Utility of geochemistry in mineral exploration is known since more than half-a-century.In reconnaissance diamond exploration,regolith geochemistry is a well known tool worldwide and helps in distinguishing
The dykes intruding the Hyderabad Granitic Region(HGR)which forms the part of eastern Dharwar Craton extending between northern and northwestern margins of the Cuddapah Basin and western margin of the
The objective of this article is to develop a groundwater flow model for a tannery belt using Visual MOD-FLOW Premium 4.4 for analyzing groundwater velocity and its response to various pumping strategies in two stages...The objective of this article is to develop a groundwater flow model for a tannery belt using Visual MOD-FLOW Premium 4.4 for analyzing groundwater velocity and its response to various pumping strategies in two stages, viz., steady and transient conditions. The steady state model was calibrated for April 2001, whereas the transient model was employed to forecast groundwater flow under various pumping strategies. The results showed that the total groundwater abstraction was about 80.43% of the groundwater recharge, but 10.25% was used up by evapotranspiration. The groundwater velocity, which is important for contaminant migration, varied from 0.21 to 0.52 m/d in the tannery cluster. The model was more sensitive to recharge from rainfall, hydraulic conductivity and specific yield. Finally, the model showed that the aquifer could sustain a pumping rate of 24892 m3/day without further decline in water level.展开更多
Background:Leber congenital amaurosis(LCA),primarily characterized by retinal degeneration is the most severe form of inherited retinal dystrophy(IRD)responsible for congenital blindness.The presence of phenotypic het...Background:Leber congenital amaurosis(LCA),primarily characterized by retinal degeneration is the most severe form of inherited retinal dystrophy(IRD)responsible for congenital blindness.The presence of phenotypic heterogeneity makes the diagnosis of LCA challenging,especially in the absence of pronounced disease pathognomonic,yet it can be well comprehended by employing molecular diagnosis.Therefore,the present study aimed to reveal the causative mutations in ten LCA patients with variable phenotypes using clinical exome sequencing(CES).Methods:CES was performed in ten unrelated LCA patients.Ophthalmic information and family history of all patients were obtained to make a meaningful interpretation.The clinical exome data was analyzed and prioritized using a bioinformatics pipeline to identify mutations,which was further validated by Sanger sequencing.Segregation analysis was also performed on available family members.Results:CES led to the identification of causative mutations in nine LCA patients.Seven patients harbored a mutation in six LCA candidate genes,including RPE65,LCA5(n=2),CRX,PRPH2,CEP290,and ALMS1,while two patients possess a mutation in IFT80 and RP1,known to cause other diseases.Three novel mutations in LCA5(c.1823del),CRX(c.848del)and CEP290(c.2483G>T)were identified.The current study reports for the first time,a mutation in PRPH2,CEP290,and ALMS1 from the Indian population.Additionally,we observed a novel association of LCA phenotype with IFT80 known to cause Jeune syndrome.Based on the genetic finding,the patient AS09,who harbored a mutation in the RP1 gene,was re-diagnosed with early-onset retinitis pigmentosa.Conclusion:In conclusion,the results underline the importance of CES in clinically diagnosed LCA patients with variable phenotypes.The correlation between mutations in candidate genes and clinical phenotypes,helps to refine the clinical diagnosis.However,molecular evaluation with a larger cohort of LCA patients is needed for better understanding of the mutational spectrum in southern India.展开更多
This is a new report on the early Eocene radiolarian fauna from the Sangdanlin section in the Gyirong region, along the southern margin of the Yarlung Zangbo Suture Zone. The Sangdanlin section measured in this study ...This is a new report on the early Eocene radiolarian fauna from the Sangdanlin section in the Gyirong region, along the southern margin of the Yarlung Zangbo Suture Zone. The Sangdanlin section measured in this study is divided into three lithostratigraphic units from bottom to top: the Zongzhuo, Sangdanlin, and Zheya formations. Abundant radiolarian fossils were obtained from the Sangdanlin section and 54 species of 30 genera were identified and assigned as follows: Cryptamphorella conara-C. macropora the late Cretaceous Zone and Amphisphaera coronate, Buryella tetradica-Bekoma campechensis, and B.bidartensis-B. divaricata the Paleocene-early Eocene Interval Zones. The Paleocene–early Eocene radiolarian zones are comparable to the radiolarian zones RP4-RP8 in New Zealand. Based on the data of radiolaria and lithofacies, it is suggested that the Zongzhuo Formation should be deposited along the base of the north-facing, continental slope of the Greater Indian continental margin, and the Sangdanlin Formation should be a deep marine, sedimentary sequence located in a foreland basin. The early Eocene radiolarian fauna in the Sangdanlin Formation constrains the initial age of the India-Asia collision to no later than 53.6 Ma.展开更多
