Assessment of optic nerve and optic tract alterations in patients with orbital space-occupying lesions using probabilistic diffusion tractography

AIM: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography(PDT). METHODS: Twenty patients with orbital space-occupying lesions and 25 age-and gender-matched healthy persons were included. All patients and controls underwent routine orbital magnetic resonance imaging and diffusion tensor imaging(DTI), using a 3.0 T magnetic resonance scanner(Trio Tim Siemens). After the image data were preprocessed, each DTI parameters of the optic nerve and optic tract was obtained by PDT, including fractional anisotropy(FA), mean diffusivity(MD), axial diffusivity(AD) and radial diffusivity(RD). The asymmetry index(AI) of each parameter was calculated. Compared the parameters of the affected side optic nerve and ipsilateral optic tract with the contralateral side by paired sample t-test;compared AI of parameters of optic nerve and optic tract between the patient group and the control group by independent sample t-test. Patients were divided into threesubgroups according to the low vision grade standard of WHO, compared the FA and AI of FA between the three subgroups by single factor variance analysis. RESULTS: The affected side optic nerve presented significantly decreased FA, increased MD, AD, and RD values compared to the unaffected side(P<0.05). The AI of FA, MD, AD, and RD of optic nerve in the patients was significantly higher than that of the controls(P<0.05). The comparison results of the optic tract showed that there was no significant difference between the patient group and control group in terms of the bilateral optic tracts in patients(P>0.05). The AIs of the FA value of the optic nerve in the eyesight <0.1 subgroup was significantly higher than that in the other groups(P<0.05). CONCLUSION: FA, MD, AD, and RD of the affected side optic nerve of the orbital space-occupying lesions have significantly changed, the FA value is the most sensitive. The PDT could be a useful tool to provide valid quantitative markers of optic nerve injuries and evaluate the severity of orbital diseases, which other examinations cannot be acquired.

Recurrent orbital space-occupying lesions:a clinicopathologic study of 253 cases

Objective：To analyze the clinical features,histopathologic classification and frequencies of various types of recurrent orbital space-occupying lesions.Methods：A retrospective study was carried out in 253 consecutive patients with recurrent orbital spaceoccupying lesions treated by surgical excision in the Institute of Orbital Diseases,the General Hospital of the Armed Police Force from January 2009 to December 2010.Results：The patients included 123 males and 130 females aged 2 to 78 years（mean,36.2 years）,and the last recurrence interval after operation ranged from 1 month to 40 years（median,4.75 years）.Of all the cases,159（62.8%）,65（25.7%）,20（7.9%）,8（3.2%） and 1（0.4%） had previously experienced once,twice,three,four and six times of surgeries,respectively.Among them,29（11.5%） cases had recurred 3 times or over,and 37（14.6%） cases got recurrence in 10 or more years postoperatively.Most of the patients with local recurrence presented with various clinical manifestations,while 31（12.3%） cases were symptom-free.Two hundred and thirty-one（91.3%） cases underwent surgical removal of the recurrent orbital lesions,and another 22（8.7%） cases had to receive the exenteration of orbit.Categories of these recurrent orbital lesions after operation were as follows：lacrimal gland tumors,65（25.7%） cases;vasogenic diseases,54（21.3%） cases;neurogenic tumors,42（16.6%） cases;secondary tumors,24（9.5%） cases;orbital inflammation,21（8.3%） cases;myogenic tumors,14（5.5%） cases;fibrous and adipose tumors,12（4.7%） cases;lympho-hematopoietic tumors,7（2.8%） cases;bone or cartilage tumors,7（2.8%） cases;orbital cysts,6（2.4%） cases;and indefinitely differentiated tumor,1（0.4%） case.The 10 top histopathologic diagnoses were lacrimal gland pleomorphic adenoma,hemangiolymphangioma,lacrimal gland adenoid cystic carcinoma,meningioma,inflammatory pseudotumor,neurofibroma,sebaceous gland carcinoma,vascular malformation,rhabdomyosarcoma and hemangioma.Conclusions：The variety of recurrent orbital lesions after operation includes mainly of tumors except for vascular malformation and orbital inflammatory lesions.The lacrimal gland epithelial tumor is most prone to relapse after resection,and early and longer-term postoperative follow-up is needed.

