by chemotherapy after five weeks.Erythema and edema appeared only at the irradiated skin.Both cases were considered chemotherapeutic agents that incurred radiation recall reactions.Clinicians should be knowledgeable of and pay attention to such rare phenomenon.展开更多
There are no explicit laws concerning food recalls in China; moreover, some related regulations have weaknesses. China should first create a system of laws and regulations governing food recalls, establish a system to...There are no explicit laws concerning food recalls in China; moreover, some related regulations have weaknesses. China should first create a system of laws and regulations governing food recalls, establish a system to recall defective food, and strengthen administrative and legal remedial mechanisms related to consumer rights.展开更多
This study assessed the relationships between recall of positive and negative events, API (attention to positive) and ANI (attention to negative information), and perception of happiness, with the hypothesis that ...This study assessed the relationships between recall of positive and negative events, API (attention to positive) and ANI (attention to negative information), and perception of happiness, with the hypothesis that recall affects the perception of happiness and that ANI and API affect recall. One hundred and five women filled in the APNI scale to assess API and ANI and were asked to listen to and recall a story presenting both positive and negative events, and provide an assessment of the character perceived happiness. Finally, they were asked to choose an ending for the story. Results showed that recall is related to the perception of happiness more than API and ANI, and that relationships occur among recall, API, ANI, and perception of happiness. A positive ending for the story was preferred. Discussion focuses on the implications of individual differences in paying attention to and recall positive and negative information.展开更多
This paper examines the noise and rotation resistance capacity of Hopfield Neural Network (HNN) given four corrupted traffic sign images. In the study, Signal-to-Noise Ratio (SNR), recall rate and pattern complexi...This paper examines the noise and rotation resistance capacity of Hopfield Neural Network (HNN) given four corrupted traffic sign images. In the study, Signal-to-Noise Ratio (SNR), recall rate and pattern complexity are defined and employed to evaluate the recall performance. The experimental results indicate that the HNN possesses significant recall capacity against the strong noise corruption, and certain restoring competence to the rotation. It is also found that combining noise with rotation does not further challenge the HNN corruption resistance capability as the noise or rotation alone does.展开更多
To study recall accuracy of the offensive and defensive situations including movements of elite-athlete/novice oneself, a novel experimental system was developed where defensive actions were performed by the subject w...To study recall accuracy of the offensive and defensive situations including movements of elite-athlete/novice oneself, a novel experimental system was developed where defensive actions were performed by the subject with a CG (Computer Graphics) player who presented predetermined offensive actions. Both the CG player's movements and subject's movements were reproduced by a video using mixed reality technology for recall examination. This system was also designed to rearrange the natural sequence of image frames resulting in a reproducible video in which the time relation of offense and defense was falsified. Displacement of timing in the false video was twofold; delayed from the truth or advanced from the truth. Using this two-video, true/false imagery method, the subject was asked to select the true video by recall; thus it became possible to examine the recall accuracy quantitatively by controlling the timing displacement. Results of the experiment using this system revealed that karate expert possessed a skill to recognize the time relation between the opponent's movement and one's own movement perceptually that was more developed than that of the novice. It was further identified that the expert as well as the novice recognized delayed displacement more accurately than they could recognize advanced displacement.展开更多
For the purpose of enhancing automobile safety and the effectiveness of recalls,increasing manufacturers' quality control capabilities,and reducing defects,we investigated thestatus of recalls over the last five y...For the purpose of enhancing automobile safety and the effectiveness of recalls,increasing manufacturers' quality control capabilities,and reducing defects,we investigated thestatus of recalls over the last five years.We have examined patterns and trends in motor vehiclesafety recalls using databases from China,Europe and the United States.A recall rate parameterwas developed to evaluate the level of recall enforcement based on analyzing the reasonsfor recalls and manufactures' characteristics.Moreover,there were substantial differencesin the recall rates of China compared with those in other countries,indicating that Chinese manufacturersneed to take more active action in recall.展开更多
文摘Background: Cognitive impairment becomes more common with ageing and may benefit from intervention. In a Spanish speaking population, detection of cognitive impairment by a general practitioner in Primary Care can be a problem, as many of the standard tests target English speaking populations. The Memory Impairment Screen (MIS-A) is a validated test using English words to detect Alzheimer’s Disease (AD) and other dementias. We have modified this test to suit a Spanish speaking population and added a new component, delayed recall. We have called our new test the Memory Impairment Screen with Delayed Recall (MIS-D). Objectives: 1) To test a Spanish version of MIS-A and MIS-D. 2) To assess the discriminative validity of MIS-D as a screening tool for the amnestic variant of Mild Cognitive Impairment (aMCI) in a group of Spanish speaking people aged 65 years old and over. Methods: A case-control study of a cohort of 739 native Spanish speaking residents of Buenos Aires aged 65 years old and over, of whom 436 were healthy controls and 303 had a diagnosis of aMCI. Measurements: Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NVP) were estimated for MIS-D and MIS-A. Results: Normative values for MIS-A and MIS-D were obtained from the control population. Both age and education significantly affected these values (p < 0.0001). Control participants showed significant differences for both modalities, MIS-A and MIS-D. The cut-off for MIS-A should be 7.5 and for MIS-D, 5.5. Comparison between control population and aMCI population using ROC curve gave a result of 5.5 in MIS-D, with 97% specificity and 76% sensitivity. Conclusion: MIS-D was positively predictive of aMCI, with 97% specificity and 76% sensitivity in a sample of Spanish speaking patients aged 65 years old and over in Buenos Aires.
