Treating acute low back pain with acupuncture:A randomized controlled study protocol to compare the effectiveness between distal and local acupoints

Objective:To compare the efficacy of using“distal acupoints only”vs.“local acupoints mainly combined with distal acupoints”in cases of acute low back pain(ALBP).Methods: A total of 102 eligible patients aged 18–65 years with ALBP lasting less than 6 weeks will be randomized in a 1:1 ratio to the distal acupoints only group(DPOG)and the local acupoints mainly combined with the distal acupoints group(LPMG).During a 4-week treatment period,patients in the DPOG will receive acupuncture at distal acupoints only(Houxi[SI 3]and Yaotongxue[EX-UE 7])twice a week,while those in the LPMG group will receive acupuncture at local acupoints(mainly Shenshu[BL 23]and Dachangshu[BL 25])combined with distal points(Weizhong[BL 40]).The patients in both groups will be evaluated at every session of treatment,and the follow-up will be performed for 3 months.The primary outcome measure will be the change in ALBP intensity,assessed using visual analogue scale scores before and after treatment.The secondary outcome measure will be the evaluation of functional disability using the Oswestry Disability Index.Discussion: This study compares the DPOG and LPMG to explore the feasibility of the DPOG in the treatment of ALBP.

Analysis of the Effect of Transcutaneous Electrical Stimulation of Acupoints Combined with Rehabilitation Training in The Treatment of Upper Limb Dysfunction After Stroke

Objective:To analyze the effect of combining transcutaneous electrical acupoint stimulation(TEAS)with rehabilitation training in patients with upper limb dysfunction after stroke(ULDAS).Methods:A total of 130 ULDAS patients who were hospitalized and rehabilitated in Wuxi Xinwu District Rehabilitation Hospital from May 2021 to May 2023 were selected and randomly divided into Group A(65 cases,rehabilitation training)and Group B(65 cases,rehabilitation training+TEAS).The effects of the two groups were compared.Results:After treatment,the upper limb functional indexes of Group B were better than those of Group A(P<0.05).The rate of muscle tone grades 0-4 in Group B was higher than those of Group A(P<0.05).Conclusion:The function of upper limbs and muscle strength of ULDAS patients improved by combining TEAS with rehabilitation training.

Analysis of the Effect of Traditional Chinese Medicine Nursing Intervention Combined with Acupoint Application in The Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Objective:To study the effect of Traditional Chinese medicine(TCM)nursing intervention combined with acupoint patch in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods:A total of 60 patients with acute exacerbation of COPD admitted between September 2022 and September 2023 were selected and randomly grouped into a control group(conventional care and treatment)and an observation group(joint interventions:traditional Chinese medicine nursing interventions,acupoint compresses),with 30 patients each.The arterial blood gas indexes of the two groups,hospitalization time,pulmonary function indexes,and TCM symptom scores were analyzed and compared between the two groups.Results:The arterial oxygen pressure(PaO_(2))(9.52±1.02 kPa)and partial pressure of carbon dioxide(PaCO_(2))(5.01±1.02 kPa)of the observation group were better than those of the control group after the intervention(P<0.05).The forced expiratory volume(FEV1)(3.38±0.15%),the FEV1% prediction value(72.52±2.25),and the FEV1/forced vital capacity(FVC)(79.52±1.41%)were higher than those of the control group(P<0.05).The hospitalization time(12.16±1.02 d)and TCM symptom score(4.12±1.26)of the observation group were better than those of the control group(P<0.05).Conclusion:Significant nursing effects were achieved by carrying out combined interventions(Chinese medicine nursing intervention and acupoint application)during the acute exacerbation of COPD.

