Aim: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). Methods: A total of 582 traces of pressu...Aim: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). Methods: A total of 582 traces of pressure-flow study from 181 men with BPH was included in the study. For each trace, maximum urinary flow rate (Qmax) and detrusor pressure at Qmax (pdet.Qmax) were, respectively, read from manually smoothed and corrected uroflow and detrusor pressure curves from the computer print-outs. Obstruction coefficient, International Continence Society (ICS) and Schaefer nomograms were used to detect urethral resistance and to diagnose obstruction. The results obtained by manual reading were compared with those from computer-based systems. Results: After manual correction, Qmax underwent a consistently significant decrease by 1.2 mL/s on average (P 〈 0.001), and had a change range of 0.5-10.4 mL/s. However, pdet.Qmax underwent inconsistently intra-individual changes after correction. The obstruction coefficient increased significantly, by an average of 0.07 (P 〈 0.05). Using the ICS nomogram, the percentage of obstruction increased from 69.8% to 73.9%, and of the non-obstruction decreased from 8.8% to 5.3% (P 〈 0.05). There were 11% of traces that changed the classifications using the ICS nomogram, and 28.9% that changed the grades for the Schaefer nomogram. Conclusion: Systematically significant differences in parameters from pres- sure-flow study between manual readings and computer recordings were demonstrated. Manual correction resulted in a consistently lower Q a higher urethral resistance, and an aggravating obstruction. Manual readings can correct considerable false diagnoses for obstruction. Retrospective quality control of pressure-flow data with com- puter-based systems is necessary.展开更多
For the congestion problems in high-speed networks, a genetic based fuzzy Q-learning flow controller is proposed. Because of the uncertainties and highly time-varying, it is not easy to accurately obtain the complete ...For the congestion problems in high-speed networks, a genetic based fuzzy Q-learning flow controller is proposed. Because of the uncertainties and highly time-varying, it is not easy to accurately obtain the complete information for high-speed networks. In this case, the Q-learning, which is independent of mathematic model, and prior-knowledge, has good performance. The fuzzy inference is introduced in order to facilitate generalization in large state space, and the genetic operators are used to obtain the consequent parts of fuzzy rules. Simulation results show that the proposed controller can learn to take the best action to regulate source flow with the features of high throughput and low packet loss ratio, and can avoid the occurrence of congestion effectively.展开更多
In order to eliminate mal-distribution and ensure the side arm to produce desirable gas quality a special distributor is proposed. The experimental distributor mainly consists of a straight through section,a gas extra...In order to eliminate mal-distribution and ensure the side arm to produce desirable gas quality a special distributor is proposed. The experimental distributor mainly consists of a straight through section,a gas extraction line,a liquid extraction line and a side arm branch. A gas orifice and a liquid orifice are mounted at the gas and liquid extraction line respectively to control the outlet gas quality. The diameter of the liquid orifice was set to 2. 50 mm and three gas orifices with different size( dG= 2. 65,5. 00,10. 00 mm) were tested. The experiments were carried out at an air-water two-phase flow loop. The gas superficial velocity ranged from 6. 0 to 20. 0 m /s and the liquid superficial velocity was in the range of 0. 02- 0. 18 m /s. Flow patterns such as wave flow,slug flow and annular flow were observed. The gas quality of the side arm branch was found mainly determined by the flow area ratio of the gas orifice to the liquid orifice and independent of gas and liquid superficial velocity,flow patterns and extraction flux.展开更多
cytometric immunophenotyping has evolved from two-parameter quantitative measurement of peripheral blood lymphocytes to five-or more parameter qualitative evaluation of bone marrow for hematopathology.Leukemia/lymphom...cytometric immunophenotyping has evolved from two-parameter quantitative measurement of peripheral blood lymphocytes to five-or more parameter qualitative evaluation of bone marrow for hematopathology.Leukemia/lymphoma immunophenotyping represent an important addition to histomorphology in the diagnosis,classification and monitoring of hematolymphoid neoplasms.The complexity of five-or more parameter analyses and the interpretation of the data rely on standardization and validation of the instrument,the reagent and the procedure.In addition,clinical flow cytometry laboratories in U.S.are required to document proficiency testing,sample preparation,method accuracy,specificity,sensitivity and precision.CLSI and the U.S.-Canadian Consensus Conference have provided recommendations,but each laboratory is responsible for validating its own qualitative and quantitative procedures.This paper introduces the procedures for quality control of all levels of the operation in a clinical flow cytometry laboratory in USA.展开更多
