Under the wave of global technological revolution,the new materials industry is facing difficulties in innovation and transformation.Equity investment has become a key driving force due to its flexible mechanism,risk ...Under the wave of global technological revolution,the new materials industry is facing difficulties in innovation and transformation.Equity investment has become a key driving force due to its flexible mechanism,risk sharing,and deep participation.Based on introducing the current development status of China’s new materials industry,this article reveals the mechanism of equity investment in financial support,risk management,incentive constraints,and resource integration.The article proposes optimization strategies,such as building an information-sharing mechanism and a diversified investment fund system,to promote the high-quality development of the new materials industry driven by innovation and provide strategic guidance for policymakers,investors,and enterprises.展开更多
The efforts Xiamen has made in ecological protection over the last 20 years have helped it become a beautiful and clean city.TWENTY years ago,I had the opportunity to travel to the city of Xiamen in southeastern China...The efforts Xiamen has made in ecological protection over the last 20 years have helped it become a beautiful and clean city.TWENTY years ago,I had the opportunity to travel to the city of Xiamen in southeastern China’s Fujian Province.Unfortunately,due to the fact that I was in a rush,I did not have the chance to see the whole city.My memory of Xiamen was its pleasant climate and unforgettable beauty-I knew if I ever got the opportunity,I would revisit this place.Twenty years went by until I was able to return to this city again.After emerging from the airport,I realized that I had grown older,while Xiamen was becoming increasingly youthful and vibrant.What exactly had given this city such vitality?展开更多
BACKGROUND Malignant transformation(MT)of mature cystic teratoma(MCT)has a poor prognosis,especially in advanced cases.Concurrent chemoradiotherapy(CCRT)has an inhibitory effect on MT.CASE SUMMARY Herein,we present a ...BACKGROUND Malignant transformation(MT)of mature cystic teratoma(MCT)has a poor prognosis,especially in advanced cases.Concurrent chemoradiotherapy(CCRT)has an inhibitory effect on MT.CASE SUMMARY Herein,we present a case in which CCRT had a reduction effect preoperatively.A 73-year-old woman with pyelonephritis was referred to our hospital.Computed tomography revealed right hydronephrosis and a 6-cm pelvic mass.Endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)revealed squamous cell carci-noma.The patient was diagnosed with MT of MCT.Due to her poor general con-dition and renal malfunction,we selected CCRT,expecting fewer adverse effects.After CCRT,her performance status improved,and the tumor size was reduced;surgery was performed.Five months postoperatively,the patient developed dis-semination and lymph node metastases.Palliative chemotherapy was ineffective.She died 18 months after treatment initiation.CONCLUSION EUS-FNB was useful in the diagnosis of MT of MCT;CCRT suppressed the disea-se and improved quality of life.展开更多
In this paper, we theoretically analyze the transformation of marketing strategy and the countermeasures under the network economic times. Network marketing is based on the network technology, including the whole proc...In this paper, we theoretically analyze the transformation of marketing strategy and the countermeasures under the network economic times. Network marketing is based on the network technology, including the whole process of marketing activities as a new form of marketing. In this paper, we analyze the issue from the listed perspectives. (1) Ultra space-and-time. The traditional marketing has very strong boundedness to the region, and this boundedness displays, the specifi c transaction can only be closed in the specific region, if the enterprise wants to expand the market share, only then establishes the retailing organization. (2) Interactivity. Network as a media, with the one-on-one interaction, this feature allows companies to basic communicate with consumers, and strengthen consumer participation, to determine the product form, function and the price. (3) The symmetry of information. Consumers can fi nd all kinds of that related products on the Internet information, there are plenty of time to judge the various products and prices. Companies will also be released in a timely manner on the Internet the company’s latest product information. Under this basis, we propose the new idea on the network marketing development direction that will help to build up the more efficient marketing system.展开更多
AIM:To investigate the role of 64-slice computed tomography(CT) in portal vein cavernous transformation to determine surgical strategy.METHODS:The site of lesions and extent of collateral circulation in 12 pediatric c...AIM:To investigate the role of 64-slice computed tomography(CT) in portal vein cavernous transformation to determine surgical strategy.METHODS:The site of lesions and extent of collateral circulation in 12 pediatric cases of cavernous transformation of the portal vein with surgical treatment were analyzed.RESULTS:Eleven of 12 children had esophageal varices and were treated with lower esophageal and gastric devascularization and splenectomy,and the other case was only treated with splenectomy.There were eight cases with spontaneous spleen/stomach-renal shunt,four with Retzius vein opening,which was reserved during surgery.Three cases of lesions involving the intrahepatic portal vein(PV) were treated with living donor liver transplantation.One patient died from PV thrombosis after liver transplantation,and the rest had no significant complications.CONCLUSION:The PV,its branches and collateral circulation were clearly seen by 64-slice spiral CT angiography,which helped with preoperative surgical planning.展开更多
Identity authentication is the first line of defense for network security.Passwords have been the most widely used authentication method in recent years.Although there are security risks in passwords,they will be the ...Identity authentication is the first line of defense for network security.Passwords have been the most widely used authentication method in recent years.Although there are security risks in passwords,they will be the primary method in the future due to their simplicity and low cost.Considering the security and usability of passwords,we propose AvoidPwd,which is a novel mnemonic password generation strategy that is based on keyboard transformation.AvoidPwd helps users customize a“route”to bypass an“obstacle”and choose the characters on the“route”as the final password.The“obstacle”is a certain word using any language and the keys adjacent to the“obstacle”are typed with the“Shift”key.A two-part experiment was conducted to examine the memorability and security of the AvoidPwd strategy with other three password strategies and three leaked password sets.The results showed that the passwords generated by the AvoidPwd strategy were more secure than the other leaked password sets.Meanwhile,AvoidPwd outperformed the KbCg,SpIns,and Alphapwd in balancing security and usability.In addition,there are more symbols in the character distribution of AvoidPwd than the other strategies.AvoidPwd is hopeful to solve the security problem that people are difficult to remember symbols and they tend to input letters and digits when creating passwords.展开更多
