Objective:To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR)in children.Methods:A total of 65 children with AR were collected from February 2...Objective:To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR)in children.Methods:A total of 65 children with AR were collected from February 2017 through to December 2018 and they were randomly divided into a combined treatment group with wrist–ankle acupuncture,pinching along the spine and western medication(combined treatment group,32 cases)and a western medication group(33 cases).In the western medication group,loratadine was prescribed for oral administration.In the combined treatment group,on the base of the medication as the western medication group,the wrist–ankle acupuncture was adopted in combination with pinching along the spine.Before and after treatment,the symptoms and physical signs were scored and the clinical effect was observed in the children of the two groups.Results:After the treatment and in the follow-up,the scores of the symptoms and physical signs in the combined treatment group were lower than those of the western medication group,indicating a statistical significance(all P<0.05).The total effective rate was 93.7%in the combined treatment group,which was higher than 63.63%in the western medication group,indicating a statistical significance(P<0.05).Conclusion:The combined treatment of wrist–ankle acupuncture combined with pinching along the spine and loratadine effectively relieves the clinical symptoms and the physical signs in AR children.The clinical effect of this combined treatment is better than the simple use of loratadine.展开更多
Objective： To investigate whether pinching spine （PS, i.e.捏脊, a traditional Chinese manipulativetherapy） is beneficial to ameliorating the depressive state （including behavioral deficit, retardative weight gaina...Objective： To investigate whether pinching spine （PS, i.e.捏脊, a traditional Chinese manipulativetherapy） is beneficial to ameliorating the depressive state （including behavioral deficit, retardative weight gainand decreased sucrose consumption） in a rat model of depression induced by chronic unpredictable stress （CUS）and to explore the candidate mechanism of action. Methods： PS was performed on rats＇ spine once daily for 1week after exposure to CUS. The open-field test, body weight measuring, and sucrose intake test were appliedon different dates： before stress （dO）, at the end of stress （d21） and after PS treatment （d28）, respectively. Thenthe rats＇ hippocampuses were performed genome-wide microarray analysis, and the expression levels of severalgenes were evaluated by real-time polymerase chain reaction （PCR）. Results： Exposure to CUS resulted indecreases of behavioral activity and sucrose consumption, which were reversed significantly after PS treatment.The expression of several genes relevant to energy metabolism, anti-oxidation, and olfactory receptor, etc., weredown-regulated, while the expression of those relevant to hemostasis, immunity-inflammation, and restrictionof activities and ingestion, etc., were up-regulated in hippocampuses of rats exposed to CUS. PS treatmentsignificantly inverted these changes. Furthermore, increase or decrease in gone expression evaluated by real-time PCR was concordant with up-regulated or down-regulated expression evaluated by microarray analysis.Conclusion： PS showed a potential antidepressant-like effect, of which the action mechanism might be due togone expression regulation in hippocampus.展开更多
文摘Objective:To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR)in children.Methods:A total of 65 children with AR were collected from February 2017 through to December 2018 and they were randomly divided into a combined treatment group with wrist–ankle acupuncture,pinching along the spine and western medication(combined treatment group,32 cases)and a western medication group(33 cases).In the western medication group,loratadine was prescribed for oral administration.In the combined treatment group,on the base of the medication as the western medication group,the wrist–ankle acupuncture was adopted in combination with pinching along the spine.Before and after treatment,the symptoms and physical signs were scored and the clinical effect was observed in the children of the two groups.Results:After the treatment and in the follow-up,the scores of the symptoms and physical signs in the combined treatment group were lower than those of the western medication group,indicating a statistical significance(all P<0.05).The total effective rate was 93.7%in the combined treatment group,which was higher than 63.63%in the western medication group,indicating a statistical significance(P<0.05).Conclusion:The combined treatment of wrist–ankle acupuncture combined with pinching along the spine and loratadine effectively relieves the clinical symptoms and the physical signs in AR children.The clinical effect of this combined treatment is better than the simple use of loratadine.
文摘Objective： To investigate whether pinching spine （PS, i.e.捏脊, a traditional Chinese manipulativetherapy） is beneficial to ameliorating the depressive state （including behavioral deficit, retardative weight gainand decreased sucrose consumption） in a rat model of depression induced by chronic unpredictable stress （CUS）and to explore the candidate mechanism of action. Methods： PS was performed on rats＇ spine once daily for 1week after exposure to CUS. The open-field test, body weight measuring, and sucrose intake test were appliedon different dates： before stress （dO）, at the end of stress （d21） and after PS treatment （d28）, respectively. Thenthe rats＇ hippocampuses were performed genome-wide microarray analysis, and the expression levels of severalgenes were evaluated by real-time polymerase chain reaction （PCR）. Results： Exposure to CUS resulted indecreases of behavioral activity and sucrose consumption, which were reversed significantly after PS treatment.The expression of several genes relevant to energy metabolism, anti-oxidation, and olfactory receptor, etc., weredown-regulated, while the expression of those relevant to hemostasis, immunity-inflammation, and restrictionof activities and ingestion, etc., were up-regulated in hippocampuses of rats exposed to CUS. PS treatmentsignificantly inverted these changes. Furthermore, increase or decrease in gone expression evaluated by real-time PCR was concordant with up-regulated or down-regulated expression evaluated by microarray analysis.Conclusion： PS showed a potential antidepressant-like effect, of which the action mechanism might be due togone expression regulation in hippocampus.
