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Metastatic pancreatic solitary fibrous tumor: A case report 被引量:1
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作者 Kiyoun Yi Jonghyun Lee Dong Uk Kim 《World Journal of Clinical Cases》 SCIE 2023年第35期8416-8424,共9页
BACKGROUND Solitary fibrous tumor(SFT)is a rare mesenchymal tumor that is most commonly found in the pleura but can also originate from non-pleural sites.Among the nonpleural localizations,the pancreas is extremely ra... BACKGROUND Solitary fibrous tumor(SFT)is a rare mesenchymal tumor that is most commonly found in the pleura but can also originate from non-pleural sites.Among the nonpleural localizations,the pancreas is extremely rare.In particular,metastasis to the pancreas from the central nervous system(CNS)is extremely rare,with only two cases reported so far.We report a case of recurrence in the pancreas 14 years after the initial complete surgical removal of a tumor in the CNS.CASE SUMMARY A 68-year-old man with a past medical history of recurrent meningeal hemangiopericytoma,currently referred to as SFT,presented to the hospital with jaundice.The patient was first diagnosed with an 8cm-sized meningeal hemangiopericytoma fourteen years ago and underwent osteoplastic craniotomy.After 16 mo,imaging showed recurrence and he underwent gamma knife radiosurgery(GKRS).2 years later,imaging showed recurrence again leading to a second GKRS.5 years later,recurrence was again suspected leading to a second craniotomy.Since then 3 years had passed,and imaging showed a 3.5cm-sized mass lesion on the pancreatic head with obstruction of the pancreatic and bile ducts.Endosonography with fine-needle aspiration biopsy was done preoperatively and aided in the diagnosis of SFT.The patient underwent pyloruspreserving pancreaticoduodenectomy.Pathologic findings of the resected pancreatic specimen,consistent with the previously resected brain specimen,confirmed the diagnosis of SFT.CONCLUSION The rarity and lack of knowledge about SFTs make suspecting and diagnosing this disease challenging.We believe that a report of metastatic pancreatic SFT from the CNS will contribute to a better understanding of this rare disease. 展开更多
关键词 solitary fibrous tumor hemangiopericytoma PANCREAS Metastasis Central nervous system Case report
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Chest Wall Hemangiopericytoma-Like Solitary Fibrous Tumor of the Pleura: Case Report with Computed Tomography Findings
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作者 Motohisa Kuwahara Hiroshi Nishimura +5 位作者 Masato Iwami Kazuya Naritomi Masae Mano Koji Inutsuka Keita Tokuishi Akinori Iwasaki 《Advances in Computed Tomography》 2013年第4期129-131,共3页
We present a case report of a 65-year-old woman who underwent resection of a chest wall tumor. In contrast with computed tomography, the tumor exhibited hypervascularity and was fed from the 9th intercostals artery. H... We present a case report of a 65-year-old woman who underwent resection of a chest wall tumor. In contrast with computed tomography, the tumor exhibited hypervascularity and was fed from the 9th intercostals artery. Histologically, the tumor was diagnosed as a cellular variant of solitary fibrous tumor of the pleura, with branching “staghorn” vessels and hypervascularity. The tumor thus resembled a chest wall hemangiopericytoma. 展开更多
关键词 solitarY fibrous tumor hemangiopericytoma Staghorn VESSELS
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Malignant solitary fibrous tumor of the greater omentum: A case report and review of literature 被引量:1
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作者 Yu-Chen Guo Li-Yu Yao +3 位作者 Zhi-Sen Tian Bing Shi Ying Liu Yuan-Yi Wang 《World Journal of Clinical Cases》 SCIE 2021年第2期445-456,共12页