Sustainable income growth and poverty reduction remain critical challenges at the forefront of research in Pakistan,particularly in rural areas.To overcome these challenges,the role of rural transformation(RT)has emer...Sustainable income growth and poverty reduction remain critical challenges at the forefront of research in Pakistan,particularly in rural areas.To overcome these challenges,the role of rural transformation(RT)has emerged and gained importance in recent years.The present study is based on district-level data and covers the period from 1981 to 2019.The study attempts to quantify the role of rural transformation in boosting rural per capita income and alleviating rural poverty in the country.The study also aims to explore the impact of stages of rural transformation on rural per capita income and rural poverty alleviation.The empirical findings reveal that rural transformation(RT_(1)and RT_(2))is essential in enhancing rural per capita income and alleviating rural poverty.The role of the share of high-value crops(RT_(1))is more pronounced than the share of non-farm employment(RT_(2))in boosting rural per capita income and poverty alleviation.The trend of larger contribution of RT_(1)to enhance rural per capita income also continued at 2nd stage of rural transformation.In the case of poverty reduction,at 3rd stage of rural transformation,the role of RT_(2)is dominant.Our results indicate that districts at higher stages of rural transformation(both RT_(1)and RT_(2))tend to correlate positively with increased rural per capita income and reduced poverty rates,suggesting that progress in rural transformation is associated with improved economic conditions.However,it is important to note that this correlation does not necessarily imply a direct causal relationship between rural transformation and these economic outcomes;other factors may have influenced this relationship.In addition,the welfare impacts are more noticeable among the districts where a simultaneous shift from grain crops to cash crops and from farm employment to non-farm employment is observed.The study provides baseline information to learn experiences from fast-growing districts and to replicate the strategies in other districts,which boosts the RT process that may increase rural per capita income and enhance poverty reduction efforts.展开更多
BACKGROUND Intensive care unit-acquired weakness(ICU-AW)is a common complication that significantly impacts the patient's recovery process,even leading to adverse outcomes.Currently,there is a lack of effective pr...BACKGROUND Intensive care unit-acquired weakness(ICU-AW)is a common complication that significantly impacts the patient's recovery process,even leading to adverse outcomes.Currently,there is a lack of effective preventive measures.AIM To identify significant risk factors for ICU-AW through iterative machine learning techniques and offer recommendations for its prevention and treatment.METHODS Patients were categorized into ICU-AW and non-ICU-AW groups on the 14th day post-ICU admission.Relevant data from the initial 14 d of ICU stay,such as age,comorbidities,sedative dosage,vasopressor dosage,duration of mechanical ventilation,length of ICU stay,and rehabilitation therapy,were gathered.The relationships between these variables and ICU-AW were examined.Utilizing iterative machine learning techniques,a multilayer perceptron neural network model was developed,and its predictive performance for ICU-AW was assessed using the receiver operating characteristic curve.RESULTS Within the ICU-AW group,age,duration of mechanical ventilation,lorazepam dosage,adrenaline dosage,and length of ICU stay were significantly higher than in the non-ICU-AW group.Additionally,sepsis,multiple organ dysfunction syndrome,hypoalbuminemia,acute heart failure,respiratory failure,acute kidney injury,anemia,stress-related gastrointestinal bleeding,shock,hypertension,coronary artery disease,malignant tumors,and rehabilitation therapy ratios were significantly higher in the ICU-AW group,demonstrating statistical significance.The most influential factors contributing to ICU-AW were identified as the length of ICU stay(100.0%)and the duration of mechanical ventilation(54.9%).The neural network model predicted ICU-AW with an area under the curve of 0.941,sensitivity of 92.2%,and specificity of 82.7%.CONCLUSION The main factors influencing ICU-AW are the length of ICU stay and the duration of mechanical ventilation.A primary preventive strategy,when feasible,involves minimizing both ICU stay and mechanical ventilation duration.展开更多
Hemorrhagic transformation is a major complication of large-artery atheroscle rotic stroke(a major ischemic stro ke subtype)that wo rsens outcomes and increases mortality.Disruption of the gut microbiota is an importa...Hemorrhagic transformation is a major complication of large-artery atheroscle rotic stroke(a major ischemic stro ke subtype)that wo rsens outcomes and increases mortality.Disruption of the gut microbiota is an important feature of stroke,and some specific bacteria and bacterial metabolites may contribute to hemorrhagic transformation pathogenesis.We aimed to investigate the relationship between the gut microbiota and hemorrhagic transformation in largearte ry atheroscle rotic stro ke.An observational retrospective study was conducted.From May 2020 to September 2021,blood and fecal samples were obtained upon admission from 32 patients with first-ever acute ischemic stroke and not undergoing intravenous thrombolysis or endovascular thrombectomy,as well as 16 healthy controls.Patients with stro ke who developed hemorrhagic transfo rmation(n=15)were compared to those who did not develop hemorrhagic transformation(n=17)and with healthy controls.The gut microbiota was assessed through 16S ribosomal ribonucleic acid sequencing.We also examined key components of the lipopolysaccharide pathway:lipopolysaccharide,lipopolysaccharide-binding protein,and soluble CD14.We observed that bacterial diversity was decreased in both the hemorrhagic transformation and non-hemorrhagic transfo rmation group compared with the healthy controls.The patients with ischemic stro ke who developed hemorrhagic transfo rmation exhibited altered gut micro biota composition,in particular an increase in the relative abundance and dive rsity of members belonging to the Enterobacteriaceae family.Plasma lipopolysaccharide and lipopolysaccharide-binding protein levels were higher in the hemorrhagic transformation group compared with the non-hemorrhagic transfo rmation group.lipopolysaccharide,lipopolysaccharide-binding protein,and soluble CD14 concentrations were associated with increased abundance of Enterobacte riaceae.Next,the role of the gut microbiota in hemorrhagic transformation was evaluated using an experimental stroke rat model.In this model,transplantation of the gut microbiota from hemorrhagic transformation rats into the recipient rats triggered higher plasma levels of lipopolysaccharide,lipopolysaccharide-binding protein,and soluble CD14.Ta ken togethe r,our findings demonstrate a noticeable change in the gut microbiota and lipopolysaccharide-related inflammatory response in stroke patients with hemorrhagic transformation.This suggests that maintaining a balanced gut microbiota may be an important factor in preventing hemorrhagic transfo rmation after stro ke.展开更多
The pursuit-evasion game models the strategic interaction among players, attracting attention in many realistic scenarios, such as missile guidance, unmanned aerial vehicles, and target defense. Existing studies mainl...The pursuit-evasion game models the strategic interaction among players, attracting attention in many realistic scenarios, such as missile guidance, unmanned aerial vehicles, and target defense. Existing studies mainly concentrate on the cooperative pursuit of multiple players in two-dimensional pursuit-evasion games. However, these approaches can hardly be applied to practical situations where players usually move in three-dimensional space with a three-degree-of-freedom control. In this paper,we make the first attempt to investigate the equilibrium strategy of the realistic pursuit-evasion game, in which the pursuer follows a three-degree-of-freedom control, and the evader moves freely. First, we describe the pursuer's three-degree-of-freedom control and the evader's relative coordinate. We then rigorously derive the equilibrium strategy by solving the retrogressive path equation according to the Hamilton-Jacobi-Bellman-Isaacs(HJBI) method, which divides the pursuit-evasion process into the navigation and acceleration phases. Besides, we analyze the maximum allowable speed for the pursuer to capture the evader successfully and provide the strategy with which the evader can escape when the pursuer's speed exceeds the threshold. We further conduct comparison tests with various unilateral deviations to verify that the proposed strategy forms a Nash equilibrium.展开更多
