Combining Posterolateral Lumbar Fusion and Posterior Lumber Interbody Fusion Surgery for Treating Three-Level Lumber Spondylolysis and Single-Level Spondylolisthesis: Case Report

Lumbar spondylolysis is a relatively common condition that can cause a variety of clinical manifestations related to the lumbar spine. However, multi-level lumbar spondylolysis is rare and accounts for less than 6% of lumbar spondylolysis. We report a case of three-level lumbar spondylolysis with single-level spondylolisthesis. A 47-year-old woman presented to us with low back pain for 9 years that progressively worsened and the pain was exacerbated with standing and walking. She was diagnosed with three-level lumbar spondylolysis at L3-5 and spondylolisthesis at L4. We performed posterolateral lumber fusion (PLF) and posterior lumbar interbody fusion (PLIF) surgery for her. During the same period, pain recovery and fusion rate of the patient were evaluated after surgery. The results were favorable and proved the efficacy of combining PLF and PLIF technique for treatment for three-level lumbar spondylolysis and single-level spondylolisthesis.

Surgical treatment of four segment lumbar spondylolysis:A case report

Four-level lumbar spondylolysis is extremely rare.So far,only 1 case has been reported in the literature.CASE SUMMARY A 19-year-old man presented with severe back pain irresponsive to conservative therapies for 2 years.Lumbar radiographs and two-dimensional computed tomography scan showed four segment lumbar spondylolysis on both sides of L2-L5.Lumbar magnetic resonance imaging showed normal signal in all lumbar discs.Because daily activities were severely limited,surgery was recommended for the case.The patient underwent four-level bilateral isthmic repair at L2-L5.During surgery,L2-L5 isthmi were curetted bilaterally,freshened,and then grafted with autologous iliac bone that was bridged and compressed with a pedicular screw connected to a sub-laminar hook by a short rod.The symptoms of back pain almost disappeared.He has been followed-up for 96 mo,and his symptoms have never recurred.Fusion was found in all repaired isthmi 14 mo after surgery according to evaluation of lumbar radiography and computed tomography scan.CONCLUSION We report here 1 case of four-level lumbar spondylolysis that was treated successfully with direct isthmic repair.

改进YOLOv5su模型检测桃树缩叶病

为实现自然环境下桃树缩叶病的检测,该研究提出了一种基于YOLOv5su的桃树缩叶病识别改进模型DLLYOLOv5su。首先,针对桃树缩叶病目标特征变化较大的问题,在骨干网络最后一层C3模块中加入可变形自注意力模块(deformable attention,DA),使模型更加关注目标区域,降低背景对模型的影响,提高模型在复杂背景下的拟合能力。其次在SPPF(fast spatial pyramid pooling)模块中引入LSKA(large separable kernel attention)结构,大核卷积增大了模型的感受野,使模型能够关注更多信息。最后,提出了LAWD(lightweight adaptive weighted downsampling)模块,使用轻量化的下采样结构替换卷积模块,减少计算开销。在桃树缩叶病数据集上进行试验,结果显示,DLL-YOLOv5su模型权重大小为17.6 MB,检测速度为83帧/s。识别准确率P、召回率R和平均精度均值mAP_(50)分别达到了80.7%、73.1%和80.4%,相较于原始YOLOv5su分别提高了4.2、2.4和4.3个百分点。与YOLOv3-tiny、Faster R-CNN、YOLOv7和YOLOv8相比mAP_(50)分别高出了28.5、11.8、2.1和4.1个百分点。改进模型识别精度高,误检、漏检率低,检测速度满足实时检测的要求,可以为桃树缩叶病的实时监测和预警提供参考。

小麦SUS基因家族鉴定与生物信息学分析

【目的】对小麦蔗糖合成酶(sucrose synthase,SUS)基因家族进行鉴定和生物信息学分析,为探究小麦SUS(TaSUS)基因家族的作用机制提供理论参考。【方法】采用生物信息学方法在小麦全基因组上鉴定TaSUS基因家族成员,并对其系统进化关系、染色体位置、基因结构、保守结构域、启动子顺式作用元件和基因表达模式进行分析。【结果】在小麦基因组中共鉴定到分布于14条染色体上的24个TaSUS基因,可分为3个亚组。TaSUS基因含有多个外显子,但部分基因缺失非翻译区结构。TaSUS基因家族成员启动子区域包含45种顺式作用元件,涉及植物生长发育和逆境胁迫响应。大多数TaSUS基因在小麦穗中显著表达,在叶、茎和根中的相对表达量较低。【结论】研究结果有助于了解小麦SUS基因家族的进化,为后期小麦SUS基因家族的生物功能研究奠定理论基础。