Objective: Vein graft quality control had been traditionally done for more than 20 years with a roller-pump flow measurement (RPFM) in our institute until off-pump coronary artery bypass grafting was introduced as the...Objective: Vein graft quality control had been traditionally done for more than 20 years with a roller-pump flow measurement (RPFM) in our institute until off-pump coronary artery bypass grafting was introduced as the standard technique of myocardial revascularization in the year 2009 in our institute. In this study, the RPFM method was compared with the Transit-time flow measurement (TTFM). Patients and Methods: From February to September 2005, 31 patients (5 females) undergoing CABG in our institute were included into the study. All the patients were operated with cardiopulmonary bypass. In those patients, 27 distal anastomoses were done with the left internal thoracic artery and 99 anastomoses were done with vein grafts. Those 99 vein graft were assessed both, with the RPFM method and TTFM method. Results: CABG could be safely performed in all cases. In all target vessels, the RPFM method overestimated bypass flow compared to the TTFM method, and simple linear regression revealed no correlation between the TTFM measurement and the RPFM measurement (r = 0.08, p = 0.21). There were two cases in which a graft problem could be detected only with TTFM method, even in our small patient cohort. Conclusion: The present study suggests that the TTFM method is clearly superior to the traditional RPFM method and we believe now that TTFM should be performed routinely in all CABG to improve patient care and quality of surgical results.展开更多
The optimum control strategy and the saving potential of all variable chiller plant under the conditions of changing building cooling load and cooling water supply temperature were investigated. Based on a simulation ...The optimum control strategy and the saving potential of all variable chiller plant under the conditions of changing building cooling load and cooling water supply temperature were investigated. Based on a simulation model of water source chiller plant established in dynamic transient simulation program (TRNSYS),the four-variable quadratic orthogonal regression experiments were carried out by taking cooling load,cooling water supply temperature,cooling water flow rate and chilled water flow rate as variables,and the fitting formulas expressing the relationships between the total energy consumption of chiller plant with the four selected parameters was obtained. With the SAS statistical software and MATHEMATICA mathematical software,the optimal chilled water flow rate and cooling water flow rate which result in the minimum total energy consumption were determined under continuously varying cooling load and cooling water supply temperature. With regard to a chiller plant serving an office building in Shanghai,the total energy consumptions under different control strategies were computed in terms of the forecasting function of cooling load and water source temperature. The results show that applying the optimal control strategy to the chiller plant can bring a saving of 23.27% in power compared with the corresponding conventional variable speed plant,indicating that the optimal control strategy can improve the energy efficiency of chiller plant.展开更多
In this paper, a novel flow control mechanism in cognitive packet network (CPN) based on the improved back propagation (BP) neural network is proposed, considering the flow distribution status predicted by BP neural n...In this paper, a novel flow control mechanism in cognitive packet network (CPN) based on the improved back propagation (BP) neural network is proposed, considering the flow distribution status predicted by BP neural network when packets are routed. The objective is to increase the capacity of CPN and improve the quality of service (QoS) by achieving flow balance. Besides, considering the slow convergence speed of traditional BP algorithm and the quick change of the flow status in cognitive packet network, an improved BP algorithm with dynamic learning rate is designed in order to achieve a higher convergence speed. The mechanism, which we propose, regards the predicated traffic data as an important factor when packets are routed to implement flow control. By achieving balance, the quality of network can be improved obviously. The simulation results show that the proposed mechanism provides better average time delay and packets loss ratio.展开更多
In this work, the authors propose the study of a wind speed variable based on the DFAM (double fed asynchronous machine). The model of the turbine is drawn from the classical equations describing the operation of a ...In this work, the authors propose the study of a wind speed variable based on the DFAM (double fed asynchronous machine). The model of the turbine is drawn from the classical equations describing the operation of a variable wind speed. The torque generated by the turbine is applied to the DFAM directly connected on the network side and the stator via a bidirectional converter side rotor. This configuration allows velocity variations of ±30% around the synchronous speed and the converter is then sized to one third of the rated power of the machine. The DFAM is controlled by a control vector ensuring operation of the wind turbine power coefficient maximum.展开更多
