Objective:To explore the situation of patients and the compare the effect between two methods,which are preserving spontaneous breathing without intubation and endotracheal intubation with one lung ventilation in the ...Objective:To explore the situation of patients and the compare the effect between two methods,which are preserving spontaneous breathing without intubation and endotracheal intubation with one lung ventilation in the single-hole thoracoscopic bulla suture.Method:42 patients who received single-hole thoracoscopic pulmonary bullae suture in our hospital from January 2020 to December 2021 were selected as the study subjects,including 19 patients who underwent endotracheal intubation and one lung ventilation as the control group and 23 patients who underwent single-hole thoracoscopic pulmonary bullae suture without intubation as the study group.The relevant indexes,postoperative general conditions,complications and pneumothorax recurrence of the two groups were analyzed and observed.Results:In the control group,the scores of anesthesia time(points),resuscitation time(points),surgical visual field score(points),surgical time(points),and surgical bleeding volume(points)were 20.8±4.6,19.9±7.9,1.7±0.5,44.9±7.9,and 11.4±2.4 respectively.In the study group,the scores of anesthesia time(points),resuscitation time(points),surgical visual field score(points),surgical time(points),and scores of surgical bleeding(points)were 17.9±4.3,15.4±3.4,1.9±0.4,48.4±7.1,10.9±2.2,respectively.There was no statistical difference in surgical visual field score,surgical time and surgical bleeding whereas there was a statistical difference between anesthesia time and resuscitation time.In the control group after operation,VAS score at 6 hours after operation,SaO_(2)(%)after operation,PaCO_(2)(mmHg)after operation,drainage volume(ML)after operation,feeding time(H)after operation,retention time of thoracic tube after operation(H),WBC(109)on the first day after operation,hospitalization time(d),and total hospitalization cost(RMB 1000)were 2.1±0.7,98.2±1.4,42.4±4.9,139.1±23.1,6.9±1.6,37.1±5.4,7.9±2.1,6.6±1.3,and 2.6±0.3 respectively.As for the study group,the VAS score at 6 hours after operation,SaO_(2)(%)after operation,PaCO_(2)(mmHg)after operation,drainage volume(ML)after operation,feeding time(H)after operation,retention time of thoracic tube after operation(H),WBC(109)on the first day after operation,hospitalization time(d),and total hospitalization cost(RMB 1000)were 1.9±0.4,97.9±1.2,42.8±5.1,151.8±21.9,4.3±1.4,15.3±2.6,5.2±2.3,4.2±1.2,and 1.8±0.4 respectively.Among them,there were no significant differences in visual analog scale(VAS)score at 6 hours after operation,SaO_(2) after operation and PaCO_(2) after operation between the two groups,but there were significant differences in other factors.The complication rate of the control group was 36.84%,which was significantly higher than that of the study group(4.35%),with statistical difference.The recurrence rate of the control group was 21.05%,which was not significantly different from that of the study group(4.35%).Conclusion:The single-hole thoracoscopic bullae suture without intubation can reduce the anesthesia time and resuscitation time of patients,reduce the hospitalization cost of patients,reduce the treatment burden,shorten the first feeding time,and reduce the complication rate of patients.Therefore,it is worthy of clinical promotion.展开更多
Successful weaning from ventilator play a critical role in improving the prognosis of patients who are treated in the intensive care unit(ICU).Several spontaneous breath trials(SBTs)have been developed to evaluate the...Successful weaning from ventilator play a critical role in improving the prognosis of patients who are treated in the intensive care unit(ICU).Several spontaneous breath trials(SBTs)have been developed to evaluate the ability of an individual patient to remain spontaneous breathing after disconnecting mechanical ventilation.However,it remains unclear which SBT techniques should be preferentially taken into consideration for critically ill patients receiving ventilator.We performed this network meta-analysis to investigate the comparative efficacy of all common SBTs and then found that automatic tube compensation(ATC)was better than others in increasing initial SBTsuccess rate and successful weaning rate.Therefore,ATC should be optimally considered to assess the ability of liberating ventilator in critical ill.展开更多
