Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts ...Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts and restore texture completely in OCT images.We proposed a deep learning-based inpainting method of saturation artifacts in this paper.The generation mechanism of saturation artifacts was analyzed,and experimental and simulated datasets were built based on the mechanism.Enhanced super-resolution generative adversarial networks were trained by the clear–saturated phantom image pairs.The perfect reconstructed results of experimental zebrafish and thyroid OCT images proved its feasibility,strong generalization,and robustness.展开更多
The importance of the accuracy of preparing biological specimen as histological sections that can be examined under a microscope lies in reflecting a true image of the tissue that includes all its components, which ar...The importance of the accuracy of preparing biological specimen as histological sections that can be examined under a microscope lies in reflecting a true image of the tissue that includes all its components, which are used in scientific research or for the purpose of diagnosing various diseases of the body. Despite this, some cellular structures within the tissue may suffer from some alterations that result from the appearance of defects during any stage of preparing these microscopic sections, which alter or interfere with the precise cellular structures and morphology that constitute the tissue and thus give a different image for tissue features and cause confusion in the work histopathologist in the diagnosis. There are several reasons that can cause a misdiagnosis of the sample that occurs during the surgical separation process or after separation during the stages of microscopic preparation techniques from fixation stage, tissue processing, embedding or microtomy, staining until mounting procedures. The constant need to identify these defects and their causes in addition to try to reduce them is one of the biggest challenges evident in pathology laboratories. Therefore, this study aims to review the most common defects that occur in any stage of tissue processing, with an explanation of their causes and appropriate ways to avoid them.展开更多
Optical coherence tomography(OCT)imaging technology has significant advantages in in situ and noninvasive monitoring of biological tissues.However,it still faces the following challenges:including data processing spee...Optical coherence tomography(OCT)imaging technology has significant advantages in in situ and noninvasive monitoring of biological tissues.However,it still faces the following challenges:including data processing speed,image quality,and improvements in three-dimensional(3D)visualization effects.OCT technology,especially functional imaging techniques like optical coherence tomography angiography(OCTA),requires a long acquisition time and a large data size.Despite the substantial increase in the acquisition speed of swept source optical coherence tomography(SS-OCT),it still poses significant challenges for data processing.Additionally,during in situ acquisition,image artifacts resulting from interface reflections or strong reflections from biological tissues and culturing containers present obstacles to data visualization and further analysis.Firstly,a customized frequency domainfilter with anti-banding suppression parameters was designed to suppress artifact noises.Then,this study proposed a graphics processing unit(GPU)-based real-time data processing pipeline for SS-OCT,achieving a measured line-process rate of 800 kHz for 3D fast and high-quality data visualization.Furthermore,a GPU-based realtime data processing for CC-OCTA was integrated to acquire dynamic information.Moreover,a vascular-like network chip was prepared using extrusion-based 3D printing and sacrificial materials,with sacrificial material being printed at the desired vascular network locations and then removed to form the vascular-like network.OCTA imaging technology was used to monitor the progression of sacrificial material removal and vascular-like network formation.Therefore,GPU-based OCT enables real-time processing and visualization with artifact suppression,making it particularly suitable for in situ noninvasive longitudinal monitoring of 3D bioprinting tissue and vascular-like networks in microfluidic chips.展开更多
