This Paper has first studied the simplified model of tubular heat exchanger which is widely used in the industry and other field.On the basis of reference 2,a new pole assignment design method of pro-cess control syst...This Paper has first studied the simplified model of tubular heat exchanger which is widely used in the industry and other field.On the basis of reference 2,a new pole assignment design method of pro-cess control system with derivative control action is found.For the above system,the method and the for-mation which calculate the feedback matrix K and gain matrix L is given,and the simulation of the system is made.展开更多
When designing a complex mechatronics system, such as high speed trains, it is relatively difficult to effectively simulate the entire system's dynamic behaviors because it involves multi-disciplinary subsystems. Cur...When designing a complex mechatronics system, such as high speed trains, it is relatively difficult to effectively simulate the entire system's dynamic behaviors because it involves multi-disciplinary subsystems. Currently, a most practical approach for multi-disciplinary simulation is interface based coupling simulation method, but it faces a twofold challenge: spatial and time unsynchronizations among multi-directional coupling simulation of subsystems. A new collaborative simulation method with spatiotemporal synchronization process control is proposed for coupling simulating a given complex mechatronics system across multiple subsystems on different platforms. The method consists of 1) a coupler-based coupling mechanisms to define the interfacing and interaction mechanisms among subsystems, and 2) a simulation process control algorithm to realize the coupling simulation in a spatiotemporal synchronized manner. The test results from a case study show that the proposed method 1) can certainly be used to simulate the sub-systems interactions under different simulation conditions in an engineering system, and 2) effectively supports multi-directional coupling simulation among multi-disciplinary subsystems. This method has been successfully applied in China high speed train design and development processes, demonstrating that it can be applied in a wide range of engineering systems design and simulation with improved efficiency and effectiveness.展开更多
This work provides an overview of distillation processes,including process design for different distillation processes,selection of entrainers for special distillation processes,system integration and intensification ...This work provides an overview of distillation processes,including process design for different distillation processes,selection of entrainers for special distillation processes,system integration and intensification of distillation processes,optimization of process parameters for distillation processes and recent research progress in dynamic control strategies.Firstly,the feasibility of using thermodynamic topological theories such as residual curve,phase equilibrium line and distillation boundary line to analyze different separation regions is discussed,and the rationality of distillation process design is discussed by using its feasibility.Secondly,the application of molecular simulation methods such as molecular dynamics simulation and quantum chemical calculation in the screening of entrainer is discussed for the extractive distillation process.The thermal coupling mechanism of different distillation processes is used to explore the process of different process intensifications.Next,a mixed integer nonlinear optimization strategy for the distillation process based on different algorithms is introduced.Finally,the improvement of dynamic control strategies for different distillation processes in recent years is summarized.This work focuses on the application of process intensification and system optimization in the design of distillation process,and analyzes the challenges,prospects,and development trends of distillation technology in the separation of multicomponent azeotropes.展开更多
The p-xylene(PX) oxidation process is of great industrial importance because of the strong demand of the global polyester fiber.A steady-state model of the PX oxidation has been studied by many researchers.In our prev...The p-xylene(PX) oxidation process is of great industrial importance because of the strong demand of the global polyester fiber.A steady-state model of the PX oxidation has been studied by many researchers.In our previous work,a novel industrial p-xylene oxidation reactor model using the free radical mechanism based kinetics has been developed.However,the disturbances such as production rate change,feed composition variability and reactor temperature changes widely exist in the industry process.In this paper,dynamic simulation of the PX oxidation reactor was designed by Aspen Dynamics and used to develop an effective plantwide control structure,which was capable of effectively handling the disturbances in the load and the temperature of the reactor.Step responses of the control structure to the disturbances were shown and served as the foundation of the smooth operation and advanced control strategy of this process in our future work.展开更多