Efficacy of acupoint injection in the treatment of chronic eczema and its influence on peripheral blood T cells

BACKGROUND Chronic eczema significantly impacts daily life,social interactions,and quality of life;however,no curative treatment has been identified.AIM To determine the clinical efficacy of acupoint injection for chronic eczema and its influence on peripheral blood T cells.METHODS Eighty patients with chronic eczema treated at our hospital between June 2022 and March 2023 were randomly assigned to a control group(n=40),which received conventional Western medicine treatment,or an observation group(n=40),which received routine Western medicine treatment plus acupoint injection of triamcinolone acetonide.Response and adverse reaction rates,as well as differences in the levels of serum cytokines IFN-γ,IL-2,IL-4,and IL-10 before and after treatment were investigated.RESULTS No difference in overall response rates were found between the observation and control groups(100%vs 90%,respectively;P>0.05);however,the observation group had a higher marked response rate than the control group(87.5%vs 52.5%;P<0.05).Both groups had decreased Eczema Area and Severity Index scores and increased pruritus after treatment(P<0.05),particularly in the observation group(P<0.05).The observation group had an adverse reaction rate of 2.5%(1/40),which did not differ significantly from that of the control group(P>0.05).The observation group exhibited higher post-treatment INF-γand IL-2 but lower IL-4 levels than the control group(P<0.05);however,no significant inter-group difference was observed in post-treatment IL-10 levels(P>0.05).CONCLUSION Acupoint injection of triamcinolone acetonide is safe and effective in treating chronic eczema.Its therapeutic mechanism is related to the regulation of peripheral blood T cell levels,inhibition of inflammatory reactions,and mitigation of immune imbalance.

Mechanism of acupoint penetration acupuncture therapy regulating chondrocyte autophagy via the PI3K/Akt-mTOR pathway in KOA rats

Objective:To investigate whether acupoint penetration acupuncture(APA)could regulate chondrocyte autophagy and apoptosis via the PI3K/Akt-mTOR signaling pathway to reduce cartilage degeneration in knee osteoarthritis(KOA)rats.Methods: KOA was induced in rats via intra-articular injection of sodium iodoacetate resolution.Forty male Sprague-Dawley rats were randomly assigned to blank control,model,APA,electro-acupuncture(EA),and sham model groups(n=8)and those in the APA and EA groups received their respective therapies.Following completion of the treatment course,histological examinations of cartilage and muscle were conducted.Levels of apoptosis-and autophagy-related factors,including Bax,Bcl-2,mTOR,ULK-1,and Beclin-1 protein,and mRNAs were assessed.Additionally,β-endorphin(β-EP)concentrations in the brain and serum were measured.Results: Histological analysis revealed that APA alleviated cartilage and muscle damage compared with the model group.APA inhibited cartilage degeneration by modulating the expression of apoptosis-and autophagy-related proteins and mRNA,thus preventing chondrocyte apoptosis.In the APA group,Bax and mTOR protein levels were significantly lower than those in the model group(both P=.024).Conversely,the Bcl-2 expression level was significantly higher than that in the EA group(P=.035).Additionally,ULK-1 expression was significantly lower than that in the EA group(P=.045).The mRNA level of Bax was significantly higher than that in the blank control group(P<.001).However,Beclin-1 levels were significantly higher than those in both the model and EA groups(both P<.001).ELISA results showed a significant decrease in the concentration ofβ-EP in the brains of the rats in the APA group compared with those in the model group(P=.032).Conclusions: APA reduced osteoarthritis-related pain and alleviated cartilage damage by upregulating chondrocyte autophagy and down-regulating apoptosis via signaling pathways involving PI3K/Akt-mTOR in KOA rats.

Analysis of acupoint massage combined with touch on relieving anxiety and pain in patients with oral implant surgery

