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Marijuana Use and the Development of Status Asthmaticus: A Case Report
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作者 Lanteri Alexis S. D. Bhangle K. G. Fless 《Open Journal of Anesthesiology》 2012年第3期62-64,共3页
Introduction: Status asthmaticus is an acute exacerbation of asthma caused by increased airflow resistance and mucus plugging. Symptoms of dyspnea may lead to respiratory failure and cardiac arrest. There is limited k... Introduction: Status asthmaticus is an acute exacerbation of asthma caused by increased airflow resistance and mucus plugging. Symptoms of dyspnea may lead to respiratory failure and cardiac arrest. There is limited knowledge about the effects of marijuana on pulmonary function. We report a unique case of status asthmaticus related to frequent marijuana use. Case Presentation: A 38-year-old African American male with a past medical history of asthma and two prior episodes of status asthmaticus arrived at Saint Barnabas Medical Center with dyspnea and wheezing that was refractory to home albuterol nebulizer therapy. Despite medical treatment his symptoms did not improve and he collapsed to the floor and required intubation and mechanical ventilation. He reported having smoked marijuana numerous times on the day prior to this admission. He was discharged three days later and was strongly advised to stop smoking marijuana. Conclusion: Marijuana is a commonly smoked illicit drug. Although habitual marijuana smokers have symptoms of cough, phlegm and wheezing, we found no reports linking marijuana use to the development of status asthmaticus. Given the rampant abuse of marijuana and its likely burden on healthcare, physicians should be vigilant in discussing the harmful effects of marijuana with asthmatic patients who abuse this drug. 展开更多
关键词 Marijuana status asthmaticus DRUGS of ABUSE
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支气管哮喘患儿发作期血清IL-12、IL-6与ET-1、CEC水平的相关性分析 被引量:3
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作者 陈璐 陈艳萍 +4 位作者 黄建宝 孟燕妮 杨敏 李林瑞 张喜 《医学临床研究》 CAS 2019年第11期2104-2105,2108,共3页
【目的】探讨支气管哮喘患儿发作期血清白细胞介素-12(IL-12)、IL-6与内皮素-1(ET-1)、循环内皮细胞计数(CEC)水平的相关性。【方法】选取本院诊治的90例支气管哮喘患儿,根据患儿病情程度分为稳定期组和发作期组,每组45例。检测并比较血... 【目的】探讨支气管哮喘患儿发作期血清白细胞介素-12(IL-12)、IL-6与内皮素-1(ET-1)、循环内皮细胞计数(CEC)水平的相关性。【方法】选取本院诊治的90例支气管哮喘患儿,根据患儿病情程度分为稳定期组和发作期组,每组45例。检测并比较血清IL-12、IL-6、ET-1、CEC水平,并分析发作期患儿血清IL-12、IL-6与ET-1、CEC的相关性。【结果】支气管哮喘患儿发作期血清IL-12水平低于稳定期,血清IL-6及ET-1、CEC水平高于稳定期,其差异均有统计学意义(P<0.05)。L-12、IL-6与ET-1偏相关系数=0.249,P=0.103,提示IL-12、IL-6与ET-1有直线趋势相关性;IL-12、IL-6与CEC偏相关系数=0.340,P=0.024,提示IL-12、IL-6与CEC有直线相关性。【结论】不同分期支气管哮喘患儿血清IL-12、IL-6、ET-1与CEC差异显著,发作期患儿血清IL-12、IL-6与血清ET-1、CEC关系密切,可有效评估患儿病情及指导临床诊治。 展开更多
关键词 哮喘持续状态/病理生理学 白细胞介素-6 白细胞介素-12
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