We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recov...We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recovered from catheter was surprisingly identified as S. hominis by sequencing of the 16S ribosomal gene. The S. hominis isolate, which is not often associated with infections in dialysis patients, was resistant to methicillin, being mecA positive, and to daptomycin. The patient was successfully treated with vancomycin together with the catheter retirement.展开更多
Staphylococcus hominis is a component of the normal human microflora and is considered to be an opportunistic pathogen that may cause a variety of infections.It has been reported to cause bacteremia,endocarditis and e...Staphylococcus hominis is a component of the normal human microflora and is considered to be an opportunistic pathogen that may cause a variety of infections.It has been reported to cause bacteremia,endocarditis and endophthalmitis.However,abscesses caused by S.hominis are rarely documented.Here,we describe a case of pyogenic liver abscesses caused by S.hominis.Laboratory tests,imaging examinations,and abscess puncture fluid culture were used to identify the etiology and pathogenic bacterium.This case suggests that percutaneous drainage and targeted antibiotic treatment according to the results of antimicrobial susceptibility tests are effective therapeutic approaches for pyogenic liver abscesses caused by S.hominis.展开更多
Prosthetic infection is one of the severe postoperative complications of arthroplasty.Mixed bacterial-fungal prosthetic infection is rare but can be disastrous.This case was a 76-year-old female suffered from prosthet...Prosthetic infection is one of the severe postoperative complications of arthroplasty.Mixed bacterial-fungal prosthetic infection is rare but can be disastrous.This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements.The culture of periprosthetic tissue was bacteriologically sterile following the first debridement,while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered.Thus the pathogen spectrum of anti-infection therapy failed to contain fungus.Ultimately,the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital.The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs.Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty,especially for mixed bacterial-fungal prosthetic infection.展开更多
基金partially supported by grant FIS10/00125 from INSTITUTO DE SALUD CARLOSIII(Spanish Health Ministry)to S.M.-A.
文摘We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recovered from catheter was surprisingly identified as S. hominis by sequencing of the 16S ribosomal gene. The S. hominis isolate, which is not often associated with infections in dialysis patients, was resistant to methicillin, being mecA positive, and to daptomycin. The patient was successfully treated with vancomycin together with the catheter retirement.
基金supported by the Fundamental Research Funds of Shenzhen Research Institute of Shandong University(JCYJ20170818103059486)the National Natural Science Foundation of China(81970522 and 82000542).
文摘Staphylococcus hominis is a component of the normal human microflora and is considered to be an opportunistic pathogen that may cause a variety of infections.It has been reported to cause bacteremia,endocarditis and endophthalmitis.However,abscesses caused by S.hominis are rarely documented.Here,we describe a case of pyogenic liver abscesses caused by S.hominis.Laboratory tests,imaging examinations,and abscess puncture fluid culture were used to identify the etiology and pathogenic bacterium.This case suggests that percutaneous drainage and targeted antibiotic treatment according to the results of antimicrobial susceptibility tests are effective therapeutic approaches for pyogenic liver abscesses caused by S.hominis.
文摘Prosthetic infection is one of the severe postoperative complications of arthroplasty.Mixed bacterial-fungal prosthetic infection is rare but can be disastrous.This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements.The culture of periprosthetic tissue was bacteriologically sterile following the first debridement,while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered.Thus the pathogen spectrum of anti-infection therapy failed to contain fungus.Ultimately,the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital.The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs.Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty,especially for mixed bacterial-fungal prosthetic infection.