BACKGROUND Oral implant surgery is an effective procedure for artificial implants in missing tooth areas under local anesthesia.Because patients under local anesthesia are conscious during this procedure,compared with general anesthesia-related operations,they are more likely to experience negative emotions,such as anxiety and tension.These emotional reactions result in shivering and chills in the limbs,leading to poor doctor-patient cooperation and even avoidance of treatment.In traditional Chinese medicine,it is believed that acupoint massage regulates blood and Qi,dredge menstruation,and relieve pain,which is beneficial for patients’emotional adjustment;however,there are few related clinical studies.AIM To observe the changes in anxiety and pain in patients with oral implant after acupoint massage combined with touch therapy.METHODS One hundred patients undergoing oral implantation in our hospital between May 2020 and May 2023 were randomly divided into control and study groups,according to a random number table,with 50 patients in each group.The control group received routine intervention,and the study group received acupoint massage combined with touch on the basis of the control group.Anxiety[assessed using the Modified Dental Anxiety Scale(MDAS)],pain severity,blood pressure,heart rate,and satisfaction were compared between the two groups.RESULTS Before intervention,the difference in MDAS score between the two groups was not significant(P>0.05),while after the intervention,the MDAS scores decreased in both groups compared with those before the intervention(P<0.05);the MDAS score of the study group was lower than that of the control group,with a statistically significant difference(P<0.05).The degree of pain in the intervention group was significantly lower than that in the control group(P<0.05).Before the intervention,there were no significant differences in systolic and diastolic blood pressures or heart rate between the two groups(P>0.05).The systolic and diastolic blood pressures and heart rate in the intervention group,during and after the intervention,were significantly lower than those in the control group(P<0.05).The total degree of satisfaction in the study group was significantly higher than that in the control group(P<0.05).CONCLUSION Acupoint massage combined with touch better relieves anxiety and pain in patients undergoing dental implant surgery,improving the perioperative comfort of these patients and ensuring safety and a smooth operation.

Acupoint catgut-embedding therapy ameliorates DNCB-induced atopic dermatitis in BALB/c mice by regulating Th2 type immune response and reducing infiltration of CD4^(+)and CD8^(+)cells

Background:This study aimed to assess how acupoint catgut-embedding therapy influences Th2-type immune response and the infiltration of CD4^(+)and CD8^(+)cells in DNCB-induced atopic dermatitis in BALB/c mice.It also conducted an initial examination of the underlying molecular mechanisms.Methods:Seventy-two mice were randomly divided into four groups:normal control,DNCB-induced atopic dermatitis model(AD),AD with acupoint catgut-embedding treatment(ADA),and AD with sham-acupoint catgut-embedding treatment.After DNCB challenge to induce AD,the ADA group received acupoint catgut-embedding therapy treatment at Zusanli(ST 36)and Quchi(LI 11)acupoints every other week from day 8.Mice in the AD with sham-acupoint catgut-embedding treatment group underwent the same procedure as the ADA group but without catgut implantation.Severity was assessed using SCORAD on treatment days 1,10,and 20.On day 18,nine mice per group were euthanized,and the remaining on day 28.Histopathological changes were observed using hematoxylin-eosin and immunohistochemistry staining.TNF-α,IL-4,IL-6,and IL-13 levels were analyzed by ELISA,and GATA3 and STAT6 protein levels by western blot.Results:After 20 days of acupoint catgut-embedding therapy treatment,mice showed reduced dermatitis scores compared to DNCB-induced AD-like mice.Significant decreases occurred in serum IL-4,IL-6,IL-13,and TNF-αlevels.Skin analysis revealed marked reductions in CD4^(+)and CD8^(+)cell infiltration,as well as GATA3 and STAT6 protein levels.Conclusion:Acupoint catgut-embedding therapy may effectively alleviate atopic dermatitis by suppressing Th2 immune responses via the STAT6-GATA3 pathway and reducing CD4^(+)and CD8^(+)T cell infiltration in skin lesions.

Exploring the mechanism of electroacupuncture at different acupoints on acute colitis rats based on JAK2/STAT3/SOCS1 signaling pathway