Application of a new anatomic hook-rod-pedicle screw system in young patients with lumbar spondylolysis:A pilot study

BACKGROUND The pedicle screw-laminar hook system has strong fixation and is conducive to bone graft fusion for lumbar spondylolysis.However,the current pedicle screwlaminar hook fixation system is not specifically designed for lumbar spondylolysis.AIM To investigate the clinical effects of a new anatomical hook-rod-pedicle screw system in the treatment of lumbar spondylolysis in young adults.METHODS We designed a new anatomic hook-rod-pedicle screw system for young patients with lumbar spondylolysis.The isthmus and the corresponding pedicle screw entry point were exposed through the intermuscular approach.Autogenous iliac bone graft was obtained to bridge the isthmus defect,and then the anatomic hook-rod-pedicle screw system was used to fix the isthmus in 15 young patients.RESULTS At 24 mo follow-up,the visual analogue scale score of low back pain decreased from 6.73±0.88 to 0.73±0.59,and the Oswestry disability index score decreased from 58.20±8.99 to 7.87±4.97.Computed tomography showed bilateral isthmic bone healing in 14 cases and unilateral isthmic bone healing in 1 case.Magnetic resonance imaging showed that the lumbar disc signal of diseased segment and adjacent segments had no change compared with that before surgery.The pain visual analogue scale score of the donor site was 0.20±0.41 at the last follow-up.According to the Modified Macnab score,the excellent and good rate was 100%.CONCLUSION The application of this new anatomical hook-rod-pedicle screw system to treat young patients with lumbar spondylolysis has the advantages of less trauma,a simple operation and satisfactory clinical effects.

Vibration Signal Analysis for Detecting Early-Stage Lumbar Spondylolysis Using Synthetic Bone

Bone fractures can be detected by analyzing vibration signals following bone stimulation. This method can also be applied to detect stress fractures, such as spondylolysis. The aim of this study was to investigate whether vibration signal analysis can be used to detect lumbar spondylolysis in synthetic bone. Four synthetic spondylolysis models of the fifth lumbar vertebra (Sawbones, product No. SAW1352-10: Malm&#246;, Sweden) were prepared, with the following conditions: intact, unilateral defect, and bilateral defect. Unilateral defects were created by making an incision of either half the diameter (50% incision) or the entire diameter (100% incision) in length through the pars interarticularis or pedicle. Bilateral defects were created by making an additional incision of half the diameter in length on the opposite side of the defected pars interarticularis or pedicle (50% + 100% incision). Hammering was performed five times on each spinous process of the fixed synthetic bones and vibration signals were measured using an accelerometer attached to the contralateral side of the hammer. Signals were analyzed using fast Fourier transform. The parameters analyzed included the mean power frequency, first power minimum frequency (the minimum value between the first and second peaks), spectral areas of low and high frequency bands, and the relative ratio between the spectral areas of low and high frequency bands. The relative ratio was significantly lower in the 50%, 100%, and 50% + 100% incision conditions compared to the intact condition (p < 0.01), suggesting the potential utility of vibration signal analysis in diagnosing lumbar spondylolysis.

温度对SUS410/BNi-2/Hastelloy X钎焊接头界面组织及力学性能的影响

目的针对汽封部件的高质量制造需求,系统研究了温度对SUS410/BNi-2/Hastelloy X钎焊接头微观组织及力学性能的影响。方法将以SUS410/BNi-2/Hastelloy X搭接结构装配的试样放入真空炉中在不同温度(1060~1140℃)下进行钎焊连接,利用SEM和EDS等手段分析钎料与母材之间的相互作用,测试接头的力学性能并分析接头断裂行为,研究温度对接头界面组织演化和力学性能的影响。结果钎缝主要由Ni(s,s)与Cr-B相组成,B元素扩散进入两侧母材,在晶界处聚集形成硼化物相。随着钎焊温度的升高,钎缝中富Cr的硼化物和浅灰色Ni(s,s)相消失,形成均匀的Ni(s,s)组织,两侧母材中B元素扩散深度增加。随着钎焊温度不断升高,钎焊接头的抗剪强度逐渐上升,上升到某一强度后,温度继续升高,但强度反而下降,断裂位置由钎缝中心先转移至Hastelloy X基体,随着温度继续升高,断裂位置又转移至SUS410扩散区。断裂形式由脆性断裂转变为韧性断裂。结论采用BNi-2黏带钎料实现了SUS410与Hastelloy X合金的可靠连接,接头典型界面组织为SUS410/扩散区((Fe,Cr)+(Fe,Cr)-B)/钎缝区(Ni(s,s)+Cr-B+β_(1)-phases)/扩散区(γ-phase+(Cr,Ni)-B+(Cr,Ni,Mo)-B)/Hastelloy X;钎焊接头的最大抗剪强度为235.6 MPa(1100℃)。