This paper attempts to set a unified scene for various linear time-invariant (LTI) control system design schemes, by transforming the existing concept of “computer-aided control system design” (CACSD) to novel “com...This paper attempts to set a unified scene for various linear time-invariant (LTI) control system design schemes, by transforming the existing concept of “computer-aided control system design” (CACSD) to novel “computer-automated control system design” (CAutoCSD). The first step towards this goal is to accommodate, under practical constraints, various design objectives that are desirable in both time and frequency domains. Such performance-prioritised unification is aimed at relieving practising engineers from having to select a particular control scheme and from sacrificing certain performance goals resulting from pre-commitment to such schemes. With recent progress in evolutionary computing based extra-numeric, multi-criterion search and optimisation techniques, such unification of LTI control schemes becomes feasible, analytical and practical, and the resultant designs can be creative. The techniques developed are applied to, and illustrated by, three design problems. The unified approach automatically provides an integrator for zero-steady state error in velocity control of a DC motor, and meets multiple objectives in the design of an LTI controller for a non-minimum phase plant and offers a high-performance LTI controller network for a non-linear chemical process.展开更多
In this paper, the dynamics of coherent laser control of potassium atoms is studied by using the time-dependent multilevel approach (TDMA). The calculation results of population transfer are presented with different...In this paper, the dynamics of coherent laser control of potassium atoms is studied by using the time-dependent multilevel approach (TDMA). The calculation results of population transfer are presented with different laser fields. The results show that the population can be transferred to target state completely by a specially designed laser field.展开更多
Objective: This paper takes the example of a Panax notoginseng extraction workshop and designs an automated production workshop with advanced domestic capabilities. Methods: 1) Based on the small-scale Panax notoginse...Objective: This paper takes the example of a Panax notoginseng extraction workshop and designs an automated production workshop with advanced domestic capabilities. Methods: 1) Based on the small-scale Panax notoginseng extraction process, the feasibility of the workshop production process is demonstrated. 2) The workshop process design for Panax Notoginseng saponin extraction is completed, including production organization plans and the selection of key equipment. 3) For the Panax notoginseng extraction workshop process, an automated production control system is designed. Conclusion: Through optimized design of the production process and automation system, continuous and automated production of traditional Chinese medicine extraction is achieved, leading to improvements in drug quality and production efficiency.展开更多
The method of designing industrial processes of quench cooling, in particular, the speed of the conveyor movement with regard to shape and sizes of parts to be quenched, thermal and physical properties of material and...The method of designing industrial processes of quench cooling, in particular, the speed of the conveyor movement with regard to shape and sizes of parts to be quenched, thermal and physical properties of material and cooling capacity of quenchants has been developed. The suggested designing method and databases are the basis for the complete automation of industrial processes of quench cooling, especially for continuous conveyor lines, with the purpose of making high-strength materials. The process is controlled by infrared technique.展开更多
From a regulatory perspective,drug quality consistency evaluation must concern different processes used for the same drug.In this study,an assessment strategy based on quality by design(QbD)was developed for populatio...From a regulatory perspective,drug quality consistency evaluation must concern different processes used for the same drug.In this study,an assessment strategy based on quality by design(QbD)was developed for population pharmaceutical quality evaluation.A descriptive analysis method based on QbD concept was first established to characterize the process by critical evaluation attributes(CEAs).Then quantitative analysis method based on an improved statistical process control(SPC)method was established to investigate the process indicators(PIs)in the process population,such as mean distribution,batch-to-batch difference and abnormal quality probability.After that rules for risk assessment were established based on the SPC limitations and parameters.Both the SPC parameters of the CEAs and the risk of PIs were visualized according to the interaction test results to obtain a better understanding of the population pharmaceutical quality.Finally,an assessment strategy was built and applied to generic drug consistency assessment,process risk assessment and quality trend tracking.The strategy demonstrated in this study could help reveal quality consistency from the perspective of process control and process risk,and further show the recent development status of domestic pharmaceutical production processes.In addition,a process risk assessment and population quality trend tracking provide databased information for approval.Not only can this information serve as a further basis for decisionmaking by the regulatory authority regarding early warnings,but it can also reduce some avoidable adverse reactions.With continuous addition of data,dynamic population pharmaceutical quality is meaningful for emergencies and decision-making regarding drug regulation.展开更多
