Adverse Effects of Inactivated Foot-and-Mouth Disease Vaccine—Possible Causes Analysis and Countermeasures

Foot-and-mouth disease (FMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, and Chinese government adopts compulsory immunization measures for FMD. The adverse effects of FMD vaccine to pigs, cattle and goats have been reported increasingly frequent during the spring and autumn seasons when large numbers of farm livestock are vaccinated. The financial losses caused by vaccine adverse effects have been a serious concern for both farmers and primary prevention personnel. There are various causative factors reported to involve into adverse effect of FMD vaccine, including the inappropriate vaccine production, transportation and storage, livestock poor tolerance, and unqualified vaccinating manipulations. Symptomatic treatment and early drug prevention have a certain effect on the adverse effects. To analyze causes and propose countermeasures, in the current study possible reasons during the production and processing procedures of inactivated FMD vaccine were reviewed and corresponding countermeasures were recommended. The review may provide references for better use of vaccine to prevent FMD.

Giant Volume Magnetostriction Caused by Itinerant Electron Metamagnetic Transition and Pronounced Invar Effects in La(Fe_xSi_(1-x))_(13) Compounds

A first-order itinerant electron metamagnetic (IEM) transition above the Curie temperature Tc for ferromagnetic La(Fe_xSi_1-x)13 compounds has been confirmed by applying magnetic field. The volume change just above T_C for x=0.88 is huge of about 1.5%, which is caused by a large magnetic moment induced by the IEM transition. These compounds have a possibility for practical applications as giant magnetostrictive materials. Pronounced Invar effects bring about a negative thermal expansion below TC, closely correlated with the negative mode-mode coupling among spin fluctuations.

THE PROTECTIVE EFFECT OF Na^+ CHANNEL BLOCKERS AGAINST CELL DAMAGE CAUSED BY ISCHEMIA

In order to observe it blockers of sodium channel obsesses the neuroprotective effect on hippocampal CA 1 pyramidal cell under the condition of transient brain ischemia, the present experiment used 24 male Wistar rats aged 9 months and divided them into four groups. Lidocaine and/or furosemide were injected introcerebroventicularlly (I.C.V). Stained with H E and accounted the CA 1 pyramidal cell numbers by computer in each group suggested following findings: Although 5 μl of 2% lidocaine was injected I.C.V, the results indicated lidocaine didn't have any blockade to pyramidal cell injuries in hippocampal CA 1 area (P<0 05). In the group medicated with 2 5μl of both 2% lidocaine and 2% furosemide, the results showed that the combined approach had a blockade to injuries of pyramidal cells compared with control group (P<0 01). The present experiment indicates that the combined blockade of lidocaine and furosemide injected I.C.V. to Na + channel can prevent the injuries from hippocampal neurons owing to ischemia.

A Cross-Sectional Study of the Causes, Effects and Management Strategies for Stress and Burnout among Nurses in the Fako Division, Cameroon

Introduction: Stress and burnout are a reality which nurses encounter and try to cope with especially in the Emergency Department (ED) so that they can provide optimal patient care. Nurses who work in ED are front line providers of immediate medical care needed to stabilize patients. With the known critical shortage of health workforce in Cameroon, nurses are overloaded with work and often experience stress and burnout. Aim: This study aimed at determining the causes, effects and management strategies of stress and burnout among nurses working in the ED in hospitals in the Fako Division, Cameroon. Methods: This study was a descriptive cross-sectional study. The sample consisted of seventy nurses from five different hospitals. A purposive sampling technique was used and data was analyzed using SPSS version 16.0. Data was collected using a structured questionnaire developed from the International Stress Management Scale. Results: The highest reported cause of stress in this study was heavy workload (12.88%) and the least was no experience in handling the challenges of the department. The leading reported effect of stress was the development of musculoskeletal disorders such as joint and back pain (16.48%) and the least effect was contemplating quitting the profession (5.99%). The major management strategy used was humour (8.27%), while the least was crying out stress to feel relieved (2.18%). Conclusion: The major cause of stress and burnout among nurses in our study setting was heavy workload, which mostly results in joint and back pain. Moreover, humour was the prime management strategy for stress and burnout among nurses in the emergency department in the study setting. Thus more nurses should be employed and the working conditions of nurses improved to reduce the workload in the study hospitals.

THE FEED BACK INHIBITION EFFECT ON THEINFECTIOUS DEVELOPMENT CAUSED BY N'-ACYL-N-PHENYLHYDRAZINE

The phenyl and methyl phenyl free radicals,formed in the oxidation-hydrolysis process of N’-acyl-N-phenylhydrazine, have been studied by ESR spectrometry.It was found that the free radical is the chief cause which produces the feed-back inhibition effect in the hydrazine-promoted infectious development of silver halide.