Return to sports activity by athletes after treatment of spondylolysis

AIM:To clarify the efficacy of conservative and surgical treatment of spondylolysis in athletes.METHODS:PubMed was used to perform a search of the literature for studies published during the period from 1990 to 2009 that reported data on the outcome of conservative or surgical treatment of spondylolysis in athletes.The articles were examined for data on the percentage of athletes who returned to sports activities and the interval between the start of treatment and their return.RESULTS:Five studies were identified.Two studies were concerned with conservative treatment and the other three with surgical treatment(wire fixation or screw fixation with bone graft).The percentages of athletes who returned to sports activities ranged from 80.0%to 89.3%and from 81.9%to 100%,respectively,and the intervals until their return ranged from 5.4 to 5.5 mo and from 7 to 12 mo,respectively.CONCLUSION:The percentages of athletes who returned to sports activities after conservative and surgical treatment appeared to be satisfactory,but the

Pulsed current-assisted twelve-roll precision rolling deformation of SUS304 ultra-thin strips with exceptional mechanical properties

Innovative pulsed current-assisted multi-pass rolling tests were conducted on a 12-roll mill during the rolling deformation processing of SUS304 ultra-thin strips.The results show that in the first rolling pass,the rolling reduction rate of a conventionally rolled sample(at room temperature)is 33.8%,which can be increased to 41.5%by pulsed current-assisted rolling,enabling the formation of an ultra-thin strip with a size of 67.3μm in only one rolling pass.After three passes of pulsed current-assisted rolling,the thickness of the ultra-thin strip can be further reduced to 51.7μm.To clearly compare the effects of a pulsed current on the microstructure and mechanical response of the ultra-thin strip,ultra-thin strips with nearly the same thickness reduction were analyzed.It was found that pulsed current can reduce the degree of work-hardening of the rolled samples by promoting dislocation detachment,reducing the density of stacking faults,inhibiting martensitic phase transformation,and shortening the total length of grain boundaries.As a result,the ductility of ultra-thin strips can be effectively restored to approximately 16.3%while maintaining a high tensile strength of 1118 MPa.Therefore,pulsed current-assisted rolling deformation shows great potential for the formation of ultra-thin strips with a combination of high strength and ductility.

SU电器产品的差异化营销策略研究

文章围绕SU电器平台展开差异化营销策略优化探讨,通过深入分析SU电器平台的市场定位和发展现状,提出了针对性优化建议。SU电器应充分利用自身资源优势,通过提升产品品质和服务水平,加强品牌宣传和推广,探索多元化的渠道拓展方式,以形成规模效应,提升市场竞争力。同时,SU电器还应注重市场变化和消费者需求的变化,持续优化营销策略,实现可持续发展。

SUS321不锈钢表面Cr/CrN涂层的制备与抗氧化及耐腐蚀研究

采用磁控溅射技术,在SUS321不锈钢表面制备Cr/Cr N涂层,利用扫描电子显微镜(SEM)、X射线衍射仪(XRD)及分析天平等分别表征样品高温氧化及酸性盐雾腐蚀实验后的微结构及增重。结果表明,当磁控溅射气体分压比为P_(Ar)/P_(N_(2))=3∶1的涂层样品抗氧化性能及耐腐蚀性能最佳。在此基础上通过循环沉积制备了多层Cr/CrN涂层,6周期涂层样品在600℃氧化200 h后的单位面积增重为3.599 g/m^(2),表面氧化膜致密,没有出现剥落现象;6周期的涂层样品在酸性盐雾环境中能够保持480 h表面无变化,在放置500 h后边缘部位才开始出现轻微锈迹。固定磁控溅射气体分压比为P_(Ar)/P_(N_(2))=3∶1时,制备的6周期Cr/CrN多层膜涂层具有最佳的抗氧化及耐酸性盐雾腐蚀性能。

