AIM:To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions. MET...AIM:To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions. METHODS:The present study included 108 diabetic retinopathy (DR) patients:54 with PDR and 54 with non-proliferative diabetic retinopathy (NPDR). Each healthy control group (n =54) sociodemographically matched to DR groups was established respectively. The quality of life, anxiety and depression symptoms were evaluated and analyzed on preoperative and postoperative month 1 using SF-36, DSQL and Hospital Anxiety and Depression Scale (HADS). · RESULTS:DR patients described impaired HRQL (Health Related Quality of life, SF -36) in 6 out of 8 subscales, including ‘Body Health’, ‘Body RoleFunction’,‘General Health’,‘Society Function’,‘Emotion Role Function’and‘Mental Health’. Compared with controls, DR patients (NPDR and PDR) suffered from statistically significantly impaired HRQL (SF-36 Summary score) (P【 0.05). By surgical intervention, the anxiety and depression score were significantly reduced, while the health and quality of life (SF-36 Summary scores and DSQL scores) was improved in patients with PDR (P 【0.05). CONCLUSION:DR patients were affected in mentation and quality of life. Surgery interventions can improve SF-36, DSQL, anxiety and depression in PDR patients.展开更多
以《第一批罕见病目录》121种疾病名称为基础,检索中英文数据库(中国知网、万方数据库、PubMed和Web of Science)和患者报告的临床结局和生存质量量表的数据库(PROQOLID),收集并评价罕见病特异性生命质量(quality of life,QoL)量表的研...以《第一批罕见病目录》121种疾病名称为基础,检索中英文数据库(中国知网、万方数据库、PubMed和Web of Science)和患者报告的临床结局和生存质量量表的数据库(PROQOLID),收集并评价罕见病特异性生命质量(quality of life,QoL)量表的研制、测量性能测评及应用文献。现有罕见病特异性生命质量量表50个,其中9个是汉化量表,仅1个量表为国内研制;大部分量表(86.0%)研究对象为成年患者;量表反应度和灵敏度测评较少。建议应加强罕见病生命质量量表尤其是未成年特异性生命质量量表的研制与应用,在量表测量性能评价时重视对反应度和灵敏度的研究。展开更多
基金National Natural Science Foundation of China (No.81160118,81100648,81101858)Clinical Medicine Research Special-purpose Foundation of China (No.L2012052)+4 种基金Natural Science Foundation of Jiangxi Province.China (No.20114BAB215029)Technology Foundation of Jiangxi Province, China (No.20111BBG70026-2)Health Department Science and Technology Foundation of Jiangxi Province, China (No.20121026)Education Department Youth Scientific Research Foundation of Jiangxi Province, China(No.GJJ12158)National High Technology Research (863 project) of China (No. 2006AA02A131)
文摘AIM:To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions. METHODS:The present study included 108 diabetic retinopathy (DR) patients:54 with PDR and 54 with non-proliferative diabetic retinopathy (NPDR). Each healthy control group (n =54) sociodemographically matched to DR groups was established respectively. The quality of life, anxiety and depression symptoms were evaluated and analyzed on preoperative and postoperative month 1 using SF-36, DSQL and Hospital Anxiety and Depression Scale (HADS). · RESULTS:DR patients described impaired HRQL (Health Related Quality of life, SF -36) in 6 out of 8 subscales, including ‘Body Health’, ‘Body RoleFunction’,‘General Health’,‘Society Function’,‘Emotion Role Function’and‘Mental Health’. Compared with controls, DR patients (NPDR and PDR) suffered from statistically significantly impaired HRQL (SF-36 Summary score) (P【 0.05). By surgical intervention, the anxiety and depression score were significantly reduced, while the health and quality of life (SF-36 Summary scores and DSQL scores) was improved in patients with PDR (P 【0.05). CONCLUSION:DR patients were affected in mentation and quality of life. Surgery interventions can improve SF-36, DSQL, anxiety and depression in PDR patients.
文摘以《第一批罕见病目录》121种疾病名称为基础,检索中英文数据库(中国知网、万方数据库、PubMed和Web of Science)和患者报告的临床结局和生存质量量表的数据库(PROQOLID),收集并评价罕见病特异性生命质量(quality of life,QoL)量表的研制、测量性能测评及应用文献。现有罕见病特异性生命质量量表50个,其中9个是汉化量表,仅1个量表为国内研制;大部分量表(86.0%)研究对象为成年患者;量表反应度和灵敏度测评较少。建议应加强罕见病生命质量量表尤其是未成年特异性生命质量量表的研制与应用,在量表测量性能评价时重视对反应度和灵敏度的研究。
