BACKGROUND Intrahepatic duct(IHD)stones are among the most important risk factors for cholangiocarcinoma(CCC).Approximately 10%of patients with IHD stones develop CCC;however,there are limited studies regarding the ef...BACKGROUND Intrahepatic duct(IHD)stones are among the most important risk factors for cholangiocarcinoma(CCC).Approximately 10%of patients with IHD stones develop CCC;however,there are limited studies regarding the effect of IHD stone removal on CCC development.AIM To investigate the association between IHD stone removal and CCC development.METHODS We retrospectively analyzed 397 patients with IHD stones at a tertiary referral center between January 2011 and December 2020.RESULTS CCC occurred in 36 of the 397 enrolled patients.In univariate analysis,chronic hepatitis B infection(11.1%vs 3.0%,P=0.03),carbohydrate antigen 19-9(CA19-9,176.00 vs 11.96 II/mL,P=0.010),stone located in left or both lobes(86.1%vs 70.1%,P=0.042),focal atrophy(52.8%vs 26.9%,P=0.001),duct stricture(47.2%vs 24.9%,P=0.004),and removal status of IHD stone(33.3%vs 63.2%,P<0.001)were significantly different between IHD stone patients with and without CCC.In the multivariate analysis,CA19-9>upper normal limit,carcinoembryonic antigen>upper normal limit,stones located in the left or both lobes,focal atrophy,and complete removal of IHD stones without recurrence were independent factors influencing CCC development.However,the type of removal method was not associated with CCC risk.CONCLUSION Complete removal of IHD stones without recurrence could reduce CCC risk.展开更多
A field investigation was performed to study the content, speciation and mobility of vanadium, as well as microbial response in soil from a stone coal smelting district in Hunan province of China. The results showed t...A field investigation was performed to study the content, speciation and mobility of vanadium, as well as microbial response in soil from a stone coal smelting district in Hunan province of China. The results showed that the contents of soil V ranged from 168 to 1538 mg/kg, which exceeded the maximum permissible value of Canadian soil quality for V. The mean soil V content from wasteland area reached 1421 mg/kg, and those from the areas related with slag heap, ore pile and smelting center were 380, 260 and 225 mg/kg, respectively. Based on the results of the modified BCR sequential extraction procedure, V contents in the mobile fractions varied from 19.2 to 637 mg/kg accounting for 7.4%-42.3% of total V, and those of V(+5) species were between 21.9 and 534.0 mg/kg. Soil enzyme activity and microbial basal respiration were adversely affected by high level of soil V. More attention should be paid to soil V pollution and potential hazardous surrounding the stone coal smelting district.展开更多
The objective of this study is to develop an analytical methodology to evaluate the effectiveness of vibro stone column (S.C.) and dynamic compaction (D.C.) techniques supplemented with wick drains to densify and miti...The objective of this study is to develop an analytical methodology to evaluate the effectiveness of vibro stone column (S.C.) and dynamic compaction (D.C.) techniques supplemented with wick drains to densify and mitigate liquefaction in saturated sands and non-plastic silty soils. It includes the following: (i) develop numerical models to simulate and analyze soil densitication during S.C. installation and D.C. process, and (ii) identify parameters controlling post-improvement soil density in both cases, and (iii) develop design guidelines for densification of silty soils using the above techniques. An analytical procedure was developed and used to simulate soil response during S.C. and D.C. installations, and the results were compared with available case history data. Important construction design parameters and soil properties that affect the effectiveness of these techniques, and construction design choices suitable for sands and non-plastic silty soils were identified. The methodology is expected to advance the use of S.C. and D.C. in silty soils reducing the reliance on expensive field trials as a design tool. The ultimate outcome of this research will be design charts and design guidelines for using composite stone columns and composite dynamic compaction techniques in liquefaction mitigation of saturated silty soils.展开更多
Level soil bunds (LSB) and stone bunds (SB) have been widely implemented in the Bokole watershed since 2000 through support of the World Food Program (WFP). However, the performance of them against the target of the s...Level soil bunds (LSB) and stone bunds (SB) have been widely implemented in the Bokole watershed since 2000 through support of the World Food Program (WFP). However, the performance of them against the target of the structure has not been studied. This study analyzed the effect of LSB and SB on selected soil properties, when compared with nonterraced cropland. The Bokole watershed was divided into two units. From upper watershed, three croplands with LSB (aged 4, 6, and 9 years) and three nonterraced croplands each adjacent to one of the LSB were selected. Similarly, in lower watershed, SB aged 4, 6, and 8 years and three nonterraced