In this paper,effects of conditions in phenol sulfonic acid(PSA) plating for tin coating of MR low carbon aluminum killed steel on trace Pb were examined.Trace Pb was measured by atomic absorption spectrometry(AAS)and...In this paper,effects of conditions in phenol sulfonic acid(PSA) plating for tin coating of MR low carbon aluminum killed steel on trace Pb were examined.Trace Pb was measured by atomic absorption spectrometry(AAS)and glow discharge spectrometry,and coating morphology was observed by scanning electronic microscopy(SEM).Corrosion resistance of the tin coating was analyzed by electrochemical methods.The results indicated that Pb content in the tin coating reduced as bath temperature increased.When the temperature exceeded40 ℃,the grains in the coating were coarse and loose,reducing the corrosion resistance.As current density increased,Pb content increased rapidly,while low current density plating could lead to drain regions.The plating speed had no obvious effect on trace Pb in tin coating.In the tin plating layer,Pb was enriched at the surface and gradually reduced to zero along the depth.At bath temperature of 40 ℃ and current density of 20 A·dm^(-2),the amount of Pb could be less than 100 mg·kg^(-1) with excellent corrosion resistance.展开更多
The focus of this paper is to investigate different control structures(single-loop PI control) for a dividing wall(Petlyuk) column for separating ethanol, n-propanol and n-butanol. Four control structures are studied....The focus of this paper is to investigate different control structures(single-loop PI control) for a dividing wall(Petlyuk) column for separating ethanol, n-propanol and n-butanol. Four control structures are studied. All the results are simulations based on Aspen Plus. Control structure 1(CS1) is stabilizing control structure with only temperature controllers. CS2, CS3 and CS4, containing also composition controllers, are introduced to reduce the steady state composition deviations. CS2 adds a distillate composition controller(CCDB) on top of CS1. CS3 is much more complicated with three temperature-composition cascade controllers and in addition a selector to the reboiler duty to control the maximum controller output of light impurity composition control in side stream and bottom impurity control in the prefractionator. CS4 adds another high selector to control the light impurity in the sidestream. Surprisingly, when considering the dynamic and even steady state performance of the proposed control structures, CS1 proves to be the best control structure to handle feed disturbances inserted into the three-product Petlyuk column.展开更多
Dividing wall column(DWC)is shown to be energy efficient compared to conventional column sequence for multi components separation,which is used for olefin separation in fluidization methanol to propylene process in th...Dividing wall column(DWC)is shown to be energy efficient compared to conventional column sequence for multi components separation,which is used for olefin separation in fluidization methanol to propylene process in the present work.Detailed design for pilot DWC was performed and five control structures,i.e.composition control(CC),temperature control(TC),composition-temperature control(CC-TC),temperature difference control(TDC),double temperature difference control(DTDC)were proposed to circumvent feed disturbance.Sensitivity analysis and singular value decomposition(SVD)were used as criterion to select the controlled temperature locations in TC,CC-TC,TDC and DTDC control loops.The steady simulation result demonstrates that 25.7% and 30.2% duty can be saved for condenser and reboiler by substituting conventional column sequence with DWC,respectively.As for control structure selection,TC and TDC perform better than other three control schemes with smaller maximum deviation and shorter settling time.展开更多
Since Lowry et al. [1992] proposed a multivariate version of theexponentially weighted moving average (EWMA) control chart, the multivariate EWMA control chart hasbecome more and more popular in monitoring production ...Since Lowry et al. [1992] proposed a multivariate version of theexponentially weighted moving average (EWMA) control chart, the multivariate EWMA control chart hasbecome more and more popular in monitoring production processes, especially in chemical processes.A major advantage of multivariate EWMA statistics is that it is sensitive to small and moderateshifts in the mean vector. However, when a multivariate EWMA chart issues a signal, it is difficultto identify which variable or set of variables is out of control. In this paper, we introduce anew approach to diagnosing signals from a multivariate EWMA control chart. The implementationprocedure is that when the multivariate EWMA control chart issues a signal, we adopt a univariatediagnostic procedure to identify the variables or/and the principal components that caused thesignal.展开更多
Extractive distillation is an effective method for separating azeotropic or close boiling point mixtures by adding a third component.Various technologies for performing the extractive distillation process have been ex...Extractive distillation is an effective method for separating azeotropic or close boiling point mixtures by adding a third component.Various technologies for performing the extractive distillation process have been explored to protect the environment and save resources.This paper focuses on the improvement of these advanced technologies in recent years.Extractive distillation is retrieved and analyzed from the view of phase equilibrium,selection of solvent in extractive distillation,process design,energy conservation,and dynamic control.The quantitative structure–property relationship used in extractive distillation is discussed,and the future development of extractive distillation is proposed to determine how the solvent affects the relative volatility of the separated mixture.In the steady state design,the relationship between the curvature of the residue curve and parameters of the optimal steady state is also highlighted as another field worthy of further study to simplify the distillation process.展开更多