To study the formation and transformation mechanism of long-period stacked ordered(LPSO)structures,a systematic atomic scale analysis was conducted for the structural evolution of long-period stacked ordered(LPSO)stru...To study the formation and transformation mechanism of long-period stacked ordered(LPSO)structures,a systematic atomic scale analysis was conducted for the structural evolution of long-period stacked ordered(LPSO)structures in the Mg-Gd-Y-Zn-Zr alloy annealed at 300℃~500℃.Various types of metastable LPSO building block clusters were found to exist in alloy structures at different temperatures,which precipitate during the solidification and homogenization process.The stability of Zn/Y clusters is explained by the first principles of density functional theory.The LPSO structure is distinguished by the arrangement of its different Zn/Y enriched LPSO structural units,which comprises local fcc stacking sequences upon a tightly packed plane.The presence of solute atoms causes local lattice distortion,thereby enabling the rearrangement of Mg atoms in the different configurations in the local lattice,and local HCP-FCC transitions occur between Mg and Zn atoms occupying the nearest neighbor positions.This finding indicates that LPSO structures can generate necessary Schockley partial dislocations on specific slip surfaces,providing direct evidence of the transition from 18R to 14H.Growth of the LPSO,devoid of any defects and non-coherent interfaces,was observed separately from other precipitated phases.As a result,the precipitation sequence of LPSO in the solidification stage was as follows:Zn/Ycluster+Mg layers→various metastable LPSO building block clusters→18R/24R LPSO;whereas the precipitation sequence of LPSO during homogenization treatment was observed to be as follows:18R LPSO→various metastable LPSO building block clusters→14H LPSO.Of these,14H LPSO was found to be the most thermodynamically stable structure.展开更多
The development of the existing building energy-saving transformation market is inseparable from the internal driving force of ESCO.Giving full play to the driving role of ESCO scientifically is the internal requireme...The development of the existing building energy-saving transformation market is inseparable from the internal driving force of ESCO.Giving full play to the driving role of ESCO scientifically is the internal requirement to promote the healthy and orderly operation of the existing building energy-saving transformation market.This paper summarizes the practical experience of developing ESCO driving force operation in foreign existing building energy-saving transformation market,analyzes the bottleneck of developing ESCO driving force operation in China’s existing building energy-saving transformation market,and puts forward useful practical enlightenment based on the comparison between home and abroad;According to the optimization principle of ESCO driving force operation in the development of existing building energy-saving transformation market,the optimization design framework of ESCO driving force is proposed,and the implementation strategy of ESCO driving force optimization in the development of existing building energy-saving transformation market is planned.In order to optimize and improve the effectiveness of the operation and development of the energy-saving transformation market of existing buildings with the internal driving force of ESCO.展开更多
The comprehensive pilot of China Telecom transformation was unveiled in Pudong of Shanghai a few days ago, which indicates comprehensive pilot projects starting formally. Huang WenLin, Vice President of China Telecom,...The comprehensive pilot of China Telecom transformation was unveiled in Pudong of Shanghai a few days ago, which indicates comprehensive pilot projects starting formally. Huang WenLin, Vice President of China Telecom, attends the unveiling ceremony and proposes four requirements.展开更多
Time-series data provide important information in many fields,and their processing and analysis have been the focus of much research.However,detecting anomalies is very difficult due to data imbalance,temporal depende...Time-series data provide important information in many fields,and their processing and analysis have been the focus of much research.However,detecting anomalies is very difficult due to data imbalance,temporal dependence,and noise.Therefore,methodologies for data augmentation and conversion of time series data into images for analysis have been studied.This paper proposes a fault detection model that uses time series data augmentation and transformation to address the problems of data imbalance,temporal dependence,and robustness to noise.The method of data augmentation is set as the addition of noise.It involves adding Gaussian noise,with the noise level set to 0.002,to maximize the generalization performance of the model.In addition,we use the Markov Transition Field(MTF)method to effectively visualize the dynamic transitions of the data while converting the time series data into images.It enables the identification of patterns in time series data and assists in capturing the sequential dependencies of the data.For anomaly detection,the PatchCore model is applied to show excellent performance,and the detected anomaly areas are represented as heat maps.It allows for the detection of anomalies,and by applying an anomaly map to the original image,it is possible to capture the areas where anomalies occur.The performance evaluation shows that both F1-score and Accuracy are high when time series data is converted to images.Additionally,when processed as images rather than as time series data,there was a significant reduction in both the size of the data and the training time.The proposed method can provide an important springboard for research in the field of anomaly detection using time series data.Besides,it helps solve problems such as analyzing complex patterns in data lightweight.展开更多
A large-scale fine-grained Mg-Gd-Y-Zn-Zr alloy plate with high strength and ductility was successfully prepared by multi-pass friction stir processing(MFSP)technology in this work.The structure of grains and long peri...A large-scale fine-grained Mg-Gd-Y-Zn-Zr alloy plate with high strength and ductility was successfully prepared by multi-pass friction stir processing(MFSP)technology in this work.The structure of grains and long period stacking ordered(LPSO)phase were characterized,and the mechanical properties uniformity was investigated.Moreover,a quantitative relationship between the microstructure and tensile yield strength was established.The results showed that the grains in the processed zone(PZ)and interfacial zone(IZ)were refined from 50μm to 3μm and 4μm,respectively,and numerous original LPSO phases were broken.In IZ,some block-shaped 18R LPSO phases were transformed into needle-like 14H LPSO phases due to stacking faults and the short-range diffusion of solute atoms.The severe shear deformation in the form of kinetic energy caused profuse stacking fault to be generated and move rapidly,greatly increasing the transformation rate of LPSO phase.After MFSP,the ultimate tensile strength,yield strength and elongation to failure of the large-scale plate were 367 MPa,305 MPa and 18.0% respectively.Grain refinement and LPSO phase strengthening were the major strengthening mechanisms for the MFSP sample.In particularly,the strength of IZ was comparable to that of PZ because the strength contribution of the 14H LPSO phase offsets the lack of grain refinement strengthening in IZ.This result opposes the widely accepted notion that IZ is a weak region in MFSP-prepared large-scale fine-grained plate.展开更多
