We propose and study an iterative sparse reconstruction for Fourier domain optical coherence tomography （FD OCT） image by solving a constrained optimization problem that minimizes L-1 norm. Our method takes the spec...We propose and study an iterative sparse reconstruction for Fourier domain optical coherence tomography （FD OCT） image by solving a constrained optimization problem that minimizes L-1 norm. Our method takes the spectral shape of the OCT light source into consideration in the iterative image reconstruction procedure that allows deconvolution of the axial point spread function from the blurred image during reconstruction rather than after reconstruction. By minimizing the L-1 norm, the axial resolution and the signal to noise ratio of image can both be enhanced. The effectiveness of our method is validated using numerical simulation and experiment.展开更多
Optical Coherence Tomography (OCT) technique is a nondestructive optical detection technology based on low-coherence interferometer and it has become an attractive cultural heritage research method. A 1310 nm source s...Optical Coherence Tomography (OCT) technique is a nondestructive optical detection technology based on low-coherence interferometer and it has become an attractive cultural heritage research method. A 1310 nm source spectral-domain optical coherence tomography (SD-OCT) system based on optical fiber Michelson interferometer and optical spectrum analyzer is proposed and demonstrated for Chinese cultural heritage research. The cross-section OCT images of Chinese pigment samples and jadeite samples can provide a lot of valuable microstructure information for the Chinese cultural heritage research and identification works.展开更多
Spectral domain optical coherence tomography(SDOCT)is a noninvasive,cross-sectional imaging technique that measures depth resolved reflectance of tissue by Fourier transforming the spectral interferogram with the scan...Spectral domain optical coherence tomography(SDOCT)is a noninvasive,cross-sectional imaging technique that measures depth resolved reflectance of tissue by Fourier transforming the spectral interferogram with the scanning of the reference avoided.Interferometric synthetic aperture microscopy(ISAM)is an optical microscopy computed-imaging technique for measuring the optical properties of biological tissues,which can overcome the compromise between depth of focus and transverse resolution.This paper describes the principle of SDOCT and ISAM,which multiplexes raw acquisitions to provide quantitatively meaningful data with reliable spatially invariant resolution at all depths.A mathematical model for a coherent microscope with a planar scanning geometry and spectral detection was described.The two-dimensional fast Fourier transform(FFT)of spectral data in the transverse directions was calculated.Then the nonuniform ISAM resampling and filtering was implemented to yield the scattering potential within the scalar model.Inverse FFT was used to obtain the ISAM reconstruction.One scatterer,multiple scatterers,and noisy simulations were implemented by use of ISAM to catch spatially invariant resolution.ISAM images were compared to those obtained using standard optical coherence tomography(OCT)methods.The high quality of the results validates the rationality of the founded model and that diffraction limited resolution can be achieved outside the focal plane.展开更多
基金supported in part by the government of United States,NIH BRP grants 1R01 EB 007969NIH/NIE R011R01EY021540-01A1,and by internal start-up research funding from Michigan Technological University
文摘We propose and study an iterative sparse reconstruction for Fourier domain optical coherence tomography （FD OCT） image by solving a constrained optimization problem that minimizes L-1 norm. Our method takes the spectral shape of the OCT light source into consideration in the iterative image reconstruction procedure that allows deconvolution of the axial point spread function from the blurred image during reconstruction rather than after reconstruction. By minimizing the L-1 norm, the axial resolution and the signal to noise ratio of image can both be enhanced. The effectiveness of our method is validated using numerical simulation and experiment.
文摘Optical Coherence Tomography (OCT) technique is a nondestructive optical detection technology based on low-coherence interferometer and it has become an attractive cultural heritage research method. A 1310 nm source spectral-domain optical coherence tomography (SD-OCT) system based on optical fiber Michelson interferometer and optical spectrum analyzer is proposed and demonstrated for Chinese cultural heritage research. The cross-section OCT images of Chinese pigment samples and jadeite samples can provide a lot of valuable microstructure information for the Chinese cultural heritage research and identification works.
文摘Spectral domain optical coherence tomography(SDOCT)is a noninvasive,cross-sectional imaging technique that measures depth resolved reflectance of tissue by Fourier transforming the spectral interferogram with the scanning of the reference avoided.Interferometric synthetic aperture microscopy(ISAM)is an optical microscopy computed-imaging technique for measuring the optical properties of biological tissues,which can overcome the compromise between depth of focus and transverse resolution.This paper describes the principle of SDOCT and ISAM,which multiplexes raw acquisitions to provide quantitatively meaningful data with reliable spatially invariant resolution at all depths.A mathematical model for a coherent microscope with a planar scanning geometry and spectral detection was described.The two-dimensional fast Fourier transform(FFT)of spectral data in the transverse directions was calculated.Then the nonuniform ISAM resampling and filtering was implemented to yield the scattering potential within the scalar model.Inverse FFT was used to obtain the ISAM reconstruction.One scatterer,multiple scatterers,and noisy simulations were implemented by use of ISAM to catch spatially invariant resolution.ISAM images were compared to those obtained using standard optical coherence tomography(OCT)methods.The high quality of the results validates the rationality of the founded model and that diffraction limited resolution can be achieved outside the focal plane.