Seepage flow through soils,rocks and geotechnical structures has a great influence on their stabilities and performances,and seepage control is a critical technological issue in engineering practices.The physical mech...Seepage flow through soils,rocks and geotechnical structures has a great influence on their stabilities and performances,and seepage control is a critical technological issue in engineering practices.The physical mechanisms associated with various engineering measures for seepage control are investigated from a new perspective within the framework of continuum mechanics;and an equation-based classification of seepage control mechanisms is proposed according to their roles in the mathematical models for seepage flow,including control mechanisms by coupled processes,initial states,boundary conditions and hydraulic properties.The effects of each mechanism on seepage control are illustrated with examples in hydroelectric engineering and radioactive waste disposal,and hence the reasonability of classification is demonstrated.Advice on performance assessment and optimization design of the seepage control systems in geotechnical engineering is provided,and the suggested procedure would serve as a useful guidance for cost-effective control of seepage flow in various engineering practices.展开更多
Crystallization is one of the oldest separation and purification unit operations, and has recently contributed to significant improvements in producing higher-value products with specific properties and in building ef...Crystallization is one of the oldest separation and purification unit operations, and has recently contributed to significant improvements in producing higher-value products with specific properties and in building efficient manufacturing processes. In this paper, we review recent developments in crystal engineering and crystallization process design and control in the pharmaceutical industry. We systematically summarize recent methods for understanding and developing new types of crystals such as co-crystals, polymorphs, and solvates, and include several milestones such as the launch of the first co-crystal drug, Entresto (No- vartis), and the continuous manufacture of Orkambi (Vertex). Conventional batch and continuous processes, which are becoming increasingly mature, are being coupled with various control strategies and the recently developed crystallizers are thus adapting to the needs of the pharmaceutical industry. The development of crystallization process design and control has led to the appearance of several new and innovative crystal- lizer geometries for continuous operation and improved performance. This paper also reviews major recent orogress in the area of process analytical technology.展开更多
Achieving Six-Sigma process capability starts with l istening to the Voice of the Customers, and it becomes a reality by combining th e People Power and the Process Power of the organisation. This paper presents a Six...Achieving Six-Sigma process capability starts with l istening to the Voice of the Customers, and it becomes a reality by combining th e People Power and the Process Power of the organisation. This paper presents a Six-Sigma implementation case study carried out in a magnet manufacturing compa ny, which produces bearing magnets to be used in energy meters. If the thickness of the produced bearing magnets is between 2.35 mm and 2.50 mm, they will be ac cepted by the customers. All the time the company could not produce the bearing magnets within the specified thickness range, as their process distribution was flat with 2.20 mm as lower control limit and 2.60 mm as upper control limit. This resulted in a huge loss in the form of non-conformities, loss of time and goodwill. The process capability of the company then was around 0.40. Organisat ion restructuring was carried out to reap the benefit of the People Power of the organisation. Statistically designed experiments (Taguchi Method based Design o f Experiments), Online quality control tools (Statistical Process Control To ols) were effectively used to complete the DMAIC (Define, Measure, Analyse, Impr ove and Control) cycle to reap the benefit of the Process Power of the organisat ion. Presently the company enjoys a process capability of 1.75, a way towards Si x-Sigma Process Capability.展开更多
In this paper, design and fabrication of a commemorative plaque are described and presented. The plaque was fabricated to honour the memory of the 14 women massacred at L'Ecole Polytechnique in Montreal. This plaque ...In this paper, design and fabrication of a commemorative plaque are described and presented. The plaque was fabricated to honour the memory of the 14 women massacred at L'Ecole Polytechnique in Montreal. This plaque is the result of a project partnership between the Faculties of Engineering and Fine Arts, and was sponsored by the Office of the Vice-President Academic and Provost. An art design was selected through a contest coordinated by the Visual Arts Departmment. The selected art design was then turned over to the Mechanical Engineering Department to be converted to a 3-dimensional (3D) solid model and then eventually fabricated on a computer numerical control (CNC) milling machine. The fabricated plaque was unveiled during the December 2010 Memorial event at UVic.展开更多
文摘This Paper has first studied the simplified model of tubular heat exchanger which is widely used in the industry and other field.On the basis of reference 2,a new pole assignment design method of pro-cess control system with derivative control action is found.For the above system,the method and the for-mation which calculate the feedback matrix K and gain matrix L is given,and the simulation of the system is made.