Application of endoscopic submucosal dissection in duodenal space-occupying lesions

BACKGROUNDEndoscopic submucosal dissection (ESD) has been advocated by digestiveendoscopists because of its comparable therapeutic effect to surgery, reducedtrauma, faster recovery, and fewer complications. However, ESD for lesions of theduodenum is more challenging than those occurring at other levels of thegastrointestinal tract due to the thin intestinal wall of the duodenum, narrowintestinal space, rich peripheral blood flow, proximity to vital organs, and highrisks of critical adverse events including intraoperative and delayed bleeding andperforation. Because of the low prevalence of the disease and the high risks ofsevere adverse events, successful ESD for lesions of the duodenum has rarelybeen reported in recent years.AIM To investigate the efficacy and safety of ESD in the treatment of duodenal spaceoccupyinglesions.METHODS Clinical data of 24 cases of duodenal lesions treated by ESD at the DigestiveEndoscopy Center of the Affiliated Hospital of Qingdao University from January2016 to December 2019 were retrospectively analyzed.RESULTS All of the 24 cases from 23 patients underwent ESD treatment for duodenal spaceoccupyinglesions under general anesthesia, including 15 male and 8 femalepatients, with a mean age of 58.5 (32.0-74.0) years. There were 12 lesions (50%) inthe duodenal bulb, 9 (37.5%) in the descending part, and 3 (12.5%) in the ball descending junction. The mean diameter of the lesion was 12.75 (range, 11-22)mm. Thirteen lesions originated from the mucosa, of which 4 were low-gradeintraepithelial neoplasia, 3 were hyperplastic polyps, 2 were chronic mucositis, 2were adenomatous hyperplasia, 1 was high-grade intraepithelial neoplasia, and 1was tubular adenoma. Eleven lesions were in the submucosa, including 5neuroendocrine neoplasms, 2 cases of ectopic pancreas, 1 stromal tumor, 1leiomyoma, 1 submucosal duodenal adenoma, and 1 case of submucosal lymphfollicular hyperplasia. The intraoperative perforation rate was 20.8% (5/24),including 4 submucosal protuberant lesions and 1 depressed lesion. The meanlength of hospital stay was 5.7 (range, 3-10) d, and the average follow-up time was25.8 (range, 3.0–50.0) mo. No residual disease or recurrence was found in allpatients, and no complications, such as infection and stenosis, were found duringthe follow-up period.CONCLUSION ESD is safe and effective in the treatment of duodenal lesions;however, theendoscopists should pay more attention to the preoperative preparation,intraoperative skills, and postoperative treatment.

Investigation of lacrimal sac space-occupying lesions using color doppler ultrasound, computed tomography, and computed tomography dacryocystography

AIM:To observe the imaging features of color Doppler ultrasound(CDU)and computed tomography(CT)or computed tomography dacryocystography(CT-DCG)in different types of lacrimal sac space-occupying lesions(SOLs).METHODS:This retrospective case series study included 21 patients with lacrimal sac SOLs who underwent lacrimal sac surgery between January 2018 and March 2022.The imaging features of CDU and CT or CT-DCG in these patients were extracted from the examination cloud system.The images were observed and analyzed.RESULTS:The detection rate of lacrimal SOLs between CDU(21/21,100%)and CT or CT-DCG(20/21,95.2%)had no statistically significant difference(P=1.0).CDU could detect the blood flow signals in all SOLs except mucocele and mucopeptide concretion.Among them,polyps had characteristic imaging changes on CDU and CT-DCG.The mucoceles and mucopeptide concretions had characteristic imaging changes on CDU,which could provide more information for differential diagnosis.CONCLUSION:The morphology and internal blood flow signals of lacrimal sac SOLs can be observed using CDU.CT or CT-DCG has advantages in observing structural damage around the lacrimal sac mass.Therefore,CDU may be used as a routine examination to exclude lacrimal sac SOLs before dacryocystorhinostomy in the absence of preoperative CT or CT-DCG.

Association between the fMRI manifestations of activated brain areas and muscle strength in patients with space-occupying lesions in motor cortex