基金supported by the China Scholarship Council(No.201206320092),China.
文摘Background:As sedentary behavior is a global health issue,there is a need for methods of self-reported sitting assessment.The accuracy and reliability of these methods should also be tested in various populations and different cultural contexts.This study examined the validity of longterm and short-term recall of occupational sitting time in Finnish and Chinese subgroups.Methods:Two cohort groups of office-based workers(58.6%female,age range 2267 years)participated:a Finnish group(FIN,n=34)and a Chinese group(CHI,n=36).Long-term(past 3-month sitting)and short-term(daily sitting assessed on 5 consecutive days)single-item measures were used to assess self-reported occupational sitting time.Values from each participant were compared to objectively measured occupational sitting time assessed via thigh-mounted accelerometers,with Spearman’s rho(r)used to assess validity and the Bland-Altman method used to evaluate agreement.Coefficients of variation depicted day-to-day variability of time spent on sitting at work.Results:In the total study sample,the results showed that both long-term and short-term recall correlated with accelerometer-derived sitting time(r=0.532,95%confidence intervals(CI):0.3360.684,p<0.001;r=0.533,95%CI:0.4490.607,p<0.001,respectively).Compared to objectively measured sitting time,self-reported occupational sitting time was 2.4%(95%CI:0.5%to 5.3%,p=0.091)and 2.2%(95%CI:0.7%3.6%,p=0.005)greater for long-term and short-term recall,respectively.The agreement level was within the range21.2%to 25.9%for long-term recall,and24.2%to 28.5%for short-term recall.During a 5-day work week,day-to-day variation of sitting time was 9.4%§11.4%according to short-term recall and 10.4%§8.4%according to accelerometry-derived occupational sitting time.Conclusion:Overall,both long-term and short-term self-reported instruments provide acceptable measures of occupational sitting time in an office-based workplace,but their utility at the individual level is limited due to large variability.
文摘A 57-year-old woman underwent abdominal surgery with a subarachnoid block supplemented by “light” general endotracheal anesthesia consisting of a propofol infusion and a sub-MAC concentration of sevoflurane. The previous case in the same operating room had involved a malignant hyperthermia-susceptible patient, and charcoal filters had been placed in the breathing circuit as a precautionary measure. Because it had not been used on the evening beforehand, the circuit with filters was left in situ with a strip of tape indicating that it was clean. The woman’s anesthesiologist assumed that these filters were heat and moisture exchanger filters in an unused circuit and therefore did not remove them. Subsequently, the patient had awareness with intraoperative recall. This case highlights the potential for inadvertent use of activated charcoal filters with potentially catastrophic results. Such unintended utilization of these products likely can be minimized by improved labeling techniques.