The complexities in the relationship between winter monsoon rainfall (WMR) over South India and Sea Surface temperature (SST) variability in the southern and tropical Indian Ocean (STIO) are evaluated statistically. T...The complexities in the relationship between winter monsoon rainfall (WMR) over South India and Sea Surface temperature (SST) variability in the southern and tropical Indian Ocean (STIO) are evaluated statistically. The data of the time period of our study (1950-2003) have been divided exactly in two halves to identify predictors. Correlation analysis is done to see the effect of STIO SST variability on winter monsoon rainfall index (WMRI) for South India with a lead-lag of 8 seasons (two years). The significant positive correlation is found between Southern Indian Ocean (SIO) SST and WMRI in July-August-September season having a lag of one season. The SST of the SIO, Bay of Bengal and North Equatorial Indian Ocean are negatively correlated with WMRI at five, six and seven seasons before the onset of winter monsoon. The maximum positive correlation of 0.61 is found from the region south of 500 S having a lag of one season and the negative correlations of 0.60, 0.53 and 0.57 are found with the SST of the regions SIO, Bay of Bengal and North Equatorial Ocean having lags of five, six and seven seasons respectively and these correlation coefficients have confidence level of 99%. Based on the correlation analysis, we defined Antarctic Circumpolar Current Index A and B (ACCIA (A) & ACCIB (B)), Bay of Bengal index (BOBI (C)) and North Equatorial Index (NEI (D)) by averageing SST for the regions having maximum correlation (positive or negative) with WMRI index. These SST indices are used to predict the WMRI using linear and multivariate linear regression models. In addition, we also attempted to detect a dynamic link for the predictability of WMRI using Nino 3.4 index. The predictive skill of these indices is tested by error analysis and Willmott’s index.展开更多
The pre-collisional southern margin of Asia can be restored using paleomagnetic data from late Cretaceous rocks from the Lhasa terrane.However,the available data are based either on the red beds or on the intercalated...The pre-collisional southern margin of Asia can be restored using paleomagnetic data from late Cretaceous rocks from the Lhasa terrane.However,the available data are based either on the red beds or on the intercalated thin layers of lava flows,both of which had been involved in strongly folding.Recent studies show clear evidence for the possibility of serious overprint hence the data could not be reliably used for tectonic interpretation.We report paleomagnetic data from diorite dykes and the grano-diorite country rock in the Gandise belt near the city of Lhasa.U–Pb isotopic dating indicates the intrusive rocks have an age of^82–86 Ma.Fifteen sites yield acceptable Ch RM directions which pass a reversal test.SEM and light microscope observations show primaryintergrowth relationship between magnetite and other minerals within the thin sections.AMS measurement defines a primary magma flow fabric for the intruded dykes and the country rocks.All the characteristics support that the Ch RMs are primary.The paleomagnetic pole calculated from the remanence of the dykes and the country rocks yields a paleolatitude of^14°N which provide a reliable constraint for the southern margin of Asia near Lhasa.Furthermore,the recorded declination shows significant counterclockwise rotation of^20°for the sampling location relative to the north.In consideration of the strike and tectonic setting of the dykes,the strike of the southern margin of Asia is restored which is compatible with the hypothesis of a quasi-linear margin of Eurasia prior to its collision with India.展开更多
The Indian summer monsoon exhibits considerable spatio-temporal variability.It is therefore important to understand its dynamics and the inherent periodicities.In this study,we have performed spectral and wavelet anal...The Indian summer monsoon exhibits considerable spatio-temporal variability.It is therefore important to understand its dynamics and the inherent periodicities.In this study,we have performed spectral and wavelet analyses of magnetic susceptibility data for sediments from Thimmannanayakanakere(TK)-a small lake in southern India.The main objective of this investigation is to identify and explain the possible origin of the prominent periodicities present in the magnetic susceptibility data.Significant periodicities in the TK χ_(lf)data are centered at 906,232,147,128,96,61,54 and 44 years,which might have a solar origin.The wavelet power spectrum of the raw and detrended χ_(lf)data confirms the findings of spectral analysis and also provides temporal variations of the significant cyclicities during the past3700 cal.years B.P.Positive correlation is documented between sunspot activity and TK xif data;crossspectral analysis of the reconstructed sunspot data and TK xif data suggest that there is a strong coherence between the two datasets as significant periodicities are documented in both.There is a good match between the TK xif and the reconstructed total solar irradiance data for the past 1200 years.However,an out-of-phase relationship is documented at certain time-intervals,which may be attributed to uncertainties in the age-depth model.The results obtained from this study show that solar variations are the main controlling factor of the southwest monsoon and,like other archives from different regions in India,the TK lake sediments have also recorded these solar signatures.展开更多