基金Supported by National High Technology Research and Development Program of China(863 Program,Grant No.2015AA043701-02)
文摘When designing a complex mechatronics system, such as high speed trains, it is relatively difficult to effectively simulate the entire system's dynamic behaviors because it involves multi-disciplinary subsystems. Currently, a most practical approach for multi-disciplinary simulation is interface based coupling simulation method, but it faces a twofold challenge: spatial and time unsynchronizations among multi-directional coupling simulation of subsystems. A new collaborative simulation method with spatiotemporal synchronization process control is proposed for coupling simulating a given complex mechatronics system across multiple subsystems on different platforms. The method consists of 1) a coupler-based coupling mechanisms to define the interfacing and interaction mechanisms among subsystems, and 2) a simulation process control algorithm to realize the coupling simulation in a spatiotemporal synchronized manner. The test results from a case study show that the proposed method 1) can certainly be used to simulate the sub-systems interactions under different simulation conditions in an engineering system, and 2) effectively supports multi-directional coupling simulation among multi-disciplinary subsystems. This method has been successfully applied in China high speed train design and development processes, demonstrating that it can be applied in a wide range of engineering systems design and simulation with improved efficiency and effectiveness.
文摘This work provides an overview of distillation processes,including process design for different distillation processes,selection of entrainers for special distillation processes,system integration and intensification of distillation processes,optimization of process parameters for distillation processes and recent research progress in dynamic control strategies.Firstly,the feasibility of using thermodynamic topological theories such as residual curve,phase equilibrium line and distillation boundary line to analyze different separation regions is discussed,and the rationality of distillation process design is discussed by using its feasibility.Secondly,the application of molecular simulation methods such as molecular dynamics simulation and quantum chemical calculation in the screening of entrainer is discussed for the extractive distillation process.The thermal coupling mechanism of different distillation processes is used to explore the process of different process intensifications.Next,a mixed integer nonlinear optimization strategy for the distillation process based on different algorithms is introduced.Finally,the improvement of dynamic control strategies for different distillation processes in recent years is summarized.This work focuses on the application of process intensification and system optimization in the design of distillation process,and analyzes the challenges,prospects,and development trends of distillation technology in the separation of multicomponent azeotropes.
基金Supported by the Major State Basic Research Development Program of China(2012CB720500)the National Natural Science Foundation of China(U1162202)+2 种基金the Shanghai Second Polytechnic University Key Discipline Construction(4th term)-Control Theory&Control Engineering(XXKPY1308)the Cultivation Program of Young Teachers in Colleges and Universities of Shanghai(ZZegdl4013)the School Foundation of Shanghai Second Polytechnic University(EGD14XQD02)
文摘The p-xylene(PX) oxidation process is of great industrial importance because of the strong demand of the global polyester fiber.A steady-state model of the PX oxidation has been studied by many researchers.In our previous work,a novel industrial p-xylene oxidation reactor model using the free radical mechanism based kinetics has been developed.However,the disturbances such as production rate change,feed composition variability and reactor temperature changes widely exist in the industry process.In this paper,dynamic simulation of the PX oxidation reactor was designed by Aspen Dynamics and used to develop an effective plantwide control structure,which was capable of effectively handling the disturbances in the load and the temperature of the reactor.Step responses of the control structure to the disturbances were shown and served as the foundation of the smooth operation and advanced control strategy of this process in our future work.
