Benzyltriphenylphosphonium tribromide(BTPTB) has been applied as an efficient catalyst for the preparation of bis(indolyl)-methanes (BIMs) via electrophilic substitution of indoles with aldehydes in the absence ...Benzyltriphenylphosphonium tribromide(BTPTB) has been applied as an efficient catalyst for the preparation of bis(indolyl)-methanes (BIMs) via electrophilic substitution of indoles with aldehydes in the absence of solvent.展开更多
A variety of alcohols and phenols are efficiently acetylated with acetic anhydride in the presence of a catalytic amount of V(HSO4)3 in solution and under solvent free conditions. Mild reaction conditions, high yiel...A variety of alcohols and phenols are efficiently acetylated with acetic anhydride in the presence of a catalytic amount of V(HSO4)3 in solution and under solvent free conditions. Mild reaction conditions, high yields of the products, easy procedure and selective acetylation of alcohols and phenols in the presence of amines and thiols are the main advantages of this procedure.展开更多
Strontium chloride was used as an efficient and recyclable catalyst in one-pot condensation of anthranilic acid, ortho esters and amines leading to the formation of 4(3H)-quinazolinone derivatives in good yields at ...Strontium chloride was used as an efficient and recyclable catalyst in one-pot condensation of anthranilic acid, ortho esters and amines leading to the formation of 4(3H)-quinazolinone derivatives in good yields at room temperature under solvent-free conditions.展开更多
A simple and convenient procedure for the preparation of amines from aldehydes and ketones with sodium borohydride activated by silica chloride as a catalyst under solvent-free conditions is described.A variety of ali...A simple and convenient procedure for the preparation of amines from aldehydes and ketones with sodium borohydride activated by silica chloride as a catalyst under solvent-free conditions is described.A variety of aliphatic and aromatic aldehydes,ketones and amines when mixed with NaBH;/silica chloride at room temperature,afforded excellent yield of the corresponding amines.展开更多
A Yb(OTf)3-catalyzed approach for the synthesis of pyrroles under solvent-free conditions was achieved, which could afford the desired products with yields ranged from moderate to excellent.
Fluoroboric acid adsorbed on silica-gel(HBF4·SiO2) has been found to be an extremely efficient and recyclable catalyst for the preparation of β-enaminones and β-enamino esters under solvent-free conditions.
β-Amino esters were synthesized via ZnCl2-catalyzed Mannich-type reaction of imines and malonate esters under solvent-free conditions in 6 min. The β-amino ester was converted into the corresponding aspartic acid de...β-Amino esters were synthesized via ZnCl2-catalyzed Mannich-type reaction of imines and malonate esters under solvent-free conditions in 6 min. The β-amino ester was converted into the corresponding aspartic acid derivatives.展开更多
A simple and efficient procedure for the preparation of aryl- 14-H-dibenzo [aj]xanthenes by a one-pot condensation reaction of 2-naphthol and aryl aldehydes, in the presence of silica supported sodium hydrogen sulfate...A simple and efficient procedure for the preparation of aryl- 14-H-dibenzo [aj]xanthenes by a one-pot condensation reaction of 2-naphthol and aryl aldehydes, in the presence of silica supported sodium hydrogen sulfate (NaHSO4/SiO2) as a catalyst and in the absence of solvent has been developed. The present method offers several advantages such as excellent yields, short reaction time (10-30min), mild condition, simple work-up, and the use of a cheap and environmentally friendly catalyst with remarkable reusability.展开更多
Sodium dihydrogen phosphate (NaH2PO4) efficiently catalyzes the condensation reaction of benzil, aldehydes, amines and ammonium acetate in a four-component reaction under solvent-free conditions. The reaction procee...Sodium dihydrogen phosphate (NaH2PO4) efficiently catalyzes the condensation reaction of benzil, aldehydes, amines and ammonium acetate in a four-component reaction under solvent-free conditions. The reaction proceeds rapidly and affords the corresponding tetra-substituted imidazoles in high yields. Also an efficient route was developed for the synthesis of tri-substituted imidazoles from condensation of benzil, aldehydes and ammonium acetate using NaH2PO4.展开更多
Boric acid efficiently catalysed the one-pot reaction of alkyl or aryl aldehydes with 2-naphthol to afford the corresponding 14- alkyl-or aryl-14H-dibenzo[a,j]xanthenes in good yields under solvent-free conditions.
