Development of a new cerebral ischemia reperfusion model of Mongolian gerbils and standardized evaluation system

Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symptoms are caused by numerous complex variant types of the circle.Additionally,the lack of an evaluation system for the cer-ebral ischemia/reperfusion(I/R)model of gerbils has shackled the application of this model.Methods:We created a symptom-oriented principle and detailed neurobehavioral scoring criteria.At different time points of reperfusion,we analyzed the alteration in locomotion by rotarod test and grip force score,infarct volume by triphenyltetrazo-lium chloride(TTC)staining,neuron loss using Nissl staining,and histological charac-teristics using hematoxylin-eosin(H&E)straining.Results:With a successful model rate of 56%,32 of the 57 gerbils operated by our method harbored typical features of cerebral I/R injury,and the mortality rate in the male gerbils was significantly higher than that in the female gerbils.The suc-cessfully prepared I/R gerbils demonstrated a significant reduction in motility and grip strength at 1 day after reperfusion;formed obvious infarction;exhibited typi-cal pathological features,such as tissue edema,neuronal atrophy and death,and vacuolated structures;and were partially recovered with the extension of reperfu-sion time.Conclusion:This study developed a new method for the unilateral common carotid artery ligation I/R model of gerbil and established a standardized evaluation system for this model,which could provide a new cerebral I/R model of gerbils with more practical applications.

Standardized ileal digestibility of amino acids in soybean meal fed to non-pregnant and pregnant sows

Background Two studies were designed to determine standard ileal crude protein(CP)and amino acid(AA)digestibility of soybean meal(SBM)from different origins fed to non-pregnant and pregnant sows.Seven solvent-extracted SBMs from soybeans produced in the USA,Brazil,and China were selected.In Exp.1,eight different diets were created:a nitrogen(N)-free diet and 7 experimental diets containing SBM from different origins as the only N source.Eight non-pregnant,multiparous sows were arranged in an 8×8 Latin square design(8 periods and 8 diets).In Exp.2,the diet formula was the same as in Exp.1.Eight gestating sows(parity 3)were assigned to 4 different diets in a replicated 4×3 Youden square design(three periods and four diets)in mid-gestation and again in late-gestation stages.Results When fed to non-pregnant and late-gestating sows,the standardized ileal digestibility(SID)of CP and most AAs from different SBM were not significantly different(P>0.05).When fed to mid-gestating sows,the SID values for Arg,His,Lys,Phe,Cys,Gly,Ser,and Tyr in SBM 1 were lower than in SBM 4 and 5(P<0.05),whereas SID for Leu from SBM 5 was higher than in SBM 1 and 4(P<0.05).SID values for Ile,Ala,and Asp from SBM 4 were lower than in SBM 1 and 5(P<0.05).Sows had significantly greater SID values for Lys,Ala,and Asp during mid-gestation when compared with late-gestation stages(P<0.05).Mid-gestating sows had greater SID value for Val and lower SID value for Tyr when compared with non-pregnant and late-gestating sows(P<0.01),whereas non-pregnant sows had significantly greater SID value for Met when compared with gestating sows(P<0.01).Conclusions When fed to mid-gestating sows,the SID values for most AAs varied among SBM samples.The SID values for Lys,Met,Val,Ala,Asp,and Tyr in SBM were affected by sow gestation stages.Our findings provide a cornerstone for accurate SBM use in sow diets.

Post competency training in standardized training of resident physicians and integrated postgraduates

We focus on the importance and necessity of post-competency-based training in medical education alongside its current challenges and opportunities.Integrating post competency training into standardized educational frameworks is increasingly recognized as a critical component of preparing residents and postgraduates for real-world clinical practice.Post competency training represents a commitment to excellence in medical education,striving to produce competent,skilled practitioners to meet the challenges of modern healthcare.