Melioidosis,a disease of public health importance in Southeast Asia and Northern Australia,of late has shown an increasing trend in India,particularly Southern India.We describe a ease of a 39-year-old diabetic patien...Melioidosis,a disease of public health importance in Southeast Asia and Northern Australia,of late has shown an increasing trend in India,particularly Southern India.We describe a ease of a 39-year-old diabetic patient with left elbow septic arthritis,multiple liver,splenic abscesses, pneumonia,pleural effusion,followed by sepsis syndrome.Blood cultures and culture of the joint aspirate yielded pure growth of Burkholderia psettdomallei(B.pesudomallei),sensitive to carbapenem,co-trimoxazole and resistant to ceftazidime.The patient was successfully treated with imipenem- cilastin.He was discharged on co-trimoxazole to complete the 24 weeks course and follow-up has continued to date.The patient continues to remain asymptomatic.The case re-emphasizes the need to monitor the trend of B.pseudomallei in India,particularly the development of ceftazidime resistance,which incidentally is the drug of choice.展开更多
An extreme rainstorm hit southern China during 13–17 December 2013, with a record-breaking daily rainfall rate, large spatial extent, and unusually long persistence. We examined what induced this heavy rainfall proce...An extreme rainstorm hit southern China during 13–17 December 2013, with a record-breaking daily rainfall rate, large spatial extent, and unusually long persistence. We examined what induced this heavy rainfall process, based on observed rainfall data and NCEP–NCAR reanalysis data through composite and diagnostic methods. The results showed that a Rossby waveguide within the subtropical westerly jet caused the event. The Rossby wave originated from strong cold air intrusion into the subtropical westerly jet over the eastern Mediterranean. With the enhancement and northward shift of the Middle East westerly jet, the Rossby wave propagated slowly eastward and deepened the India–Burma trough, which transported a large amount of moisture from the Bay of Bengal and South China Sea to southern China. Strong divergence in the upper troposphere, caused by the enhancement of the East Asian westerly jet, also favored the heavy rainfall process over Southeast China. In addition, the Rossby wave was associated with a negative-to-positive phase shift and enhancement of the North Atlantic Oscillation, but convergence in the eastern Mediterranean played the key role in the eastward propagation of the Rossby wave within the subtropical westerly jet.展开更多
This is an extended abstract of Hu et al.,2012. The timing of the initial collision between India and Asia remains a matter of considerable debate,with views ranging from~70 Ma to~35 Ma.Here the initial India-Asia c...This is an extended abstract of Hu et al.,2012. The timing of the initial collision between India and Asia remains a matter of considerable debate,with views ranging from~70 Ma to~35 Ma.Here the initial India-Asia contact is defined as the time at which the展开更多
Hydrodynamic models are important to many coastal engineering designs and application,especially addressing sediment and water quality.In this study,MIKE 21 two-dimensional(2D)hydrodynamic model based on the flexible ...Hydrodynamic models are important to many coastal engineering designs and application,especially addressing sediment and water quality.In this study,MIKE 21 two-dimensional(2D)hydrodynamic model based on the flexible mesh(FM)technique was used to simulate the surface currents forced by tides and winds in Kanyakumari coast.The model results of the tidal level along shore and cross shore currents are agreed well with measured data in Kanyakumari coast.The major components of tides and currents are analyzed by harmonic analysis methods.Root mean square error(RMSE)values for the measured and model tides(0.017 m and 0.079 m)and currents(0.025 m/s and 0.009 m/s)during the northeast(NE)and southwest(SW)monsoon period are calculated.A series of scenario runs for NE and SW monsoon season are used to understand the regional circulation.The model result shows that the Kanyakumari coast is dominated by tides and surface currents flow,which are influenced by the seasonal reversal wind pattern.Flows around this coastal water have been evidenced small scale cyclonic and anti-cyclonic eddies ranged from∼55 to 120 km in diameter.The cyclonic and anti-cyclonic eddies are mostly appeared in near Kanyakumari and SE coast of Kerala due to local/remotely generated forces.展开更多
