Purpose. To investigate the peak latency of the orbital presaccadic spike potential (SP) with horizontal eye movement in normals.Methods. Orbital SP was recorded in 28 normal subjects from 8 electrodes around the eyes...Purpose. To investigate the peak latency of the orbital presaccadic spike potential (SP) with horizontal eye movement in normals.Methods. Orbital SP was recorded in 28 normal subjects from 8 electrodes around the eyes with Pz as the reference while performing 5°, 10°, 20°, 30° and 40°horizontal saccades to visual targets. SP peak latency was measured from SP onset to SP peak on averaged data aligned on SP peak.Results. Significant main effects on SP peak latency are found for saccade size (<0. 01), saccade direction (P<0. 01) and electrode site (P<0. 05). No significant main effect on SP peak latency is found for eye (P>0. 05). SP peak latency increases with increasing saccade size from 5°to 40°. SP peak latency is longer with saccades back to center than away from center, and with abducting saccades than with adducting saccades. SP peak latency differs at the electrode sites with an order from shorter to longer as follows: inner canthus (IC); inferior orbit (IO): outer canthus (OC); superior orbit (SO).Conclusicos. The effects on the peak latency of orbital SP can be explained by the saccade dynamic property, volume conduction as well as physiologic and anatomic factors of the eyes and orbits. The peak latency of orbital SP can be used to reflect the temporal characteristics of ocular motor units controlling saccadic eye movement.展开更多
The effects of Dachengqi decoction (DCQ) and rhubarb (Rb) on the spontaneous cellularelectrical activities of guinea-pig taenia coli have been studied by intracellular microelectrode technique.DCQ and Rb both improve ...The effects of Dachengqi decoction (DCQ) and rhubarb (Rb) on the spontaneous cellularelectrical activities of guinea-pig taenia coli have been studied by intracellular microelectrode technique.DCQ and Rb both improve the depolarization of cell membrane , speed up the burst ot slow wave and spikepotentials (when the drug concentration was 1 % ,P>0. 05 , 10 % or 20 % ,P<O. 05) , which were dose de-pendent. At the same concentration the effects of Rb were more significant than those of DCQ. These re-sults suggest DCQ and Rb directly enhance the cellular electrical excitability so as to strengthen the con-traction of the colon , is one of the mechanisms of the purgative actiort of these drugs at the cellular level.The ionic basis of the effects might be that DCQ and Rb reduce the K+ conductance of the cell membranesin a resting state.展开更多
文摘Purpose. To investigate the peak latency of the orbital presaccadic spike potential (SP) with horizontal eye movement in normals.Methods. Orbital SP was recorded in 28 normal subjects from 8 electrodes around the eyes with Pz as the reference while performing 5°, 10°, 20°, 30° and 40°horizontal saccades to visual targets. SP peak latency was measured from SP onset to SP peak on averaged data aligned on SP peak.Results. Significant main effects on SP peak latency are found for saccade size (<0. 01), saccade direction (P<0. 01) and electrode site (P<0. 05). No significant main effect on SP peak latency is found for eye (P>0. 05). SP peak latency increases with increasing saccade size from 5°to 40°. SP peak latency is longer with saccades back to center than away from center, and with abducting saccades than with adducting saccades. SP peak latency differs at the electrode sites with an order from shorter to longer as follows: inner canthus (IC); inferior orbit (IO): outer canthus (OC); superior orbit (SO).Conclusicos. The effects on the peak latency of orbital SP can be explained by the saccade dynamic property, volume conduction as well as physiologic and anatomic factors of the eyes and orbits. The peak latency of orbital SP can be used to reflect the temporal characteristics of ocular motor units controlling saccadic eye movement.
文摘The effects of Dachengqi decoction (DCQ) and rhubarb (Rb) on the spontaneous cellularelectrical activities of guinea-pig taenia coli have been studied by intracellular microelectrode technique.DCQ and Rb both improve the depolarization of cell membrane , speed up the burst ot slow wave and spikepotentials (when the drug concentration was 1 % ,P>0. 05 , 10 % or 20 % ,P<O. 05) , which were dose de-pendent. At the same concentration the effects of Rb were more significant than those of DCQ. These re-sults suggest DCQ and Rb directly enhance the cellular electrical excitability so as to strengthen the con-traction of the colon , is one of the mechanisms of the purgative actiort of these drugs at the cellular level.The ionic basis of the effects might be that DCQ and Rb reduce the K+ conductance of the cell membranesin a resting state.