Objective:To investigate the mechanism of JAK2/STAT3/SOCS1 signaling pathway in electroacupuncture of different acupoints on acute colitis rats.Methods:36 SPF SD rats were randomly divided into 6 groups,with 6 rats in each group.The rat model of acute colitis was prepared by enema with glacial acetic acid solution.After the model was established,electroacupuncture was given to each acupoint group,with density wave,frequency 2Hz-50 Hz,intensity 2 mA,muscle tremor as the degree 20 min/time,1 time/day,for 3 consecutive days.Observe the general condition of rats;the pathological changes of colonic mucosa in rats were observed by HE method.The contents of serum interleukin-4(IL-4)and interleukin-8(IL-8)were detected by ELISA.Western blot and RT-PCR were used to detect the expression of JAK2,STAT3,SOCS1 protein and mRNA in rat colon tissue.Results:In contrast to the normal group,the overall condition of the model group was worse,the colonic mucosa was severely damaged,even necrotic,and the ulcer surface was obvious.The content of IL-4 in serum was obviously reduced,and the content of IL-8 was obviously go up(P<0.01).The protein content of JAK2,STAT3 and the expression of JAK2,STAT3 mRNA in colon tissue of rats were obviously go up,while the protein content of SOCS1 and the expression of SOCS1 mRNA were obviously reduced(P<0.01).In contrast to the model group,the general condition of rats in each acupoint group was significantly improved,the damage and necrosis of colonic mucosa and ulcer surface were obviously alleviated,the content of IL-4 in serum was obviously go up,and the content of IL-8 was significantly decreased(P<0.01).The protein content of JAK2,STAT3 and the expression of JAK2,STAT3 mRNA in colon tissue of rats were obviously reduced,while the protein content of SOCS1 and the expression of SOCS1 mRNA were obviously go up(P<0.05,P<0.01).Comparison of different acupoint groups,the colonic mucosal injury in the Zusanli group was significantly reduced,the content of serum IL-4 was significantly increased,and the content of IL-8 was significantly decreased(P<0.05,P<0.01).The protein content and mRNA expression of JAK2 and STAT3 in colon tissue were significantly down-regulated,while the protein content and mRNA expression of SOCS1 were significantly go up(P<0.05,P<0.01).Conclusion:Electroacupuncture at each acupoint can improve the damage of colonic mucosa and reduce the inflammatory response.The therapeutic effect of Zusanli(ST36)is better than that of Tianshu(ST25),Dachangshu(BL25)and Shangjuxu(ST37).The mechanism may be related to the regulation of JAK2/STAT3/SOCS1 signaling pathway related proteins and inflammatory cytokines IL-4 and IL-8.

Clinical Study on the Therapeutic Effect of Combined Traditional Chinese Medicine with Acupoint Injection and Herbal Paste Application in Treating Ovulatory Dysfunction in Polycystic Ovary Syndrome (PCOS)

Objective: To observe the therapeutic effect of combined traditional Chinese medicine (TCM) therapy with acupoint injection and herbal patch application on patients with ovulatory dysfunction associated with polycystic ovary syndrome (PCOS). Methods: A total of 80 PCOS patients who received treatment at the First Affiliated Hospital of Guangxi University of Chinese Medicine between October 2022 and March 2024 were enrolled in this study. They were randomly divided into a control group (n = 40) and an observation group (n = 40). The control group received conventional Western medical treatments, while the observation group was administered TCM combined with acupoint injection and herbal patch application. Pre- and post-treatment conditions were compared between the two groups. Results: After treatment, the overall effective rate was significantly higher in the observation group compared to the control group (P 0.05). Following treatment, both ovulation and pregnancy rates increased in both groups, but the increase was more evident in the observation group, showing a statistically significant difference (P < 0.01). Conclusion: For patients with oligoovulation or anovulation due to PCOS, the combined use of TCM, acupoint injection, and herbal patch application appears to be effective in improving systemic symptoms and achieving notable clinical outcomes.

Effect of Acupoint Liquid Nitrogen Cryotherapy on Neuro-Endocrine-Immune Network System in Patients with Lung Qi Deficiency Syndrome in Remission Stage of Bronchial Asthma

[Objectives]To observe the effect of acupoint liquid nitrogen cryotherapy on the neuro-endocrine-immune network system of lung qi deficiency syndrome during the remission period of bronchial asthma and explore its possible mechanism.[Methods]A total of 100 patients with bronchial asthma were randomly divided into control group and observation group,with 50 cases in each group.The control group was given budesonide spray inhalation treatment,combined with acupoint liquid nitrogen freezing treatment,twice a year for a course of treatment,followed up for 1 year.The other 50 healthy volunteers were included in the healthy group,and no treatment was given in the healthy group.Serum immunoglobulins A,G,E(IgA,IgG,IgE)were detected before and after treatment in each group,serum cytokines[interleukin-4(IL-4),interleukin-10(IL-10),tumor necrosis factor-α(TNF-α),interferon-γ(IFN-γ)],plasma neurotransmitters[substance P(SP),vasoactive intestinal peptide(VIP)].[Results]Before treatment,compared with healthy group,the contents of IgA,IgG,IL-10,IFN-γand VIP in observation group and control group were decreased,while the contents of IgE,IL-4,TNF-αand SP were increased,with statistical significance(P<0.05).After treatment,compared with before treatment,IgA,IgG,IL-10,IFN-γand VIP contents in observation group and control group were increased(P<0.05),and observation group was higher than control group(P<0.05),IgE,IL-4 and SP contents in observation group and control group were decreased(P<0.05).The observation group was lower than the control group(P<0.05).[Conclusions]Acupoint liquid nitrogen cryotherapy may improve the immune function of the body,regulate the release of cytokines and regulate neuromediators,and thus play a role in the prevention and treatment of bronchial asthma.