croplands each adjacent to one of the SB were selected. From each cropland with LSB and SB, three composite soil samples (rep licates) were collected systematically in X designed rectangular plot. From each nonterraced cropland, three composite soil samples (replicates) were collected in X designed square plot. A total of 36 soil samples were analyzed for Soil Organic Carbon (SOC), Total Nitrogen (TN), Available Phosphorus (AP), Available Potassium (AK), pH, and Cation Exchange Capacity (CEC) following standard laboratory procedures. Most soil parameters were not significantly different in cropland with LSB and SB compared to nonterraced. However, in LSB aged 4 years and SB aged 6 years AP and pH were significantly less than their adjacent-nonterraced cropland. In SB aged 8 years, SOC, AP, AK, and pH were also significantly less than adjacent-nonterraced cropland. Past erosion, and past land uses are likely factors contributed to the observed result. It was inferred that the mean con tribution of LSB and SB alone for crop production with regard to analyzed soil parameters was not significant in the considered sites. Additional soil fertility management practices should be incorporated for better effect.展开更多
Lunan stone forest is a kind of typical karst in China, which is mainly developed under red soil. In the winter of 1999, three study sites were chosen in stone forest national park according to veget...Lunan stone forest is a kind of typical karst in China, which is mainly developed under red soil. In the winter of 1999, three study sites were chosen in stone forest national park according to vegetation cover, geomorphologic location and soil types. CO 2 concentration was measured with Gastec pump at different depths of soil (20, 40, 60 cm) and at the same time soil samples were gathered and soil properties such as soil moisture, pH, soil organic content were analyzed and the total number of viable microbes were counted in laboratory. In the study, dependent variable was chosen as the mean soil log (PCO 2 ), and soil properties were chosen as the independent variables. Multiple stepwise regression analysis showed that the total amount of microbes and soil moisture are the best indicators of the CO 2 production, with the equation LOG(PCO 2 ) = - 0.039(TNM) - 0.056(Mo) + 1.215 accounting for 86% of the variation of the soil CO 2 concentration, where TNM is the total number of microbes in the soil and Mo is the moisture of soil sample.展开更多
Stone column is one of the soil stabilizing methods that is used to increase bearing capacity and decrease the settlement of soft soils.Reinforced and unreinforced granular blankets are now being utilized to overcome ...Stone column is one of the soil stabilizing methods that is used to increase bearing capacity and decrease the settlement of soft soils.Reinforced and unreinforced granular blankets are now being utilized to overcome the problems of soft soils.In this research,the bearing capacity of stone columns,granular blanket,and a combination of both methods in reinforced and unreinforced modes were studied using scaled physical models.Results show that using granular blanket,stone column,and combination of both improves bearing capacity of soft soils.Using geogrid as the reinforcement of granular blankets and geotextile as stone-column encasement increases the efficiency of granular blankets and stone columns significantly.Additionally,in the case of using geotextile around the stone column,the stress concentration ratio of the stone column will increase as well as its rigidity and bearing capacity.展开更多
This paper studies the motion of novel manipulator that can be used in the structure of stone protectors of soil tillage implements. According to the virtual reality technology-based method the technology of compositi...This paper studies the motion of novel manipulator that can be used in the structure of stone protectors of soil tillage implements. According to the virtual reality technology-based method the technology of composition of the virtual model of a manipulator and its positions in the working process are described in details. This virtual model is used for composition the video clip, simulating the motion of novel manipulator, which three points are moving along two lines and one curve. The results obtained and the computer program realizing the virtual reality technology-based study of the working process of the virtual manipulators for stone protectors can be used by designers of stone protectors for soil tillage implements.展开更多