Background: Cavernous transformation of the portal vein(CTPV) due to portal vein obstruction is a rare vascular anomaly defined as the formation of multiple collateral vessels in the hepatic hilum. This study aimed to...Background: Cavernous transformation of the portal vein(CTPV) due to portal vein obstruction is a rare vascular anomaly defined as the formation of multiple collateral vessels in the hepatic hilum. This study aimed to investigate the imaging features of intrahepatic portal vein in adult patients with CTPV and establish the relationship between the manifestations of intrahepatic portal vein and the progression of CTPV. Methods: We retrospectively analyzed 14 CTPV patients in Beijing Tsinghua Changgung Hospital. All patients underwent both direct portal venography(DPV) and computed tomography angiography(CTA) to reveal the manifestations of the portal venous system. The vessels measured included the left portal vein(LPV), right portal vein(RPV), main portal vein(MPV) and the portal vein bifurcation(PVB). Results: Nine males and 5 females, with a median age of 40.5 years, were included in the study. No significant difference was found in the diameters of the LPV or RPV measured by DPV and CTA. The visualization in terms of LPV, RPV and PVB measured by DPV was higher than that by CTA. There was a significant association between LPV/RPV and PVB/MPV in term of visibility revealed with DPV( P = 0.01), while this association was not observed with CTA. According to the imaging features of the portal vein measured by DPV, CTPV was classified into three categories to facilitate the diagnosis and treatment. Conclusions: DPV was more accurate than CTA for revealing the course of the intrahepatic portal vein in patients with CTPV. The classification of CTPV, that originated from the imaging features of the portal vein revealed by DPV, may provide a new perspective for the diagnosis and treatment of CTPV.展开更多
Digital transformation of education is an important strategic content of information construction in Chinese universities in recent years. Postgraduate education is characterized by many types of postgraduates, comple...Digital transformation of education is an important strategic content of information construction in Chinese universities in recent years. Postgraduate education is characterized by many types of postgraduates, complex training links, long training process, and obvious individuation. Its information construction and digital transformation are the difficulties in the construction of smart campus in colleges and universities. This paper discusses the current situation and main problems of postgraduate education informatization in colleges and universities, and puts forward the key points and suggestions of digital transformation of postgraduate education in colleges and universities from the aspects of optimizing the information platform of postgraduate education management and service, driving the modernization and wisdom of postgraduate education with data, constructing the integrated platform of intelligent teaching, and continuously improving the digital literacy of teachers and students.展开更多
During the Cold War,the United States implemented an"offshore balance"policy in the Middle East,on the one hand,competing with the Soviet Union for a sphere of influence,and on the other hand,not directly en...During the Cold War,the United States implemented an"offshore balance"policy in the Middle East,on the one hand,competing with the Soviet Union for a sphere of influence,and on the other hand,not directly engaging in the war.After the end of the Cold War,the US,as the sole super power,switched to the strategy of direct intervention in the Middle East.展开更多
Since the emergence of COVID-19 in 2020,the threaten of emerging infectious diseases(EIDs)has attracted great attentions and echoes either from professional institutions,governments or public.The conceptualization of...Since the emergence of COVID-19 in 2020,the threaten of emerging infectious diseases(EIDs)has attracted great attentions and echoes either from professional institutions,governments or public.The conceptualization of“Disease X”,which covers more than 30 families of viruses,has strongly actuated various resources into the development of medical countermeasures and the research across all families of pathogens.On the other hand,the endemic even pandemic old communicable diseases,such as tuberculosis(TB),malaria,HIV/AIDS,etc.,should never be neglected.Globally in 2023,the estimated TB cases was 10.8 million and the estimated deaths was 1.25 million according to the Global Tuberculosis Report 2024 by World Health Organization(WHO)[1].The most affected countries are India,Indonesia,China,the Philippines,Pakistan,Nigeria,Bangladesh,and the Democratic Republic of the Congo.展开更多
It is well-known that elevated low-density lipoprotein cholesterol(LDL-C)is a causal risk factor for atheroscler-otic cardiovascular disease(ASCVD),statins are cornerstone drugs for the cause-based treatment of ASCVD,...It is well-known that elevated low-density lipoprotein cholesterol(LDL-C)is a causal risk factor for atheroscler-otic cardiovascular disease(ASCVD),statins are cornerstone drugs for the cause-based treatment of ASCVD,which has created a new era for ASCVD therapy.However,statin intolerance is not clinically uncommon,which there are several issues with confu-sion and misunderstandings.Hence,a file named Chinese Expert Consensus on the Diagnosis and Management Strategy of Pa-tients With Statin Intolerance,like a navigator,has recently been published written by a team of experts from the Cardiovascular Metabolic Medicine Professional Committee,Expert Committee of the National Center for Cardiovascular Diseases aiming to en-hance the standardized clinical application of statins and improve the prevention and clinical outcome.In this article,author briefly summarized the key points of above consensus in order to helping to comprehending the content of the consensus sugges-tions.展开更多
基金Shenzhen Polytechnical University School level Scientific Research Projects 2023:“Research on the Path and Mechanism of Equity Investment in the Innovation Achievement Transformation of New Material Industry from the Perspective of Intermediary Effect”(Project No.6023310014S)Shenzhen Polytechnical University Postdoctoral Outstation Late Stage Funding Project:“Research on the Cultivation of Digital Trade Talents in the Guangdong Hong Kong Macao Greater Bay Area”(Project No.6023271012S)。
文摘Under the wave of global technological revolution,the new materials industry is facing difficulties in innovation and transformation.Equity investment has become a key driving force due to its flexible mechanism,risk sharing,and deep participation.Based on introducing the current development status of China’s new materials industry,this article reveals the mechanism of equity investment in financial support,risk management,incentive constraints,and resource integration.The article proposes optimization strategies,such as building an information-sharing mechanism and a diversified investment fund system,to promote the high-quality development of the new materials industry driven by innovation and provide strategic guidance for policymakers,investors,and enterprises.