Effect of Head Meridian Massage Combined with Auricular Acupoint Plaster on Patients with Insomnia

Objective:To study the effect of head meridian massage combined with auricular acupoint plasters on patients with insomnia.Methods:The sample consisted of 50 cases,and all of them were admitted to Yixing Hospital of Traditional Chinese Medicine from January 2022 to December 2023.The patients were divided into an observation group and a control group,with 25 cases in each group.The observation group was treated with a combination of head meridian massage and auricular acupoint plaster while the control group underwent conventional nursing care.The improvement of sleep quality and nursing effect were used as evaluation criteria to compare the clinical effects of the nursing programs.Results:After nursing intervention,the Pittsburgh sleep quality index(PSQI)score of the observation group,which was 7.17±1.41 points was lower than that of the control group(9.04±1.96 points),(t=3.8724,P<0.05).The total efficacy was 96.00%for the observation group and 76.00%for the control group(2=4.1528,P<0.05).Conclusion:Head meridian massage combined with auricular acupoint can improve the sleep quality of patients with insomnia.

Clinical Analysis of Acupuncture Combined with Acupoint Injection for the Treatment of Chronic Nonbacterial Prostatitis

Objective:To evaluate the therapeutic effect of acupuncture combined with acupoint injection on chronic nonbacterial prostatitis(CNP).Methods:A total of 72 CNP patients admitted between March 2022 and October 2023 were selected.The patients were randomly divided into two groups using a random number table.The combined treatment group(36 cases)received acupuncture combined with acupoint injection therapy,while the control group(36 cases)received conventional Western medicine treatment.The overall efficacy rate,symptom severity,prostatic fluid indicators,incidence of adverse reactions,and recurrence rates were compared.Results:The overall efficacy rate of the combined treatment group was higher than that of the control group(P<0.05).After 10 days of treatment,the symptom severity score of the combined treatment group was higher than that of the control group,and the prostatic fluid indicators were lower than those of the control group(P<0.05).The incidence of adverse reactions in the combined treatment group was lower than in the control group(P<0.05).During the follow-up period of 1-6 months,the recurrence rate in the combined treatment group was lower than that in the control group(P<0.05).Conclusion:Acupuncture combined with acupoint injection can alleviate CNP disease symptoms,improve prostate function,and prevent post-treatment adverse reactions.It also has a lower recurrence risk and demonstrates excellent efficacy.

Evaluation of the Efficacy of Auricular Acupoint Pressure Patch Combined with Modified Huangqi Decoction in Treating Diabetic Nephropathy

Objective:To explore the efficacy of auricular acupoint pressure patch combined with modified Huangqi Decoction in treating diabetic nephropathy.Methods:60 patients with diabetic nephropathy treated in our hospital from January 2021 to December 2022 were selected for this study.The patients were randomly divided into two groups using the random number table method,with 30 patients in each group.Among them,the control group was treated with conventional Western medicine,while the experimental group was treated with auricular acupoint pressure patches combined with modified Huangqi Decoction.The patients’fasting blood glucose(FPG),2-hour postprandial blood glucose(2hPG),glycated hemoglobin(HbA1c),urinary protein quantification,urea nitrogen(BUN),serum creatinine(SCr),and other indicators were detected and recorded before and after treatment.Results:Before treatment,there was no statistically significant difference in the FPG,the 2hPG,and the HbA1c between the two groups of patients(P>0.05);after treatment,the FPG,the 2hPG,and the HbA1c of the patients in the experimental group were significantly lower than those in the control group(P<0.05).Before treatment,there was no statistically significant difference in the urinary protein quantification,the BUN,and the SCr between the two groups of patients(P>0.05);after treatment,the urinary protein quantification,BUN,and SCr of the patients in the experimental group were significantly lower than those in the control group(P<0.05).The experimental group showed better improvement in symptoms such as fatigue,backache,and frequency of nocturia(P<0.05).Conclusion:Auricular acupoint pressure patch combined with modified Huangqi Decoction effectively treats diabetic nephropathy and it helps control blood sugar and renal function indicators and improve clinical symptoms,therefore improving the patients’quality of life.

