Jetting-based bioprinting:process,dispense physics,and applications

Jetting-based bioprinting facilitates contactless drop-on-demand deposition of subnanoliter droplets at well-defined positions to control the spatial arrangement of cells,growth factors,drugs,and biomaterials in a highly automated layer-by-layer fabrication approach.Due to its immense versatility,jetting-based bioprinting has been used for various applications,including tissue engineering and regenerative medicine,wound healing,and drug development.A lack of in-depth understanding exists in the processes that occur during jetting-based bioprinting.This review paper will comprehensively discuss the physical considerations for bioinks and printing conditions used in jetting-based bioprinting.We first present an overview of different jetting-based bioprinting techniques such as inkjet bioprinting,laser-induced forward transfer bioprinting,electrohydrodynamic jet bioprinting,acoustic bioprinting and microvalve bioprinting.Next,we provide an in-depth discussion of various considerations for bioink formulation relating to cell deposition,print chamber design,droplet formation and droplet impact.Finally,we highlight recent accomplishments in jetting-based bioprinting.We present the advantages and challenges of each method,discuss considerations relating to cell viability and protein stability,and conclude by providing insights into future directions of jetting-based bioprinting.

Tensile Shock Physics in Compressible Thermoviscoelastic Solid Medium

This paper addresses tensile shock physics in thermoviscoelastic (TVE) solids without memory. The mathematical model is derived using conservation and balance laws (CBL) of classical continuum mechanics (CCM), incorporating the contravariant second Piola-Kirchhoff stress tensor, the covariant Green’s strain tensor, and its rates up to order n. This mathematical model permits the study of finite deformation and finite strain compressible deformation physics with an ordered rate dissipation mechanism. Constitutive theories are derived using conjugate pairs in entropy inequality and the representation theorem. The resulting mathematical model is both thermodynamically and mathematically consistent and has closure. The solution of the initial value problems (IVPs) describing evolutions is obtained using a variationally consistent space-time coupled finite element method, derived using space-time residual functional in which the local approximations are in hpk higher-order scalar product spaces. This permits accurate description problem physics over the discretization and also permits precise a posteriori computation of the space-time residual functional, an accurate measure of the accuracy of the computed solution. Model problem studies are presented to demonstrate tensile shock formation, propagation, reflection, and interaction. A unique feature of this research is that tensile shocks can only exist in solid matter, as their existence requires a medium to be elastic (presence of strain), which is only possible in a solid medium. In tensile shock physics, a decrease in the density of the medium caused by tensile waves leads to shock formation ahead of the wave. In contrast, in compressive shocks, an increase in density and the corresponding compressive waves result in the formation of compression shocks behind of the wave. Although these are two similar phenomena, they are inherently different in nature. To our knowledge, this work has not been reported in the published literature.

ESTIMATION OF AVERAGE DIFFERENTIAL ENTROPY FOR A STATIONARY ERGODIC SPACE-TIME RANDOM FIELD ON A BOUNDED AREA

In this paper,we mainly discuss a discrete estimation of the average differential entropy for a continuous time-stationary ergodic space-time random field.By estimating the probability value of a time-stationary random field in a small range,we give an entropy estimation and obtain the average entropy estimation formula in a certain bounded space region.It can be proven that the estimation of the average differential entropy converges to the theoretical value with a probability of 1.In addition,we also conducted numerical experiments for different parameters to verify the convergence result obtained in the theoretical proofs.

A novel encoding mechanism for particle physics

This study proposes a novel particle encoding mechanism that seamlessly incorporates the quantum properties of particles,with a specific emphasis on constituent quarks.The primary objective of this mechanism is to facilitate the digital registration and identification of a wide range of particle information.Its design ensures easy integration with different event generators and digital simulations commonly used in high-energy experiments.Moreover,this innovative framework can be easily expanded to encode complex multi-quark states comprising up to nine valence quarks and accommodating an angular momentum of up to 99/2.This versatility and scalability make it a valuable tool.