文摘The efforts Xiamen has made in ecological protection over the last 20 years have helped it become a beautiful and clean city.TWENTY years ago,I had the opportunity to travel to the city of Xiamen in southeastern China’s Fujian Province.Unfortunately,due to the fact that I was in a rush,I did not have the chance to see the whole city.My memory of Xiamen was its pleasant climate and unforgettable beauty-I knew if I ever got the opportunity,I would revisit this place.Twenty years went by until I was able to return to this city again.After emerging from the airport,I realized that I had grown older,while Xiamen was becoming increasingly youthful and vibrant.What exactly had given this city such vitality?
文摘BACKGROUND Malignant transformation(MT)of mature cystic teratoma(MCT)has a poor prognosis,especially in advanced cases.Concurrent chemoradiotherapy(CCRT)has an inhibitory effect on MT.CASE SUMMARY Herein,we present a case in which CCRT had a reduction effect preoperatively.A 73-year-old woman with pyelonephritis was referred to our hospital.Computed tomography revealed right hydronephrosis and a 6-cm pelvic mass.Endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)revealed squamous cell carci-noma.The patient was diagnosed with MT of MCT.Due to her poor general con-dition and renal malfunction,we selected CCRT,expecting fewer adverse effects.After CCRT,her performance status improved,and the tumor size was reduced;surgery was performed.Five months postoperatively,the patient developed dis-semination and lymph node metastases.Palliative chemotherapy was ineffective.She died 18 months after treatment initiation.CONCLUSION EUS-FNB was useful in the diagnosis of MT of MCT;CCRT suppressed the disea-se and improved quality of life.
文摘In this paper, we theoretically analyze the transformation of marketing strategy and the countermeasures under the network economic times. Network marketing is based on the network technology, including the whole process of marketing activities as a new form of marketing. In this paper, we analyze the issue from the listed perspectives. (1) Ultra space-and-time. The traditional marketing has very strong boundedness to the region, and this boundedness displays, the specifi c transaction can only be closed in the specific region, if the enterprise wants to expand the market share, only then establishes the retailing organization. (2) Interactivity. Network as a media, with the one-on-one interaction, this feature allows companies to basic communicate with consumers, and strengthen consumer participation, to determine the product form, function and the price. (3) The symmetry of information. Consumers can fi nd all kinds of that related products on the Internet information, there are plenty of time to judge the various products and prices. Companies will also be released in a timely manner on the Internet the company’s latest product information. Under this basis, we propose the new idea on the network marketing development direction that will help to build up the more efficient marketing system.
基金Supported by National Natural Science Foundation of China,No. 30973440 and No. 30770950key project of Chongqing Natural Science Foundation (CSTC,2008BA0021)
文摘AIM:To investigate the role of 64-slice computed tomography(CT) in portal vein cavernous transformation to determine surgical strategy.METHODS:The site of lesions and extent of collateral circulation in 12 pediatric cases of cavernous transformation of the portal vein with surgical treatment were analyzed.RESULTS:Eleven of 12 children had esophageal varices and were treated with lower esophageal and gastric devascularization and splenectomy,and the other case was only treated with splenectomy.There were eight cases with spontaneous spleen/stomach-renal shunt,four with Retzius vein opening,which was reserved during surgery.Three cases of lesions involving the intrahepatic portal vein(PV) were treated with living donor liver transplantation.One patient died from PV thrombosis after liver transplantation,and the rest had no significant complications.CONCLUSION:The PV,its branches and collateral circulation were clearly seen by 64-slice spiral CT angiography,which helped with preoperative surgical planning.
基金supported in part by the National Natural Science Foundation of China (No. 61803149 and No. 61977021)in part by the Technology Innovation Special Program of Hubei Province (No. 2020AEA008)in part by the Hubei Province Project of Key Research Institute of Humanities and Social Sciences at Universities (Research Center of Information Management for Performance Evaluation)
文摘Identity authentication is the first line of defense for network security.Passwords have been the most widely used authentication method in recent years.Although there are security risks in passwords,they will be the primary method in the future due to their simplicity and low cost.Considering the security and usability of passwords,we propose AvoidPwd,which is a novel mnemonic password generation strategy that is based on keyboard transformation.AvoidPwd helps users customize a“route”to bypass an“obstacle”and choose the characters on the“route”as the final password.The“obstacle”is a certain word using any language and the keys adjacent to the“obstacle”are typed with the“Shift”key.A two-part experiment was conducted to examine the memorability and security of the AvoidPwd strategy with other three password strategies and three leaked password sets.The results showed that the passwords generated by the AvoidPwd strategy were more secure than the other leaked password sets.Meanwhile,AvoidPwd outperformed the KbCg,SpIns,and Alphapwd in balancing security and usability.In addition,there are more symbols in the character distribution of AvoidPwd than the other strategies.AvoidPwd is hopeful to solve the security problem that people are difficult to remember symbols and they tend to input letters and digits when creating passwords.