腔内腧穴理论和实践初探

针灸学理论认为,腧穴位于体表,具有诊断与治疗的双重作用。基于临床,发现“气管隆脊”具有与体表腧穴相似的诊断与治疗的双重作用;因此提出“腔内腧穴”与“腔内(介入)针灸学”的概念。该假说有待进一步临床验证与理论构建。

水稻精准穴播机关键技术研究

为提高水稻穴播机的精准穴播效率,该文研究了一种多环节种群分离、组穴系统,包括种群自流动分离机构,轨道振动规整、排序及组穴机构,该机构使种群近似自然流动状态,种群分离、组穴过程对芽种无挤压和剪切破坏作用。利用高速CCD摄像机成像技术,对检测通道内种粒下落分布状态进行分析,并与传感器检测结果进行对比,为执行机构“一次组穴”修正方案提供理论依据。采用高密度穴孔的储穴-排种双盘轮播结构来降低其旋转速度,配合采用“近地点播种”控制策略,提高同穴种粒落地一致性,同时研究了双盘轮播机构的护种和换向控制策略。通过以上设计提高了穴粒合格率和成穴性能,降低种子的破损率。

通腑饮灌肠联合新斯的明足三里穴位注射治疗腹内高压临床观察

目的探讨通腑饮灌肠联合新斯的明足三里穴位注射治疗腹内高压(IAH)的临床疗效。方法选取医院重症医学科2019年10月至2022年6月收治的IAH患者85例,按随机数字表法分为A组(常规治疗,21例),B组(常规治疗+通腑饮灌肠,18例),C组(常规治疗+新斯的明足三里穴位注射,25例),D组(常规治疗+通腑饮灌肠+新斯的明足三里穴位注射,21例)。结果4组患者的肠鸣音次数、腹内压、D-乳酸、二胺氧化酶存在时间与组间的交互效应差异显著(F组间=5.963,15.380,10.964,9.671,P=0.001,0.001,0.001,0.001)。治疗后第3,5,7天,D组患者的肠鸣音次数显著多于A组(P<0.05);腹内压、D-乳酸、二胺氧化酶显著低于A组、B组、C组(P<0.05);启动肠内营养时间均显著早于A组、B组、C组(P<0.05);机械通气时间、重症监护室(ICU)住院时间显著短于A组、B组、C组(P<0.001)。4组患者的死亡(放弃)率相当(14.29%比11.11%比12.00%比9.52%,P=0.100)。4组患者均未发生不良反应。结论通腑饮灌肠联合新斯的明足三里穴位注射治疗IAH,可改善患者的胃肠道血液循环,保护肠道屏障功能,缩短肠内营养启动时间、机械通气时间及ICU住院时间,且安全性良好。