A new convenient and environmentally benign procedure for synthesis of azines from hydrazme sulfate with several aromatic aldehydes coupled with grinding is studied. This reaction is carried out under solvent-free con...A new convenient and environmentally benign procedure for synthesis of azines from hydrazme sulfate with several aromatic aldehydes coupled with grinding is studied. This reaction is carried out under solvent-free conditions and in absence of catalyst to afford high yields of relevant azines.展开更多
A new series of 3-cyano-2-pyridones derivatives have been prepared by reaction of enaminonitriles with pri-mary amine under solvent free condition. This procedure have the advantage of high yields and being environ-me...A new series of 3-cyano-2-pyridones derivatives have been prepared by reaction of enaminonitriles with pri-mary amine under solvent free condition. This procedure have the advantage of high yields and being environ-mentally-friendly.展开更多
A simple and efficient solvent-free method was developed for the acetylation of alcohols, phenols and amines in excellent yields employing glycerol-based sulfonic acid (-SO3H) functionalized carbon catalyst under envi...A simple and efficient solvent-free method was developed for the acetylation of alcohols, phenols and amines in excellent yields employing glycerol-based sulfonic acid (-SO3H) functionalized carbon catalyst under environmentally benign reaction conditions. The salient features of this protocol are the short reaction time, ease of product isolation and reusability of the carbon catalyst.展开更多
An efficient procedure for the preparation of 1-substituted-1H-1,2,3,4-tetrazoles via a three-component condensation of triethyl orthoformate, amine, and trimethylsilyl azide using inexpensive and environment-friendly...An efficient procedure for the preparation of 1-substituted-1H-1,2,3,4-tetrazoles via a three-component condensation of triethyl orthoformate, amine, and trimethylsilyl azide using inexpensive and environment-friendly FeCl3 as catalyst under solvent-free conditions has been reported. The reaction generates the corresponding 1-substituted tetrazole in excellent yields.展开更多
The catalytic alcohol dehydrogenation to carboxylic acids has been demonstrated as an atom-economic and environmental-friendly synthetic method.However,the reported catalysts either require relatively complicated synt...The catalytic alcohol dehydrogenation to carboxylic acids has been demonstrated as an atom-economic and environmental-friendly synthetic method.However,the reported catalysts either require relatively complicated synthesis or exhibit high activity only in the presence of a solvent.Therefore,it is still in high demand to obtain catalysts that feature facile synthesis and perform well even without any solvent.Herein,a series of nanostructured bimetallic Zn/Co species embedded in N-doped hierarchical porous carbon were fabricated in a facile and green manner.More significantly,the best-performing material(Zn/Co@NC-800)was identified as the first heterogeneous catalyst to enable this transformation under solvent-free conditions.Moreover,the as-prepared composites were comprehensively investigated to de-termine their structural and morphological properties,which rationalized the superiority of Zn/Co@NC-800 over the other synthesized materials.Further studies signified that Co sites(both Co^(0)and Co^(2+))and N species(mainly pyridinic N)were probably involved in this process,functioning as the Lewis acid site and basic site,respectively.Hopefully,this study could provide a simple and sustainable method for carboxylic acid synthesis.展开更多
In this study, 1,3-disulfonic acid imidazolium hydrogen sulfate (DSIMHS) is used as an efficient and reusable ionic liquid for the green, mild, and efficient synthesis of xanthenes under solvent-free conditions. Sim...In this study, 1,3-disulfonic acid imidazolium hydrogen sulfate (DSIMHS) is used as an efficient and reusable ionic liquid for the green, mild, and efficient synthesis of xanthenes under solvent-free conditions. Simple and easy work-up, low cost, green process, short reaction times and excellent yields of the products are the advantages of this procedure. Further, the catalyst can be recycled and reused at least for four times without a noticeably decrease in its catalytic activity.展开更多
Pentafluorophenylammonium triflate(PFPAT) was found to be a highly efficient catalyst for the preparation of 2,4,6- triarylpyridines from the reaction of acetophenone derivatives,aromatic aldehydes and ammonium acet...Pentafluorophenylammonium triflate(PFPAT) was found to be a highly efficient catalyst for the preparation of 2,4,6- triarylpyridines from the reaction of acetophenone derivatives,aromatic aldehydes and ammonium acetate.Present methodology offers several advantages,such as short reaction time,high yields,simple procedure with an easy work-up and the absence of any volatile and hazardous organic solvent.In addition,this catalytic system can act as an active,inexpensive,metal-free,recoverable and recyclable catalyst.展开更多
A new polymeric reagent, cross-linked poly(4-vinylpyridine) supported azide ion, [P4-VP]N3, was introduced as polymeric reagents for efficient and regioselective conversion of epoxides to azidohydrins in the presenc...A new polymeric reagent, cross-linked poly(4-vinylpyridine) supported azide ion, [P4-VP]N3, was introduced as polymeric reagents for efficient and regioselective conversion of epoxides to azidohydrins in the presence of cross-linked poly(4-vinylpyridine) supported sulfuric acid, [P4-VP]H2SO4, as a solid proton source and as catalyst under solvent-free conditions. The advantages of this polymeric reagent over some of those reported in the literature are easy work-up procedure and regeneration of the reagent.展开更多
An efficient and simple procedure for the synthesis of novel isatin derivatives is described. Michael addition of aniline Schiff bases of isatin or p-toluidine Schiff bases of isatin to fumaric esters affords the Mich...An efficient and simple procedure for the synthesis of novel isatin derivatives is described. Michael addition of aniline Schiff bases of isatin or p-toluidine Schiff bases of isatin to fumaric esters affords the Michael adduct com- pounds in good to high yields in the presence of K2CO3 and tetrabutylammonium bromide (TBAB) under sol- vent-free conditions. Repeating of this reaction about spiro[l,3-dioxolane-2,3'-indol]-2'(l'H)-one, as a Michael do- nor, in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) gives Michael adducts in remarkable yields under the same conditions.展开更多
文摘Benzyltriphenylphosphonium tribromide(BTPTB) has been applied as an efficient catalyst for the preparation of bis(indolyl)-methanes (BIMs) via electrophilic substitution of indoles with aldehydes in the absence of solvent.