The Chicago Area Waterway System(CAWS)is a 133.9 km branching network of navigable waterways controlled by hydraulic structures,in which the majority of the flow is treated wastewater effluent and there are periods of...The Chicago Area Waterway System(CAWS)is a 133.9 km branching network of navigable waterways controlled by hydraulic structures,in which the majority of the flow is treated wastewater effluent and there are periods of substantial combined sewer overflows.The CAWS comprises a network of effluent dominated streams.More stringent dissolved oxygen(DO)standards and a reduced flow augmentation allowance have been recently applied to the CAWS.Therefore,a carefully calibrated and verified one-dimensional flow and water quality model was applied to the CAWS to determine emission-based real-time control guidelines for the operation of flow augmentation and aeration stations.The goal of these guidelines was to attain DO standards at least 95%of the time.The“optimal”guidelines were tested for representative normal,dry,and wet years.The finally proposed guidelines were found in the simulations to attain the 95%target for nearly all locations in the CAWS for the three test years.The developed operational guidelines have been applied since 2018 and have shown improved attainment of the DO standards throughout the CAWS while at the same time achieving similar energy use at the aeration stations on the Calumet River system,greatly lowered energy use on the Chicago River system,and greatly lowered discretionary diversion from Lake Michigan,meeting the recently enacted lower amount of allowed annual discretionary diversion.This case study indicates that emission-based real-time control developed from a well calibrated model holds potential to help many receiving water bodies achieve high attainment of water quality standards.展开更多
文摘Aim: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). Methods: A total of 582 traces of pressure-flow study from 181 men with BPH was included in the study. For each trace, maximum urinary flow rate (Qmax) and detrusor pressure at Qmax (pdet.Qmax) were, respectively, read from manually smoothed and corrected uroflow and detrusor pressure curves from the computer print-outs. Obstruction coefficient, International Continence Society (ICS) and Schaefer nomograms were used to detect urethral resistance and to diagnose obstruction. The results obtained by manual reading were compared with those from computer-based systems. Results: After manual correction, Qmax underwent a consistently significant decrease by 1.2 mL/s on average (P 〈 0.001), and had a change range of 0.5-10.4 mL/s. However, pdet.Qmax underwent inconsistently intra-individual changes after correction. The obstruction coefficient increased significantly, by an average of 0.07 (P 〈 0.05). Using the ICS nomogram, the percentage of obstruction increased from 69.8% to 73.9%, and of the non-obstruction decreased from 8.8% to 5.3% (P 〈 0.05). There were 11% of traces that changed the classifications using the ICS nomogram, and 28.9% that changed the grades for the Schaefer nomogram. Conclusion: Systematically significant differences in parameters from pres- sure-flow study between manual readings and computer recordings were demonstrated. Manual correction resulted in a consistently lower Q a higher urethral resistance, and an aggravating obstruction. Manual readings can correct considerable false diagnoses for obstruction. Retrospective quality control of pressure-flow data with com- puter-based systems is necessary.
文摘For the congestion problems in high-speed networks, a genetic based fuzzy Q-learning flow controller is proposed. Because of the uncertainties and highly time-varying, it is not easy to accurately obtain the complete information for high-speed networks. In this case, the Q-learning, which is independent of mathematic model, and prior-knowledge, has good performance. The fuzzy inference is introduced in order to facilitate generalization in large state space, and the genetic operators are used to obtain the consequent parts of fuzzy rules. Simulation results show that the proposed controller can learn to take the best action to regulate source flow with the features of high throughput and low packet loss ratio, and can avoid the occurrence of congestion effectively.
基金Sponsored by the National Natural Science Foundation of China (Grant No.51006123)the Fundamental Research Funds for the Central Universities (Grant No.14CX05028A)
文摘In order to eliminate mal-distribution and ensure the side arm to produce desirable gas quality a special distributor is proposed. The experimental distributor mainly consists of a straight through section,a gas extraction line,a liquid extraction line and a side arm branch. A gas orifice and a liquid orifice are mounted at the gas and liquid extraction line respectively to control the outlet gas quality. The diameter of the liquid orifice was set to 2. 50 mm and three gas orifices with different size( dG= 2. 65,5. 00,10. 00 mm) were tested. The experiments were carried out at an air-water two-phase flow loop. The gas superficial velocity ranged from 6. 0 to 20. 0 m /s and the liquid superficial velocity was in the range of 0. 02- 0. 18 m /s. Flow patterns such as wave flow,slug flow and annular flow were observed. The gas quality of the side arm branch was found mainly determined by the flow area ratio of the gas orifice to the liquid orifice and independent of gas and liquid superficial velocity,flow patterns and extraction flux.
文摘cytometric immunophenotyping has evolved from two-parameter quantitative measurement of peripheral blood lymphocytes to five-or more parameter qualitative evaluation of bone marrow for hematopathology.Leukemia/lymphoma immunophenotyping represent an important addition to histomorphology in the diagnosis,classification and monitoring of hematolymphoid neoplasms.The complexity of five-or more parameter analyses and the interpretation of the data rely on standardization and validation of the instrument,the reagent and the procedure.In addition,clinical flow cytometry laboratories in U.S.are required to document proficiency testing,sample preparation,method accuracy,specificity,sensitivity and precision.CLSI and the U.S.-Canadian Consensus Conference have provided recommendations,but each laboratory is responsible for validating its own qualitative and quantitative procedures.This paper introduces the procedures for quality control of all levels of the operation in a clinical flow cytometry laboratory in USA.