BACKGROUND ： Functional magnetic resonance imaging （fMRI） studies have disclosed the changes of the motor function in the motor cortex of ipsilateral and contralateral hemispheres of tumor, which have special significance for making the surgical planning and most greatly minimizing the postoperative functional damages. OBJECTIVE： To analyze the association between the manifestation characteristics of hand functional area and motor dysfunction using fMRI in patients with space-occupying lesions of tumor in motor cortex. DESIGN ： A case-controlled observation SETTING： Department of Radiology, Second Affiliated Hospital, Shantou University Medical College .PARTICIPANTS： Twenty-three patients （13 males and 10 females） with space-occupying lesions of central sulcus area, aged 21-53 years with a mean age of （47±1） years were selected from the Second Affiliated Hospital of Shantou University Medical College. All the patients were diagnosed by MR scanning as space-occupying lesions of motor area, and pathologically confirmed that the lesions involved central sulcus and central Iobule; Lesions occurred in left and right hemispheres in 13 and 10 cases respectively. The tumor types were astrocytoma （n =8）, metastatic tumours （n =7）, meningiomas （n =5） and oligodendroglioma （n =3）. The muscle strength was normal in 11 cases （grade 5） and obviously decreased in 12 cases （grade 2-3 in 3 cases and grade 4 in 9 cases）; muscle strengths of both upper and lower limbs were decreased in 7 cases, and only that of upper limbs was decreased in 5 cases. Informed consents were obtained from all the subjects. Meanwhile, 9 healthy physical examinees （5 males and 4 females） of 20-56 years old with an average of （34±1） years were taken as controls. All the patients and healthy subjects were right-handed. METHODS： All the enrolled subjects were examined with MR scanning and functional imaging. Twenty cases whose clinical symptoms were mild in the patient group and 9 healthy volunteers adopted simple active finger-tapping movements, and for the 3 cases whose clinical symptoms were severe in the patient group, the simple passive finger-tapping movements were used. The manifestations in the activated brain areas were analyzed in the patients with brain tumor of different muscle strength and the controls. The motor deficit and activation of contralateral primary motor cortex （M1） in simple finger-tapping movements were observed in the patient group. MAIN OUTCOME MEASURES： （1） Brain areas activated by finger-tapping movements in each group： （2） Activated volumes in hemisphere by finger-tapping movements between groups. RESULTS： The contralateral M1 area could not be activated in 1 case in the patient group,, all the other 22 patients and 9 healthy subjects were involved in the analysis of results. （1） In the control group, unilateral finger tapping movement activated the contralateral primary motor cortex （M1）, bilateral SMA and bilateral PMC. The activation volume was the largest in contralateral primary motor cortex （M1）, smaller in the SMA, and the smallest in PMC. The finger tapping movement in healthy subjects could activate contralateral primary motor cortex （M1）, bilateral SMA and bilateral PMC, which had no obvious differences from the manifestations of brain functional area activated by active finger tapping. There was no significant difference in the volume of activated functional areas between right and left hands. In the patient group, the central sulcos around the tumor in the activated M1 area displaced towards dorsal or ventral side, also extended. The distance of displacement in the functional area was determined as compared with the contralateral central sulcus, and the results suggested the M1 displacement, including that there were 10 cases with the M1 displacement larger than 10 mm in the patients with motor deficit, which were obviously more than in those without motor deficit （n =1, P 〈 0.01）, and the activated volume in contralateral M1 area was obvious smaller in the patients with motor deficit than in those without motor deficit （P 〈 0.01）. （2） The M1 activation and changes were observed in contralateral hemisphere in the patient group, and the activated volume was obviously larger than that in the control group （P 〈 0.01）. The activated volumes of M1 and PMC in ipsilateral hemisphere were obviously larger than those in the control group （P 〈 0.05）, but that of SMA had no obvious difference between the two groups （P 〉 0.05）. CONCLUSION： fMRI can be used to observe the activation of the brain motor functional areas of patient with space-occupying lesions in motor area, and evaluate the state of their motor function. The larger the distance of displacement of M1 compressed by tumor, the more obviously the muscle strength decreases in the patients.

