BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHOD...BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.展开更多
BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely a...BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.展开更多
目的探讨机器人引导下穿刺引流10~30 mL脑内小血肿的临床效果。方法采用回顾性病例对照研究。选取2019年1月至2022年12月在梅州市人民医院接受治疗的83例高血压脑出血患者,依据治疗方法不同分为机器人手术组(观察组)39例和保守治疗组(...目的探讨机器人引导下穿刺引流10~30 mL脑内小血肿的临床效果。方法采用回顾性病例对照研究。选取2019年1月至2022年12月在梅州市人民医院接受治疗的83例高血压脑出血患者,依据治疗方法不同分为机器人手术组(观察组)39例和保守治疗组(对照组)44例。比较两组患者临床效果、住院期间并发症发生情况、住院时间及住院费用、出院时及出院3个月时基础性日常生活能力量表(basic activity of daily living scale,BADL)评分及美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分。结果①入院时两组NIHSS评分和BADL评分无统计学差异(P>0.05);但出院时、出院3个月随访时观察组NIHSS评分更低(P<0.05),BADL评分更高(P<0.05)。②观察组和对照组的平均住院时间分别为(12.8±3.3)d和(13.8±4.0)d,两组比较无统计学差异(P=0.252)。观察组和对照组的住院费用分别为(38496.23±6369.06)元和(19258.36±4068.68)元,观察组高于对照组(P<0.05)。③观察组和对照组的并发症发生率分别为2.6%(1/39)和6.8%(3/44)。观察组发生穿刺行程区出血1例,对照组并发肺部感染3例,两组比较无统计学差异(P>0.05)。结论机器人引导下穿刺引流10~30 mL脑内小血肿的疗效较好,术后并发症少,操作便捷简单,可促进患者术后功能的恢复,有效提高患者的生活质量。展开更多
目的分析立体定向颅内血肿穿刺引流术与保守治疗幕上中等量(15~40 mL)自发性高血压脑出血的疗效及安全性。方法根据设定的检索策略,检索中国知网、万方、维普、中国生物医学文献服务系统、PubMed、Cochranelibrary、Embase、Web of scie...目的分析立体定向颅内血肿穿刺引流术与保守治疗幕上中等量(15~40 mL)自发性高血压脑出血的疗效及安全性。方法根据设定的检索策略,检索中国知网、万方、维普、中国生物医学文献服务系统、PubMed、Cochranelibrary、Embase、Web of science数据库,利用RevMan5.4软件对纳入的研究按照不同观察指标[平均住院时间、平均住院费用、血肿清除率、美国国立卫生研究院卒中量表(NIHSS)评分、术后并发症、预后评分、病死率]进行Meta分析。结果收集符合标准的12篇文献,共1264例高血压脑出血病例,其中进行立体定向手术(立体定向组)681例,保守治疗(保守治疗组)583例。两组患者在手术后消化道出血发生率比较,差异无统计学意义(OR=1.19,95%CI:0.36~3.89,P>0.05)。与保守治疗组比较,立体定向组在平均住院时间和住院费用、血肿清除率、术后NIHSS评分、术后并发症、预后评分、病死率方面更有优势,差异有统计学意义(P<0.05)。结论立体定向颅内血肿穿刺引流术是治疗中等量高血压性脑出血的一种微创手术方法,较保守治疗效果确切,并发症发生率更低,利于临床开展,更能使患者获益。展开更多
基金supported by a grant from Shanghai Pudong New Area(PWZxkq2011-01)
文摘BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.
文摘BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.
文摘目的探讨机器人引导下穿刺引流10~30 mL脑内小血肿的临床效果。方法采用回顾性病例对照研究。选取2019年1月至2022年12月在梅州市人民医院接受治疗的83例高血压脑出血患者,依据治疗方法不同分为机器人手术组(观察组)39例和保守治疗组(对照组)44例。比较两组患者临床效果、住院期间并发症发生情况、住院时间及住院费用、出院时及出院3个月时基础性日常生活能力量表(basic activity of daily living scale,BADL)评分及美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分。结果①入院时两组NIHSS评分和BADL评分无统计学差异(P>0.05);但出院时、出院3个月随访时观察组NIHSS评分更低(P<0.05),BADL评分更高(P<0.05)。②观察组和对照组的平均住院时间分别为(12.8±3.3)d和(13.8±4.0)d,两组比较无统计学差异(P=0.252)。观察组和对照组的住院费用分别为(38496.23±6369.06)元和(19258.36±4068.68)元,观察组高于对照组(P<0.05)。③观察组和对照组的并发症发生率分别为2.6%(1/39)和6.8%(3/44)。观察组发生穿刺行程区出血1例,对照组并发肺部感染3例,两组比较无统计学差异(P>0.05)。结论机器人引导下穿刺引流10~30 mL脑内小血肿的疗效较好,术后并发症少,操作便捷简单,可促进患者术后功能的恢复,有效提高患者的生活质量。
文摘目的分析立体定向颅内血肿穿刺引流术与保守治疗幕上中等量(15~40 mL)自发性高血压脑出血的疗效及安全性。方法根据设定的检索策略,检索中国知网、万方、维普、中国生物医学文献服务系统、PubMed、Cochranelibrary、Embase、Web of science数据库,利用RevMan5.4软件对纳入的研究按照不同观察指标[平均住院时间、平均住院费用、血肿清除率、美国国立卫生研究院卒中量表(NIHSS)评分、术后并发症、预后评分、病死率]进行Meta分析。结果收集符合标准的12篇文献,共1264例高血压脑出血病例,其中进行立体定向手术(立体定向组)681例,保守治疗(保守治疗组)583例。两组患者在手术后消化道出血发生率比较,差异无统计学意义(OR=1.19,95%CI:0.36~3.89,P>0.05)。与保守治疗组比较,立体定向组在平均住院时间和住院费用、血肿清除率、术后NIHSS评分、术后并发症、预后评分、病死率方面更有优势,差异有统计学意义(P<0.05)。结论立体定向颅内血肿穿刺引流术是治疗中等量高血压性脑出血的一种微创手术方法,较保守治疗效果确切,并发症发生率更低,利于临床开展,更能使患者获益。