A very simple, ultra-sensitive, highly selective and non-extractive new spectrofluorimetric method for the determination of arsenic at pico-trace levels using 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been develope...A very simple, ultra-sensitive, highly selective and non-extractive new spectrofluorimetric method for the determination of arsenic at pico-trace levels using 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been developed. PTQA has been proposed as a new analytical reagent for the direct non-extractive spectrofluorimetric determination of Arsenic (V). This novel fluorimetric reagent, PTQA becomes oxidized in a slightly acidic (0.025 - 0.1 M H2SO4) solution with Arsenic (V) in absolute ethanol to produce highly fluorescent oxidized product (λex = 303 nm;λem = 365 nm). Constant and maximum fluorescence intensities were observed over a wide range of acidity (0.025 - 0.1 M H2SO4) for the period between 2 min and 24 h. Linear calibration graphs were obtained for 0.001 - 800-μgL-1 of As, having a detection limit of 0.1-ngL-1;the quantification limit of the reaction system was found to be 1-ngL-1 and the RSD was 0% - 2%. A large excess of over 60 cations, anions and complexion agents (like, chloride, phosphate, azide, tartrate, oxalate, SCN, etc.) do not interfere in the determination. The developed method was successfully used in the determination of arsenic in several Certified Reference Materials (alloys, steels, ores, human urine, hair, nails, bovine liver and sediments) as well as in some biological fluids (human blood, urine, hair, nail and milk), soil samples, food samples (vegetables, fruits, rice, corn and wheat), solutions containing both arsenic (III) and arsenic (V) speciation and complex synthetic mixtures. The results of the proposed method for assessing biological, food and soil samples were comparable with both ICP-OES & AHG-AAS and were found to be in excellent agreement.展开更多
Recent development in the use of the environmental radionuclide caesium-137 for documenting rates and soil redistribution on the cultivated or uncultivated land and estimating rates of sediment deposition on represent...Recent development in the use of the environmental radionuclide caesium-137 for documenting rates and soil redistribution on the cultivated or uncultivated land and estimating rates of sediment deposition on represents an important advance that overcomes many of the limitations of the conventional techniques commonly applied in such investigations. A study on soil redistribution （including soil erosion and deposition） was carried out in the Dian Lake catchment, Yunnan Province, using ^137Cs and selected chemical properties. The average soil erosion rate was 1,280.2 t km^2 yr^-1. Soil erosion rate occurring on different parts of the slope was significantly different on different parts of the slope, increasing.from the top. the bottom to the middle slope. The average soil erosion rate is also different with the land use type and that of the cultivated land （1, 672. 8 t km^-2 yr^-1） is higher than oJ the uncultivated land （1.161.2t km^-2 yr^-1 ）. The result shows that landform, slope gradient and land use type are key factors that influence the size of soil erosion. In addition, we also find the SOC and TN contents and amount of the soil erosion to be correlated in the soil. With the soil erosion occurring, there are land degradation and the local eco-environmental problems, such as water eutrophication in Dian Lake.展开更多
A new spectrofluorimetric reagent 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been synthesized and characterized through novel reaction techniques. A very simple, ultra-sensitive and highly selective non-extractive n...A new spectrofluorimetric reagent 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been synthesized and characterized through novel reaction techniques. A very simple, ultra-sensitive and highly selective non-extractive new spectrofluorimetric method for the determination of vanadium at Pico-trace levels using 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been developed. PTQA has been proposed as a new analytical reagent for the direct non-extractive spectrofluorimetric determination of vanadium (V). This novel fluorimetric reagent, PTQA becomes oxidized in a slightly acidic (0.0035 - 0.0085 M H2SO4) solution within vanadium (V) in 20% ethanol to produce highly fluorescent oxidized product (λex = 319 nm;λem = 371 nm). Constant and maximum fluorescence intensities were observed over a wide range of acidity (0.0035 - 0.0085 M H2SO4) for the period between 5 min and 24 h. Linear calibration graphs were obtained for 0.001 - 600-μg·L-1 of V, having a detection limit of 0.3-ng·L-1;the quantification limit of the reaction system was found to be 3-ng·L-1 and the RSD was 0% - 2%. A large excess of over 60 cations, anions and complexing agents (like, chloride, phosphate, azide, tartrate, oxalate, SCN- etc.) do not interfere in the determination. The developed method was successfully used in the determination of vanadium in several Certified Reference Materials (alloys, steels, serum, bovine liver, drinking water, soil and sediments) as well as in some environmental waters (potable and polluted), biological fluids (human blood, urine, hair and milk), soil samples and food samples (vegetables, rice and wheat) solutions containing both vanadium (IV) and vanadium (V) speciation and complex synthetic mixtures. The results of the proposed method for assessing biological, food and vegetable samples were comparable with inductively coupled plasma optical emission spectroscopy (ICP-OES) and atomic-absorption spectrophotometer (AAS) was found to be in excellent agreement.展开更多
基金Supported by a grant from the National R&D Program for Cancer Control,Ministry of Health and Welfare,Republic of Korea,No.HA20C0009.
