A Comparative Study on Two Techniques of Reducing the Dimension of Text Feature Space

With the development of large scale text processing, the dimension of text feature space has become larger and larger, which has added a lot of difficulties to natural language processing. How to reduce the dimension has become a practical problem in the field. Here we present two clustering methods, i.e. concept association and concept abstract, to achieve the goal. The first refers to the keyword clustering based on the co occurrence of

Human Adipose Stem Cells Exposed to Gamma Radiation and Inactivity (Stasis) Show Increased Cancer Markers and DNA Damage. A Preliminary Assessment of a Pharmaceutical Formulation to Reverse These Effects and Its Applications for Medical Radiotherapy and the Space Industry

Gamma radiation exposure and physical inactivity occur in medical radiotherapy patients and astronauts resulting in substantial deterioration of their health. At the molecular level, the radiation triggers elevated markers for DNA double-strand breaks and tumorigenicity. Cell stasis is a potential phenomenon associated with low physical activity in recovering cancer patients and astronauts. This preliminary study assessed parameters of stasis and gamma radiation on human adipose stem cells (ADSCs) that have important regenerative functions for the body. A prototype pharmaceutical formulation (PF) was tested to prevent and reverse the effects of radiation and stasis. ADSCs were subjected to short-term (1 - 5 days) and longer-term (8 - 25 days) stasis and radiation with a combined total exposure of alpha, beta and gamma radiation measured at 455 microSv/hr on the Geiger counter. Cell health markers were grouped for characteristics of cellular health (annexin, H2A.X, NO, ROS) and tumorigenicity potential (P13, Ki67, MAPK) that were measured with flow cytometry. Results showed PF to improve cell health in days 1 - 5 compared to stasis (p = 0.01) and radiation (p = 0.02), and PF reduced tumorigenicity compared with stasis (p = 0.018) and radiation (p = 0.03). For longer exposure (8 - 25 days) PF improved cellular health compared with stasis (p = 0.038) and showed a non-significant trend for decreasing radiation effects (p = 0.07). There was decreased tumorigenicity compared with stasis (p = 0.003) and radiation (p = 0.005). This preliminary evaluation of the PF showed it to have 88% (66/75) positive assay results (p < 0.00001 Chi-square) indicating three promising beneficial effects: 1) prevent cell/DNA damage, 2) reduce cancer risk, and 3) recover damaged and precancerous stem cells. The PF could have important applications for medical radiotherapy patients, astronauts and future space mining personnel. PF reduced carcinogenesis and DNA damage of stem cells by approximately 50% from radiation that was the microSievert equivalent of 4 months on board the International Space Station.

A Literary Geographical Analysis of Odour of Chrysanthemums

D.H.Lawrence is one of the most prominent writers in the history of English literature,his works have received widespread attention and criticism.Living in the era of the Industrial Revolution,D.H.Lawrence has a deep understanding of the process of industrialization.This study interprets his work Odour of Chrysanthemums from the perspective of literary geography.The colliery,the miner’s house,and the tavern,the three most representative geographical spaces,are selected to explore the literary geographic genes,geographic memories,and geographic roots in this novel.Through analyzing the methods of geographic elements in setting themes,shaping characters,and promoting the plotsin the novel,this paper explores the theme of industrial civilization’s damage and distortion to individuals,families,and communities.