腹腔镜脾部分切除术在脾良性占位性病变手术治疗中的疗效分析

目的评估腹腔镜脾部分切除术(laparoscopic partial splenectomy,LPS)在脾良性占位性病变手术治疗中的效果及安全性。方法分析华中科技大学同济医学院附属协和医院自2018年1月至2023年7月收治的85例脾良性占位性病变病人的临床资料,根据手术方式分为两组,25例行LPS的病人为LPS组,60例行腹腔镜全脾切除术(laparoscopic total splenectomy,LTS)的病人为LTS组。统计比较两组术前、术中、术后指标以及并发症(腹腔积液、感染、静脉血栓形成、血小板增多症等)发生率。结果两组病人均顺利完成手术。LPS组与LTS组比较,术后引流时间[(4.6±1.6)d比(5.9±1.6)d]、术后通气时间[(1.4±0.5)d比(1.9±0.8)d]、术后活动时间[(2.6±0.5)d比(3.1±0.8)d]及术后住院时间[(6.3±1.5)d比(7.8±3.1)d]均缩短,且术后第1、3天白细胞计数[(10.2±2.1)×10^(9)/L比(14.7±4.1)×10^(9)/L、(9.5±3.3)×10^(9)/L比(13.3±3.8)×10^(9)/L]及术后第1、3天血小板计数[(172.8±57.9)×10^(9)/L比(203.0±61.3)×10^(9)/L、(210.1±112.5)×10^(9)/L比(298.0±125.9)×10^(9)/L]LPS组均低于LTS组,差异均有统计学意义(均P<0.05);但两组的手术时间、术中出血量、术后引流量、红细胞计数、血红蛋白水平及白蛋白水平比较差异均无统计学意义(均P>0.05)。此外,LPS组术后并发症发生率显著低于LTS组[4.0%(1/25)比30.0%(18/60)],差异有统计学意义(χ^(2)=5.457,P<0.05)。结论LPS是一种疗效确切、安全可行的手术方式,在脾良性占位性病变的临床诊疗中具有重要价值,建议在有条件的医疗中心进行推广。

高分辨CT在脾脏占位性病变诊断及鉴别诊断中的应用价值分析

目的 探讨高分辨CT在脾脏占位性病变诊断及鉴别诊断中的应用价值。方法 采用excel表格对2021年1月—2023年10月东莞市横沥医院放射科收治的60例病例资料(疾病:脾脏占位性病变)进行统计,均实施常规CT平扫、高分辨CT检查,以病理诊断结果为金标准,分析各个方案的检出情况、诊断效能。结果 以病理诊断结果为金标准,常规CT平扫检查恶性检出率为63.64%、良性检出率为81.58%;高分辨CT检查恶性检出率为90.91%、良性检出率为97.37%。常规CT平扫检查对各疾病检出率为75.00%,高分辨CT检查对各疾病检出率为95.00%,对比差异有统计学意义(P<0.05)。高分辨CT检查敏感度(95.24%)、特异度(94.87%)、准确率(95.00%)、阳性预测值(90.91%)、阴性预测值(97.37%)与常规CT平扫检查对比差异有统计学意义(P<0.05)。以病理诊断为金标准,常规CT平扫检查Kappa指数0.612,高分辨CT检查Kappa指数0.897。结论 在脾脏占位性病变诊断中应用高分辨CT进行检查既可明确疾病类型、性质,亦可提升诊断准确率及灵敏度,为临床医师制定治疗方案提供参考,值得借鉴。

Pneumocephalus Following Combined Spinal-Epidural Anesthesia: A Case Report Analysis

Background: Combined spinal-epidural anesthesia (CSEA) is widely used in clinical anesthesia due to its rapid onset, reliable anesthetic effect, and strong controllability. Although advancements in technique have reduced the frequency and severity of common complications, reports of rare and serious complications such as pneumocephalus, remain scarce. Case Report: This article presents a case of pneumocephalus following CSEA in a middle-aged female patient undergoing surgery for an intrauterine space-occupying lesion. The patient experienced severe headache postoperatively, and imaging confirmed the presence of intracranial air. After receiving active symptomatic treatment, the patient recovered and was discharged. Conclusion: This case underscores the importance of adhering to standard anesthesia protocols and increasing awareness of rare CSEA complications, particularly the risk of pneumocephalus. Early recognition and timely management are crucial. There is a need to further enhance training and research in anesthetic procedures to improve clinical anesthesia quality and ensure patient safety.

脾脏占位性病变的诊治

目的探讨脾脏占位性病变的临床特点和诊治原则。方法回顾性分析2004年1月至2013年12月收治我院的47例肝脏占位性病变的临床资料。结果47例均行手术治疗，并经病理证实。其中良性病变26例，恶性肿瘤21例。开腹行脾脏切除术30例，腹腔镜下行脾脏切除术17例。结论脾脏占位性病变的诊断主要依靠临床表现和影像学检查，治疗以手术治疗为主的综合性治疗。

脾脏占位病变的诊断治疗

目的了解目前脾脏占位病变的疾病谱并探讨相应的诊断治疗措施。方法收集湖北省十堰市太和医院近10年来收治的脾脏占位性病变的患者资料,对其临床表现、诊断以及治疗效果进行回顾性分析。结果共收治所有脾脏占位病变患者126例,其中良性病变89例(72.4%),良性疾病中以脾囊肿,血管瘤和结核最常见,恶性肿瘤中以淋巴瘤和转移性肿瘤常见。脾切除术仍然是治疗脾脏占位病变的主要措施,对大部分病人的治疗效果理想。结论对人群的定期体检是早期发现脾脏占位病变的有效手段,脾切除术可使大多数脾脏占位患者取得满意的治疗效果。