文摘Utility of geochemistry in mineral exploration is known since more than half-a-century.In reconnaissance diamond exploration,regolith geochemistry is a well known tool worldwide and helps in distinguishing
文摘The dykes intruding the Hyderabad Granitic Region(HGR)which forms the part of eastern Dharwar Craton extending between northern and northwestern margins of the Cuddapah Basin and western margin of the
基金funding for this project was produced by a Grant-in-Aid for Scientific Research(B) from Japan Society for the Promotion of Science(JSPS) to Tsunogae(Nos.20340148, 22403017)
文摘The objective of this article is to develop a groundwater flow model for a tannery belt using Visual MOD-FLOW Premium 4.4 for analyzing groundwater velocity and its response to various pumping strategies in two stages, viz., steady and transient conditions. The steady state model was calibrated for April 2001, whereas the transient model was employed to forecast groundwater flow under various pumping strategies. The results showed that the total groundwater abstraction was about 80.43% of the groundwater recharge, but 10.25% was used up by evapotranspiration. The groundwater velocity, which is important for contaminant migration, varied from 0.21 to 0.52 m/d in the tannery cluster. The model was more sensitive to recharge from rainfall, hydraulic conductivity and specific yield. Finally, the model showed that the aquifer could sustain a pumping rate of 24892 m3/day without further decline in water level.
基金supported by the Department of Biotechnology under Grant BT/NNT/28/SP18830/2018.
文摘Background:Leber congenital amaurosis(LCA),primarily characterized by retinal degeneration is the most severe form of inherited retinal dystrophy(IRD)responsible for congenital blindness.The presence of phenotypic heterogeneity makes the diagnosis of LCA challenging,especially in the absence of pronounced disease pathognomonic,yet it can be well comprehended by employing molecular diagnosis.Therefore,the present study aimed to reveal the causative mutations in ten LCA patients with variable phenotypes using clinical exome sequencing(CES).Methods:CES was performed in ten unrelated LCA patients.Ophthalmic information and family history of all patients were obtained to make a meaningful interpretation.The clinical exome data was analyzed and prioritized using a bioinformatics pipeline to identify mutations,which was further validated by Sanger sequencing.Segregation analysis was also performed on available family members.Results:CES led to the identification of causative mutations in nine LCA patients.Seven patients harbored a mutation in six LCA candidate genes,including RPE65,LCA5(n=2),CRX,PRPH2,CEP290,and ALMS1,while two patients possess a mutation in IFT80 and RP1,known to cause other diseases.Three novel mutations in LCA5(c.1823del),CRX(c.848del)and CEP290(c.2483G>T)were identified.The current study reports for the first time,a mutation in PRPH2,CEP290,and ALMS1 from the Indian population.Additionally,we observed a novel association of LCA phenotype with IFT80 known to cause Jeune syndrome.Based on the genetic finding,the patient AS09,who harbored a mutation in the RP1 gene,was re-diagnosed with early-onset retinitis pigmentosa.Conclusion:In conclusion,the results underline the importance of CES in clinically diagnosed LCA patients with variable phenotypes.The correlation between mutations in candidate genes and clinical phenotypes,helps to refine the clinical diagnosis.However,molecular evaluation with a larger cohort of LCA patients is needed for better understanding of the mutational spectrum in southern India.
基金supported by the Strategic Project of Science and Technology of Chinese Academy of Sciences (XDB050105003)the State Scholarship Fund of China (41272030)+1 种基金the National Basic Research Program of China (2012CB822001)IGCP608
文摘This is a new report on the early Eocene radiolarian fauna from the Sangdanlin section in the Gyirong region, along the southern margin of the Yarlung Zangbo Suture Zone. The Sangdanlin section measured in this study is divided into three lithostratigraphic units from bottom to top: the Zongzhuo, Sangdanlin, and Zheya formations. Abundant radiolarian fossils were obtained from the Sangdanlin section and 54 species of 30 genera were identified and assigned as follows: Cryptamphorella conara-C. macropora the late Cretaceous Zone and Amphisphaera coronate, Buryella tetradica-Bekoma campechensis, and B.bidartensis-B. divaricata the Paleocene-early Eocene Interval Zones. The Paleocene–early Eocene radiolarian zones are comparable to the radiolarian zones RP4-RP8 in New Zealand. Based on the data of radiolaria and lithofacies, it is suggested that the Zongzhuo Formation should be deposited along the base of the north-facing, continental slope of the Greater Indian continental margin, and the Sangdanlin Formation should be a deep marine, sedimentary sequence located in a foreland basin. The early Eocene radiolarian fauna in the Sangdanlin Formation constrains the initial age of the India-Asia collision to no later than 53.6 Ma.