The effects of the environmental factors on Laminaria disease caused by alginic acid decomposing bacteria

-The rot disease of Laminaria occurs often in nurseries of sporeling and commercial cultivation in the sea and results in economic loss greatly. Usually the disease outbreaks accompanied with massive multiplication of alginic acid decomposing bacteria. From the section of the decaying Lamuutria which resulted from the inoculation of alginic acid decomposing bacteria, it was observed that the bacteria invaded the epiderm of the Laminaria surface at first, then entered the ex-odermis, endodermis and pith. In addition, there were a great amount of bacteria in the intercellular region and a lot of free cells of the algae in the decaying areas. The wall of some free cells was decomposed, which led to soft tissue or disintegration. Alginic acid decomposing bacteria are normal epiphytic microorganisms growing on Lamuutria surface. These bacteria do not cause disease at normal environmental conditions. The experiments showed that the unfavourable conditions, e. g. , wounding, overcrowding, high temperature reduced the ability of antibacterial activity and made the algae more susceptible to the pathogens and favoured the multiplication of alginic acid decomposing bacteria and finally led to the disease outbreak. The unfavourable environmental factors which resulted from a variety of reasons were the main cause of the disease.

Because-因果句的语义概念化

一个because-因果句的语义概念化就是按照一般逻辑事理,根据言者的知识结构、相关的语境信息和具体的交际目的或意图,把两个事件或现象之间、两个主观认识之间、两个主观行为或这些事件、现象、认识、言语行为相互之间的联系概念化为因果关系。一个because-因果句语义的概念化的方式具体有:象征概念化、推理概念化、语境选择概念化和跨域概念化。

语篇建构的因果关系表征路径研究——以because小句关系的篇章构建为例

语篇建构可以通过不同的路径加以展开,而因果关系表征路径是最常用的方法之一。基于小句关系理论,对BNC语料库中高频因果关系because小句关系进行研究,可以清楚直观地体现出because小句关系表征路径对篇章宏观建构所起的统领和意义延伸的作用,在微观层面上触发篇章建构特殊句式和词汇网络。因果关系表征路径对语篇建构产生影响,也为其他逻辑关系表征在篇章建构过程中的功能分析提供了新的视角,对语言教学与语言学习也具有重要的理论意义和实践意义。

Debates on the Causes of Global Warming

The controversy between the IPCC and Non-governmental IPCC(NIPCC) on the attribution of global warming are reviewed.IPCC holds that today's global warming is mainly due to anthropogenic activities rather than natural variability,which is emphasized by NIPCC.The surface temperature observations since the mid-20th century support the hypothesis of anthropogenic impact,but for the last one hundred years or so,natural forcings such as solar activity, volcanic eruptions and thermohaline circulation variations also have had great influences on the Earth's climate,especially on inter-decadal timescales.In addition,evidence suggests that the Medieval Warm Period(MWP) and Little Ice Age (LIA) are closely associated with the solar activity over the past 1 thousand years.Over the past 10 thousand years, the North Atlantic cold events and solar activity are closely correlated.Nevertheless,the physical mechanisms of the solar-climate variability and interrelation are not well understood,yet.Notably,a prevailing view recently indicates that galactic cosmic rays may result in climatic cooling through modulating global low cloud cover.However,its process and mechanism need to be further investigated.

Causes of Restocking Delays in Absence of Real Time Inventory Tracking of Airtel Airtime

The purpose of this research was to ascertain causes of Restocking Delays in a Distributor Company of Airtel Airtime (AA) that give justification for benefits of using Real Time Inventory Tracking (R.T.I.T) in an attempt to mitigate Restocking Delays. From a study out at the Private Marketing and Trading Services (PMTS) an Authorized Distributor of Airtel Products undertaken in 2017 evidenced by Airtime scratch card and Electronic, E-Recharge Airtime among other forms to encourage R.T.I.T among other products in Telecom Companies and other Business Enterprises. The research comprises of the following areas among which included a detailed focus on a Qualitative and Quantitative approach in obtaining different categories of Restocking Delays in form of Themes and Sub Themes encountered in the Distribution Supply Chain (SC) of AA that is contained in this paper. This research continues to capture an in-depth explanation of the Managerial and Operational causes of restocking delays in respect to AA. Similarly, fast consumer products and services other than AA require a solution to Restocking Delays through implementation of Real Time Inventory Tracking Model (R.T.I.T.M) of AA among Distributor Companies (DCs). This paper also elaborated on Literature, Methodology and Findings obtained from the study. The results were obtained from regression analysis by using the Statistical Package for Social Sciences (SPSS) that showed a higher significance of Stock Turnover Period and Airtime Denomination as a contributor to Restocking Delays whereas Messages from Airtel Head office to the Distributor had a non-significant contribution to restocking Delays as in Figure 9. The research recommends a Model for R.T.I.T in Telecom Distribution SC of AA and Omnichannel Inventory Management (OIM) as a significant contributor to timely reliable inventory restocking and promotes higher sales among DCs and retailers through minimized Restocking Delays. It shows that the forces of Demand and Supply change over time with different tastes and preferences of customers. The imbalance in AA stock levels changes at given times due to unforeseen forces of consumer demand experienced by DCs, explained by the “Bullwhip Effect” due to information distortion in the Supply Chain (SC).