益脾养肝方对大鼠肝癌前病变病理形态和脾脏T细胞亚群的影响

目的:观察益脾养肝方对二乙基亚硝胺(DEN)诱导的大鼠肝癌癌前病变病理形态和脾脏T细胞亚群的影响。方法:将80只大鼠随机分为空白组、模型组、益脾养肝方大、小剂量组,腹腔注射DEN制备肝癌癌前病变模型,16周后处死大鼠,检测肝功能、肝组织病理变化,脾脏组织免疫荧光染色观察CD3+、CD4+和CD8+T细胞表达情况。结果:与模型组比较,益脾养肝方小、大剂量均能显著降低ALT、AST、ALP水平,且益脾养肝方大剂量组疗效更好(P<0.01);肝组织HE、Masson染色病理切片显示,益脾养肝方大、小剂量组大鼠肝癌前病变病理形态明显改善;脾脏组织免疫荧光染色结果显示,益脾养肝方可提高CD3+、CD4+T细胞数量,降低CD8+T细胞数量。结论:益脾养肝方对大鼠肝癌前病变进展具有抑制作用,其作用机理可能是通过调节机体的免疫功能抑制肝癌形成。

超声造影技术在脾局灶性病变诊断中的应用价值

目的探讨超声造影技术在脾局灶性病变诊断中的价值。方法采用超声造影剂SonoVue对27例脾局灶性实质性病变进行超声造影检查(良性病灶18例,恶性病灶9例),实时动态地观察病灶的增强方式与增强时相。结果 (1)脾良、恶性病灶均以低增强为主。良、恶性病灶均以整体增强为主。(2)恶性病灶造影剂开始减退时间较良性病灶快,差异有统计学意义(P<0.05)。(3)常规超声与超声造影鉴别脾局灶性病变良恶性的敏感性、特异性、准确性、阳性及阴性预测值比较差异有统计学意义(P<0.05)。结论超声造影有助于提高对脾局灶性病变的诊断准确性。

脾脏占位性病变72例临床分析

目的探讨脾脏占位性病变的临床诊治措施,分析影像学对脾脏占位性病变的价值,总结有效治疗手段。方法对2008年9月～2012年10月我院收治的72例脾脏占位性病变患者的临床资料进行回顾性分析,其中良性病变50例,恶性病变22例。观察患者的临床诊断措施,并总结治疗方法。结果 72例患者的临床诊断主要包括病史、症状、体征等,影像学诊断中超声造影准确率较高,与灰阶超声比较差异有统计学意义(P<0.05);72例患者中采用手术治疗69例,保守治疗3例,患者均康复出院,无死亡病例。结论脾脏占位性病变患者使用临床综合诊断中超声造影的诊断价值较高,可以更好地对良恶性进行鉴别;对脾脏进行切除是临床治疗脾脏占位性病变的主要方法。

彩超在诊断脾脏占位性病变中的应用价值

目的探讨彩色多普勒超声对脾脏占位性病变(SSOL)的诊断价值。方法对37例经病理和临床证实的脾脏占位性病变进行二维及彩色多普勒超声分析。结果二维和彩色多普勒超声可以显示脾脏占位性病变的结构特征及血供状态,具有检出率高等特点。结论二维和彩色多普勒超声为诊断脾脏占位性病变提供了丰富的影像学资料,具有重要的临床应用价值。

二级脾蒂法腹腔镜脾切除术治疗脾脏良性病变的临床效果

目的探讨二级脾蒂法腹腔镜脾切除术在治疗脾脏良性病变中的治疗效果。方法将2011年8月31日-2015年9月14日期间在我院接受治疗的72例脾脏良性病变患者随机分为对照组（36例）和观察组（36例）,其中对照组采取内镜下切割吻合器（Endo-GAI）法治疗,观察组接受LSSP治疗,比较两组的临床疗效及并发症情况。结果两组在手术时间、术中出血量、术后留置引流管时间、术后首次排气时间及住院天数方面差异无统计学意义（P〉0.05）,在手术费用方面,观察组明显低于对照组（P〈0.05）;另外,观察组术后并发症总发生率13.89%,与对照组的36.11%比较差异有统计学意义（P〈0.05）。结论对于脾脏良性病变的治疗,LSSP与Endo-GAI法具有相似的疗效,但LSSP手术费用更低、并发症更少。