Robust Space-Time Adaptive Track-Before-Detect Algorithm Based on Persymmetry and Symmetric Spectrum

Underwater monopulse space-time adaptive track-before-detect method,which combines space-time adaptive detector(STAD)and the track-before-detect algorithm based on dynamic programming(DP-TBD),denoted as STAD-DP-TBD,can effectively detect low-speed weak targets.However,due to the complexity and variability of the underwater environment,it is difficult to obtain sufficient secondary data,resulting in a serious decline in the detection and tracking performance,and leading to poor robustness of the algorithm.In this paper,based on the adaptive matched filter(AMF)test and the RAO test,underwater monopulse AMF-DP-TBD algorithm and RAO-DP-TBD algorithm which incorporate persymmetry and symmetric spectrum,denoted as PSAMF-DP-TBD and PS-RAO-DP-TBD,are proposed and compared with the AMF-DP-TBD algorithm and RAO-DP-TBD algorithm based on persymmetry array,denoted as P-AMF-DP-TBD and P-RAO-DP-TBD.The simulation results show that the four methods can work normally with sufficient secondary data and slightly insufficient secondary data,but when the secondary data is severely insufficient,the P-AMF-DP-TBD and P-RAO-DP-TBD algorithms has failed while the PSAMF-DP-TBD and PS-RAO-DP-TBD algorithms still have good detection and tracking capabilities.

Exploring device physics of perovskite solar cell via machine learning with limited samples

Perovskite solar cells(PsCs)have developed tremendously over the past decade.However,the key factors influencing the power conversion efficiency(PCE)of PSCs remain incompletely understood,due to the complexity and coupling of these structural and compositional parameters.In this research,we demon-strate an effective approach to optimize PSCs performance via machine learning(ML).To address chal-lenges posed by limited samples,we propose a feature mask(FM)method,which augments training samples through feature transformation rather than synthetic data.Using this approach,squeeze-and-excitation residual network(SEResNet)model achieves an accuracy with a root-mean-square-error(RMSE)of 0.833%and a Pearson's correlation coefficient(r)of 0.980.Furthermore,we employ the permu-tation importance(PI)algorithm to investigate key features for PCE.Subsequently,we predict PCE through high-throughput screenings,in which we study the relationship between PCE and chemical com-positions.After that,we conduct experiments to validate the consistency between predicted results by ML and experimental results.In this work,ML demonstrates the capability to predict device performance,extract key parameters from complex systems,and accelerate the transition from laboratory findings to commercialapplications.

Ultrafast photoemission electron microscopy:A multidimensional probe of nonequilibrium physics

Exploring the realms of physics that extend beyond thermal equilibrium has emerged as a crucial branch of condensed matter physics research.It aims to unravel the intricate processes involving the excitations,interactions,and annihilations of quasi-and many-body particles,and ultimately to achieve the manipulation and engineering of exotic non-equilibrium quantum phases on the ultrasmall and ultrafast spatiotemporal scales.Given the inherent complexities arising from many-body dynamics,it therefore seeks a technique that has efficient and diverse detection degrees of freedom to study the underlying physics.By combining high-power femtosecond lasers with real-or momentum-space photoemission electron microscopy(PEEM),imaging excited state phenomena from multiple perspectives,including time,real space,energy,momentum,and spin,can be conveniently achieved,making it a unique technique in studying physics out of equilibrium.In this context,we overview the working principle and technical advances of the PEEM apparatus and the related laser systems,and survey key excited-state phenomena probed through this surface-sensitive methodology,including the ultrafast dynamics of electrons,excitons,plasmons,spins,etc.,in materials ranging from bulk and nano-structured metals and semiconductors to low-dimensional quantum materials.Through this review,one can further envision that time-resolved PEEM will open new avenues for investigating a variety of classical and quantum phenomena in a multidimensional parameter space,offering unprecedented and comprehensive insights into important questions in the field of condensed matter physics.

Physics-based seismic analysis of ancient wood structure:fault-to-structure simulation

Based on the domain reduction method,this study employs an SEM-FEM hybrid workflow which integrates the advantages of the spectral element method(SEM)for flexible and highly efficient simulation of seismic wave propagation in a three-dimensional(3D)regional-scale geophysics model and the finite element method(FEM)for fine simulation of structural response including soil-structure interaction,and performs a physics-based simulation from initial fault rupture on an ancient wood structure.After verification of the hybrid workflow,a large-scale model of an ancient wood structure in the Beijing area,The Tower of Buddhist Incense,is established and its responses under the 1665 Tongxian earthquake and the 1730 Yiheyuan earthquake are simulated.The results from the simulated ground motion and seismic response of the wood structure under the two earthquakes demonstrate that this hybrid workflow can be employed to efficiently provide insight into the relationships between geophysical parameters and the structural response,and is of great significance toward accurate input for seismic simulation of structures under specific site and fault conditions.