Digital forensics aims to uncover evidence of cybercrimes within compromised systems.These cybercrimes are often perpetrated through the deployment of malware,which inevitably leaves discernible traces within the comp...Digital forensics aims to uncover evidence of cybercrimes within compromised systems.These cybercrimes are often perpetrated through the deployment of malware,which inevitably leaves discernible traces within the compromised systems.Forensic analysts are tasked with extracting and subsequently analyzing data,termed as artifacts,from these systems to gather evidence.Therefore,forensic analysts must sift through extensive datasets to isolate pertinent evidence.However,manually identifying suspicious traces among numerous artifacts is time-consuming and labor-intensive.Previous studies addressed such inefficiencies by integrating artificial intelligence(AI)technologies into digital forensics.Despite the efforts in previous studies,artifacts were analyzed without considering the nature of the data within them and failed to prove their efficiency through specific evaluations.In this study,we propose a system to prioritize suspicious artifacts from compromised systems infected with malware to facilitate efficient digital forensics.Our system introduces a double-checking method that recognizes the nature of data within target artifacts and employs algorithms ideal for anomaly detection.The key ideas of this method are:(1)prioritize suspicious artifacts and filter remaining artifacts using autoencoder and(2)further prioritize suspicious artifacts and filter remaining artifacts using logarithmic entropy.Our evaluation demonstrates that our system can identify malicious artifacts with high accuracy and that its double-checking method is more efficient than alternative approaches.Our system can significantly reduce the time required for forensic analysis and serve as a reference for future studies.展开更多
This study addresses challenges in fetal magnetic resonance imaging (MRI) related to motion artifacts, maternal respiration, and hardware limitations. To enhance MRI quality, we employ deep learning techniques, specif...This study addresses challenges in fetal magnetic resonance imaging (MRI) related to motion artifacts, maternal respiration, and hardware limitations. To enhance MRI quality, we employ deep learning techniques, specifically utilizing Cycle GAN. Synthetic pairs of images, simulating artifacts in fetal MRI, are generated to train the model. Our primary contribution is the use of Cycle GAN for fetal MRI restoration, augmented by artificially corrupted data. We compare three approaches (supervised Cycle GAN, Pix2Pix, and Mobile Unet) for artifact removal. Experimental results demonstrate that the proposed supervised Cycle GAN effectively removes artifacts while preserving image details, as validated through Structural Similarity Index Measure (SSIM) and normalized Mean Absolute Error (MAE). The method proves comparable to alternatives but avoids the generation of spurious regions, which is crucial for medical accuracy.展开更多
This study presents an energy consumption(EC)forecasting method for laser melting manufacturing of metal artifacts based on fusionable transfer learning(FTL).To predict the EC of manufacturing products,particularly fr...This study presents an energy consumption(EC)forecasting method for laser melting manufacturing of metal artifacts based on fusionable transfer learning(FTL).To predict the EC of manufacturing products,particularly from scale-down to scale-up,a general paradigm was first developed by categorizing the overall process into three main sub-steps.The operating electrical power was further formulated as a combinatorial function,based on which an operator learning network was adopted to fit the nonlinear relations between the fabricating arguments and EC.Parallel-arranged networks were constructed to investigate the impacts of fabrication variables and devices on power.Considering the interconnections among these factors,the outputs of the neural networks were blended and fused to jointly predict the electrical power.Most innovatively,large artifacts can be decomposed into timedependent laser-scanning trajectories,which can be further transformed into fusionable information via neural networks,inspired by large language model.Accordingly,transfer learning can deal with either scale-down or scale-up forecasting,namely,FTL with scalability within artifact structures.The effectiveness of the proposed FTL was verified through physical fabrication experiments via laser powder bed fusion.The relative error of the average and overall EC predictions based on FTL was maintained below 0.83%.The melting fusion quality was examined using metallographic diagrams.The proposed FTL framework can forecast the EC of scaled structures,which is particularly helpful in price estimation and quotation of large metal products towards carbon peaking and carbon neutrality.展开更多