文摘BACKGROUND Intrahepatic duct(IHD)stones are among the most important risk factors for cholangiocarcinoma(CCC).Approximately 10%of patients with IHD stones develop CCC;however,there are limited studies regarding the effect of IHD stone removal on CCC development.AIM To investigate the association between IHD stone removal and CCC development.METHODS We retrospectively analyzed 397 patients with IHD stones at a tertiary referral center between January 2011 and December 2020.RESULTS CCC occurred in 36 of the 397 enrolled patients.In univariate analysis,chronic hepatitis B infection(11.1%vs 3.0%,P=0.03),carbohydrate antigen 19-9(CA19-9,176.00 vs 11.96 II/mL,P=0.010),stone located in left or both lobes(86.1%vs 70.1%,P=0.042),focal atrophy(52.8%vs 26.9%,P=0.001),duct stricture(47.2%vs 24.9%,P=0.004),and removal status of IHD stone(33.3%vs 63.2%,P<0.001)were significantly different between IHD stone patients with and without CCC.In the multivariate analysis,CA19-9>upper normal limit,carcinoembryonic antigen>upper normal limit,stones located in the left or both lobes,focal atrophy,and complete removal of IHD stones without recurrence were independent factors influencing CCC development.However,the type of removal method was not associated with CCC risk.CONCLUSION Complete removal of IHD stones without recurrence could reduce CCC risk.
基金Project(41201492)supported by the National Natural Science Foundation of China
文摘A field investigation was performed to study the content, speciation and mobility of vanadium, as well as microbial response in soil from a stone coal smelting district in Hunan province of China. The results showed that the contents of soil V ranged from 168 to 1538 mg/kg, which exceeded the maximum permissible value of Canadian soil quality for V. The mean soil V content from wasteland area reached 1421 mg/kg, and those from the areas related with slag heap, ore pile and smelting center were 380, 260 and 225 mg/kg, respectively. Based on the results of the modified BCR sequential extraction procedure, V contents in the mobile fractions varied from 19.2 to 637 mg/kg accounting for 7.4%-42.3% of total V, and those of V(+5) species were between 21.9 and 534.0 mg/kg. Soil enzyme activity and microbial basal respiration were adversely affected by high level of soil V. More attention should be paid to soil V pollution and potential hazardous surrounding the stone coal smelting district.
基金Federal Highway Administration(FHWA)Under Grant No.DTFH61-98-C-0094
文摘The objective of this study is to develop an analytical methodology to evaluate the effectiveness of vibro stone column (S.C.) and dynamic compaction (D.C.) techniques supplemented with wick drains to densify and mitigate liquefaction in saturated sands and non-plastic silty soils. It includes the following: (i) develop numerical models to simulate and analyze soil densitication during S.C. installation and D.C. process, and (ii) identify parameters controlling post-improvement soil density in both cases, and (iii) develop design guidelines for densification of silty soils using the above techniques. An analytical procedure was developed and used to simulate soil response during S.C. and D.C. installations, and the results were compared with available case history data. Important construction design parameters and soil properties that affect the effectiveness of these techniques, and construction design choices suitable for sands and non-plastic silty soils were identified. The methodology is expected to advance the use of S.C. and D.C. in silty soils reducing the reliance on expensive field trials as a design tool. The ultimate outcome of this research will be design charts and design guidelines for using composite stone columns and composite dynamic compaction techniques in liquefaction mitigation of saturated silty soils.