BACKGROUND Malignant solitary fibrous tumors(SFTs)account for 15%-20%of all SFTs,and malignant SFTs arising from the greater omentum are extremely rare.Most malignant SFTs of the greater omentum are diagnosed via path... BACKGROUND Malignant solitary fibrous tumors(SFTs)account for 15%-20%of all SFTs,and malignant SFTs arising from the greater omentum are extremely rare.Most malignant SFTs of the greater omentum are diagnosed via pathological examinations after surgery.In this study,we report a case of malignant omental SFT and review the published literature on this rare malignancy.CASE SUMMARY A 64-year-old female presented with an abdominal mass,and underwent exploratory surgery,during which a huge tumor originating from the greater omentum and intraperitoneal implants were identified and resected.The results of the pathological examination,immunohistochemistry staining,and gene sequencing led to the diagnosis of malignant SFT of the greater omentum.The patient died one and a half years later due to tumor recurrence and metastasis.CONCLUSION This is the first report of the application of gene sequencing in the diagnosis of malignant SFTs of the greater omentum. 展开更多
关键词 solitary fibrous tumor Omentum malignancy Peritoneal implant hemangiopericytoma Gene sequence Case report
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Lipomatous hemangiopericytoma of the stomach:A case report and a review of literature 被引量:3
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作者 Hong-Biao Jing Qing-Da Meng Yan-Hong Tai 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第43期4835-4838,共4页
Lipomatous hemangiopericytomas(LHPCs) are rare soft-tissue tumors that are histologically characterized by hemangiopericytomatous vasculature and the presence of mature adipocytes.We present the clinicopathological fe... Lipomatous hemangiopericytomas(LHPCs) are rare soft-tissue tumors that are histologically characterized by hemangiopericytomatous vasculature and the presence of mature adipocytes.We present the clinicopathological features of a case of gastric LHPC in a 56-year-old female,along with a literature review.Endoscopy and endoscopic ultrasound showed a submucosal tumor 0.8 cm across in the greatest dimension in the lesser curvature side of the gastric antrum.Grossly,the well-defined mass had a solid and tan-white cut surface admixed with myxoid regions and yellowish areas.Histological examination revealed a submucosal well-circumscribed lesion composed of cellular nodules with the classic appearance of an hemangiopericytoma admixed with clusters and lobules of mature adipocytes.The ill-defined tumor cells had weakly eosinophilic cytoplasm and contained spindled nuclei with occasional small nucleoli.Nuclei atypia and mitoses were absent,and no cellular atypia,necrosis or vascular invasion was observed.Immunohistochemistry showed that the tumor cells were diffusely positive for CD34,CD99,and vimentin and were focally reactive for bcl-2.This is the first known report of an LHPC in the stomach.The patient was followed for 12 mo without any evidence of metastasis or recurrence. 展开更多
关键词 Lipomatous hemangiopericytoma hemangiopericytoma solitary fibrous tumor Stomach Immunohistochemistry
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Intracranial Hemangiopericytoma Focally Recurrent to the Pelvis
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作者 Robert Eil Kim C. Lu +1 位作者 George R. Wettach Vassiliki L. Tsikitis 《Journal of Cancer Therapy》 2012年第5期487-490,共4页
A 42-year-old male with a history of recurrent intracranial hemangiopericytoma presented to the Emergency Department with urinary retention. Ensuing work-up revealed a 10-centimeter circumscribed pelvic mass that appe... A 42-year-old male with a history of recurrent intracranial hemangiopericytoma presented to the Emergency Department with urinary retention. Ensuing work-up revealed a 10-centimeter circumscribed pelvic mass that appeared anatomically distinct from the sacrum. This metastasis was found 10 years after the initial resection of his intracranial lesion. An abdominal resection was performed, and the patient recovered uneventfully. Final pathology and staining findings were consistent with metastatic hemangiopericytoma. Hemangiopericytoma is a rare mesenchymal soft tissue neoplasm with potential for late local recurrence and metastasis. Here, we review the case and discuss the clinical relevance of narrowing the diagnosis to HPC or the growing umbrella of Solitary Fibrous Tumor (SFT). To our knowledge, this is the first report of intracranial HPC metastatic to the pelvis. 展开更多