文摘The complexities in the relationship between winter monsoon rainfall (WMR) over South India and Sea Surface temperature (SST) variability in the southern and tropical Indian Ocean (STIO) are evaluated statistically. The data of the time period of our study (1950-2003) have been divided exactly in two halves to identify predictors. Correlation analysis is done to see the effect of STIO SST variability on winter monsoon rainfall index (WMRI) for South India with a lead-lag of 8 seasons (two years). The significant positive correlation is found between Southern Indian Ocean (SIO) SST and WMRI in July-August-September season having a lag of one season. The SST of the SIO, Bay of Bengal and North Equatorial Indian Ocean are negatively correlated with WMRI at five, six and seven seasons before the onset of winter monsoon. The maximum positive correlation of 0.61 is found from the region south of 500 S having a lag of one season and the negative correlations of 0.60, 0.53 and 0.57 are found with the SST of the regions SIO, Bay of Bengal and North Equatorial Ocean having lags of five, six and seven seasons respectively and these correlation coefficients have confidence level of 99%. Based on the correlation analysis, we defined Antarctic Circumpolar Current Index A and B (ACCIA (A) & ACCIB (B)), Bay of Bengal index (BOBI (C)) and North Equatorial Index (NEI (D)) by averageing SST for the regions having maximum correlation (positive or negative) with WMRI index. These SST indices are used to predict the WMRI using linear and multivariate linear regression models. In addition, we also attempted to detect a dynamic link for the predictability of WMRI using Nino 3.4 index. The predictive skill of these indices is tested by error analysis and Willmott’s index.
文摘The pre-collisional southern margin of Asia can be restored using paleomagnetic data from late Cretaceous rocks from the Lhasa terrane.However,the available data are based either on the red beds or on the intercalated thin layers of lava flows,both of which had been involved in strongly folding.Recent studies show clear evidence for the possibility of serious overprint hence the data could not be reliably used for tectonic interpretation.We report paleomagnetic data from diorite dykes and the grano-diorite country rock in the Gandise belt near the city of Lhasa.U–Pb isotopic dating indicates the intrusive rocks have an age of^82–86 Ma.Fifteen sites yield acceptable Ch RM directions which pass a reversal test.SEM and light microscope observations show primaryintergrowth relationship between magnetite and other minerals within the thin sections.AMS measurement defines a primary magma flow fabric for the intruded dykes and the country rocks.All the characteristics support that the Ch RMs are primary.The paleomagnetic pole calculated from the remanence of the dykes and the country rocks yields a paleolatitude of^14°N which provide a reliable constraint for the southern margin of Asia near Lhasa.Furthermore,the recorded declination shows significant counterclockwise rotation of^20°for the sampling location relative to the north.In consideration of the strike and tectonic setting of the dykes,the strike of the southern margin of Asia is restored which is compatible with the hypothesis of a quasi-linear margin of Eurasia prior to its collision with India.
基金the Department of Space,Government of India,for supporting this work through a research project to RS("Paleoclimate of the past few centuries from Lake-and Tank-bed sediments of Southern India"ISRO-GBP/WG-1 letter No.9/5/2/2004-11)under the Geosphere-Biosphere ProgramAKW and KSthank the Department of Space,the Council of Scientific and Industrial Research and the University Grants Commission,Government of India for junior and Senior Research Fellowships
文摘The Indian summer monsoon exhibits considerable spatio-temporal variability.It is therefore important to understand its dynamics and the inherent periodicities.In this study,we have performed spectral and wavelet analyses of magnetic susceptibility data for sediments from Thimmannanayakanakere(TK)-a small lake in southern India.The main objective of this investigation is to identify and explain the possible origin of the prominent periodicities present in the magnetic susceptibility data.Significant periodicities in the TK χ_(lf)data are centered at 906,232,147,128,96,61,54 and 44 years,which might have a solar origin.The wavelet power spectrum of the raw and detrended χ_(lf)data confirms the findings of spectral analysis and also provides temporal variations of the significant cyclicities during the past3700 cal.years B.P.Positive correlation is documented between sunspot activity and TK xif data;crossspectral analysis of the reconstructed sunspot data and TK xif data suggest that there is a strong coherence between the two datasets as significant periodicities are documented in both.There is a good match between the TK xif and the reconstructed total solar irradiance data for the past 1200 years.However,an out-of-phase relationship is documented at certain time-intervals,which may be attributed to uncertainties in the age-depth model.The results obtained from this study show that solar variations are the main controlling factor of the southwest monsoon and,like other archives from different regions in India,the TK lake sediments have also recorded these solar signatures.