文摘Level soil bunds (LSB) and stone bunds (SB) have been widely implemented in the Bokole watershed since 2000 through support of the World Food Program (WFP). However, the performance of them against the target of the structure has not been studied. This study analyzed the effect of LSB and SB on selected soil properties, when compared with nonterraced cropland. The Bokole watershed was divided into two units. From upper watershed, three croplands with LSB (aged 4, 6, and 9 years) and three nonterraced croplands each adjacent to one of the LSB were selected. Similarly, in lower watershed, SB aged 4, 6, and 8 years and three nonterraced croplands each adjacent to one of the SB were selected. From each cropland with LSB and SB, three composite soil samples (rep licates) were collected systematically in X designed rectangular plot. From each nonterraced cropland, three composite soil samples (replicates) were collected in X designed square plot. A total of 36 soil samples were analyzed for Soil Organic Carbon (SOC), Total Nitrogen (TN), Available Phosphorus (AP), Available Potassium (AK), pH, and Cation Exchange Capacity (CEC) following standard laboratory procedures. Most soil parameters were not significantly different in cropland with LSB and SB compared to nonterraced. However, in LSB aged 4 years and SB aged 6 years AP and pH were significantly less than their adjacent-nonterraced cropland. In SB aged 8 years, SOC, AP, AK, and pH were also significantly less than adjacent-nonterraced cropland. Past erosion, and past land uses are likely factors contributed to the observed result. It was inferred that the mean con tribution of LSB and SB alone for crop production with regard to analyzed soil parameters was not significant in the considered sites. Additional soil fertility management practices should be incorporated for better effect.
基金National Natural Science Foundation of China No.40071017+2 种基金 No.90202017 The Shilin Research Foundation of China No.199903
文摘Lunan stone forest is a kind of typical karst in China, which is mainly developed under red soil. In the winter of 1999, three study sites were chosen in stone forest national park according to vegetation cover, geomorphologic location and soil types. CO 2 concentration was measured with Gastec pump at different depths of soil (20, 40, 60 cm) and at the same time soil samples were gathered and soil properties such as soil moisture, pH, soil organic content were analyzed and the total number of viable microbes were counted in laboratory. In the study, dependent variable was chosen as the mean soil log (PCO 2 ), and soil properties were chosen as the independent variables. Multiple stepwise regression analysis showed that the total amount of microbes and soil moisture are the best indicators of the CO 2 production, with the equation LOG(PCO 2 ) = - 0.039(TNM) - 0.056(Mo) + 1.215 accounting for 86% of the variation of the soil CO 2 concentration, where TNM is the total number of microbes in the soil and Mo is the moisture of soil sample.
文摘Stone column is one of the soil stabilizing methods that is used to increase bearing capacity and decrease the settlement of soft soils.Reinforced and unreinforced granular blankets are now being utilized to overcome the problems of soft soils.In this research,the bearing capacity of stone columns,granular blanket,and a combination of both methods in reinforced and unreinforced modes were studied using scaled physical models.Results show that using granular blanket,stone column,and combination of both improves bearing capacity of soft soils.Using geogrid as the reinforcement of granular blankets and geotextile as stone-column encasement increases the efficiency of granular blankets and stone columns significantly.Additionally,in the case of using geotextile around the stone column,the stress concentration ratio of the stone column will increase as well as its rigidity and bearing capacity.
文摘This paper studies the motion of novel manipulator that can be used in the structure of stone protectors of soil tillage implements. According to the virtual reality technology-based method the technology of composition of the virtual model of a manipulator and its positions in the working process are described in details. This virtual model is used for composition the video clip, simulating the motion of novel manipulator, which three points are moving along two lines and one curve. The results obtained and the computer program realizing the virtual reality technology-based study of the working process of the virtual manipulators for stone protectors can be used by designers of stone protectors for soil tillage implements.