从小米SU7爆火看雷军十八般营销武艺

近日,小米汽车SU7重磅发布,根据小米汽车官方信息,4分钟内完成大定10000辆,27分钟实现50000辆,24小时达88898辆。小米汽车旗开得胜,它像鲶鱼一样,无形中搅动了新能源汽车市场。雷军的营销能力有目共睹,这一仗让他再创辉煌。小米汽车面世用到了18个经典营销原理,其具体做法对营销人员具有借鉴意义。

SuperPATH入路与MDAA入路在老年患者髋关节置换术中的应用价值

【目的】探讨改良直接前方入路(MDAA)与SuperPATH入路在老年患者髋关节置换术中的应用价值。【方法】选取2020年7月至2023年7月在河南省洛阳正骨医院(河南省骨科医院)行髋关节置换术的104例老年患者,根据治疗方法不同分为观察组(采用SuperPATH入路髋关节置换术,n=54)和对照组(采用MDAA入路髋关节置换术,n=50)。比较两组手术相关指标、Harris髋关节功能评分、患侧髋臼杯前倾角和外展角、疼痛程度评分、并发症发生率及白细胞介素-6(IL-6)、去甲肾上腺素(NE)、醛固酮(ALD)水平。【结果】观察组患者手术时间及术后首次下床活动时间均短于对照组(P<0.05),术中切口长度短于对照组(P<0.05)。术后1周、术后1个月,观察组髋关节功能评分高于对照组(P<0.05)。术后1个月,观察组患侧髋臼杯外展角小于对照组(P<0.05)。术后1周,观察组疼痛程度评分低于对照组(P<0.05)。术后24 h,两组IL-6、NE、ALD均升高,但观察组低于对照组(P<0.05)。两组股外侧皮神经损伤发生率比较,差异无统计学意义(P>0.05)。【结论】MDAA入路与SuperPATH入路应用于老年患者髋关节置换术中,可促进患者髋关节功能恢复,安全性均良好,但SuperPATH入路术式,可缩短术中切口长度,缩小术后患侧髋臼外展角,提升术后髋关节功能,减轻患者术后疼痛。

厚壁SUS321焊接工艺研究

SUS321是含有稳定化元素Ti的奥氏体型不锈钢,在锅炉和石化容器产品中有着广泛应用。厚壁SUS321在应用中较为少见,其埋弧焊焊接工艺的应用及厚壁条件下的试板成形需要经过验证,其各项性能也需得到保证。通过焊接工艺试验,对厚壁SUS321不锈钢试板进行工艺性检验,并对试板进行力学性能、微观组织等检验。最终证明用于厚壁SUS321国产埋弧焊焊丝工艺性良好,各项性能均满足使用要求。

SUS430LX冷弯裂纹缺陷分析与控制

冷弯开裂是一种材料加工性能类缺陷,针对SUS430LX冷弯开裂缺陷,采用扫描电镜和能谱分析检测了冷弯部位及基体析出相情况。从检测分析结果来看,析出相是引起冷弯开裂的主要原因。围绕断面不同位置析出相的特点,对影响析出相尺寸、数量及类型的主要因素进行了讨论,并提出优化方向。

Study on clinical effects of pedicle screw combined with immobilized implantation bone by wirerope and hallow compression screw immobilization in treating spondylolysis of lumbar vertebra of multiple segments of adults