关键词 hemangiopericytoma solitarY fibrous tumor INTRACRANIAL IMMUNOHISTOCHEMICAL METASTATIC
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Fat-forming variant of solitary fibrous tumor of the mediastinum 被引量:2
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作者 LIU Xi ZHANG Hong-ying BU Hong MENG Guo-zhao ZHANG Zhang KE Qi 《Chinese Medical Journal》 SCIE CAS CSCD 2007年第11期1029-1032,共4页
Fat-forming variant of solitary fibrous tumor (fat-forming variant of SFT), previously called lipomatous hemangiopericytoma (L-HPC), is a recently recognized rare variant of solitary fibrous tumor (SFT) with unp... Fat-forming variant of solitary fibrous tumor (fat-forming variant of SFT), previously called lipomatous hemangiopericytoma (L-HPC), is a recently recognized rare variant of solitary fibrous tumor (SFT) with unpredictable biologic behavior. Fat-forming variant of SFT occurs predominately in the deep soft tissues of the lower extremities. Histologically, it is composed of an admixture of benign hemangiopericytomatous and lipomatous components. Up to now, 展开更多
关键词 fat-forming variant of solitary fibrous tumor lipomatous hemangiopericytoma DNA ploidy differential diagnosis
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7例颅内孤立性纤维性肿瘤/血管周细胞瘤临床病理分析 被引量:3
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作者 刘祖平 郭庆喜 杨成万 《诊断病理学杂志》 2018年第10期714-717,720,共5页
目的 讨论颅内孤立性纤维性肿瘤/血管周细胞瘤(SFT/HPC)的临床病理学特征及鉴别诊断。方法 回顾分析7例颅内SFT/HPC临床及影像学特征、病理学特征及免疫表型。结果 本组病例中男性3例,女性4例,中位年龄52岁(38~59岁)。临床症状多为... 目的 讨论颅内孤立性纤维性肿瘤/血管周细胞瘤(SFT/HPC)的临床病理学特征及鉴别诊断。方法 回顾分析7例颅内SFT/HPC临床及影像学特征、病理学特征及免疫表型。结果 本组病例中男性3例,女性4例,中位年龄52岁(38~59岁)。临床症状多为头晕头痛、肢体麻木、颅内高压等;MRI/CT示与脑膜关系密切,为富于血供肿瘤,增强扫描呈明显强化。5例为WHOⅡ级,镜下见肿瘤细胞丰富,由梭形或多角形细胞构成,间质富含薄壁“鹿角状”血管及胶原纤维,瘤细胞围绕血管呈车幅状或同心圆样排列,核分裂象0~3个/10HPF;2例为WHOⅢ级,镜下见细胞密集,异型性明显,核分裂象8~10/10HPF。免疫组化结果示7例CD34、vimentin、STAT6(+)(7/7,100%),CD99(5/7,71.4%)及bcl-2(4/7,57.1%)部分(+),PR及EMA分别有1例(+),S-100、SMA均为(-),Ki-67(2%~10%)。随访13~87个月,2例患者术后复发,其中1例术后72个月复发并发生肺转移死亡。结论SFT/HPC为颅内罕见肿瘤,与脑膜关系密切,组织学形态多变,STAT6阳性可为特异性指标。应结合免疫组化、融合基因检测与脑膜瘤等鉴别。术后可复发转移,需长期随访。 展开更多
关键词 孤立性纤维性肿瘤/血管周细胞瘤 STAT6 临床病理分析
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Unusual occurrence of orbital hemangiopericytoma in the zygomatic bone of an adolescent: a case report 被引量:1
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作者 Bahram Eshraghi Hadi Ghadimi Zohreh Nozarian 《Eye and Vision》 SCIE 2018年第1期102-106,共5页
Background:Hemangiopericytoma and solitary fibrous tumor are considered related variants on the same spectrum and both may essentially be the same tumor.They are infrequently encountered in the orbital region while th... Background:Hemangiopericytoma and solitary fibrous tumor are considered related variants on the same spectrum and both may essentially be the same tumor.They are infrequently encountered in the orbital region while the zygomatic bone is an extremely rare location for these neoplasms to occur.Case presentation:A 14-year-old boy presented with complaint of deformity of left infraorbital area and a firm,regular mass in the region.Orbital CT scan revealed a well-defined round isodense intraosseous lesion in the lowermost portion of the lateral orbital wall(zygomatic bone),expanding the bone and protruding anteriorly and medially.MRI showed the mass to be heterogenous and strongly enhancing with contrast medium.Inferior transconjunctival orbitotomy was performed and the mass was removed.The histopathologic examination and immunohistochemistry staining results(positive for CD34,CD31 and smooth muscle actin,but negative for CD99,S100,B-cell lymphoma 2(bcl-2)and desmin)confirmed the diagnosis of hemangiopericytoma.The postoperative course was uneventful,with no evidence of recurrence after 5 years follow up.Conclusions:This case represents the second hemangiopericytoma reported in the zygomatic bone.Although extremely rare,hemangiopericytoma/solitary fibrous tumor might be considered in the differential diagnosis of intraosseous lesions of the orbital and zygomatic region. 展开更多
关键词 hemangiopericytoma Orbital neoplasm solitary fibrous tumor Zygomatic bone
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