业务流程是组合服务的主要表现形式之一.跨组织多方协作流程往往包含多重粒度,难以基于任何单一粒度建模.Proclets方法将多粒度单体流程分解为一组交互协作的单粒度流程,以实例的基数、多重性来约束其间的交互关系.然而,在此类方法中如...业务流程是组合服务的主要表现形式之一.跨组织多方协作流程往往包含多重粒度,难以基于任何单一粒度建模.Proclets方法将多粒度单体流程分解为一组交互协作的单粒度流程,以实例的基数、多重性来约束其间的交互关系.然而,在此类方法中如何体现流程业务目标与业务进展,支持复杂且多变的协作关系,准确刻画模型的执行语义等问题尚缺乏有效的建模技术.提出一种以Artifact为中心的多粒度协作流程建模方法 Arti Mate:继承proclets的粒度分解思路但以Artifact为中心建模各单粒度流程artilet,利于刻画业务目标,追踪业务进展;解耦交互机制和交互策略,以丰富、插件式交互策略polilet连接较为稳定的artilet,复用实质性业务流程并适应协作需求变化;以着色Petri网描述的Arti Mate的执行语义,有利于建模方法的实现和仿真确认.论文以国家海洋局东海分局会签类应用为案例,检验了Arti Mate方法的可行性和有效性.展开更多
To solve the problem that metal artifacts severely damage the clarity of the organization structure in computed tomography(CT) images, a sinogram fusion-based metal artifact correction method is proposed. First, the...To solve the problem that metal artifacts severely damage the clarity of the organization structure in computed tomography(CT) images, a sinogram fusion-based metal artifact correction method is proposed. First, the metal image is segmented from the original CT image by the pre-set threshold. The original CT image and metal image are forward projected into the original projection sinogram and metal projection sinogram, respectively. The interpolation-based correction method and mean filter are used to correct the original CT image and preserve the edge of the corrected CT image, respectively. The filtered CT image is forward projected into the filtered image sinogram. According to the position of the metal sinogram in the original sinogram and filtered image sinogram, the corresponding sinograms PM^D ( in the original sinogram) and PM^C ( in the filtered image sinogram)can be acquired from the original sinogram and filtered image sinogram, respectively. Then, PM^D and PM^C are fused into the fused metal sinogram PM^F according to a certain proportion.The final sinogram can be acquired by fusing PM^F , PM^D and the original sinogram P^O. Finally, the final sinogram is reconstructed into the corrected CT image and metal information is compensated into the corrected CT image.Experiments on clinical images demonstrate that the proposed method can effectively reduce metal artifacts. A comparison with classical metal artifacts correction methods shows that the proposed metal artifacts correction method performs better in metal artifacts suppression and tissue feature preservation.展开更多
基金supported by the National Natural Science Foundation of China(62375144 and 61875092)Tianjin Foundation of Natural Science(21JCYBJC00260)Beijing-Tianjin-Hebei Basic Research Cooperation Special Program(19JCZDJC65300).
文摘Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts and restore texture completely in OCT images.We proposed a deep learning-based inpainting method of saturation artifacts in this paper.The generation mechanism of saturation artifacts was analyzed,and experimental and simulated datasets were built based on the mechanism.Enhanced super-resolution generative adversarial networks were trained by the clear–saturated phantom image pairs.The perfect reconstructed results of experimental zebrafish and thyroid OCT images proved its feasibility,strong generalization,and robustness.
文摘The importance of the accuracy of preparing biological specimen as histological sections that can be examined under a microscope lies in reflecting a true image of the tissue that includes all its components, which are used in scientific research or for the purpose of diagnosing various diseases of the body. Despite this, some cellular structures within the tissue may suffer from some alterations that result from the appearance of defects during any stage of preparing these microscopic sections, which alter or interfere with the precise cellular structures and morphology that constitute the tissue and thus give a different image for tissue features and cause confusion in the work histopathologist in the diagnosis. There are several reasons that can cause a misdiagnosis of the sample that occurs during the surgical separation process or after separation during the stages of microscopic preparation techniques from fixation stage, tissue processing, embedding or microtomy, staining until mounting procedures. The constant need to identify these defects and their causes in addition to try to reduce them is one of the biggest challenges evident in pathology laboratories. Therefore, this study aims to review the most common defects that occur in any stage of tissue processing, with an explanation of their causes and appropriate ways to avoid them.
基金supported by the National Key Research and Development Program of China(Nos.2022YFA1104600 and 2022YFA1200208)National Natural Science Foundation of China(No.31927801)Key Research and Development Foundation of Zhejiang Province(No.2022C01123).