16层螺旋CT在消化系统实质器官检查技术及其在不同病变诊断中应用价值

目的研究16层螺旋计算机断层扫描(computed tomography,CT)在消化系统实质器官检查技术及其在不同病变诊断中应用价值.方法回顾性分析2012-01/2017-01在厦门大学附属第一医院接受治疗的肝脏肿瘤和肿瘤的病变患者105例,胰腺病变患者84例,脾脏病变患者111例;使用16层螺旋CT对肝脏和脾脏病变患者进行平扫加增强,对胰腺患者进行灌注扫描,分析患者的病变特征.结果C T上肝脏和脾脏病变的表征是多发或单发的低密度的病灶,边界可模糊也可清晰,增强后可不强化也可强化;胰腺癌患者Q_b、V_b低于正常者,t_(mt)、K_(ps)高于正常者,两组间t_(mt)、K_(ps)、Q_b、V_b对比差异均有统计学意义(P<0.05);胰腺炎患者的Q_b、V_b、K_(ps)与正常者对比差异有统计学意义(P<0.05),tm t与正常者对比差异无统计学意义(P>0.05);胰腺癌患者的Q_b、V_b、tm t和胰腺炎患者对比差异均有统计学意义(P<0.05).结论16层螺旋C T对肝脏病变、胰腺病变和脾脏病变患者有较高的诊断价值,值得在临床推广.

保留脾血管的胰体尾切除术对胰体尾良性病变临床疗效、并发症及生活质量的影响

目的:分析胰体尾良性病变行保留脾血管的胰体尾切除术(SPDP)的疗效、并发症及生活质量。方法:选取2015年5月-2017年5月在笔者所在医院接受胰体尾切除术治疗的128例胰体尾良性病变患者,按手术方案不同分两组,每组64例,对照组行切除脾血管SPDP术,观察组行保留血管的SPDP术,比较组间手术指标及并发症、生活质量。结果:观察组手术时间(258.54±27.31)min,比对照组长,术中出血量(161.42±30.01)ml、血小板计数(213.41±48.03)×10~9/L,均比对照组少,住院时间(13.52±2.41)d,比对照组短(P<0.01);观察组术后并发症发生率3.13%,比对照组的12.50%低(P<0.05);观察组随访1个月后的躯体功能(74.75±3.32)分、情感功能(72.03±8.99)分、精神状态(72.22±8.80)分及总体健康(76.29±8.47)分,均比对照组优(P<0.01)。结论:胰体尾良性病变行保留脾血管的胰体尾切除术有利于脾脏血供、功能的保留,预防术后并发症,改善患者生活质量,安全可行。

小儿脾脏局灶性病变的超声诊断

目的总结超声检查小儿脾脏局灶性病变的声像图特征及其临床应用价值。方法超声检查脾脏局灶性病变34例,观察病变的大小、形态、内部结构及血供情况。结果小儿脾脏局灶性病变可表现为脾实质内不均质低回声、高回声及无回声区。结论超声检查能为小儿脾脏局灶性病变的诊断,选择治疗方案提供图像依据,亦可对治疗效果作出评估。

脾占位性病变23例临床分析

目的探讨如何提高脾占位性病变的诊治水平。方法回顾性分析23例脾占位性病变的临床资料。结果本组良性病变16例,恶性病变7例。B超和CT是主要的检查方法,均行手术切除。良性病变疗效好,恶性病变预后差。结论影像检查是脾占位性病变的主要诊断手段,手术切除是主要治疗方法。

脾脏肿瘤与非肿瘤性病变的CT鉴别

目的:探讨脾脏肿瘤与非肿瘤性病变的CT表现及鉴别应用。方法:回顾性分析69例经临床确诊为脾脏病变的CT影像学资料,总结肿瘤性与非肿瘤性病灶影像特征及伴随征象,并采用卡方检验分析相关数据。结果:69例脾脏病变中,肿瘤性病变44例,边界不清者31.8%,出现包膜下积液者4.5%,出现腹膜增厚者2.3%;非肿瘤性病变25例,边界不清者56.0%,出现包膜下积液者60.0%,出现腹膜增厚者24.0%,脾脏肿瘤与非肿瘤性病变在三者的影像表现均有统计学差异(P<0.05)。结论:CT可较清晰地显示脾脏病灶,通过对病灶的边界及伴随征象的分析,有利于对脾脏肿瘤与非肿瘤性病变的鉴别。