文摘<strong>Objective</strong><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">: Determine the Test reliability and the objective validity of the International Physical Activity Questionnaire (IPAQ). </span><b><span style="font-family:Verdana;font-size:12px;">Methods</span></b></span><span style="font-family:Verdana;">:</span><span style="font-family:Verdana;"> IPAQ was evaluated for test-retest reliability within 6</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">-</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">8 days of its first administration. Criterion validity was tested comparing IPAQ data with those from an activity meter (Intelligent Device for Energy Expenditure and Activity, IDEEA). </span><b><span style="font-family:Verdana;font-size:12px;">Results</span></b><span style="font-family:Verdana;font-size:12px;">: The test-retest correlation (n = 71) for items of IPAQ ranged from r = 0.63 to r = 0.74 and w</span></span><span style="font-family:Verdana;">as </span><span style="font-family:Verdana;">r = 0.79 for the total weekly PA in MET*min per week. Average PA (in MET*min/week) measured with the IDEEA meter, decreased from normal (15</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">840), to 14</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">278 in overweight</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">(BMI</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">></span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">25-</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;"><</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">30) and further to 12</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">803 in obese subjects (>30. BMI). The weekly energy expenditure measured by IDEEA correlated significantly (r = 0</span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">61,</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">r</span><sup><span style="font-family:Verdana;font-size:12px;">2</span></sup><span style="font-family:Verdana;font-size:12px;"> = 0.38) with the IPAQ data, providing an objective criterion for validity of IPAQ. The mean values of weekly PA estimated from IPAQ (in MET*min/week) differed significantly in the high (15</span></span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">690) vs. the low (11</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;">398) activity groups but not between the moderate (12</span><span style="font-family:Verdana;">,</span><span style="font-size:10pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;">056) compared to the low PA group. The IPAQ criteria used to categorize subjects as moderately active, erred by including too many low PA subjects. IDEEA measurements in sedentary subjects overestimated their energy expenditure. </span><b><span style="font-family:Verdana;font-size:12px;">Conclusions</span></b><span style="font-family:Verdana;font-size:12px;">: IPAQ can be reliably used to distinguish low and high PA groups and yields relatively low estimates (−</span></span><span style="font-family:Verdana;">18%) of weekly PA in these groups compared to those measured with the activity meter. Stricter criteria are needed to distinguish moderate from low PA groups. Overweight and obese subjects showed significantly lower levels of PA than normal BMI subjects.</span><span style="font-size:10pt;font-family:;" "=""> </span><span style="font-family:Verdana;">IDEEA overestimates low levels of PA.</span>
文摘BACKGROUND Radiation recall dermatitis has been defined as the "recalling" by skin of previous radiation exposure in response to the administration of certain response-inducing drugs. Although the phenomenon is relatively well known in the medical world,an exact cause has not been documented.CASE SUMMARY Here, we report the rare occurrence of radiation recall dermatitis after palliative radiotherapy for bone metastases in a metastatic melanoma patient treated with a combination of dabrafenib and trametinib.CONCLUSION We present a case of radiation recall dermatitis after completion of palliative radiotherapy while being treated with a combination of dabrafenib and trametinib. This is a very rare toxic event, and there is insufficient data to describe prevention strategies. Increased awareness and reporting of cases will help to better explain the association between targeted therapy and the radiation recall phenomenon.
文摘According to the wire and nozzle movement track in groove, the movement parameters of wire were memorized and recalled for the following top welds by using a single chip computer. In this paper, it was also discussed that the design problems of correcting deviation of wire movement track in narrow gap submerged arc welding process must be noticed in order to obtain the sound welding result.
基金Supported by Climbing Program-National Key Project for Fundamental Research in China
文摘This paper addressed a statistical analysis for the recall of parallel intraconnected bidirectional associative memory-Modified Intraconnected Bidirectional Associative Memory (MIBAM) and proved the conclusions: two MIBAM with the equal total number of neurons have the equal recalling probability for m pairs of stored pattern pairs if m is not too large. So they have the same capacity and same error correcting ability, i. e., their performances are statistically equivalent. The results of simulation support the conclusions well.
文摘Purpose: To determine whether a global physical activity question (GPAq) administered in young adulthood can be used to accurately rank former physical activity levels (PA) relative to peers of the same age and sex during adolescence. Methods: Data were obtained from the Physical Activity in Young Adults Study, a 10- year follow-up study of 12 - 16 year old adolescents. Five hundred twenty-eight young adults, mean age 24.5 (±1.0) years, completed a GPAq regarding current and past (adolescent) PA. GPAq answers were used to determine whether young adults could accurately rank their past (adolescent) PA levels relative to peers of the same age and sex. GPAq responses were compared with actual self-reported PA levels assessed by the Modifiable Activity Questionnaire for Adolescents (MAQ-A;collected during adolescence). For adolescent PA, an average of 4 years of activity from the MAQ-A 1990-1993, was used. Results: Regardless of gender, Jonckheere-Terpstra tests for trend (p < 0.0001) suggest significant linear trends across categories of PA level for the MAQ-A. Higher perceived PA tracked with greater past PA activity and lower perceived PA tracked with lower past PA activity. Conclusions: Young adults who classified themselves as more active as an adolescent were found to be relatively more active based upon self-reported activity from recall questionnaires collected during that time. These findings suggest that young adults can reasonably estimate relative PA levels during their adolescent years with GPAq. Global physical activity questions may be valid for the assessment and classification of previous PA levels.