Characteristics of Dry and Wet Climate in Shandong Province Based on Standardized Precipitation Index

Based on the monthly precipitation data of 116 meteorological stations in Shandong Province during 1970-2021,standardized precipitation index(SPI)was calculated,and the methods of linear fitting,mutation test and Morlet wavelet analysis were used to analyze the change trend and temporal and spatial distribution characteristics of SPI index in the past 52 years.The results show that there were more normal years in Shandong Province,and the frequency reached 38.46%.There was severe drought in the 1980s and more wet years after 2003.SPI index showed an upward trend in spring,summer and winter but a weak arid trend in autumn.In addition,intense dry weather was more frequent in summer.Spatially,the climate was normal or humid in most areas of Shandong Province.The regions with more wet years were located in the central and northeast Shandong and the peninsula,while the climate was normal in the southwest and north of Shandong.The areas with more dry years were mainly located in the northwest of Shandong Province.There was mainly local and global drought in Shandong Province,and the arid area showed a decreasing trend.In the past 52 years,Shandong Province experienced quasi-4 times of alternation between dry and wet climate.The long period of 21 a was the first main period,and the climate would be still wet in Shandong Province in the future.In terms of mutation,the climate in Shandong Province became humid after 2003,and 2003 was the mutation point.After the abrupt change,the climate changed from gradually drying to wetting.

Application Effect of Remote Ultrasound Teaching in Standardized Residency Training

Objective:To explore the application effect of remote ultrasound teaching in the standardized training of residents.Methods:42 students who participated in the standardized residency training in the Department of Ultrasonography of our hospital from August 2022 to August 2023 were selected and divided into the control group(n=21)and the observation group(n=21)by using the random number table method.The control group was taught routinely,and the observation group was taught with remote ultrasound on the basis of the control group.The general data,teaching effect,ultrasound diagnostic compliance rate,and teaching satisfaction of the participants in the two groups were observed.Results:The baseline data of the two groups were not statistically significant(P>0.05);the theoretical and practical assessment scores of the observation group were significantly better than those of the control group(t=2.491,t=2.434,P=0.05);the ultrasound diagnostic compliance rate of the participants in the observation group was significantly higher than that of the control group(78.33%)(χ2=33.574,P=0.000<0.001);the overall satisfaction rate of students in the observation group(20/95.24%)was significantly higher than that of the control group(14/66.67%)(χ2=3.860,P=0.049<0.05).Conclusion:In standardized residency training,remote ultrasound teaching can effectively improve the comprehensive ability of students,enhance diagnostic accuracy,and improve students’teaching satisfaction.

The Effect of Standardized Nutritional Care Combined with Exercise Intervention in Patients with Gestational Diabetes Mellitus and Its Effect on FPG,2hPG,and HbA1c Levels

Objective:To study the application effect of standardized nutritional care combined with exercise intervention in patients with gestational diabetes mellitus and the effect on fasting blood glucose(FPG),2-hour postprandial blood glucose(2hPG),and glycated hemoglobin(HbA1c)levels.Methods:Ninety cases of gestational diabetes mellitus diagnosed between June 2022 and June 2023 were selected and randomly divided into two groups of 45 cases each.The control group received conventional intervention,while the observation group received combined standardized nutritional care and exercise intervention.Blood glucose levels,adverse pregnancy outcomes,and adverse neonatal outcomes were compared.Results:On the day before delivery,the FPG,2hPG,and HbA1c levels of patients in the observation group were lower than those of patients in the control group(P<0.05).The incidence of adverse pregnancy outcomes(4.44%)and adverse neonatal outcomes(2.22%)in the observation group was lower than in the control group(P<0.05).Conclusion:The blood glucose levels of gestational diabetes mellitus patients can be controlled through standardized nutritional care and exercise interventions,leading to improved pregnancy and neonatal outcomes.

Exploration of the Integration of Curriculum Ideology and Politics into the Educational Pathway of Standardized Training for General Practice Residents

In recent years,the national higher education reform has proposed the concept of curriculum ideological and political education as a major element.This integration into the standardized training of general practice residents(commonly referred to as general resident training)is an unavoidable trend in the teaching field.Based on the actual situation of our unit at The First Affiliated Hospital of Xi’an Medical University,this paper emphasizes the necessity of incorporating ideological and political education into the general resident training curriculum,despite the absence of pertinent practical experience in how to effectively incorporate such courses into comprehensive residential training.In our hospital,we must assess the ideological and political education in the curriculum of general resident training,proposing a scientific,reasonable ideological and political education concept system for general practice courses,integrating ideological and political education with general practice resident training,and strengthening the team of ideological and political education physicians to teach them to carry out such education,this would foster enthusiasm and initiative.Strengthening admission education and training for general practice resident training,as well as regularly hosting symposiums to share ideas and understand the mission of doctors can provide effective experience for ideological and political education in general resident training courses.