Objective To investigate the effects of continuous tracheal gas insufflation (CTGI) combined with biphasic intermittent positive airway pressure (BIPAP) ventilation on dogs with spontaneous breathing. Methods Eight ...Objective To investigate the effects of continuous tracheal gas insufflation (CTGI) combined with biphasic intermittent positive airway pressure (BIPAP) ventilation on dogs with spontaneous breathing. Methods Eight canine models with oleic acid induced lung injury and spontaneous breathing were ventilated in a random order by Evita 2 (Drager Inc., Germany) in modes of BIPAP (BIPAP group) and BIPAP with CTGI flow rate of 3, 6 and 9?L/min (T3, T6 and T9 groups), respectively. The setting parameters of BIPAP were fiction of inspired oxygen 60%, inspiratory to expiratory ratio 1∶1, respiratory rate 20 and positive end expiratory pressure 5?cm?H2O. Arterial and mixed venous blood gas, lung mechanics, systemic and pulmonary hemodynamics status were monitored at the same level of PaCO2 obtained by adjusting peak inspiratory pressure of BIPAP. Results Peak inspiratory pressure in the T6 group (14±4?cm?H2O) and in the T9 group (11±3?cm?H2O) were significantly lower than that of BIPAP (20±5?cm?H2O, P<0.01), but there was no significant difference among the T3, T6 and T9 groups or between the T3 and BIPAP groups. PaO2, mean artery blood pressure, mean pulmonary artery pressure, pulmonary artery wedge pressure, cardiac ouput, oxygen delivery and oxygen consumption all remained unchanged in four different conditions.Conclusions Using BIPAP combined with CTGI does not cause asynchrony between ventilator and spontaneous breathing, but significantly decreases airway pressure with no influence on hemodynamics and oxygenation. Therefore, BIPAP with CTGI may be a useful support technique, especially in cases where the airway pressure should be limited.展开更多
目的探讨有创机械通气患者在通过自主呼吸试验后拔管失败的危险因素。方法对2006年5月～2007年10月入住中山医院急诊ICU并接受有创机械通气48 h以上的患者进行前瞻性调查,采用7 cm H2O的压力支持模式持续30 min进行自主呼吸试验,记录自...目的探讨有创机械通气患者在通过自主呼吸试验后拔管失败的危险因素。方法对2006年5月～2007年10月入住中山医院急诊ICU并接受有创机械通气48 h以上的患者进行前瞻性调查,采用7 cm H2O的压力支持模式持续30 min进行自主呼吸试验,记录自主呼吸试验前后的临床资料,按照拔管结局将患者分为拔管成功组和拔管失败组。结果58例患者通过自主呼吸试验后拔管,其中47例(81%)拔管成功,11例(19%)拔管失败进行再插管。单因素分析显示:老年人[拔管失败组年龄(78.1±7.9)岁,拔管成功组年龄(67.4±15.1)岁,P<0.05]、较高的浅快呼吸指数[拔管失败组(83±12)次.min-1.L-1,拔管成功组(68±19)次.min-1.L-1,P<0.05]以及较多的气道分泌物(拔管失败组54.5%,拔管成功组21.3%,P<0.05)与拔管失败有关。结论有创机械通气患者在通过自主呼吸试验后,年龄、浅快呼吸指数及气道分泌物量是预测拔管失败的有效指标。展开更多
文摘Objective:To explore the situation of patients and the compare the effect between two methods,which are preserving spontaneous breathing without intubation and endotracheal intubation with one lung ventilation in the single-hole thoracoscopic bulla suture.Method:42 patients who received single-hole thoracoscopic pulmonary bullae suture in our hospital from January 2020 to December 2021 were selected as the study subjects,including 19 patients who underwent endotracheal intubation and one lung ventilation as the control group and 23 patients who underwent single-hole thoracoscopic pulmonary bullae suture without intubation as the study group.The relevant indexes,postoperative general conditions,complications and pneumothorax recurrence of the two groups were analyzed and observed.Results:In the control group,the scores of anesthesia time(points),resuscitation time(points),surgical visual field score(points),surgical time(points),and surgical bleeding volume(points)were 20.8±4.6,19.9±7.9,1.7±0.5,44.9±7.9,and 11.4±2.4 respectively.In the study group,the scores of anesthesia time(points),resuscitation time(points),surgical visual field score(points),surgical time(points),and scores of surgical bleeding(points)were 17.9±4.3,15.4±3.4,1.9±0.4,48.4±7.1,10.9±2.2,respectively.There was no statistical difference in surgical visual field score,surgical time and surgical bleeding whereas there was a statistical difference between anesthesia time and resuscitation time.In the control group after operation,VAS score at 6 hours after operation,SaO_(2)(%)after operation,PaCO_(2)(mmHg)after operation,drainage volume(ML)after operation,feeding time(H)after operation,retention time of thoracic tube after operation(H),WBC(109)on the first day after operation,hospitalization time(d),and total hospitalization cost(RMB 1000)were 2.1±0.7,98.2±1.4,42.4±4.9,139.1±23.1,6.9±1.6,37.1±5.4,7.9±2.1,6.6±1.3,and 2.6±0.3 respectively.As for the study group,the VAS score at 6 hours after operation,SaO_(2)(%)after operation,PaCO_(2)(mmHg)after operation,drainage volume(ML)after operation,feeding time(H)after operation,retention time of thoracic tube after operation(H),WBC(109)on the first day after operation,hospitalization time(d),and total hospitalization cost(RMB 1000)were 1.9±0.4,97.9±1.2,42.8±5.1,151.8±21.9,4.3±1.4,15.3±2.6,5.2±2.3,4.2±1.2,and 1.8±0.4 respectively.Among them,there were no significant differences in visual analog scale(VAS)score at 6 hours after operation,SaO_(2) after operation and PaCO_(2) after operation between the two groups,but there were significant differences in other factors.The complication rate of the control group was 36.84%,which was significantly higher than that of the study group(4.35%),with statistical difference.The recurrence rate of the control group was 21.05%,which was not significantly different from that of the study group(4.35%).Conclusion:The single-hole thoracoscopic bullae suture without intubation can reduce the anesthesia time and resuscitation time of patients,reduce the hospitalization cost of patients,reduce the treatment burden,shorten the first feeding time,and reduce the complication rate of patients.Therefore,it is worthy of clinical promotion.