基金this work by the research affair,University of Guilan,Rasht,Iran,
文摘A variety of alcohols and phenols are efficiently acetylated with acetic anhydride in the presence of a catalytic amount of V(HSO4)3 in solution and under solvent free conditions. Mild reaction conditions, high yields of the products, easy procedure and selective acetylation of alcohols and phenols in the presence of amines and thiols are the main advantages of this procedure.
文摘Strontium chloride was used as an efficient and recyclable catalyst in one-pot condensation of anthranilic acid, ortho esters and amines leading to the formation of 4(3H)-quinazolinone derivatives in good yields at room temperature under solvent-free conditions.
基金support of this work from the Research Council of Mazandaran University gratefully acknowledged.
文摘A simple and convenient procedure for the preparation of amines from aldehydes and ketones with sodium borohydride activated by silica chloride as a catalyst under solvent-free conditions is described.A variety of aliphatic and aromatic aldehydes,ketones and amines when mixed with NaBH;/silica chloride at room temperature,afforded excellent yield of the corresponding amines.
基金the National Key Technology R&D Program(No.2007BAI34B00)the National Natural Science Foundation of China(No.20876147 and 20676123)the Natural Science Foundation of Zhejiang Province(No.Y4080107) for financial support.
文摘A Yb(OTf)3-catalyzed approach for the synthesis of pyrroles under solvent-free conditions was achieved, which could afford the desired products with yields ranged from moderate to excellent.
文摘Fluoroboric acid adsorbed on silica-gel(HBF4·SiO2) has been found to be an extremely efficient and recyclable catalyst for the preparation of β-enaminones and β-enamino esters under solvent-free conditions.
基金the financial support form National Natural Science Foundation of China(No.20472116).
文摘β-Amino esters were synthesized via ZnCl2-catalyzed Mannich-type reaction of imines and malonate esters under solvent-free conditions in 6 min. The β-amino ester was converted into the corresponding aspartic acid derivatives.
基金the K.N.Toosi University of Technology Research Council for financial support.
文摘A simple and efficient procedure for the preparation of aryl- 14-H-dibenzo [aj]xanthenes by a one-pot condensation reaction of 2-naphthol and aryl aldehydes, in the presence of silica supported sodium hydrogen sulfate (NaHSO4/SiO2) as a catalyst and in the absence of solvent has been developed. The present method offers several advantages such as excellent yields, short reaction time (10-30min), mild condition, simple work-up, and the use of a cheap and environmentally friendly catalyst with remarkable reusability.
文摘Sodium dihydrogen phosphate (NaH2PO4) efficiently catalyzes the condensation reaction of benzil, aldehydes, amines and ammonium acetate in a four-component reaction under solvent-free conditions. The reaction proceeds rapidly and affords the corresponding tetra-substituted imidazoles in high yields. Also an efficient route was developed for the synthesis of tri-substituted imidazoles from condensation of benzil, aldehydes and ammonium acetate using NaH2PO4.
文摘Boric acid efficiently catalysed the one-pot reaction of alkyl or aryl aldehydes with 2-naphthol to afford the corresponding 14- alkyl-or aryl-14H-dibenzo[a,j]xanthenes in good yields under solvent-free conditions.
文摘A new convenient and environmentally benign procedure for synthesis of azines from hydrazme sulfate with several aromatic aldehydes coupled with grinding is studied. This reaction is carried out under solvent-free conditions and in absence of catalyst to afford high yields of relevant azines.