Influence of standardized nursing intervention combined with mindfulness stress reduction training on the curative effect in patients with acute pancreatitis

BACKGROUND Acute pancreatitis(AP)is a common inflammatory disease of the pancreas with high mortality rates.It is of great significance to take scientific intervention measures for patients with AP in time.AIM To explore the effect of standardized nursing combined with mindfulness stress reduction training on the curative effect,negative emotion,and quality of life in patients with acute pancreatitis.METHODS A total of 80 patients with acute pancreatitis admitted to The First People's Hospital of Jiangxia District Hospital from May 2021 to May 2023 were randomly divided into control group and observation group(n=40).Patients in control group were given the standardized nursing intervention,and the observation group were given standardized nursing plus mindfulness stress reduction training intervention.The time of clinical symptom disappeared or improved,complication occurrence rate,emotional state,and quality of life score of the two groups were observed and compared.RESULTS In comparison with the control group,the bowel sound recovery time,ventosity and abdominal pain improvement time,and venting and cacation time in observation group were shorter,and the total incidence rate of complications was reduced,showing statistically significant difference(P<0.05).The scores of anxiety and depression in observation group were lower than those in control group(P<0.05).Serum levels of tumour necrosis factor alpha,interleukin(IL)-6,IL-1βand IL-8 in observation group were lower than those in control group(P<0.05).The scores of life quality in physiology,psychology,environment and social relations in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).CONCLUSION The application of standardized nursing intervention combined with mindfulness stress reduction training in patients with acute pancreatitis has a definite effect,which can help to ameliorate the clinical symptoms,anxiety and depression of patients,reduce the incidence rate of complications,and improve the prognosis of patients.

Exploring the Application Effect of Flipped Classroom Combined with Problem-Based Learning Teaching Method in Clinical Skills Teaching of Standardized Training for Resident Doctors of Traditional Chinese Medicine

Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese Medicine. Methods: The study used the experimental control method. The study lasted from September to November 2022. The subjects of this study were 49 students of standardized training for resident doctors of traditional Chinese Medicine from grades 2020, 2021 and 2022 of Dazhou integrated TCM & Western Medicine Hospital. They were randomly divided into experiment group (25) and control group (24). The experiment group adopted flipped classroom combined with problem-based learning teaching method, and the control group adopted traditional teaching method. The teaching content was 4 basic clinical skill projects, including four diagnoses of traditional Chinese Medicine, cardiopulmonary resuscitation, dressing change procedure, acupuncture and massage. The evaluation method was carried out by comparing the students’ performance and a self-designed questionnaire was used to investigate the students’ evaluation of the teaching method. Results: The test scores of total scores in the experimental group (90.12 ± 5.89) were all higher than those in the control group (81.47 ± 7.96) (t = 4.53, P P Conclusions: The teaching process of the flipped classroom combined with problem-based learning teaching method is conducive to improving the efficiency of classroom teaching, cultivating students’ self-learning ability, and enhancing students’ willingness to learn.

Clinical study of standard residual liver volume and transient elastography in predicting poor prognosis of patients after hemihepatectomy

BACKGROUND Liver cancer resection,especially in patients with hemihepatectomy or extended hemihepatectomy,often leads to poor prognosis,such as liver insufficiency and even liver failure and death,because the standard residual liver volume(SRLV)cannot be fully compensated after surgery.AIM To explore the risk factors of poor prognosis after hemihepatectomy for hepatocellular carcinoma and evaluate the application value of related prognostic approaches.METHODS The clinical data of 35 patients with primary liver cancer in Nantong Third People's Hospital from February 2016 to July 2020 were retrospectively analyzed.The receiver operating characteristic curve was created using medcac19.0.4 to compare the critical values of the SRLV in different stages of liver fibrosis after hemihepatectomy with those of liver dysfunction after hemihepatectomy.It was constructed by combining the Child-Pugh score to evaluate its application value in predicting liver function compensation.RESULTS The liver stiffness measure(LSM)value and SRLV were associated with liver dysfunction after hemihepatectomy.Logistic regression analysis showed that an LSM value≥25 kPa[odds ratio(OR)=6.254,P<0.05]and SRLV≤0.290 L/m^(2)(OR=5.686,P<0.05)were independent risk factors for postoperative liver dysfunction.The accuracy of the new liver reserve evaluation model for predicting postoperative liver function was higher than that of the Child-Pugh score(P<0.05).CONCLUSION SRLV and LSM values can be used to evaluate the safety of hemihepatectomy.The new liver reserve evaluation model has good application potential in the evaluation of liver reserve function after hemihepatectomy.