Curved Space-Time at the Planck Scale

This paper presents a physically plausible and somewhat illuminating first step in extending the fundamental principles of mechanical stress and strain to space-time. Here the geometry of space-time, encoded in the metric tensor, is considered to be made up of a dynamic lattice of extremely small, localized fields that form a perfectly elastic Lorentz symmetric space-time at the global (macroscopic) scale. This theoretical model of space-time at the Planck scale leads to a somewhat surprising result in which matter waves in curved space-time radiate thermal gravitational energy, as well as an equally intriguing relationship for the anomalous dispersion of light in a gravitational field.

Virtually coupled train set control subject to space-time separation:A distributed economic MPC approach with emergency braking configuration

The emerging virtual coupling technology aims to operate multiple train units in a Virtually Coupled Train Set(VCTS)at a minimal but safe distance.To guarantee collision avoidance,the safety distance should be calculated using the state-of-the-art space-time separation principle that separates the Emergency Braking(EB)trajectories of two successive units during the whole EB process.In this case,the minimal safety distance is usually numerically calculated without an analytic formulation.Thus,the constrained VCTS control problem is hard to address with space-time separation,which is still a gap in the existing literature.To solve this problem,we propose a Distributed Economic Model Predictive Control(DEMPC)approach with computation efficiency and theoretical guarantee.Specifically,to alleviate the computation burden,we transform implicit safety constraints into explicitly linear ones,such that the optimal control problem in DEMPC is a quadratic programming problem that can be solved efficiently.For theoretical analysis,sufficient conditions are derived to guarantee the recursive feasibility and stability of DEMPC,employing compatibility constraints,tube techniques and terminal ingredient tuning.Moreover,we extend our approach with globally optimal and distributed online EB configuration methods to shorten the minimal distance among VCTS.Finally,experimental results demonstrate the performance and advantages of the proposed approaches.

基于Interactive Physics的物理习题教学--以2023年高考全国乙卷25题和湖北卷15题为例

在传统高中物理教学中,多过程碰撞的物理过程很难在板书上展现出来,成为教学的一大难点。基于Interactive Physics仿真功能,以2023年高考全国乙卷25题和湖北卷15题为例,将多过程碰撞的物理过程可视化,直观展现物理模型,帮助学生理解题目的复杂情境,有效缩短学习时间,提高教学质量和教学效率,实现最优化的教学目标。

Design and Research of an Intelligent Learning System for University Physics

In order to break through the limitations of traditional teaching,realize the integration of online and offline teaching,and optimize the intelligent learning experience of university physics,this paper proposes the design of an intelligent learning system for university physics based on cloud computing platforms,and applies this system to teaching environment of university physics.It successfully integrates emerging technologies such as cloud computing,machine learning,and situational awareness,integrates learning context awareness,intelligent recording and broadcasting,resource sharing,learning performance prediction,and content planning and recommendation,and comprehensively improves the quality of university physics teaching.It can optimize the teaching process and deepen intelligent teaching reform,aiming at providing references for the teaching practice of university physics.

Reform and Practice of University Physics Experimental Teaching Based on OBE Concept

Aiming at the problems of unclear teaching objectives,obsolete content,and single method in the experimental teaching of university physics at our university,we have implemented a series of reform initiatives.It mainly includes clarifying the student-centered teaching objectives,optimizing the experimental content,innovating the teaching methods,improving the assessment and evaluation system,and improving the experimental conditions[1,2].After the implementation of the reform,the learning effectiveness of students has been significantly improved,the teaching level of teachers has been significantly enhanced,the curriculum system has been optimized,the efficiency of teaching management has been enhanced,and social recognition has been strengthened.Practice shows that the teaching reform based on the outcome-based education concept effectively improves the quality of university physics experimental teaching and lays the foundation for cultivating innovative talents.

Integration of Ideological and Political Education in College Physics Courses Under the Reform of Smart Teaching

The development of the times has prompted China to enhance the quality of education and the value of talent.As guides for students,teachers should conscientiously implement ideological and political education,create college physics courses that are more in line with modern talent cultivation,eliminate the fixed and singular nature of traditional teaching,and find the integration points of ideological and political education.Teachers need to use the textbook itself,the expansion of resources in smart classrooms,and current technological progress to implement ideological and political education in order to cultivate more high-quality and high-level comprehensive talents for society.