文摘A new series of 3-cyano-2-pyridones derivatives have been prepared by reaction of enaminonitriles with pri-mary amine under solvent free condition. This procedure have the advantage of high yields and being environ-mentally-friendly.
文摘A simple and efficient solvent-free method was developed for the acetylation of alcohols, phenols and amines in excellent yields employing glycerol-based sulfonic acid (-SO3H) functionalized carbon catalyst under environmentally benign reaction conditions. The salient features of this protocol are the short reaction time, ease of product isolation and reusability of the carbon catalyst.
文摘An efficient procedure for the preparation of 1-substituted-1H-1,2,3,4-tetrazoles via a three-component condensation of triethyl orthoformate, amine, and trimethylsilyl azide using inexpensive and environment-friendly FeCl3 as catalyst under solvent-free conditions has been reported. The reaction generates the corresponding 1-substituted tetrazole in excellent yields.
基金This work was financially supported by the Natural Science Foundation of Hubei Province(No.2022CFB388)the fund of the Key Laboratory of Catalysis and Energy Materials Chemistry of the Ministry of Education&Hubei Key Laboratory of Catalysis and Ma-terials Science(No.CHCL19002)+1 种基金the State Key Laboratory of Ad-vanced Technology for Materials Synthesis and Processing(Wuhan University of Technology,No.2021-KF-19)the National Natural Science Foundation of China(No.22102127).We would also like to thank eceshi(www.eceshi.com)for the TPD tests.
文摘The catalytic alcohol dehydrogenation to carboxylic acids has been demonstrated as an atom-economic and environmental-friendly synthetic method.However,the reported catalysts either require relatively complicated synthesis or exhibit high activity only in the presence of a solvent.Therefore,it is still in high demand to obtain catalysts that feature facile synthesis and perform well even without any solvent.Herein,a series of nanostructured bimetallic Zn/Co species embedded in N-doped hierarchical porous carbon were fabricated in a facile and green manner.More significantly,the best-performing material(Zn/Co@NC-800)was identified as the first heterogeneous catalyst to enable this transformation under solvent-free conditions.Moreover,the as-prepared composites were comprehensively investigated to de-termine their structural and morphological properties,which rationalized the superiority of Zn/Co@NC-800 over the other synthesized materials.Further studies signified that Co sites(both Co^(0)and Co^(2+))and N species(mainly pyridinic N)were probably involved in this process,functioning as the Lewis acid site and basic site,respectively.Hopefully,this study could provide a simple and sustainable method for carboxylic acid synthesis.
基金the University of Guilan Research Council for the partial support
文摘In this study, 1,3-disulfonic acid imidazolium hydrogen sulfate (DSIMHS) is used as an efficient and reusable ionic liquid for the green, mild, and efficient synthesis of xanthenes under solvent-free conditions. Simple and easy work-up, low cost, green process, short reaction times and excellent yields of the products are the advantages of this procedure. Further, the catalyst can be recycled and reused at least for four times without a noticeably decrease in its catalytic activity.
基金supported by the Islamic Azad University,Tonekabon Branch
文摘Pentafluorophenylammonium triflate(PFPAT) was found to be a highly efficient catalyst for the preparation of 2,4,6- triarylpyridines from the reaction of acetophenone derivatives,aromatic aldehydes and ammonium acetate.Present methodology offers several advantages,such as short reaction time,high yields,simple procedure with an easy work-up and the absence of any volatile and hazardous organic solvent.In addition,this catalytic system can act as an active,inexpensive,metal-free,recoverable and recyclable catalyst.
文摘A new polymeric reagent, cross-linked poly(4-vinylpyridine) supported azide ion, [P4-VP]N3, was introduced as polymeric reagents for efficient and regioselective conversion of epoxides to azidohydrins in the presence of cross-linked poly(4-vinylpyridine) supported sulfuric acid, [P4-VP]H2SO4, as a solid proton source and as catalyst under solvent-free conditions. The advantages of this polymeric reagent over some of those reported in the literature are easy work-up procedure and regeneration of the reagent.
文摘An efficient and simple procedure for the synthesis of novel isatin derivatives is described. Michael addition of aniline Schiff bases of isatin or p-toluidine Schiff bases of isatin to fumaric esters affords the Michael adduct com- pounds in good to high yields in the presence of K2CO3 and tetrabutylammonium bromide (TBAB) under sol- vent-free conditions. Repeating of this reaction about spiro[l,3-dioxolane-2,3'-indol]-2'(l'H)-one, as a Michael do- nor, in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) gives Michael adducts in remarkable yields under the same conditions.