文摘Successful weaning from ventilator play a critical role in improving the prognosis of patients who are treated in the intensive care unit(ICU).Several spontaneous breath trials(SBTs)have been developed to evaluate the ability of an individual patient to remain spontaneous breathing after disconnecting mechanical ventilation.However,it remains unclear which SBT techniques should be preferentially taken into consideration for critically ill patients receiving ventilator.We performed this network meta-analysis to investigate the comparative efficacy of all common SBTs and then found that automatic tube compensation(ATC)was better than others in increasing initial SBTsuccess rate and successful weaning rate.Therefore,ATC should be optimally considered to assess the ability of liberating ventilator in critical ill.
文摘Objective To investigate the effects of continuous tracheal gas insufflation (CTGI) combined with biphasic intermittent positive airway pressure (BIPAP) ventilation on dogs with spontaneous breathing. Methods Eight canine models with oleic acid induced lung injury and spontaneous breathing were ventilated in a random order by Evita 2 (Drager Inc., Germany) in modes of BIPAP (BIPAP group) and BIPAP with CTGI flow rate of 3, 6 and 9?L/min (T3, T6 and T9 groups), respectively. The setting parameters of BIPAP were fiction of inspired oxygen 60%, inspiratory to expiratory ratio 1∶1, respiratory rate 20 and positive end expiratory pressure 5?cm?H2O. Arterial and mixed venous blood gas, lung mechanics, systemic and pulmonary hemodynamics status were monitored at the same level of PaCO2 obtained by adjusting peak inspiratory pressure of BIPAP. Results Peak inspiratory pressure in the T6 group (14±4?cm?H2O) and in the T9 group (11±3?cm?H2O) were significantly lower than that of BIPAP (20±5?cm?H2O, P<0.01), but there was no significant difference among the T3, T6 and T9 groups or between the T3 and BIPAP groups. PaO2, mean artery blood pressure, mean pulmonary artery pressure, pulmonary artery wedge pressure, cardiac ouput, oxygen delivery and oxygen consumption all remained unchanged in four different conditions.Conclusions Using BIPAP combined with CTGI does not cause asynchrony between ventilator and spontaneous breathing, but significantly decreases airway pressure with no influence on hemodynamics and oxygenation. Therefore, BIPAP with CTGI may be a useful support technique, especially in cases where the airway pressure should be limited.
文摘目的探讨有创机械通气患者在通过自主呼吸试验后拔管失败的危险因素。方法对2006年5月～2007年10月入住中山医院急诊ICU并接受有创机械通气48 h以上的患者进行前瞻性调查,采用7 cm H2O的压力支持模式持续30 min进行自主呼吸试验,记录自主呼吸试验前后的临床资料,按照拔管结局将患者分为拔管成功组和拔管失败组。结果58例患者通过自主呼吸试验后拔管,其中47例(81%)拔管成功,11例(19%)拔管失败进行再插管。单因素分析显示:老年人[拔管失败组年龄(78.1±7.9)岁,拔管成功组年龄(67.4±15.1)岁,P<0.05]、较高的浅快呼吸指数[拔管失败组(83±12)次.min-1.L-1,拔管成功组(68±19)次.min-1.L-1,P<0.05]以及较多的气道分泌物(拔管失败组54.5%,拔管成功组21.3%,P<0.05)与拔管失败有关。结论有创机械通气患者在通过自主呼吸试验后,年龄、浅快呼吸指数及气道分泌物量是预测拔管失败的有效指标。
文摘目的:观察改良自主呼吸实验(spontaneous breathing trail,SBT)在老年慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者撤机过程中的效果。方法:选择我科从2013年1月至2014年11月需要有创机械通气的慢性阻塞性肺疾病急性加重期(AECOPD)患者,随机分为2 h SBT组(常规SBT组)和6 h SBT组(改良SBT组),比较两组患者的性别、年龄、SBT前急性生理与慢性健康评分(acute physiology and chronic health evaluationⅡ,APACHEⅡ)、通气时间、氧合指数、呼吸浅快指数(RSBI)和最大吸气负压(MIP)、SBT和撤机结局、ICU病死率和ICU停留时间。结果:共入组41例患者,常规SBT组20例,改良SBT组21例。两组间性别、年龄、SBT前APACHEⅡ评分、通气时间、氧合指数、RSBI和MIP比较差异无显著性(P>0.05)。常规SBT组的患者SBT成功率(90.0%)显著高于改良SBT组(57.1%)(P=0.018)。通过SBT的患者中,常规SBT组患者的撤机成功率(72.2%)则显著低于改良SBT组(100.0%)(P=0.046)。两组患者的总体ICU病死率和ICU停留时间比较差异无显著性(P>0.05)。结论 :改良的SBT法对老年COPD患者可以更好地预测撤机成功率,并且不增加患者的ICU病死率和ICU停留时间。