文摘Objective: Vein graft quality control had been traditionally done for more than 20 years with a roller-pump flow measurement (RPFM) in our institute until off-pump coronary artery bypass grafting was introduced as the standard technique of myocardial revascularization in the year 2009 in our institute. In this study, the RPFM method was compared with the Transit-time flow measurement (TTFM). Patients and Methods: From February to September 2005, 31 patients (5 females) undergoing CABG in our institute were included into the study. All the patients were operated with cardiopulmonary bypass. In those patients, 27 distal anastomoses were done with the left internal thoracic artery and 99 anastomoses were done with vein grafts. Those 99 vein graft were assessed both, with the RPFM method and TTFM method. Results: CABG could be safely performed in all cases. In all target vessels, the RPFM method overestimated bypass flow compared to the TTFM method, and simple linear regression revealed no correlation between the TTFM measurement and the RPFM measurement (r = 0.08, p = 0.21). There were two cases in which a graft problem could be detected only with TTFM method, even in our small patient cohort. Conclusion: The present study suggests that the TTFM method is clearly superior to the traditional RPFM method and we believe now that TTFM should be performed routinely in all CABG to improve patient care and quality of surgical results.
基金Project(G-0805-10156) supported by US Energy Foundation
文摘The optimum control strategy and the saving potential of all variable chiller plant under the conditions of changing building cooling load and cooling water supply temperature were investigated. Based on a simulation model of water source chiller plant established in dynamic transient simulation program (TRNSYS),the four-variable quadratic orthogonal regression experiments were carried out by taking cooling load,cooling water supply temperature,cooling water flow rate and chilled water flow rate as variables,and the fitting formulas expressing the relationships between the total energy consumption of chiller plant with the four selected parameters was obtained. With the SAS statistical software and MATHEMATICA mathematical software,the optimal chilled water flow rate and cooling water flow rate which result in the minimum total energy consumption were determined under continuously varying cooling load and cooling water supply temperature. With regard to a chiller plant serving an office building in Shanghai,the total energy consumptions under different control strategies were computed in terms of the forecasting function of cooling load and water source temperature. The results show that applying the optimal control strategy to the chiller plant can bring a saving of 23.27% in power compared with the corresponding conventional variable speed plant,indicating that the optimal control strategy can improve the energy efficiency of chiller plant.
基金Sponsored by the National Natural Science Funds of China for Young Scholar (Grant No. 61001115)the Beijing Natural Science Foundation of China(Grant No. 4102044)the Foundamental Research Funds for the Central Universities of China(Grant No.2012RC0126)
文摘In this paper, a novel flow control mechanism in cognitive packet network (CPN) based on the improved back propagation (BP) neural network is proposed, considering the flow distribution status predicted by BP neural network when packets are routed. The objective is to increase the capacity of CPN and improve the quality of service (QoS) by achieving flow balance. Besides, considering the slow convergence speed of traditional BP algorithm and the quick change of the flow status in cognitive packet network, an improved BP algorithm with dynamic learning rate is designed in order to achieve a higher convergence speed. The mechanism, which we propose, regards the predicated traffic data as an important factor when packets are routed to implement flow control. By achieving balance, the quality of network can be improved obviously. The simulation results show that the proposed mechanism provides better average time delay and packets loss ratio.
文摘In this work, the authors propose the study of a wind speed variable based on the DFAM (double fed asynchronous machine). The model of the turbine is drawn from the classical equations describing the operation of a variable wind speed. The torque generated by the turbine is applied to the DFAM directly connected on the network side and the stator via a bidirectional converter side rotor. This configuration allows velocity variations of ±30% around the synchronous speed and the converter is then sized to one third of the rated power of the machine. The DFAM is controlled by a control vector ensuring operation of the wind turbine power coefficient maximum.
基金supported by the Metropolitan Water Reclamation District of Greater Chicago(Requisition No.1449764).
文摘The Chicago Area Waterway System(CAWS)is a 133.9 km branching network of navigable waterways controlled by hydraulic structures,in which the majority of the flow is treated wastewater effluent and there are periods of substantial combined sewer overflows.The CAWS comprises a network of effluent dominated streams.More stringent dissolved oxygen(DO)standards and a reduced flow augmentation allowance have been recently applied to the CAWS.Therefore,a carefully calibrated and verified one-dimensional flow and water quality model was applied to the CAWS to determine emission-based real-time control guidelines for the operation of flow augmentation and aeration stations.The goal of these guidelines was to attain DO standards at least 95%of the time.The“optimal”guidelines were tested for representative normal,dry,and wet years.The finally proposed guidelines were found in the simulations to attain the 95%target for nearly all locations in the CAWS for the three test years.The developed operational guidelines have been applied since 2018 and have shown improved attainment of the DO standards throughout the CAWS while at the same time achieving similar energy use at the aeration stations on the Calumet River system,greatly lowered energy use on the Chicago River system,and greatly lowered discretionary diversion from Lake Michigan,meeting the recently enacted lower amount of allowed annual discretionary diversion.This case study indicates that emission-based real-time control developed from a well calibrated model holds potential to help many receiving water bodies achieve high attainment of water quality standards.