文摘Optical coherence tomography(OCT)imaging technology has significant advantages in in situ and noninvasive monitoring of biological tissues.However,it still faces the following challenges:including data processing speed,image quality,and improvements in three-dimensional(3D)visualization effects.OCT technology,especially functional imaging techniques like optical coherence tomography angiography(OCTA),requires a long acquisition time and a large data size.Despite the substantial increase in the acquisition speed of swept source optical coherence tomography(SS-OCT),it still poses significant challenges for data processing.Additionally,during in situ acquisition,image artifacts resulting from interface reflections or strong reflections from biological tissues and culturing containers present obstacles to data visualization and further analysis.Firstly,a customized frequency domainfilter with anti-banding suppression parameters was designed to suppress artifact noises.Then,this study proposed a graphics processing unit(GPU)-based real-time data processing pipeline for SS-OCT,achieving a measured line-process rate of 800 kHz for 3D fast and high-quality data visualization.Furthermore,a GPU-based realtime data processing for CC-OCTA was integrated to acquire dynamic information.Moreover,a vascular-like network chip was prepared using extrusion-based 3D printing and sacrificial materials,with sacrificial material being printed at the desired vascular network locations and then removed to form the vascular-like network.OCTA imaging technology was used to monitor the progression of sacrificial material removal and vascular-like network formation.Therefore,GPU-based OCT enables real-time processing and visualization with artifact suppression,making it particularly suitable for in situ noninvasive longitudinal monitoring of 3D bioprinting tissue and vascular-like networks in microfluidic chips.
基金supported by the MSIT(Ministry of Science and ICT),Korea,under the ITRC(Information Technology Research Center)support program(IITP-2024-RS-2024-00437494)supervised by the IITP(Institute for Information&Communications Technology Planning&Evaluation).
文摘Digital forensics aims to uncover evidence of cybercrimes within compromised systems.These cybercrimes are often perpetrated through the deployment of malware,which inevitably leaves discernible traces within the compromised systems.Forensic analysts are tasked with extracting and subsequently analyzing data,termed as artifacts,from these systems to gather evidence.Therefore,forensic analysts must sift through extensive datasets to isolate pertinent evidence.However,manually identifying suspicious traces among numerous artifacts is time-consuming and labor-intensive.Previous studies addressed such inefficiencies by integrating artificial intelligence(AI)technologies into digital forensics.Despite the efforts in previous studies,artifacts were analyzed without considering the nature of the data within them and failed to prove their efficiency through specific evaluations.In this study,we propose a system to prioritize suspicious artifacts from compromised systems infected with malware to facilitate efficient digital forensics.Our system introduces a double-checking method that recognizes the nature of data within target artifacts and employs algorithms ideal for anomaly detection.The key ideas of this method are:(1)prioritize suspicious artifacts and filter remaining artifacts using autoencoder and(2)further prioritize suspicious artifacts and filter remaining artifacts using logarithmic entropy.Our evaluation demonstrates that our system can identify malicious artifacts with high accuracy and that its double-checking method is more efficient than alternative approaches.Our system can significantly reduce the time required for forensic analysis and serve as a reference for future studies.
文摘This study addresses challenges in fetal magnetic resonance imaging (MRI) related to motion artifacts, maternal respiration, and hardware limitations. To enhance MRI quality, we employ deep learning techniques, specifically utilizing Cycle GAN. Synthetic pairs of images, simulating artifacts in fetal MRI, are generated to train the model. Our primary contribution is the use of Cycle GAN for fetal MRI restoration, augmented by artificially corrupted data. We compare three approaches (supervised Cycle GAN, Pix2Pix, and Mobile Unet) for artifact removal. Experimental results demonstrate that the proposed supervised Cycle GAN effectively removes artifacts while preserving image details, as validated through Structural Similarity Index Measure (SSIM) and normalized Mean Absolute Error (MAE). The method proves comparable to alternatives but avoids the generation of spurious regions, which is crucial for medical accuracy.
