An important area of research in nanotechnology deals with the synthesis of nanoparticles of different chemical compositions,sizes and controlled monodispersity.Currently,there is a growing need to develop environment...An important area of research in nanotechnology deals with the synthesis of nanoparticles of different chemical compositions,sizes and controlled monodispersity.Currently,there is a growing need to develop environmentally benign nanoparticle synthesis in which no toxic chemicals are used in the synthesis protocol.Palladium nanoparticles(Pd Np) are of interest because of their catalytic properties and affinity for hydrogen.Our protocol for the phyto-synthesis of Pd Np under moderate p H and room temperature offers a new means to develop environmentally benign nanoparticles.Solanum trilobatum is enlightened in our present study as it is enriched with phytochemicals to reduce palladium chloride ions.Poly MVA a dietary supplement based on the nontoxic chemotherapeutic lipoic acid-palladium complex(LA-Pd) is been hypothesized as the new paradigm of cancer therapy.Hence forth we successfully conjugated lipoic acid(S-Pd Np-LA) and vitamins(S-Pd Np-Vitamin-LA) to palladium nanoparticles synthesised from Solanum trilobatum leaf extract.These nanoparticles(S-Pd Np,S-Pd Np-LA,S-Pd Np-Vitamin-LA) were characterized with UV-Vis Spectroscopy,SEM and FTIR analysis,which revealed that S-Pd Np are polydisperse and of different morphologies ranging from 60?70 nm(S-Pd Np),65?80 nm(S-Pd Np-LA) and 75?100 nm(S-Pd Np-Vitamin-LA) in size.展开更多
Objective:To determine the larvicidal and pupicidal activites of Solanum trilobatum(S. trilobatum) leaf extracts against Aedes aegypti(Ae.aegypti),Culex quinquefasciatus(Cx. quinquefasciatus) and Anopheles stephensi(A...Objective:To determine the larvicidal and pupicidal activites of Solanum trilobatum(S. trilobatum) leaf extracts against Aedes aegypti(Ae.aegypti),Culex quinquefasciatus(Cx. quinquefasciatus) and Anopheles stephensi(An.stephensi).Methods:The larvicidal and pupucidal was determined at five different concentrations of 50,100,150,200 and 250 ppm.Percentage of larval mortality was assessed after 48 h.Results:Methanol extracts of S.trilobatum was found to be more susceptible against the larvae of Ae.aegypti.Cx.quinquefasciatus and An.stephensi at 250 ppm with a LC_(50) value of 125.43,127.77 and 116.64 ppm respectively.Leaf methanol extracts of S.trilobatum also exhibited pupicidal and adult emergence properties.Conclusions:These results suggested that the leaf extracts of S.Irilobalum showed potential to be used as an ideal ecofriendly approach for the control of the Ae.Aegypti,Cx.quinquefasciatus and An.stephensi.展开更多
文摘An important area of research in nanotechnology deals with the synthesis of nanoparticles of different chemical compositions,sizes and controlled monodispersity.Currently,there is a growing need to develop environmentally benign nanoparticle synthesis in which no toxic chemicals are used in the synthesis protocol.Palladium nanoparticles(Pd Np) are of interest because of their catalytic properties and affinity for hydrogen.Our protocol for the phyto-synthesis of Pd Np under moderate p H and room temperature offers a new means to develop environmentally benign nanoparticles.Solanum trilobatum is enlightened in our present study as it is enriched with phytochemicals to reduce palladium chloride ions.Poly MVA a dietary supplement based on the nontoxic chemotherapeutic lipoic acid-palladium complex(LA-Pd) is been hypothesized as the new paradigm of cancer therapy.Hence forth we successfully conjugated lipoic acid(S-Pd Np-LA) and vitamins(S-Pd Np-Vitamin-LA) to palladium nanoparticles synthesised from Solanum trilobatum leaf extract.These nanoparticles(S-Pd Np,S-Pd Np-LA,S-Pd Np-Vitamin-LA) were characterized with UV-Vis Spectroscopy,SEM and FTIR analysis,which revealed that S-Pd Np are polydisperse and of different morphologies ranging from 60?70 nm(S-Pd Np),65?80 nm(S-Pd Np-LA) and 75?100 nm(S-Pd Np-Vitamin-LA) in size.
基金supported by University Grant Commission(UGC)X plan(UGC/TN/GAC-2008)
文摘Objective:To determine the larvicidal and pupicidal activites of Solanum trilobatum(S. trilobatum) leaf extracts against Aedes aegypti(Ae.aegypti),Culex quinquefasciatus(Cx. quinquefasciatus) and Anopheles stephensi(An.stephensi).Methods:The larvicidal and pupucidal was determined at five different concentrations of 50,100,150,200 and 250 ppm.Percentage of larval mortality was assessed after 48 h.Results:Methanol extracts of S.trilobatum was found to be more susceptible against the larvae of Ae.aegypti.Cx.quinquefasciatus and An.stephensi at 250 ppm with a LC_(50) value of 125.43,127.77 and 116.64 ppm respectively.Leaf methanol extracts of S.trilobatum also exhibited pupicidal and adult emergence properties.Conclusions:These results suggested that the leaf extracts of S.Irilobalum showed potential to be used as an ideal ecofriendly approach for the control of the Ae.Aegypti,Cx.quinquefasciatus and An.stephensi.