文摘This paper attempts to set a unified scene for various linear time-invariant (LTI) control system design schemes, by transforming the existing concept of “computer-aided control system design” (CACSD) to novel “computer-automated control system design” (CAutoCSD). The first step towards this goal is to accommodate, under practical constraints, various design objectives that are desirable in both time and frequency domains. Such performance-prioritised unification is aimed at relieving practising engineers from having to select a particular control scheme and from sacrificing certain performance goals resulting from pre-commitment to such schemes. With recent progress in evolutionary computing based extra-numeric, multi-criterion search and optimisation techniques, such unification of LTI control schemes becomes feasible, analytical and practical, and the resultant designs can be creative. The techniques developed are applied to, and illustrated by, three design problems. The unified approach automatically provides an integrator for zero-steady state error in velocity control of a DC motor, and meets multiple objectives in the design of an LTI controller for a non-minimum phase plant and offers a high-performance LTI controller network for a non-linear chemical process.
基金Project supported by the Natural Science Foundation of Henan province, China (Grant No 0411011900).
文摘In this paper, the dynamics of coherent laser control of potassium atoms is studied by using the time-dependent multilevel approach (TDMA). The calculation results of population transfer are presented with different laser fields. The results show that the population can be transferred to target state completely by a specially designed laser field.
文摘Objective: This paper takes the example of a Panax notoginseng extraction workshop and designs an automated production workshop with advanced domestic capabilities. Methods: 1) Based on the small-scale Panax notoginseng extraction process, the feasibility of the workshop production process is demonstrated. 2) The workshop process design for Panax Notoginseng saponin extraction is completed, including production organization plans and the selection of key equipment. 3) For the Panax notoginseng extraction workshop process, an automated production control system is designed. Conclusion: Through optimized design of the production process and automation system, continuous and automated production of traditional Chinese medicine extraction is achieved, leading to improvements in drug quality and production efficiency.
文摘The method of designing industrial processes of quench cooling, in particular, the speed of the conveyor movement with regard to shape and sizes of parts to be quenched, thermal and physical properties of material and cooling capacity of quenchants has been developed. The suggested designing method and databases are the basis for the complete automation of industrial processes of quench cooling, especially for continuous conveyor lines, with the purpose of making high-strength materials. The process is controlled by infrared technique.
基金The National Major Scientific and Technological Special Project for‘Significant New Drugs Development’(Grant No.:2017ZX0901001-007)provides support for this study.
文摘From a regulatory perspective,drug quality consistency evaluation must concern different processes used for the same drug.In this study,an assessment strategy based on quality by design(QbD)was developed for population pharmaceutical quality evaluation.A descriptive analysis method based on QbD concept was first established to characterize the process by critical evaluation attributes(CEAs).Then quantitative analysis method based on an improved statistical process control(SPC)method was established to investigate the process indicators(PIs)in the process population,such as mean distribution,batch-to-batch difference and abnormal quality probability.After that rules for risk assessment were established based on the SPC limitations and parameters.Both the SPC parameters of the CEAs and the risk of PIs were visualized according to the interaction test results to obtain a better understanding of the population pharmaceutical quality.Finally,an assessment strategy was built and applied to generic drug consistency assessment,process risk assessment and quality trend tracking.The strategy demonstrated in this study could help reveal quality consistency from the perspective of process control and process risk,and further show the recent development status of domestic pharmaceutical production processes.In addition,a process risk assessment and population quality trend tracking provide databased information for approval.Not only can this information serve as a further basis for decisionmaking by the regulatory authority regarding early warnings,but it can also reduce some avoidable adverse reactions.With continuous addition of data,dynamic population pharmaceutical quality is meaningful for emergencies and decision-making regarding drug regulation.