基金We highly acknowledge the financial support of the Australian Centre for International Agricultural Research(ACIAR),Australia(ADP/2017/024)。
文摘Sustainable income growth and poverty reduction remain critical challenges at the forefront of research in Pakistan,particularly in rural areas.To overcome these challenges,the role of rural transformation(RT)has emerged and gained importance in recent years.The present study is based on district-level data and covers the period from 1981 to 2019.The study attempts to quantify the role of rural transformation in boosting rural per capita income and alleviating rural poverty in the country.The study also aims to explore the impact of stages of rural transformation on rural per capita income and rural poverty alleviation.The empirical findings reveal that rural transformation(RT_(1)and RT_(2))is essential in enhancing rural per capita income and alleviating rural poverty.The role of the share of high-value crops(RT_(1))is more pronounced than the share of non-farm employment(RT_(2))in boosting rural per capita income and poverty alleviation.The trend of larger contribution of RT_(1)to enhance rural per capita income also continued at 2nd stage of rural transformation.In the case of poverty reduction,at 3rd stage of rural transformation,the role of RT_(2)is dominant.Our results indicate that districts at higher stages of rural transformation(both RT_(1)and RT_(2))tend to correlate positively with increased rural per capita income and reduced poverty rates,suggesting that progress in rural transformation is associated with improved economic conditions.However,it is important to note that this correlation does not necessarily imply a direct causal relationship between rural transformation and these economic outcomes;other factors may have influenced this relationship.In addition,the welfare impacts are more noticeable among the districts where a simultaneous shift from grain crops to cash crops and from farm employment to non-farm employment is observed.The study provides baseline information to learn experiences from fast-growing districts and to replicate the strategies in other districts,which boosts the RT process that may increase rural per capita income and enhance poverty reduction efforts.
基金Supported by Science and Technology Support Program of Qiandongnan Prefecture,No.Qiandongnan Sci-Tech Support[2021]12Guizhou Province High-Level Innovative Talent Training Program,No.Qiannan Thousand Talents[2022]201701.
文摘BACKGROUND Intensive care unit-acquired weakness(ICU-AW)is a common complication that significantly impacts the patient's recovery process,even leading to adverse outcomes.Currently,there is a lack of effective preventive measures.AIM To identify significant risk factors for ICU-AW through iterative machine learning techniques and offer recommendations for its prevention and treatment.METHODS Patients were categorized into ICU-AW and non-ICU-AW groups on the 14th day post-ICU admission.Relevant data from the initial 14 d of ICU stay,such as age,comorbidities,sedative dosage,vasopressor dosage,duration of mechanical ventilation,length of ICU stay,and rehabilitation therapy,were gathered.The relationships between these variables and ICU-AW were examined.Utilizing iterative machine learning techniques,a multilayer perceptron neural network model was developed,and its predictive performance for ICU-AW was assessed using the receiver operating characteristic curve.RESULTS Within the ICU-AW group,age,duration of mechanical ventilation,lorazepam dosage,adrenaline dosage,and length of ICU stay were significantly higher than in the non-ICU-AW group.Additionally,sepsis,multiple organ dysfunction syndrome,hypoalbuminemia,acute heart failure,respiratory failure,acute kidney injury,anemia,stress-related gastrointestinal bleeding,shock,hypertension,coronary artery disease,malignant tumors,and rehabilitation therapy ratios were significantly higher in the ICU-AW group,demonstrating statistical significance.The most influential factors contributing to ICU-AW were identified as the length of ICU stay(100.0%)and the duration of mechanical ventilation(54.9%).The neural network model predicted ICU-AW with an area under the curve of 0.941,sensitivity of 92.2%,and specificity of 82.7%.CONCLUSION The main factors influencing ICU-AW are the length of ICU stay and the duration of mechanical ventilation.A primary preventive strategy,when feasible,involves minimizing both ICU stay and mechanical ventilation duration.
基金supported by the National Key Research and Development Projects,Nos.2022 YFC3602400,2022 YFC3602401(to JX)the Project Program of National Clinical Research Center for Geriatric Disorders(Xiangya Hospital),No.2020LNJJ16(to JX)the National Natural Science Foundation of China,No.82271369(to JX)。
文摘Hemorrhagic transformation is a major complication of large-artery atheroscle rotic stroke(a major ischemic stro ke subtype)that wo rsens outcomes and increases mortality.Disruption of the gut microbiota is an important feature of stroke,and some specific bacteria and bacterial metabolites may contribute to hemorrhagic transformation pathogenesis.We aimed to investigate the relationship between the gut microbiota and hemorrhagic transformation in largearte ry atheroscle rotic stro ke.An observational retrospective study was conducted.From May 2020 to September 2021,blood and fecal samples were obtained upon admission from 32 patients with first-ever acute ischemic stroke and not undergoing intravenous thrombolysis or endovascular thrombectomy,as well as 16 healthy controls.Patients with stro ke who developed hemorrhagic transfo rmation(n=15)were compared to those who did not develop hemorrhagic transformation(n=17)and with healthy controls.The gut microbiota was assessed through 16S ribosomal ribonucleic acid sequencing.We also examined key components of the lipopolysaccharide pathway:lipopolysaccharide,lipopolysaccharide-binding protein,and soluble CD14.We observed that bacterial diversity was decreased in both the hemorrhagic transformation and non-hemorrhagic transfo rmation group compared with the healthy controls.The patients with ischemic stro ke who developed hemorrhagic transfo rmation exhibited altered gut micro biota composition,in particular an increase in the relative abundance and dive rsity of members belonging to the Enterobacteriaceae family.Plasma lipopolysaccharide and lipopolysaccharide-binding protein levels were higher in the hemorrhagic transformation group compared with the non-hemorrhagic transfo rmation group.lipopolysaccharide,lipopolysaccharide-binding protein,and soluble CD14 concentrations were associated with increased abundance of Enterobacte riaceae.Next,the role of the gut microbiota in hemorrhagic transformation was evaluated using an experimental stroke rat model.In this model,transplantation of the gut microbiota from hemorrhagic transformation rats into the recipient rats triggered higher plasma levels of lipopolysaccharide,lipopolysaccharide-binding protein,and soluble CD14.Ta ken togethe r,our findings demonstrate a noticeable change in the gut microbiota and lipopolysaccharide-related inflammatory response in stroke patients with hemorrhagic transformation.This suggests that maintaining a balanced gut microbiota may be an important factor in preventing hemorrhagic transfo rmation after stro ke.
