Number and quantities of reference standards (RS) needed for the quality control of drugs are increasing, bringing great pressure to the calibration and using company. This manuscript summarized the four generations f...Number and quantities of reference standards (RS) needed for the quality control of drugs are increasing, bringing great pressure to the calibration and using company. This manuscript summarized the four generations for the development of RS including physical RS, paper atlas, substitute RS and electronic databases. The advantages and disadvantages of each generation were summarized. The concept of digital RS (DRS) was proposed based on this, and summed up the definition, advantages, and technical architecture of DRS. The 10 characteristics of five aspects of the DRS were discussed including digital, multi-dimension, big data, cloud computing, internet, internet of things, sharing, multi-terminal, intelligence, and compliance certification. Then, the necessity of its formation and application in the medicine holistic quality control of internet plus era was discussed in this manuscript.展开更多
In multisignature schemes signers can sign either in a linear order or not in any specified order, but neither of them is adequate in some scenarios where require mixture using of orderless and ordered multisignature....In multisignature schemes signers can sign either in a linear order or not in any specified order, but neither of them is adequate in some scenarios where require mixture using of orderless and ordered multisignature. Most order-specified multisignatures specified the orders as linear ones. In this paper, we proposed an order-specified multisignature scheme based on DSA secure against active insider attack. To our knowledge, it is the first order-specified multisignature scheme based on DSA signature scheme, in which signers can sign in flexible order represented by series-parallel graphs. In the multisignature scheme verification to both signers and signing order are available. The security of the scheme is proved by reduce to an identification scheme that is proved have some concrete security. The running time of verifying a signature is comparable to previous schemes while the running time of multisignature generation and the space needed is less than those schemes.展开更多
The concept of batch verifying multiple digital signatures is to find a method by which multiple digital signatures can be verified simultaneously in a lower time complexity than separately verifying all the signature...The concept of batch verifying multiple digital signatures is to find a method by which multiple digital signatures can be verified simultaneously in a lower time complexity than separately verifying all the signatures. In this article, we analyze the complexity of the batch verifying schemes defined by Li, Hwang and Chen in 2010, and propose a new batch verifying multiple digital signature scheme, in two variants： one for RSA - by completing the Harn＇s schema with an identifying illegal signatures algorithm, and the other adapted for a modified Elliptic Curve Digital Siggnature Algorithm protocol.展开更多
文摘Number and quantities of reference standards (RS) needed for the quality control of drugs are increasing, bringing great pressure to the calibration and using company. This manuscript summarized the four generations for the development of RS including physical RS, paper atlas, substitute RS and electronic databases. The advantages and disadvantages of each generation were summarized. The concept of digital RS (DRS) was proposed based on this, and summed up the definition, advantages, and technical architecture of DRS. The 10 characteristics of five aspects of the DRS were discussed including digital, multi-dimension, big data, cloud computing, internet, internet of things, sharing, multi-terminal, intelligence, and compliance certification. Then, the necessity of its formation and application in the medicine holistic quality control of internet plus era was discussed in this manuscript.
基金Supported by the National Natural Science Foundation ofChina (60403027)
文摘In multisignature schemes signers can sign either in a linear order or not in any specified order, but neither of them is adequate in some scenarios where require mixture using of orderless and ordered multisignature. Most order-specified multisignatures specified the orders as linear ones. In this paper, we proposed an order-specified multisignature scheme based on DSA secure against active insider attack. To our knowledge, it is the first order-specified multisignature scheme based on DSA signature scheme, in which signers can sign in flexible order represented by series-parallel graphs. In the multisignature scheme verification to both signers and signing order are available. The security of the scheme is proved by reduce to an identification scheme that is proved have some concrete security. The running time of verifying a signature is comparable to previous schemes while the running time of multisignature generation and the space needed is less than those schemes.
文摘The concept of batch verifying multiple digital signatures is to find a method by which multiple digital signatures can be verified simultaneously in a lower time complexity than separately verifying all the signatures. In this article, we analyze the complexity of the batch verifying schemes defined by Li, Hwang and Chen in 2010, and propose a new batch verifying multiple digital signature scheme, in two variants： one for RSA - by completing the Harn＇s schema with an identifying illegal signatures algorithm, and the other adapted for a modified Elliptic Curve Digital Siggnature Algorithm protocol.
