Cordyceps is a precious Chinese medicine with various pharmacological activities.In 1995,a potent immunosuppressive active sphingolipid named myriocin was isolated from the culture broth of Isaria sinclairii.FTY720,a ...Cordyceps is a precious Chinese medicine with various pharmacological activities.In 1995,a potent immunosuppressive active sphingolipid named myriocin was isolated from the culture broth of Isaria sinclairii.FTY720,a sphingolipid analogue modified from myriocin,has been developed into an important oral drug for the treatment of multiple sclerosis and organ transplantation.展开更多
文摘Cordyceps is a precious Chinese medicine with various pharmacological activities.In 1995,a potent immunosuppressive active sphingolipid named myriocin was isolated from the culture broth of Isaria sinclairii.FTY720,a sphingolipid analogue modified from myriocin,has been developed into an important oral drug for the treatment of multiple sclerosis and organ transplantation.