Human Papillomavirus—The Cause of Human Cervical Cancer

Objective: Cervical cancer is the second most prevalent cancer in females worldwide. Infection with human papillomavirus (HPV) is regarded as the main risk factor of cervical cancer. One objective of this study was to conduct a qualitative systematic review of some case-control studies and to examine the role of human papillomavirus (HPV) in the development of human cervical cancer (CC) beyond any reasonable doubt. Methods: We conducted a systematic review and re-analysis of some impressive key studies aimed to answer the following question. Is there a cause-effect relationship between human papillomavirus and cervical cancer? The method of the conditio sine qua non relationship was used to proof the hypothesis whether the presence of human papillomavirus guarantees the presence of cervical carcinoma. In other words, if human cervical cancer is present, then human papillomavirus is present too. The mathematical formula of the causal relationship k was used to proof the hypothesis, whether there is a cause-effect relationship between human papillomavirus and cervical carcinoma. Significance was indicated by a p-value of less than 0.05. Result: The studies analyzed (sample size N = 7657) were able to provide strict evidence that human papillomavirus is a necessary condition (a conditio sine qua non) of cervical carcinoma. Furthermore, the studies analyzed provide impressive evidence of a cause-effect relationship (k = +0.723669245, p value < 0.00001) between human papillomavirus and cervical carcinoma. Conclusion: Human papillomavirus is the cause of human cervical carcinoma.

根因分析法3C护理对消毒供应中心护理质控成效的影响

目的探讨消毒供应中心在开展护理管理过程中运用根因分析法3C护理模式对降低护理缺陷事件发生率以及质控成效的影响。方法福建省立医院消毒供应中心2022年6月1日开始运用根因分析法进行3C护理,分析实施前后各1年(2021年6月—2023年6月)消毒供应中心护理管理工作质量。结果评估实施前后各护理管理质量,实施后环境管理(93.01±3.11)分、安全管理(94.15±1.86)分、物品管理(92.11±1.86)分、检查管理(93.46±1.58)分,均明显高于管理前的(82.14±2.34)分、(81.45±1.86)分、(83.45±1.45)分、(80.05±2.34)分(P<0.05)。随机抽选两观察时间段患者500例,实施后护理缺陷事件发生率为0.20%,低于实施前的5.00%(P<0.05)。实施后院内感染率为1.00%,低于实施前的9.40%(P<0.05)。实施后对消毒供应中心护理工作满意度为98.00%,高于实施前的92.00%(P<0.05)。结论消毒供应中心在开展日常护理管理过程中将根因分析法3C护理进行运用,可以降低护理缺陷事件发生率,提升质量控制效果,对于提升消毒供应中心护理工作质量有重要作用。

若羌库木苏铜矿地质特征及成因初探

库木苏铜矿产于红柳沟-喀腊大湾裂谷带东部卓阿布拉克杂岩体中,为近年来在阿尔金东段奥陶纪辉长岩建造内发现的铜矿产地。通过对库木苏铜矿区成矿地质背景、化探异常、蚀变带及矿体特征的研究,分析成矿环境和控矿因素,初步认为该矿属岩浆硫化物型铜矿床,具良好的找矿潜力。

基于AIE效应的内源性硫化氢荧光探针的研究进展

合理设计监测内源性硫化氢的荧光探针分子有助于充分了解其生理和病理功能.目前,在研的检测硫化氢的小分子荧光探针多存在聚集诱导猝灭效应,因此克服此缺陷的聚集诱导发光效应荧光探针的研究受到越来越多的关注.本文结合研究实践简要综述了近几年具有聚集诱导发光效应的化学反应型硫化氢活体成像荧光探针的研究进展及设计思想并进行展望,以期对该领域研究提供一些借鉴和思考.

玉米“适应性负效应”现象探讨——西南喀斯特石漠化成因新解

南方的石漠化,北方的沙漠化,是困扰中国的两大生态环境问题。为探寻西南喀斯特石漠化的形成原因,利用文献法、参与式田野调查法以及经验实证法,梳理了近四十年来西南喀斯特石漠化形成的各种成因说,并以贵州为例,详细论述了石漠化形成的三个阶段,以及石漠化与玉米的关系。在此基础上揭示了玉米在石漠化地区存在“适应性负效应”,合理地解释了西南喀斯特石漠化形成原因。此观点的提出,可为西南喀斯特石漠化形成原因做出新的阐释,同时也可为西南石漠化治理提供理论支持与科学依据。