Establishing Standardized Nursing Quality Sensitive Indicators

This is a pilot research project was prepared to assess the impact of implementing essential standardized nursing quality sensitive indicators in monitoring, evaluating, and controlling the nursing services and activities which implemented in daily nursing care works with the patients in a health institute, aiming for emphasizing the concept of “nursing quality sensitive indicators” which is valuable to elaborate nursing care performance, and for continuous upgrading of daily nursing care, which hopefully will result in more beneficial outcomes, and lesser negative or undesirable outcomes in all aspects of nursing care, and consequently the health care process, particularly regarding patient safety, patient satisfaction and nursing performance improvement. This pilot research project for the essential standardized nursing quality sensitive indicators was applied in intensive care unit (ICU) department in Qurayyat general hospital, and resulted in excellent improvement of all outcomes correlated with the essential standardized nursing quality sensitive indicators. These essential standardized nursing quality sensitive indicators are hopefully be accepted and accredited by the higher health authorities as standardized nursing quality sensitive indicators in health institutes.

Meteorological Drought Detection and Forecast Using Standardized Precipitation Index and Univariate Distribution Models: Case Study of Bamako, Mali

As an extended period of unusually dry weather conditions without sufficient rain, drought poses enormous risk on societies. Characterized by the absence of precipitation for long periods of time, often resulting in water scarcity, droughts are increasingly posing significant environmental challenges. Drought is therefore considered an important element in the management of water resources, especially groundwater resources during drought. This study therefore sought to investigate the rainfall variability and the frequency of drought for the period 1991 to 2020 in Bamako based on monthly rainfall data from Bamako-Senou gauge station. The standardized precipitation index (SPI) for 12-month, 6-month and 3-month timescales and the SPI for annual totals were used to characterized drought in the study area (Bamako). Univariate parametric probability distributions such as Normal, Log-normal, Gumbel type I and Pearson type III (P3) distributions were fitted with drought variables (severity and duration) for future planning and management. Non-parametric test such as Mann-Kendall trend test was also used to detect trend in annual rainfall data. The results showed that based on 12-month SPI, Bamako experienced two (02) extreme droughts one in July 2002 (SPI = -2.2165) and another in June 2015 (SPI = -2.0598 QUOTE SPI=-2.0598 ). Drought years represented 46.67% for the overall periods according to the SPI for annual totals. The result further indicated that based on the goodness of fit test, the P3 distribution represents the best fitted distribution to both drought severity and duration over Bamako. Bamako is expected to experience several severe severities with higher and shorter duration in the future. Severities with 1, 2, 6, and 10-month duration had return periods ranged from 2.4 to 3.8 years, while 5, 10, 20, 25, 50, and 100-year return periods had 18.51, 26.08, 33.25, 35.50, 42.38, and 49.14 severities, respectively, and durations associated to these severities were 19.8, 26.9, 33.5, 35.6, 42, and 48.2 months, respectively.

Spatio-Temporal Analysis of Drought in the North-Eastern Coastal Region of Vietnam Using the Standardized Precipitation Index (SPI)

Spatio-temporal analysis of drought provides valuable information for drought management and damage mitigation. In this study, the Standardized Precipitation Index at the time scale of 6 months (SPI-6) is selected to reflect drought conditions in the North-Eastern coastal region of Vietnam. The drought events and their characteristics from 1981 to 2019 are detected at 9 meteorological stations and 10 Chirps rainfall stations. The spatio-temporal variation of drought in the study region is analyzed on the basis of the number, duration, severity, intensity, and peak of the detected drought events at the 19 stations. The results show that from 1981 to 2019 the drought events mainly occurred with 1-season duration and moderate intensity and peak. The number, duration, severity, and peak of the drought events were the greatest in the period 2001-2010 and were the smallest in the period 2011-2019. Among the 19 stations, the drought duration tends to decrease at 11 stations, increase at 7 stations, and has a slight variant at 1 station;the drought severity tends to decrease at 14 stations, increase at 4 stations, and has not a significant trend at 1 station;the drought intensity tends to decrease at 17 stations, increase at 1 station, and has a slight variant at 1 station;and the drought peak tends to decrease at 18 stations and increase at 1 station.