基金funded by the National Key Research and Development Program of China,No.2022YFB3303303Key Open Fund of State Key Lab of Materials Processing and Die&Mould Technology of China,No.P2024-001Zhejiang Provincial Research and Development Project of China,No.LGG22E050010。
文摘This study presents an energy consumption(EC)forecasting method for laser melting manufacturing of metal artifacts based on fusionable transfer learning(FTL).To predict the EC of manufacturing products,particularly from scale-down to scale-up,a general paradigm was first developed by categorizing the overall process into three main sub-steps.The operating electrical power was further formulated as a combinatorial function,based on which an operator learning network was adopted to fit the nonlinear relations between the fabricating arguments and EC.Parallel-arranged networks were constructed to investigate the impacts of fabrication variables and devices on power.Considering the interconnections among these factors,the outputs of the neural networks were blended and fused to jointly predict the electrical power.Most innovatively,large artifacts can be decomposed into timedependent laser-scanning trajectories,which can be further transformed into fusionable information via neural networks,inspired by large language model.Accordingly,transfer learning can deal with either scale-down or scale-up forecasting,namely,FTL with scalability within artifact structures.The effectiveness of the proposed FTL was verified through physical fabrication experiments via laser powder bed fusion.The relative error of the average and overall EC predictions based on FTL was maintained below 0.83%.The melting fusion quality was examined using metallographic diagrams.The proposed FTL framework can forecast the EC of scaled structures,which is particularly helpful in price estimation and quotation of large metal products towards carbon peaking and carbon neutrality.
文摘业务流程是组合服务的主要表现形式之一.跨组织多方协作流程往往包含多重粒度,难以基于任何单一粒度建模.Proclets方法将多粒度单体流程分解为一组交互协作的单粒度流程,以实例的基数、多重性来约束其间的交互关系.然而,在此类方法中如何体现流程业务目标与业务进展,支持复杂且多变的协作关系,准确刻画模型的执行语义等问题尚缺乏有效的建模技术.提出一种以Artifact为中心的多粒度协作流程建模方法 Arti Mate:继承proclets的粒度分解思路但以Artifact为中心建模各单粒度流程artilet,利于刻画业务目标,追踪业务进展;解耦交互机制和交互策略,以丰富、插件式交互策略polilet连接较为稳定的artilet,复用实质性业务流程并适应协作需求变化;以着色Petri网描述的Arti Mate的执行语义,有利于建模方法的实现和仿真确认.论文以国家海洋局东海分局会签类应用为案例,检验了Arti Mate方法的可行性和有效性.
基金Open Research Fund of the Key Laboratory of Computer Netw ork and Information Integration of Ministry of Education of Southeast University(No.K93-9-2014-10C)the Scientific Research Foundation of Education Department of Anhui Province(No.KJ2014A186,SK2015A433)the National Basic Research Program of China(973 Program)(No.2010CB732503)
文摘To solve the problem that metal artifacts severely damage the clarity of the organization structure in computed tomography(CT) images, a sinogram fusion-based metal artifact correction method is proposed. First, the metal image is segmented from the original CT image by the pre-set threshold. The original CT image and metal image are forward projected into the original projection sinogram and metal projection sinogram, respectively. The interpolation-based correction method and mean filter are used to correct the original CT image and preserve the edge of the corrected CT image, respectively. The filtered CT image is forward projected into the filtered image sinogram. According to the position of the metal sinogram in the original sinogram and filtered image sinogram, the corresponding sinograms PM^D ( in the original sinogram) and PM^C ( in the filtered image sinogram)can be acquired from the original sinogram and filtered image sinogram, respectively. Then, PM^D and PM^C are fused into the fused metal sinogram PM^F according to a certain proportion.The final sinogram can be acquired by fusing PM^F , PM^D and the original sinogram P^O. Finally, the final sinogram is reconstructed into the corrected CT image and metal information is compensated into the corrected CT image.Experiments on clinical images demonstrate that the proposed method can effectively reduce metal artifacts. A comparison with classical metal artifacts correction methods shows that the proposed metal artifacts correction method performs better in metal artifacts suppression and tissue feature preservation.