文摘Melioidosis,a disease of public health importance in Southeast Asia and Northern Australia,of late has shown an increasing trend in India,particularly Southern India.We describe a ease of a 39-year-old diabetic patient with left elbow septic arthritis,multiple liver,splenic abscesses, pneumonia,pleural effusion,followed by sepsis syndrome.Blood cultures and culture of the joint aspirate yielded pure growth of Burkholderia psettdomallei(B.pesudomallei),sensitive to carbapenem,co-trimoxazole and resistant to ceftazidime.The patient was successfully treated with imipenem- cilastin.He was discharged on co-trimoxazole to complete the 24 weeks course and follow-up has continued to date.The patient continues to remain asymptomatic.The case re-emphasizes the need to monitor the trend of B.pseudomallei in India,particularly the development of ceftazidime resistance,which incidentally is the drug of choice.
基金supported by the National Natural Science Foundation of China (NSFC) (Grant Nos. 41276002 and 41130859)the National Basic Research Program of China (Grant Nos. 2012CB955603 and 2013CB956201)+1 种基金the NSFC–Shandong Joint Fund for Marine Science Research Centers (Grant No. U1406401)the Fund for Open Research Programs of the Key Laboratory of Meteorological Disaster (Nanjing University of Information Science and Technology), Ministry of Education (KLME1301)
文摘An extreme rainstorm hit southern China during 13–17 December 2013, with a record-breaking daily rainfall rate, large spatial extent, and unusually long persistence. We examined what induced this heavy rainfall process, based on observed rainfall data and NCEP–NCAR reanalysis data through composite and diagnostic methods. The results showed that a Rossby waveguide within the subtropical westerly jet caused the event. The Rossby wave originated from strong cold air intrusion into the subtropical westerly jet over the eastern Mediterranean. With the enhancement and northward shift of the Middle East westerly jet, the Rossby wave propagated slowly eastward and deepened the India–Burma trough, which transported a large amount of moisture from the Bay of Bengal and South China Sea to southern China. Strong divergence in the upper troposphere, caused by the enhancement of the East Asian westerly jet, also favored the heavy rainfall process over Southeast China. In addition, the Rossby wave was associated with a negative-to-positive phase shift and enhancement of the North Atlantic Oscillation, but convergence in the eastern Mediterranean played the key role in the eastward propagation of the Rossby wave within the subtropical westerly jet.
文摘This is an extended abstract of Hu et al.,2012. The timing of the initial collision between India and Asia remains a matter of considerable debate,with views ranging from~70 Ma to~35 Ma.Here the initial India-Asia contact is defined as the time at which the
文摘Hydrodynamic models are important to many coastal engineering designs and application,especially addressing sediment and water quality.In this study,MIKE 21 two-dimensional(2D)hydrodynamic model based on the flexible mesh(FM)technique was used to simulate the surface currents forced by tides and winds in Kanyakumari coast.The model results of the tidal level along shore and cross shore currents are agreed well with measured data in Kanyakumari coast.The major components of tides and currents are analyzed by harmonic analysis methods.Root mean square error(RMSE)values for the measured and model tides(0.017 m and 0.079 m)and currents(0.025 m/s and 0.009 m/s)during the northeast(NE)and southwest(SW)monsoon period are calculated.A series of scenario runs for NE and SW monsoon season are used to understand the regional circulation.The model result shows that the Kanyakumari coast is dominated by tides and surface currents flow,which are influenced by the seasonal reversal wind pattern.Flows around this coastal water have been evidenced small scale cyclonic and anti-cyclonic eddies ranged from∼55 to 120 km in diameter.The cyclonic and anti-cyclonic eddies are mostly appeared in near Kanyakumari and SE coast of Kerala due to local/remotely generated forces.