Application Research of Fragmented Case Teaching in Standardized Training of Residents in Anesthesiology Department

Objective:To explore the effect of fragmented case teaching in the standardized training of residents in anesthesiology department.Methods:80 doctors who participated in the standardized training of residents in anesthesiology department from January 2021 to January 2022 were selected as the research objects,and the 80 doctors were divided into experimental groups according to the clinical teaching mode(n=40,implemented case fragmented teaching method)and the control group(n=40,traditional teaching method).The training lasted for 2 months,and the medical history collection,medical record analysis,practical operation ability,theoretical assessment results,and the degree of satisfaction towards the training of the two groups of doctors were compared.Results:After 2 months of training,the theoretical knowledge and operational ability of the doctors in the two groups have improved to a certain extent,but the medical history collection,medical record analysis,practical operation ability,theoretical assessment results and satisfaction of the doctors in the experimental group were significantly better than those in the control group(P<0.05).Conclusion:The effect of the fragmented case teaching method in the standardized training of anesthesiology residents is significantly better than the traditional teaching mode.The abilities of doctors have significantly improved after the training.Hence,the fragmented case teaching method is worthy of promotion in clinical practice.

Effectiveness of Participatory Teaching Methods in the Standardized Training of Respiratory Medicine Residents

Objective:To explore and analyze the application effect of participatory teaching method in the standardized training of respiratory medicine residents.Methods:The study period was from May 2022 to May 2023.20 doctors in the standardized training of respiratory medicine residency in our hospital were taken as research subjects and grouped into the participatory group(n=10)and the routine group(n=10)by using the random number lottery method.The participatory group practised participatory teaching methods,and the routine group practised routine teaching methods.The results of discharge assessment,teaching evaluation,and mini-Clinical Evaluation Exercise(mini-CEX)assessment were compared between the groups.Results:The theoretical assessment,operational assessment,and total scores of the participatory group were significantly higher than those of the routine group,and the difference was statistically significant(P<0.05).The teaching evaluation of independent learning,theoretical mastery,teamwork,clinical thinking,communication,and learning interest of the participatory group was significantly higher than that of the routine group,and the difference was statistically significant(P<0.05).The mini-CEX assessments of history inquiry,organizational effectiveness,professionalism,physical examination,clinical diagnosis,communication skills,and overall clinical competence of the participatory group were significantly better than those of the routine group,and the difference was statistically significant(P<0.05).The teaching satisfaction of the participatory group was significantly higher than that of the routine group,the difference was statistically significant(P<0.05).Conclusion:Participatory teaching methods can improve the overall level of doctors in the respiratory medicine residency standardized training,and the teaching satisfaction is improved.

基于湍流模型的飞行器温度场数值仿真研究

飞行器红外成像仿真需要不同飞行条件下的温度场分布。本文利用标准(Standard)k-ε模型、剪切应力传输(SST)k-ε模型和Spalart-Allmaras(S-A)模型分别进行数值模拟仿真计算,研究不同飞行速度和飞行高度下的飞行器温度场分布,并对不同模型的结果进行对比分析。首先,利用MultiGen Creator软件对飞行器进行三维建模;其次采用Hypemesh软件和Fluent meshing软件中进行面网格划分和体网格划分,最后采用Fluent 2022R1软件仿真飞行器静态温度场分布,通过改变湍流模型与边界条件设置,对不同飞行速度和不同高度下飞行器温度场进行数值模拟仿真,并与理论结果进行了对比分析。实验结果显示,3种湍流模型均能较好的模拟飞行器蒙皮与尾喷管内壁壁面温度值。飞行器蒙皮温度随着飞行马赫数的增加不断升高;随着飞行高度的升高而不断地降低,与理论结果变化规律一致。在尾喷管内壁面温度仿真中,3种湍流模型仿真的内壁面温度最高相差21 K,相对误差在1.8%左右,在红外仿真中近似忽略不计,故3种湍流模型均适合尾喷管内壁面温度场仿真。在蒙皮温度场仿真中,3种湍流模型仿真计算的蒙皮平均温度值与理论温度值的相对误差均在5%以内,均可满足红外成像仿真的温度差值要求,其中k-ε模型在蒙皮温度场模拟中与理论温度值最为接近,因此k-ε模型精度更高,更适合于飞行器的流场仿真,能更好地仿真出空气动力加热对飞行器温度场的影响。