文摘A very simple, ultra-sensitive, highly selective and non-extractive new spectrofluorimetric method for the determination of arsenic at pico-trace levels using 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been developed. PTQA has been proposed as a new analytical reagent for the direct non-extractive spectrofluorimetric determination of Arsenic (V). This novel fluorimetric reagent, PTQA becomes oxidized in a slightly acidic (0.025 - 0.1 M H2SO4) solution with Arsenic (V) in absolute ethanol to produce highly fluorescent oxidized product (λex = 303 nm;λem = 365 nm). Constant and maximum fluorescence intensities were observed over a wide range of acidity (0.025 - 0.1 M H2SO4) for the period between 2 min and 24 h. Linear calibration graphs were obtained for 0.001 - 800-μgL-1 of As, having a detection limit of 0.1-ngL-1;the quantification limit of the reaction system was found to be 1-ngL-1 and the RSD was 0% - 2%. A large excess of over 60 cations, anions and complexion agents (like, chloride, phosphate, azide, tartrate, oxalate, SCN, etc.) do not interfere in the determination. The developed method was successfully used in the determination of arsenic in several Certified Reference Materials (alloys, steels, ores, human urine, hair, nails, bovine liver and sediments) as well as in some biological fluids (human blood, urine, hair, nail and milk), soil samples, food samples (vegetables, fruits, rice, corn and wheat), solutions containing both arsenic (III) and arsenic (V) speciation and complex synthetic mixtures. The results of the proposed method for assessing biological, food and soil samples were comparable with both ICP-OES & AHG-AAS and were found to be in excellent agreement.
基金sponsored by the fund on soil ero-sion and silt source of Dian Lake catchment (Grant No. 40473052).
文摘Recent development in the use of the environmental radionuclide caesium-137 for documenting rates and soil redistribution on the cultivated or uncultivated land and estimating rates of sediment deposition on represents an important advance that overcomes many of the limitations of the conventional techniques commonly applied in such investigations. A study on soil redistribution （including soil erosion and deposition） was carried out in the Dian Lake catchment, Yunnan Province, using ^137Cs and selected chemical properties. The average soil erosion rate was 1,280.2 t km^2 yr^-1. Soil erosion rate occurring on different parts of the slope was significantly different on different parts of the slope, increasing.from the top. the bottom to the middle slope. The average soil erosion rate is also different with the land use type and that of the cultivated land （1, 672. 8 t km^-2 yr^-1） is higher than oJ the uncultivated land （1.161.2t km^-2 yr^-1 ）. The result shows that landform, slope gradient and land use type are key factors that influence the size of soil erosion. In addition, we also find the SOC and TN contents and amount of the soil erosion to be correlated in the soil. With the soil erosion occurring, there are land degradation and the local eco-environmental problems, such as water eutrophication in Dian Lake.
文摘A new spectrofluorimetric reagent 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been synthesized and characterized through novel reaction techniques. A very simple, ultra-sensitive and highly selective non-extractive new spectrofluorimetric method for the determination of vanadium at Pico-trace levels using 2-(α-pyridyl)-thioquinaldinamide (PTQA) has been developed. PTQA has been proposed as a new analytical reagent for the direct non-extractive spectrofluorimetric determination of vanadium (V). This novel fluorimetric reagent, PTQA becomes oxidized in a slightly acidic (0.0035 - 0.0085 M H2SO4) solution within vanadium (V) in 20% ethanol to produce highly fluorescent oxidized product (λex = 319 nm;λem = 371 nm). Constant and maximum fluorescence intensities were observed over a wide range of acidity (0.0035 - 0.0085 M H2SO4) for the period between 5 min and 24 h. Linear calibration graphs were obtained for 0.001 - 600-μg·L-1 of V, having a detection limit of 0.3-ng·L-1;the quantification limit of the reaction system was found to be 3-ng·L-1 and the RSD was 0% - 2%. A large excess of over 60 cations, anions and complexing agents (like, chloride, phosphate, azide, tartrate, oxalate, SCN- etc.) do not interfere in the determination. The developed method was successfully used in the determination of vanadium in several Certified Reference Materials (alloys, steels, serum, bovine liver, drinking water, soil and sediments) as well as in some environmental waters (potable and polluted), biological fluids (human blood, urine, hair and milk), soil samples and food samples (vegetables, rice and wheat) solutions containing both vanadium (IV) and vanadium (V) speciation and complex synthetic mixtures. The results of the proposed method for assessing biological, food and vegetable samples were comparable with inductively coupled plasma optical emission spectroscopy (ICP-OES) and atomic-absorption spectrophotometer (AAS) was found to be in excellent agreement.