文摘Background: Early detection of dementia is currently of great interest and of crucial importance for the implementation of preventive measures and treatment of the disease. Impairment in verbal episodic memory, and in particular in a delayed recall phase, is considered one of the early markers of progression from mild cognitive impairment (MCI) to dementia. Therefore, having cognitive screening instruments with predictive value for progression is of utmost importance. Objective: The purpose of this work is to show the predictive value, sensitivity and specificity of the Memory Impairment Screen with delayed recall (MIS-DR) to predict conversion to dementia in patients with MCI. Methods: In retrospective study 502 patients over 60 years old, evaluated in the Older Adult Functional Evaluation Unit of our hospital for cognitive complaint, were diagnosed with MCI. They were followed up to assess conversion to dementia. Results: During follow up, 144 participants developed dementia (28.6%, 95% CI 24.76 - 32.85) and the average time of progression to dementia were 23 months (SD 13.2). The cut-off point was established below 6 for MIS-DR and it showed a sensitivity of 76% (95% CI 68.77 - 77.84) and a specificity of 56% (95% CI 50.44 - 61.58), with a positive predictive value of 41% (95% CI 34.78 - 47.6) and a negative predictive value of 85% (95% CI 80.53 - 91.11) for predicting progression to dementia. Of those patients who obtained a MIS-DR score below 6, 41% developed dementia, in contrast to 14.53% of those with a score above or equal to 6, OR 4.09 (95% CI 2.64 - 6.34), p 0.00001. There were no significant differences in terms of gender, education level or vascular risk factors among patients who converted and those who did not convert to dementia. Conclusion: We believe that MIS-DR is a useful and valid test to detect episodic memory impairment and to identify patients at risk of progression to dementia.
文摘An experimental assessment of the effectiveness of university counselling was conducted through the “Stress Drawing Recall” Technique applied before and after a clinical colloquium with 70 university students of both genders, aged 18 - 35 years, who had requested this service. Another 70 students waiting to undergo the colloquium were interviewed as a control group. Two parallel series of drawings depicting personal stress situations were collected and, after evaluation by three expert judges in “double-blind” conditions, led to establishing five forms of development of the graphic language from the first to second drawing, defined as follows: a) distension, with a reduction in stress indicators and increase in comfort indicators;b) explicit representation of conflict resolution;c) appearance of new elements, with persisting conflict;d) increase in stress indicators;e) invariant or equivalent repetition of the stress drawing. Results showed that students who underwent the clinical colloquium (experimental group) changed their stress drawings mainly in the direction of distension and conflict resolution, while the control group had more invariant or equivalent repetition of the stress situation (?= 62.77;p < 0.001). The events depicted in the stress drawings were divided into three categories: a) limited short-term stressful situations due to mainly external agents;b) externally induced stressful situations with intense emotional resonance;c) wide-ranging long-lasting stressful situations with great involvement of the self. The participants were divided into: a) very anxious subjects;b) averagely anxious subjects;c) not very anxious subjects, on the basis of their scores on two questionnaires: the MPI (1959) and the STAI (1970). There is a correspondence between the subjects’ level of conflict and extension of the depicted stress. This confirms the usefulness of the Stress Drawing Recall Technique in psychological counselling.
文摘On aging, spatial memory declines to some degree in both, rodents and humans. It is unknown, however, whether aging brings about a decline of encoding and retrieval of spatial information in parallel. The present study examined spatial encoding and retrieval in male CD-1 mice at 4, 9, and 12 months of age in a complex dry-land maze. The total time to reach the goal zone was age-dependent favoring mice at 4 months of age. We showed previously that moving time represents encoding of spatial information and resting time represents recall of previously learned spatial information. The average moving time decreased from 69.8 ± 5.3 s (mean ± SEM), 69.7 ± 8.0 s, and 78.9 ± 4.9 s to 17.0 ± 2.3 s (p < 0.001 ), 24.7 ± 2.7 s (p < 0.001), and 31.0 ± 3.5 s (p < 0.001) at 4, 9, and 12 months of age, respectively. The average resting time decreased from 34.9 ± 5.6 s, 22.2 ± 4.2 s, and 41.7 ± 5.3 s to 3.6 ± 1.2 s (p < 0.001), 5.3 ± 1.8 s (p = 0.009), and 22.7 ± 4.9 s (p = 0.007) at 4, 9, and 12 months of age, respectively. We conclude that age-related deficits of spatial memory in mice manifest with an encoding deficit prior to a retrieval deficit.