The impact of the Rural Minimum Living Standard Guarantee(Rural Dibao)Program on child nutrition outcomes

The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural China.Despite the importance of children’s nutrition in breaking poverty cycles,little is known about the impact of Rural Dibao on child nutrition outcomes.Using China Family Panel Studies(CFPS),this paper examines the effects of Rural Dibao on child nutrition outcomes and investigates potential pathways and heterogeneous effects.We exploit propensity score matching and difference-in-differences techniques to evaluate the effects of the Rural Dibao program on child nutrition outcomes.Our results suggest that Rural Dibao significantly impacts the nutrition outcomes of children up to 15 years of age.Specifically,our results suggest that Rural Dibao improves child height-to-age z-scores by 1.05 standard deviations and lowers the probability of stunting by 11.9 percentage points.Additional analyses suggest that increased protein intake is the main pathway through which Rural Dibao participation contributes to better nutrition outcomes.We also find that the effect of the program is more pronounced among girls,children who are non-left-behind or live with highly educated mothers,and those from low-income families and poor areas.Our findings suggest that Rural Dibao participation helps improve child nutrition outcomes through improving diet quality.

2021-2022年蒙古标准化发展分析:基于获批标准涉及领域的统计

Mongolia,a key partner in the Belt and Road Initiative,is fully dedicated to fostering regional cooperation and connectivity.Standardization has emerged as a vital field with far-reaching influence for regional trade cooperation.This paper makes an in-depth analysis of the standards approved in Mongolia in 2021 and 2022,offering a fresh perspective of the past two years’standardization development in the country.The primary objective is to present an updated account of Mongolia’s standardization efforts and to facilitate regional cooperation and exchange in standardization.

智慧城轨车地一体化机电系统标准体系构建研究

With the rapid development and application of emerging information technologies such as cloud computing,big data,artificial intelligence,5G,satellite communication,and blockchain in urban rail transit,China’s urban rail transit has entered an era of intelligent transformation and upgrading.The development of intelligent systems and the construction of smart urban rail transit have formed a consensus in the industry.The electromechanical system is an important component of urban rail transit engineering,covering power supply stations,vehicles,stations,and lines.The depot and control center are important support for promoting the development of urban rail transit towards informatization and intelligence.However,research on the technical standards for the smart urban rail vehicle-ground integrated electromechanical system has just begun,and a technical standards system has not yet been formed,which cannot better support the electromechanical system.Therefore,it is necessary to conduct research on the technical standards system,propose the common criteria structure and standards list of the standards system,which can provide reference and guidance for the planning and establishment of China’s smart urban rail standards system.

Spatiotemporal characteristics of cultivated land use eco-efficiency and its influencing factors in China from 2000 to 2020

Improving cultivated land use eco-efficiency(CLUE)can effectively promote agricultural sustainability,particularly in developing countries where CLUE is generally low.This study used provincial-level data from China to evaluate the spatiotemporal evolution of CLUE from 2000 to 2020 and identified the influencing factors of CLUE by using a panel Tobit model.In addition,given the undesirable outputs of agricultural production,we incorporated carbon emissions and nonpoint source pollution into the global benchmark-undesirable output-super efficiency-slacks-based measure(GB-US-SBM)model,which combines global benchmark technology,undesirable output,super efficiency,and slacks-based measure.The results indicated that there was an upward trend in CLUE in China from 2000 to 2020,with an increase rate of 2.62%.The temporal evolution of CLUE in China could be classified into three distinct stages:a period of fluctuating decrease(2000-2007),a phase of gradual increase(2008-2014),and a period of rapid growth(2015-2020).The major grain-producing areas(MPAs)had a lower CLUE than their counterparts,namely,non-major grain-production areas(non-MPAs).The spatial agglomeration effect followed a northeast-southwest strip distribution;and the movement path of barycentre revealed a"P"shape,with Luoyang City,Henan Province,as the centre.In terms of influencing factors of CLUE,investment in science and technology played the most vital role in improving CLUE,while irrigation index had the most negative effect.It should be noted that these two influencing factors had different impacts on MPAs and non-MPAs.Therefore,relevant departments should formulate policies to enhance the level of science and technology,improve irrigation condition,and promote sustainable utilization of cultivated land.