Physics of Clocks in Absolute Space-Time

20th century physics experimentally established beyond doubt the fact that moving clocks read differently from “static” clocks. This fact is typically interpreted as support for special relativity. On the other hand, the same century produced proof that clocks at various locations in the gravitational field also read differently, and this fact is explained by general relativity, which is, in general, not Lorentz transformable. This paper establishes a common framework for the physics of clocks in these different situations.

Physics in Discrete Spaces: On Space-Time Organization

We see the whole universe as a collection of very simple binary physical systems. With this assumption, we put forward a detailed model of discrete spaces. Our own universe with its four dimensions, shared between one time-like dimension and three space-like dimensions, as well as the Minkowski metrics, are emerging properties of the model.

COMSOL Multiphysics在物理化学教学中的应用

将计算仿真融入大学化学专业课程的讲授是帮助学生具体化抽象概念、提升教学质量的新思路。本文介绍了多场物理仿真软件COMSOL Multiphysics的基本原理和操作,并结合大学物理化学课程的教学内容,总结说明了该软件在相平衡、化学平衡以及化学动力学等章节中的应用实例。由学生反馈可知,计算模拟软件在课堂教学中的可视化的演示,增强了学生对所学知识的理解和掌握,提高了学生的学习热情和思考深度。

The Longmen Cloud Physics Field Experiment Base, China Meteorological Administration

Aiming at the needs of mechanism analysis of rainstorms and development of numerical prediction models in south China, the Guangzhou Institute of Tropical and Marine Meteorology of China Meteorological Administration and the Chinese Academy of Meteorological Sciences jointly set up the Longmen Cloud Physics Field Experiment Base,China Meteorological Administration. This paper introduces the instruments and field experiments of this base, provides an overview of the recent advances in retrieval algorithms of microphysical parameters, improved understanding of microphysical characteristics, as well as the formation mechanisms and numerical prediction of heavy rainfalls in south China based on the field experiments dataset.

基于Vernier Video Physics软件的物理实验探究——以“探究平抛运动的特点”为例

智能手机的飞速发展和智能手机APP的不断更新对当今社会的各个方面都产生了深远的影响。与此同时,智能手机APP也逐渐被引入课堂教学中,为学生提供了自主学习的机会,也使物理实验教学模式发生了巨大的改变,成了广大教育者关注的热点。利用Vernier Video Physics软件和Vernier Graphical Analysis软件,再结合平抛运动实验仪,对小钢球的运动轨迹进行逐帧追踪定位,得到小钢球做平抛运动的y-x图像、x-t图像、y-t图像和v_(y)-t图像,再对图像进行相应函数拟合,经过数据分析,得到小钢球做平抛运动在水平方向和竖直方向的运动特点。利用智能手机APP辅助高中物理实验教学可以激发学生的学习兴趣,帮助学生理解物理概念和规律,使学生积极主动地参与到实验中来,培养他们的动手能力,提升他们的实验素养。

Rock physics and seismic reflectivity parameterization and amplitude variation with offsets inversion in terms of total organic carbon indicator

Total organic carbon (TOC) prediction with elastic parameter inversions has been widely used in the identification and evaluation of source rocks. However, the elastic parameters used to predict TOC are not only determined by TOC but also depend on the other physical properties of source rocks. Besides, the TOC prediction with the elastic parameters inversion is an indirect method based on the statistical relationship obtained from well logs and experiment data. Therefore, we propose a rock physics model and define a TOC indicator mainly affected by TOC to predict TOC directly. The proposed rock physics model makes the equivalent elastic moduli of source rocks parameterized by the TOC indicator. Combining the equivalent elastic moduli of source rocks and Gray’s approximation leads to a novel linearized approximation of the P-wave reflection coefficient incorporating the TOC indicator. Model examples illustrate that the novel reflectivity approximation well agrees with the exact Zoeppritz equation until incident angles reach 40°. Convoluting the novel P-wave reflection approximation with seismic wavelets as the forward solver, an AVO inversion method based on the Bayesian theory is proposed to invert the TOC indicator with seismic data. The synthetic examples and field tests validate the feasibility and stability of the proposed AVO inversion approach. Using the inversion results of the TOC indicator, TOC is directly and accurately estimated in the target area.