Failure criterion effect on solid production prediction and selection of completion solution

Production of fines together with reservoir fluid is called solid production. It varies from a few grams or less per ton of reservoir fluid posing only minor problems, to catastrophic amount possibly leading to erosion and complete filling of the borehole. This paper assesses solid production potential in a carbonate gas reservoir located in the south of Iran. Petrophysical logs obtained from the vertical well were employed to construct mechanical earth model. Then, two failure criteria, i.e. Mohre Coulomb and Mogi-Coulomb,were used to investigate the potential of solid production of the well in the initial and depleted conditions of the reservoir. Using these two criteria, we estimated critical collapse pressure and compared them to the reservoir pressure. Solid production occurs if collapse pressure is greater than pore pressure. Results indicate that the two failure criteria show different estimations of solid production potential of the studied reservoir. Mohre Coulomb failure criterion estimated solid production in both initial and depleted conditions, where Mogi-Coulomb criterion predicted no solid production in the initial condition of reservoir. Based on Mogi-Coulomb criterion, the well may not require completion solutions like perforated liner, until at least 60% of reservoir pressure was depleted which leads to decrease in operation cost and time.

Control strategy and methods for continuous direct compression processes

We presented a control strategy for tablet manufacturing processes based on continuous direct compression.The work was conducted by the experts of pharmaceutical companies,machine suppliers,academia,and regulatory authority in Japan.Among different items in the process,the component ratio and blended powder content were selected as the items requiring the control method specific to continuous manufacturing different from the conventional batch manufacturing.The control and management of the Loss in Weight(LIW)feeder were deemed the most important,and the Residence Time Distribution(RTD)model were regarded effective for setting the control range and for controlling of the LIW feeder.Based on these ideas,the concept of process control using RTD was summarized.

A comparative study of liquid and solid inner contact roxatidine acetate ion-selective electrode membranes

A comparative study was conducted using two designs of a roxatidine acetate （ROX）-selective electrode; a conventional liquid inner contact called electrode A and a graphite-coated solid contact called electrode 13. The fabrication of electrodes was based on roxatidine-tetraphenylborate （ROX-TPB） as an ion-association complex in a PVC matrix using different plasticizers. Electrode A has a linear dynamic range of 2.2 ×10^-5 mol/L to 1.0 ×10^-2 mol/L, with a Nernstian slope of 54.7 mV/decade and a detection limit of 1.4 ×10^-6 mol/L. Electrode B shows linearity over the concentration range of 1.0×10^-6 mol/L to 1.0×10^-2 tool/L, with a Nernstian slope of 51.2 mV/decade and a limit of detection of 1.1×10^7 mol/L which is remarkably improved as a result of diminishing ion fluxes in this solid contact, ion-selective electrode. The proposed sensors display useful analytical characteristics for the determination of ROX in bulk powder and its pharmaceutical formulation. The present electrodes show clear discrimination of ROX from several inorganic, organic ions, sugars, some common drug excipients and the degradation product （3-[3-（1-piperidinyl methyl） phenoxy] propyl amine） of ROX. Furthermore, the proposed electrodes were utilized for the determination of ROX in human plasma, where electrode B covers drug Cmax which indicated its applicability to pharmacokinetic, bioavailability and bioequivalent studies. The results obtained by the proposed electrodes were statistically analyzed and compared with those obtained by a reported HPLC method. No significant difference for either accuracy or precision was observed.

Solid Wood Products from Eucalypts Plantations

To improve and diversify the use of tropical plantation timbers in Southern China, with support from International Tropical Timber Organizations (ITTO), a research project was started in 2002 focusing on development of processing and manufacturing technologies to promote production of value-added wood products from eucalypts plantations. This project will also facilitate the formulation of forest management strategy in China to supplement the diminishing supply of timber from the natural forests. The sp...

Advanced Geometric Modeler with Hybrid Representation

An advanced geometric modeler GEMS4.0 has been developed, in whichfeature representation is used at the highest level abstraction of a productmodel. Boundary representation is used at the bottom level, while CSG modelis adopted at the median level. A BRep data structure capable of modelingnon-manifold is adopted. NURBS representation is used for all curved surfaces.Quadric surfaces have dual representations consisting of their geometric datasuch as radius, center point, and center tals. Boundary representation of freeform surfaces is easily built by sweeping and skinning method with NURBSgeometry Set operations on curved solids with boundary representation areperformed by an evaluation process consisting of four steps. A file exchangefacility is provided for the conversion between product data described by STEPand product information generated by GEMS4.0