Objective:To observe clinical effects of pedicle screw fixation combined with cable wires and bone graft and cannulated compression screws on adult multi-segment lumbar spondylolysis.Methods:70 cases of patients with multi-segment lumbar spondylolysis were selected in our hospital.According to different surgical schemes,these patients were divided into the observation group(35 cases)and the control group(35 cases).The observation group received pedicle screw fixation combined with cable wires and bone graft and the control group received cannulated compression screw fixation.Macnab criteria were adopted to implement a therapeutic evaluation of two groups of patients to make an observation and comparison of the excellent and good rate of surgery and a series of indicators including perioperative clinical effects,intraoperative blood loss,duration of surgery,hospital length of stay(HLOS),visual analogue scale(VAS),Oswestry disability index and Japanese Orthopaedic Association(JOA)score.Results:The excellent and good rate of the observation group was 97.14%,and that of the control group was 82.86%,the difference between two groups was statistically significant(χ^(2)=6.248,p=0.012).The differences in intraoperative blood loss,duration of surgery and HLOS between two groups were statistically significant(t=-4.55,t=-4.55,t=-4.55;p<0.05).Oswestry index,VAS score and JOA score of the observation group were(2.4±0.9),(28.5±6.4)and(27.1±3.1)respectively,and these of the control group were(3.5±1.2),(37.1±7.8)and(21.3±2.7)respectively,the differences between two groups were statistically significant(t=4.338,t=5.043,t=8.347,p<0.05).Conclusions:Pedicle screw combined with immobilized implantation bone by wirerope has an excellent clinical effect on the treatment of adult multi-segment lumbar spondylolysis,and it has a series of advantages such as fast postoperative recovery,small surgical trauma and so on.In addition,this technique can also restore the stability of spinal segments and relieve pains to a greater degree.

日本SUS630不锈钢洁净度分析

本文对日本某钢厂模铸生产的两种传感器用SUS630不锈钢进行了洁净度分析。结果表明:SUS630不锈钢棒材中夹杂物类型主要为氧化物O-Al-Ca-Mg,少部分夹杂物为O-Al-Ca-Mg-S;SUS630不锈钢板材中夹杂物类型主要为氧化物O-Mg-Al-Si-Mn,少部分夹杂物为O-Mn-Al-Si-Ti、O-Mn-Si-Al-Ca;它们的夹杂物形貌均为球形或近球形。棒材、板材中夹杂物密度、平均等效直径、面积占比分别为:26/mm^(2)、3.1μm、0.024%,以及:29/mm^(2)、2.3μm、0.013%;棒材的夹杂物评级结果为细系B1.0、细系D1.0,板材的夹杂物评级结果为细系B0.5、细系D1.0,两材料的洁净度整体控制水平较高;此外,钢中还存在超细微Nb(C,N)夹杂物。

SUS441不锈钢/Al金属间化合物微叠层复合板的界面结构与力学性能

采用“表面预处理—交替层叠—热轧复合—热处理”的工艺流程制备了SUS441不锈钢/Al金属间化合物微叠层复合板。利用光学显微镜、X射线衍射仪、扫描电子显微镜等检测与表征方法研究了热处理温度对复合板界面形貌、微观组织、物相组成、维氏硬度、拉伸性能的影响。结果表明:复合板界面结合良好;热处理后,固–液反应界面氧化严重,易导致界面分层而开裂;固–固、固–半固、固–液热处理后,金属间化合物层由均匀层和两相层组成,均匀层的物相组成为Fe_(2)A_(15),两相层的物相组成为Fe_(4)Al_(13)和Al_(13)Cr_(2),且两相层具有韧性特征,固–半固反应所得到的复合板的综合力学性能最佳。

Calculation of the Standard Model Parameters and Particles Based on a SU(4) Preon Model

This paper describes an extension and a new foundation of the Standard Model of particle physics based on a SU(4)-force called hyper-color, and on preon subparticles. The hyper-color force is a generalization of the SU(2)-based weak interaction and the SU(1)-based right-chiral self-interaction, in which the W-and the Z-bosons are Yukawa residual-field-carriers of the hyper-color force, in the same sense as the pions are the residual-field-carriers of the color SU(3) interaction. Using the method of numerical minimization of the SU(4)-action based on this model, the masses and the inner structure of leptons, quarks and weak bosons are calculated: the mass results are very close to the experimental values. We calculate also precisely the value of the Cabibbo angle, so the mixing matrices of the Standard model, CKM matrix for quarks and PMNS matrix for neutrinos can also be calculated. In total, we reduce the 29 parameters of the Standard Model to a total of 7 parameters.

SUS430/Q355/SUS430不锈钢-碳钢复合板非真空试制开发

利用松下YC-400TX电焊机、Φ450 mm热轧实验机组等设备试制开发SUS430/Q355/SUS430不锈钢-碳钢非真空复合钢板,并对其进行了宏观低倍、微观金相组织、复合处元素扩散以及力学性能等检测分析。结果表明:SUS430/Q355/SUS430非真空热轧复合钢板结合强度好,生产工艺合理,并对试制过程易出现的问题提出了改进措施。