基金Supported by the Fundamental Research Funds for the Central Universities(04040022212005)
文摘In this paper,effects of conditions in phenol sulfonic acid(PSA) plating for tin coating of MR low carbon aluminum killed steel on trace Pb were examined.Trace Pb was measured by atomic absorption spectrometry(AAS)and glow discharge spectrometry,and coating morphology was observed by scanning electronic microscopy(SEM).Corrosion resistance of the tin coating was analyzed by electrochemical methods.The results indicated that Pb content in the tin coating reduced as bath temperature increased.When the temperature exceeded40 ℃,the grains in the coating were coarse and loose,reducing the corrosion resistance.As current density increased,Pb content increased rapidly,while low current density plating could lead to drain regions.The plating speed had no obvious effect on trace Pb in tin coating.In the tin plating layer,Pb was enriched at the surface and gradually reduced to zero along the depth.At bath temperature of 40 ℃ and current density of 20 A·dm^(-2),the amount of Pb could be less than 100 mg·kg^(-1) with excellent corrosion resistance.
基金Supported by the National Basic Research Program of China(973 Program:2012CB720500)the National Supporting Research Program of China(Grant2013BAA03B01)+2 种基金the National Natural Science Foundation of China(21176178)the China Scholarship Council(201506250011)the China Postdoctoral Science Foundation(2017M620587)
文摘The focus of this paper is to investigate different control structures(single-loop PI control) for a dividing wall(Petlyuk) column for separating ethanol, n-propanol and n-butanol. Four control structures are studied. All the results are simulations based on Aspen Plus. Control structure 1(CS1) is stabilizing control structure with only temperature controllers. CS2, CS3 and CS4, containing also composition controllers, are introduced to reduce the steady state composition deviations. CS2 adds a distillate composition controller(CCDB) on top of CS1. CS3 is much more complicated with three temperature-composition cascade controllers and in addition a selector to the reboiler duty to control the maximum controller output of light impurity composition control in side stream and bottom impurity control in the prefractionator. CS4 adds another high selector to control the light impurity in the sidestream. Surprisingly, when considering the dynamic and even steady state performance of the proposed control structures, CS1 proves to be the best control structure to handle feed disturbances inserted into the three-product Petlyuk column.
基金Supported by Open Research Project of State Key Laboratory of Chemical Engineering(Grant No.SKL-Ch E-16B06)
文摘Dividing wall column(DWC)is shown to be energy efficient compared to conventional column sequence for multi components separation,which is used for olefin separation in fluidization methanol to propylene process in the present work.Detailed design for pilot DWC was performed and five control structures,i.e.composition control(CC),temperature control(TC),composition-temperature control(CC-TC),temperature difference control(TDC),double temperature difference control(DTDC)were proposed to circumvent feed disturbance.Sensitivity analysis and singular value decomposition(SVD)were used as criterion to select the controlled temperature locations in TC,CC-TC,TDC and DTDC control loops.The steady simulation result demonstrates that 25.7% and 30.2% duty can be saved for condenser and reboiler by substituting conventional column sequence with DWC,respectively.As for control structure selection,TC and TDC perform better than other three control schemes with smaller maximum deviation and shorter settling time.
文摘Since Lowry et al. [1992] proposed a multivariate version of theexponentially weighted moving average (EWMA) control chart, the multivariate EWMA control chart hasbecome more and more popular in monitoring production processes, especially in chemical processes.A major advantage of multivariate EWMA statistics is that it is sensitive to small and moderateshifts in the mean vector. However, when a multivariate EWMA chart issues a signal, it is difficultto identify which variable or set of variables is out of control. In this paper, we introduce anew approach to diagnosing signals from a multivariate EWMA control chart. The implementationprocedure is that when the multivariate EWMA control chart issues a signal, we adopt a univariatediagnostic procedure to identify the variables or/and the principal components that caused thesignal.
