Molecular mechanics calculations, based on equations such as the one below, are used to investigate a colorectal cancer drug, 5-fluorouracil, intercalated into a clay, montmorillonite. This combination is currently be...Molecular mechanics calculations, based on equations such as the one below, are used to investigate a colorectal cancer drug, 5-fluorouracil, intercalated into a clay, montmorillonite. This combination is currently being considered as a drug delivery system. The swelling of clays has been studied since the 1930s and is still not fully understood. Spartan ’14 is used for the calculations. Semi-empirical and ab initio basis set scaling is also examined since there are roughly 300 atoms involved in the full model.展开更多
The purpose of this study was to gain knowledge about the demographics, injury and training habits of those competing in obstacle race events. Participants included 122 athletes (males, n = 75; females, n = 47) (30...The purpose of this study was to gain knowledge about the demographics, injury and training habits of those competing in obstacle race events. Participants included 122 athletes (males, n = 75; females, n = 47) (30.8 ± 9.3 yrs., 172.5 ± 17.5 cm, 76.4± 13.9 lbs.) who completed a voluntary online survey (Qualtrics ). Eighty-two percent reported competing in high school athletics, while only 25% reported competing at the collegiate level. Eighty-three percent of participants reported completing some sort of training prior to the race. Forty-one percent of participants reported training for less than 3 months while 32% trained for 3-6 months prior to the event. Training consisted of 15.5 ± 13.1 miles of running, 4.6 a: 7.2 miles of trail running and 11.7 ± 35.5 miles of biking. Twenty-five percent of the participants reported suffering an injury during a race and 3% reported being injured on more than one occasion. The most common injuries were overuse injuries (11%), muscle strains (9%) and sprains (8%) particularly to the knee and ankle. The injury rate appears to be high as 25% of the participants reported suffering an injury during a race. A longer training period with a focus on strengthening the stabilizing muscles of the lower extremities may help lower the incidence of injury.展开更多
文摘Molecular mechanics calculations, based on equations such as the one below, are used to investigate a colorectal cancer drug, 5-fluorouracil, intercalated into a clay, montmorillonite. This combination is currently being considered as a drug delivery system. The swelling of clays has been studied since the 1930s and is still not fully understood. Spartan ’14 is used for the calculations. Semi-empirical and ab initio basis set scaling is also examined since there are roughly 300 atoms involved in the full model.
文摘The purpose of this study was to gain knowledge about the demographics, injury and training habits of those competing in obstacle race events. Participants included 122 athletes (males, n = 75; females, n = 47) (30.8 ± 9.3 yrs., 172.5 ± 17.5 cm, 76.4± 13.9 lbs.) who completed a voluntary online survey (Qualtrics ). Eighty-two percent reported competing in high school athletics, while only 25% reported competing at the collegiate level. Eighty-three percent of participants reported completing some sort of training prior to the race. Forty-one percent of participants reported training for less than 3 months while 32% trained for 3-6 months prior to the event. Training consisted of 15.5 ± 13.1 miles of running, 4.6 a: 7.2 miles of trail running and 11.7 ± 35.5 miles of biking. Twenty-five percent of the participants reported suffering an injury during a race and 3% reported being injured on more than one occasion. The most common injuries were overuse injuries (11%), muscle strains (9%) and sprains (8%) particularly to the knee and ankle. The injury rate appears to be high as 25% of the participants reported suffering an injury during a race. A longer training period with a focus on strengthening the stabilizing muscles of the lower extremities may help lower the incidence of injury.