基金supported in part by the Strategic Priority Research Program of Chinese Academy of Sciences(XDA27030100)National Natural Science Foundation of China(72293575, 11832001)。
文摘The pursuit-evasion game models the strategic interaction among players, attracting attention in many realistic scenarios, such as missile guidance, unmanned aerial vehicles, and target defense. Existing studies mainly concentrate on the cooperative pursuit of multiple players in two-dimensional pursuit-evasion games. However, these approaches can hardly be applied to practical situations where players usually move in three-dimensional space with a three-degree-of-freedom control. In this paper,we make the first attempt to investigate the equilibrium strategy of the realistic pursuit-evasion game, in which the pursuer follows a three-degree-of-freedom control, and the evader moves freely. First, we describe the pursuer's three-degree-of-freedom control and the evader's relative coordinate. We then rigorously derive the equilibrium strategy by solving the retrogressive path equation according to the Hamilton-Jacobi-Bellman-Isaacs(HJBI) method, which divides the pursuit-evasion process into the navigation and acceleration phases. Besides, we analyze the maximum allowable speed for the pursuer to capture the evader successfully and provide the strategy with which the evader can escape when the pursuer's speed exceeds the threshold. We further conduct comparison tests with various unilateral deviations to verify that the proposed strategy forms a Nash equilibrium.
基金financially funded by Natural Science Basic Research Program of Shaanxi(grant number 2022JM-239)Key Research and Development Project of Shaanxi Provincial(grant number 2021LLRH-05–08)。
文摘To study the formation and transformation mechanism of long-period stacked ordered(LPSO)structures,a systematic atomic scale analysis was conducted for the structural evolution of long-period stacked ordered(LPSO)structures in the Mg-Gd-Y-Zn-Zr alloy annealed at 300℃~500℃.Various types of metastable LPSO building block clusters were found to exist in alloy structures at different temperatures,which precipitate during the solidification and homogenization process.The stability of Zn/Y clusters is explained by the first principles of density functional theory.The LPSO structure is distinguished by the arrangement of its different Zn/Y enriched LPSO structural units,which comprises local fcc stacking sequences upon a tightly packed plane.The presence of solute atoms causes local lattice distortion,thereby enabling the rearrangement of Mg atoms in the different configurations in the local lattice,and local HCP-FCC transitions occur between Mg and Zn atoms occupying the nearest neighbor positions.This finding indicates that LPSO structures can generate necessary Schockley partial dislocations on specific slip surfaces,providing direct evidence of the transition from 18R to 14H.Growth of the LPSO,devoid of any defects and non-coherent interfaces,was observed separately from other precipitated phases.As a result,the precipitation sequence of LPSO in the solidification stage was as follows:Zn/Ycluster+Mg layers→various metastable LPSO building block clusters→18R/24R LPSO;whereas the precipitation sequence of LPSO during homogenization treatment was observed to be as follows:18R LPSO→various metastable LPSO building block clusters→14H LPSO.Of these,14H LPSO was found to be the most thermodynamically stable structure.
基金supported by the National Natural Science Foundation of China (Grant No.71872122)Late-stage Subsidy Project of Humanities and Social Sciences of the Education Department of China (Grant No. 20JHQ095)
文摘The development of the existing building energy-saving transformation market is inseparable from the internal driving force of ESCO.Giving full play to the driving role of ESCO scientifically is the internal requirement to promote the healthy and orderly operation of the existing building energy-saving transformation market.This paper summarizes the practical experience of developing ESCO driving force operation in foreign existing building energy-saving transformation market,analyzes the bottleneck of developing ESCO driving force operation in China’s existing building energy-saving transformation market,and puts forward useful practical enlightenment based on the comparison between home and abroad;According to the optimization principle of ESCO driving force operation in the development of existing building energy-saving transformation market,the optimization design framework of ESCO driving force is proposed,and the implementation strategy of ESCO driving force optimization in the development of existing building energy-saving transformation market is planned.In order to optimize and improve the effectiveness of the operation and development of the energy-saving transformation market of existing buildings with the internal driving force of ESCO.
文摘The comprehensive pilot of China Telecom transformation was unveiled in Pudong of Shanghai a few days ago, which indicates comprehensive pilot projects starting formally. Huang WenLin, Vice President of China Telecom, attends the unveiling ceremony and proposes four requirements.
基金This research was financially supported by the Ministry of Trade,Industry,and Energy(MOTIE),Korea,under the“Project for Research and Development with Middle Markets Enterprises and DNA(Data,Network,AI)Universities”(AI-based Safety Assessment and Management System for Concrete Structures)(ReferenceNumber P0024559)supervised by theKorea Institute for Advancement of Technology(KIAT).
文摘Time-series data provide important information in many fields,and their processing and analysis have been the focus of much research.However,detecting anomalies is very difficult due to data imbalance,temporal dependence,and noise.Therefore,methodologies for data augmentation and conversion of time series data into images for analysis have been studied.This paper proposes a fault detection model that uses time series data augmentation and transformation to address the problems of data imbalance,temporal dependence,and robustness to noise.The method of data augmentation is set as the addition of noise.It involves adding Gaussian noise,with the noise level set to 0.002,to maximize the generalization performance of the model.In addition,we use the Markov Transition Field(MTF)method to effectively visualize the dynamic transitions of the data while converting the time series data into images.It enables the identification of patterns in time series data and assists in capturing the sequential dependencies of the data.For anomaly detection,the PatchCore model is applied to show excellent performance,and the detected anomaly areas are represented as heat maps.It allows for the detection of anomalies,and by applying an anomaly map to the original image,it is possible to capture the areas where anomalies occur.The performance evaluation shows that both F1-score and Accuracy are high when time series data is converted to images.Additionally,when processed as images rather than as time series data,there was a significant reduction in both the size of the data and the training time.The proposed method can provide an important springboard for research in the field of anomaly detection using time series data.Besides,it helps solve problems such as analyzing complex patterns in data lightweight.