文摘Radiation recall phenomenon is a tissue reaction that develops throughout a previously irradiated area,precipitated by the administration of certain drugs.Radiation recall is uncommon and easily neglected by physicians;hence,this phenomenon is underreported in literature.This manuscript reports two cases of radiation recall.First,a 44-year-old man with nasopharyngeal carcinoma was treated with radiotherapy in 2010 and subsequently developed multi-site bone metastases.A few days after the docetaxel-based chemotherapy,erythema and papules manifested dermatitis,as well as swallowing pain due to pharyngeal mucositis,developed on the head and neck that strictly corresponded to the previously irradiated areas.Second,a 19-year-old man with recurrent nasal NK/T cell lymphoma initially underwent radiotherapy followed by chemotherapy after five weeks.Erythema and edema appeared only at the irradiated skin.Both cases were considered chemotherapeutic agents that incurred radiation recall reactions.Clinicians should be knowledgeable of and pay attention to such rare phenomenon.
文摘There are no explicit laws concerning food recalls in China; moreover, some related regulations have weaknesses. China should first create a system of laws and regulations governing food recalls, establish a system to recall defective food, and strengthen administrative and legal remedial mechanisms related to consumer rights.
文摘This study assessed the relationships between recall of positive and negative events, API (attention to positive) and ANI (attention to negative information), and perception of happiness, with the hypothesis that recall affects the perception of happiness and that ANI and API affect recall. One hundred and five women filled in the APNI scale to assess API and ANI and were asked to listen to and recall a story presenting both positive and negative events, and provide an assessment of the character perceived happiness. Finally, they were asked to choose an ending for the story. Results showed that recall is related to the perception of happiness more than API and ANI, and that relationships occur among recall, API, ANI, and perception of happiness. A positive ending for the story was preferred. Discussion focuses on the implications of individual differences in paying attention to and recall positive and negative information.
基金Supported by the Natural Science Foundation of Zhejiang Province(No.2010A610105)
文摘This paper examines the noise and rotation resistance capacity of Hopfield Neural Network (HNN) given four corrupted traffic sign images. In the study, Signal-to-Noise Ratio (SNR), recall rate and pattern complexity are defined and employed to evaluate the recall performance. The experimental results indicate that the HNN possesses significant recall capacity against the strong noise corruption, and certain restoring competence to the rotation. It is also found that combining noise with rotation does not further challenge the HNN corruption resistance capability as the noise or rotation alone does.
文摘To study recall accuracy of the offensive and defensive situations including movements of elite-athlete/novice oneself, a novel experimental system was developed where defensive actions were performed by the subject with a CG (Computer Graphics) player who presented predetermined offensive actions. Both the CG player's movements and subject's movements were reproduced by a video using mixed reality technology for recall examination. This system was also designed to rearrange the natural sequence of image frames resulting in a reproducible video in which the time relation of offense and defense was falsified. Displacement of timing in the false video was twofold; delayed from the truth or advanced from the truth. Using this two-video, true/false imagery method, the subject was asked to select the true video by recall; thus it became possible to examine the recall accuracy quantitatively by controlling the timing displacement. Results of the experiment using this system revealed that karate expert possessed a skill to recognize the time relation between the opponent's movement and one's own movement perceptually that was more developed than that of the novice. It was further identified that the expert as well as the novice recognized delayed displacement more accurately than they could recognize advanced displacement.
文摘For the purpose of enhancing automobile safety and the effectiveness of recalls,increasing manufacturers' quality control capabilities,and reducing defects,we investigated thestatus of recalls over the last five years.We have examined patterns and trends in motor vehiclesafety recalls using databases from China,Europe and the United States.A recall rate parameterwas developed to evaluate the level of recall enforcement based on analyzing the reasonsfor recalls and manufactures' characteristics.Moreover,there were substantial differencesin the recall rates of China compared with those in other countries,indicating that Chinese manufacturersneed to take more active action in recall.