化瘀利水方穴位贴敷联合西药治疗癌性腹水

目的:观察化瘀利水方穴位贴敷联合西药治疗恶性肿瘤Ⅲ、Ⅳ期癌性腹水(水瘀互结证)患者的临床疗效。方法:80例水瘀互结型癌性腹水患者按照随机数字表法分为观察组和对照组各40例。对照组给予西医基础治疗,观察组在对照组治疗基础上给予化瘀利水方神阙穴贴敷治疗。两组均连续治疗14 d。比较两组患者治疗前后中医证候积分、Karnofsky功能状态(KPS)评分、腹水消退疗效、体质量、腹围、24小时尿量等。结果:(1)腹水消退疗效比较:治疗后,观察组显效12例,稳定22例;对照组显效5例,稳定21例;观察组有效率为85.0%(34/40),高于对照组的65.0%(26/40),差异有统计学意义(P<0.05)。(2)中医证候积分、体质量、腹围、24小时尿量比较:治疗后,两组患者中医证候积分、体质量、腹围均低于本组治疗前,24小时尿量均高于本组治疗前;观察组中医证候积分(5.85±2.78)分、体质量(54.25±7.65)kg、腹围(90.79±2.34)cm均低于同期对照组(P<0.05),24小时尿量[1452.55(1304.20,1519.48)]mL高于同期对照组(P<0.05)。(3)KPS评分比较:治疗后,观察组提高12例,稳定21例;对照组提高6例,稳定20例;观察组改善率为82.5%(33/40),高于对照组的65.0%(26/40),差异有统计学意义(P<0.05)。结论:化瘀利水方穴位贴敷联合西药治疗癌性腹水(水瘀互结证)临床疗效显著,可明显提高患者生活质量,改善患者临床症状。

基于R语言数据挖掘技术的针灸治疗带状疱疹后遗神经痛选穴规律研究

目的应用R语言数据挖掘技术分析针灸治疗带状疱疹后遗神经痛(PHN)的选穴规律。方法检索中国知识资源总库(CNKI)、万方数据知识服务平台(万方数据)、维普中文期刊服务平台(维普网)、中国生物医学文献数据库(CBM)2010年1月1日-2023年7月1日收录的针灸治疗PHN的临床研究文献,利用Excel2016建立数据库,采用R语言对腧穴使用频次、归经、部位、特定穴等进行统计,并进行关联规则分析和聚类分析,得出针灸治疗PHN的选穴特点及规律。结果共纳入198篇文献,包含83个腧穴,总频次为714。高频腧穴为阿是穴、夹脊穴、阳陵泉等,常用经脉为足少阳胆经、足太阴脾经和手阳明大肠经,腧穴多分布于上下肢部,以五输穴、原穴和下合穴居多。核心腧穴为阿是穴、夹脊穴、合谷、曲池,并得到9组关联规则和5个有效聚类。结论针灸治疗带状疱疹后遗神经痛的核心腧穴为阿是穴、夹脊穴、合谷、曲池,主要遵循局部取穴与远端取穴相结合的选穴原则。

“以痛为腧”推拿对膝骨关节炎患者步态及足底压力的影响研究

目的观察“以痛为腧”推拿手法对膝骨关节炎(knee osteoarthritis,KOA)患者步态及足底压力平衡分布的影响。方法选取2023年3月—2023年10月上海中医药大学附属岳阳中西医结合医院推拿科就诊的KOA患者50例,将其随机分为观察组和对照组,各25例。观察组给予推拿干预,对照组给予宣教干预。对比2组干预前后西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分、步态相关参数(步速、步幅、步长、双侧支撑相、单支撑相)及足底压力。结果2组均未出现严重安全问题及不良事件,50例患者均完成研究。干预后,观察组WOMAC总分、疼痛评分、活动程度评分均较干预前降低,且低于对照组干预后(P<0.05)。观察组干预前后僵硬评分比较差异无统计学意义(P>0.05)。干预后,观察组步速、步幅、双侧支撑相、单支撑相均较干预前改善,且优于对照组(P<0.05)。观察组干预前后步长比较差异无统计学意义(P>0.05)。干预后,观察组前足内部区压力较干预前升高,且高于对照组(P<0.05)。观察组干预前后其他区压力比较差异无统计学意义(P>0.05)。结论基于“以痛为腧”推拿能显著提高患者的步行能力及前足内部压力,有助于恢复步态的稳定性。

体外受精-胚胎移植的针灸辅助治疗策略

本文基于全国名中医尤昭玲中医全病程管理辅助体外受精-胚胎移植(IVF-ET)的“二段四期三法”辨治理念,从理、法、方、穴、术5个方面探析针灸辅助的治疗策略。理:辨证审因,随案调治;法:依理取法,阶段诊治;方:依法定方,整体调治;穴:精准取穴,配伍同治;术:针刺为主,多法施治,为临床运用针灸辅助IVF-ET提供思路和参考依据。