基金supported by the National Key Research and Development Program of China(2021YFB3501002)State Key Program of National Natural Science Foundation of China(5203405)+3 种基金National Natural Science Foundation of China(51974220,52104383)National Key Research and Development Program of China(2021YFB3700902)Key Research and Development Program of Shaanxi Province(2020ZDLGY13-06,2017ZDXM-GY-037)Shaanxi Province National Science Fund for Distinguished Young Scholars(2022JC-24)。
文摘A large-scale fine-grained Mg-Gd-Y-Zn-Zr alloy plate with high strength and ductility was successfully prepared by multi-pass friction stir processing(MFSP)technology in this work.The structure of grains and long period stacking ordered(LPSO)phase were characterized,and the mechanical properties uniformity was investigated.Moreover,a quantitative relationship between the microstructure and tensile yield strength was established.The results showed that the grains in the processed zone(PZ)and interfacial zone(IZ)were refined from 50μm to 3μm and 4μm,respectively,and numerous original LPSO phases were broken.In IZ,some block-shaped 18R LPSO phases were transformed into needle-like 14H LPSO phases due to stacking faults and the short-range diffusion of solute atoms.The severe shear deformation in the form of kinetic energy caused profuse stacking fault to be generated and move rapidly,greatly increasing the transformation rate of LPSO phase.After MFSP,the ultimate tensile strength,yield strength and elongation to failure of the large-scale plate were 367 MPa,305 MPa and 18.0% respectively.Grain refinement and LPSO phase strengthening were the major strengthening mechanisms for the MFSP sample.In particularly,the strength of IZ was comparable to that of PZ because the strength contribution of the 14H LPSO phase offsets the lack of grain refinement strengthening in IZ.This result opposes the widely accepted notion that IZ is a weak region in MFSP-prepared large-scale fine-grained plate.
文摘Background: Cavernous transformation of the portal vein(CTPV) due to portal vein obstruction is a rare vascular anomaly defined as the formation of multiple collateral vessels in the hepatic hilum. This study aimed to investigate the imaging features of intrahepatic portal vein in adult patients with CTPV and establish the relationship between the manifestations of intrahepatic portal vein and the progression of CTPV. Methods: We retrospectively analyzed 14 CTPV patients in Beijing Tsinghua Changgung Hospital. All patients underwent both direct portal venography(DPV) and computed tomography angiography(CTA) to reveal the manifestations of the portal venous system. The vessels measured included the left portal vein(LPV), right portal vein(RPV), main portal vein(MPV) and the portal vein bifurcation(PVB). Results: Nine males and 5 females, with a median age of 40.5 years, were included in the study. No significant difference was found in the diameters of the LPV or RPV measured by DPV and CTA. The visualization in terms of LPV, RPV and PVB measured by DPV was higher than that by CTA. There was a significant association between LPV/RPV and PVB/MPV in term of visibility revealed with DPV( P = 0.01), while this association was not observed with CTA. According to the imaging features of the portal vein measured by DPV, CTPV was classified into three categories to facilitate the diagnosis and treatment. Conclusions: DPV was more accurate than CTA for revealing the course of the intrahepatic portal vein in patients with CTPV. The classification of CTPV, that originated from the imaging features of the portal vein revealed by DPV, may provide a new perspective for the diagnosis and treatment of CTPV.
文摘Digital transformation of education is an important strategic content of information construction in Chinese universities in recent years. Postgraduate education is characterized by many types of postgraduates, complex training links, long training process, and obvious individuation. Its information construction and digital transformation are the difficulties in the construction of smart campus in colleges and universities. This paper discusses the current situation and main problems of postgraduate education informatization in colleges and universities, and puts forward the key points and suggestions of digital transformation of postgraduate education in colleges and universities from the aspects of optimizing the information platform of postgraduate education management and service, driving the modernization and wisdom of postgraduate education with data, constructing the integrated platform of intelligent teaching, and continuously improving the digital literacy of teachers and students.
文摘During the Cold War,the United States implemented an"offshore balance"policy in the Middle East,on the one hand,competing with the Soviet Union for a sphere of influence,and on the other hand,not directly engaging in the war.After the end of the Cold War,the US,as the sole super power,switched to the strategy of direct intervention in the Middle East.
文摘Since the emergence of COVID-19 in 2020,the threaten of emerging infectious diseases(EIDs)has attracted great attentions and echoes either from professional institutions,governments or public.The conceptualization of“Disease X”,which covers more than 30 families of viruses,has strongly actuated various resources into the development of medical countermeasures and the research across all families of pathogens.On the other hand,the endemic even pandemic old communicable diseases,such as tuberculosis(TB),malaria,HIV/AIDS,etc.,should never be neglected.Globally in 2023,the estimated TB cases was 10.8 million and the estimated deaths was 1.25 million according to the Global Tuberculosis Report 2024 by World Health Organization(WHO)[1].The most affected countries are India,Indonesia,China,the Philippines,Pakistan,Nigeria,Bangladesh,and the Democratic Republic of the Congo.
基金supported by CAMS Innovation Fund for Medical Sciences(CIFMS,2021-I2M-C&TB-030).
文摘It is well-known that elevated low-density lipoprotein cholesterol(LDL-C)is a causal risk factor for atheroscler-otic cardiovascular disease(ASCVD),statins are cornerstone drugs for the cause-based treatment of ASCVD,which has created a new era for ASCVD therapy.However,statin intolerance is not clinically uncommon,which there are several issues with confu-sion and misunderstandings.Hence,a file named Chinese Expert Consensus on the Diagnosis and Management Strategy of Pa-tients With Statin Intolerance,like a navigator,has recently been published written by a team of experts from the Cardiovascular Metabolic Medicine Professional Committee,Expert Committee of the National Center for Cardiovascular Diseases aiming to en-hance the standardized clinical application of statins and improve the prevention and clinical outcome.In this article,author briefly summarized the key points of above consensus in order to helping to comprehending the content of the consensus sugges-tions.