BACKGROUND Helicobacter pylori(H.pylori)infection is predominantly acquired in childhood.When indicated,the most accepted treatment for H.pylori eradication in this age group is first-line triple therapy.However,the i...BACKGROUND Helicobacter pylori(H.pylori)infection is predominantly acquired in childhood.When indicated,the most accepted treatment for H.pylori eradication in this age group is first-line triple therapy.However,the increasing resistance to clarithromycin and nitroimidazoles has been associated with treatment failure,and thus,alternative treatment regimens have been proposed.AIM To perform a systematic review of randomized controlled trials on treatment regimens for H.pylori infection in children.METHODS We surveyed relevant articles published in English from 2010 to April 2020 in the PubMed and MEDLINE databases.Keywords included“Helicobacter pylori“/”children or childhood“/”treatment or eradication.”The risk of bias was evaluated according to the Cochrane Handbook of Systematic Reviews for Interventions.RESULTS Among the 1144 records identified through the database,20 articles were selected.Four studies compared the eradication rates of H.pylori infection between standard triple therapies,changing only the main antibiotic used.Seven studies evaluated the effectiveness of standard triple therapy with the addition of probiotics.One study investigated the relationship between the effectiveness in the eradication rates of standard triple therapy and vitamin E levels.Six studies analyzed the eradication rates of sequential therapy.CONCLUSION The findings suggest that although standard triple therapy is the most recommended regimen for children by the current guidelines,other therapeutic schemes have shown promising results and may also be recommended for clinical practice in the future.展开更多
The security of CPU smart cards, which are widely used throughout China, is currently being threatened by side-channel analysis. Typical countermeasures to side-channel analysis involve adding noise and filtering the ...The security of CPU smart cards, which are widely used throughout China, is currently being threatened by side-channel analysis. Typical countermeasures to side-channel analysis involve adding noise and filtering the power consumption signal. In this paper, we integrate appropriate preprocessing methods with an improved attack strategy to generate a key recovery solution to the shortcomings of these countermeasures. Our proposed attack strategy improves the attack result by combining information leaked from two adjacent clock cycles. Using our laboratory-based power analysis system, we verified the proposed key recovery solution by performing a successful correlation power analysis on a Triple Data Encryption Standard （3DES） hardware module in a real-life 32-bit CPU smart card. All 112 key bits of the 3DES were recovered with about 80 000 power traces.展开更多
文摘BACKGROUND Helicobacter pylori(H.pylori)infection is predominantly acquired in childhood.When indicated,the most accepted treatment for H.pylori eradication in this age group is first-line triple therapy.However,the increasing resistance to clarithromycin and nitroimidazoles has been associated with treatment failure,and thus,alternative treatment regimens have been proposed.AIM To perform a systematic review of randomized controlled trials on treatment regimens for H.pylori infection in children.METHODS We surveyed relevant articles published in English from 2010 to April 2020 in the PubMed and MEDLINE databases.Keywords included“Helicobacter pylori“/”children or childhood“/”treatment or eradication.”The risk of bias was evaluated according to the Cochrane Handbook of Systematic Reviews for Interventions.RESULTS Among the 1144 records identified through the database,20 articles were selected.Four studies compared the eradication rates of H.pylori infection between standard triple therapies,changing only the main antibiotic used.Seven studies evaluated the effectiveness of standard triple therapy with the addition of probiotics.One study investigated the relationship between the effectiveness in the eradication rates of standard triple therapy and vitamin E levels.Six studies analyzed the eradication rates of sequential therapy.CONCLUSION The findings suggest that although standard triple therapy is the most recommended regimen for children by the current guidelines,other therapeutic schemes have shown promising results and may also be recommended for clinical practice in the future.
基金supported by the Major Program“Core of Electronic DevicesHigh-End General Chips+1 种基金and Basis of Software Products”of the Ministry of Industry and Information Technology of China(No.2014ZX01032205)the Key Technologies Research and Development Program of the Twelfth Five-Year Plan of China(No.MMJJ201401009)
文摘The security of CPU smart cards, which are widely used throughout China, is currently being threatened by side-channel analysis. Typical countermeasures to side-channel analysis involve adding noise and filtering the power consumption signal. In this paper, we integrate appropriate preprocessing methods with an improved attack strategy to generate a key recovery solution to the shortcomings of these countermeasures. Our proposed attack strategy improves the attack result by combining information leaked from two adjacent clock cycles. Using our laboratory-based power analysis system, we verified the proposed key recovery solution by performing a successful correlation power analysis on a Triple Data Encryption Standard （3DES） hardware module in a real-life 32-bit CPU smart card. All 112 key bits of the 3DES were recovered with about 80 000 power traces.