基金Supported by the National Natural Science Foundation of China(21676152)
文摘Extractive distillation is an effective method for separating azeotropic or close boiling point mixtures by adding a third component.Various technologies for performing the extractive distillation process have been explored to protect the environment and save resources.This paper focuses on the improvement of these advanced technologies in recent years.Extractive distillation is retrieved and analyzed from the view of phase equilibrium,selection of solvent in extractive distillation,process design,energy conservation,and dynamic control.The quantitative structure–property relationship used in extractive distillation is discussed,and the future development of extractive distillation is proposed to determine how the solvent affects the relative volatility of the separated mixture.In the steady state design,the relationship between the curvature of the residue curve and parameters of the optimal steady state is also highlighted as another field worthy of further study to simplify the distillation process.
基金Supported by the National Natural Science Foundation of China(51079107,50839004)the Program for New Century Excellent Talents in University(NCET-09-0610)
文摘Seepage flow through soils,rocks and geotechnical structures has a great influence on their stabilities and performances,and seepage control is a critical technological issue in engineering practices.The physical mechanisms associated with various engineering measures for seepage control are investigated from a new perspective within the framework of continuum mechanics;and an equation-based classification of seepage control mechanisms is proposed according to their roles in the mathematical models for seepage flow,including control mechanisms by coupled processes,initial states,boundary conditions and hydraulic properties.The effects of each mechanism on seepage control are illustrated with examples in hydroelectric engineering and radioactive waste disposal,and hence the reasonability of classification is demonstrated.Advice on performance assessment and optimization design of the seepage control systems in geotechnical engineering is provided,and the suggested procedure would serve as a useful guidance for cost-effective control of seepage flow in various engineering practices.
文摘Crystallization is one of the oldest separation and purification unit operations, and has recently contributed to significant improvements in producing higher-value products with specific properties and in building efficient manufacturing processes. In this paper, we review recent developments in crystal engineering and crystallization process design and control in the pharmaceutical industry. We systematically summarize recent methods for understanding and developing new types of crystals such as co-crystals, polymorphs, and solvates, and include several milestones such as the launch of the first co-crystal drug, Entresto (No- vartis), and the continuous manufacture of Orkambi (Vertex). Conventional batch and continuous processes, which are becoming increasingly mature, are being coupled with various control strategies and the recently developed crystallizers are thus adapting to the needs of the pharmaceutical industry. The development of crystallization process design and control has led to the appearance of several new and innovative crystal- lizer geometries for continuous operation and improved performance. This paper also reviews major recent orogress in the area of process analytical technology.
文摘Achieving Six-Sigma process capability starts with l istening to the Voice of the Customers, and it becomes a reality by combining th e People Power and the Process Power of the organisation. This paper presents a Six-Sigma implementation case study carried out in a magnet manufacturing compa ny, which produces bearing magnets to be used in energy meters. If the thickness of the produced bearing magnets is between 2.35 mm and 2.50 mm, they will be ac cepted by the customers. All the time the company could not produce the bearing magnets within the specified thickness range, as their process distribution was flat with 2.20 mm as lower control limit and 2.60 mm as upper control limit. This resulted in a huge loss in the form of non-conformities, loss of time and goodwill. The process capability of the company then was around 0.40. Organisat ion restructuring was carried out to reap the benefit of the People Power of the organisation. Statistically designed experiments (Taguchi Method based Design o f Experiments), Online quality control tools (Statistical Process Control To ols) were effectively used to complete the DMAIC (Define, Measure, Analyse, Impr ove and Control) cycle to reap the benefit of the Process Power of the organisat ion. Presently the company enjoys a process capability of 1.75, a way towards Si x-Sigma Process Capability.
文摘In this paper, design and fabrication of a commemorative plaque are described and presented. The plaque was fabricated to honour the memory of the 14 women massacred at L'Ecole Polytechnique in Montreal. This plaque is the result of a project partnership between the Faculties of Engineering and Fine Arts, and was sponsored by the Office of the Vice-President Academic and Provost. An art design was selected through a contest coordinated by the Visual Arts Departmment. The selected art design was then turned over to the Mechanical Engineering Department to be converted to a 3-dimensional (3D) solid model and then eventually fabricated on a computer numerical control (CNC) milling machine. The fabricated plaque was unveiled during the December 2010 Memorial event at UVic.