Objective:To examine and compare the synchronization of different brain regions during the Chinese and English Stroop tasks.Methods.Ten native Chinese speakers with a moderate command of English participated in this s...Objective:To examine and compare the synchronization of different brain regions during the Chinese and English Stroop tasks.Methods.Ten native Chinese speakers with a moderate command of English participated in this study,and event-related potentials were recorded while participants performed the Stroop task.Then wavelet-based estimation of instantaneous EEG coherence was applied to investigate the synchronization of different brain regions during Stroop task.Results:A greater negativity for the in- congruent situation than congruent situation appeared from 350ms to 600ms post-stimulus onset over frontal,central,and parietal regions in Chinese Stroop task,while the negativity was absent in English Stroop task.However,not only in Chinese Stroop task but also in English Stroop task was it found signif- icantly higher EEG coherences for the incongruent situation than congruent situation over frontal,pari- etal,and frontoparietal regions before 400ms post stimulus onset atβ(13-30 Hz) frequency band.Conclu- sion:This finding indicated that wavelet-based coherence is more exquisite tool to analyze brain electro- physiological signals associated with complex cognitive task than ERP component,and that functional syn- chronization indexed by EEG coherence is enhanced at the earlier stage while processing the conflicting in- formation for the incongruent stimulus.展开更多
Background The etiology and pathology of functional constipation (FC) is unclear.Some researches suggest that psychological factors may be related to this common problem.This study aimed to investigate the relations...Background The etiology and pathology of functional constipation (FC) is unclear.Some researches suggest that psychological factors may be related to this common problem.This study aimed to investigate the relationship between attention processing and emotional status in FC patients compared with healthy controls.Methods We investigated selective attention and emotional status in patients with FC using the counting Stroop task.Thirty-five FC patients (FCP group) and 24 healthy controls (HCs) underwent an event-related potential (ERP) study while performing the task.Response time,latency and amplitude of P300 were collected and compared between the two groups.The Hamilton Depression Rating Scale (HAMD-17),Hamilton Anxiety Scale (HAMA),Symptom Checklist-90 (SCL-90) and Eysenck Personality Questionnaire (EPQ) were administered prior to the counting Stroop task.Results Scores for the FCP group differed significantly from those for the HCs on the HAMD-17,HAMA,SCL-90 (Global Severity Index,Positive Symptoms Total,dimensions of somatization,obsessive-compulsive,depression,anxiety,and psychosis),as well as extraversion and neurosis dimensions of the EPQ (P〈0.05).There was no significant difference in response time or accuracy rate between the two groups (P〉0.05).ERP results showed prolonged latency at F4,additionally found enhanced activation at F3,FC1 and T8,and decreased activation at sites FC6 and P7 in the patients with FC.Statistically,significant differences of P300 latency at site F4 (P 〈0.05) and P300 amplitude at F3,F4,T8,P7,FC1 and FC6 (P〈0.05) between the patients with FC and the HC were revealed.Conclusions The findings suggest that patients with FC are more susceptible to depression and anxiety,as well as somatization,obsessive-compulsive tendencies and other neurotic personality characteristics.Patients may employ psychological defense mechanisms to avoid the pain of depression and anxiety.ERP results imply there may be some brain dysfunction and attention deficits in patients with FC.展开更多
Light modulates human brain function through its effect on circadian rhythms,which are related to several human behavioral and physiological processes.Functional near-infrared spectroscopy(fNIRS)is a noninvasive optic...Light modulates human brain function through its effect on circadian rhythms,which are related to several human behavioral and physiological processes.Functional near-infrared spectroscopy(fNIRS)is a noninvasive optical neuroimaging technique used for recording brain activation during task performance.This study aimed to investigate the effects of light on cognitive function,particularly in the prefrontal cortex using fNIRS.The effect of light on cognitive modulation was analyzed using the Stroop task,which was performed on 30 participants under three different light conditions(color temperature 4500 K,2500 K,and none).The behavioral results indicated that light conditions can easily and effectively modulate the performance of tasks based on the feedback,including the response time and accuracy.fNIRS showed hemodynamic changes in the bilateral dorsolateral prefrontal cortices,and the activated brain regions varied under different light conditions.Moreover,light may be regarded as a safe,effective,inexpensive,and accessible tool for modulating human cognitive function.展开更多
基金Supported by the National Natural Science Foundation of China(No. 60375037 and 60543003).
文摘Objective:To examine and compare the synchronization of different brain regions during the Chinese and English Stroop tasks.Methods.Ten native Chinese speakers with a moderate command of English participated in this study,and event-related potentials were recorded while participants performed the Stroop task.Then wavelet-based estimation of instantaneous EEG coherence was applied to investigate the synchronization of different brain regions during Stroop task.Results:A greater negativity for the in- congruent situation than congruent situation appeared from 350ms to 600ms post-stimulus onset over frontal,central,and parietal regions in Chinese Stroop task,while the negativity was absent in English Stroop task.However,not only in Chinese Stroop task but also in English Stroop task was it found signif- icantly higher EEG coherences for the incongruent situation than congruent situation over frontal,pari- etal,and frontoparietal regions before 400ms post stimulus onset atβ(13-30 Hz) frequency band.Conclu- sion:This finding indicated that wavelet-based coherence is more exquisite tool to analyze brain electro- physiological signals associated with complex cognitive task than ERP component,and that functional syn- chronization indexed by EEG coherence is enhanced at the earlier stage while processing the conflicting in- formation for the incongruent stimulus.
文摘Background The etiology and pathology of functional constipation (FC) is unclear.Some researches suggest that psychological factors may be related to this common problem.This study aimed to investigate the relationship between attention processing and emotional status in FC patients compared with healthy controls.Methods We investigated selective attention and emotional status in patients with FC using the counting Stroop task.Thirty-five FC patients (FCP group) and 24 healthy controls (HCs) underwent an event-related potential (ERP) study while performing the task.Response time,latency and amplitude of P300 were collected and compared between the two groups.The Hamilton Depression Rating Scale (HAMD-17),Hamilton Anxiety Scale (HAMA),Symptom Checklist-90 (SCL-90) and Eysenck Personality Questionnaire (EPQ) were administered prior to the counting Stroop task.Results Scores for the FCP group differed significantly from those for the HCs on the HAMD-17,HAMA,SCL-90 (Global Severity Index,Positive Symptoms Total,dimensions of somatization,obsessive-compulsive,depression,anxiety,and psychosis),as well as extraversion and neurosis dimensions of the EPQ (P〈0.05).There was no significant difference in response time or accuracy rate between the two groups (P〉0.05).ERP results showed prolonged latency at F4,additionally found enhanced activation at F3,FC1 and T8,and decreased activation at sites FC6 and P7 in the patients with FC.Statistically,significant differences of P300 latency at site F4 (P 〈0.05) and P300 amplitude at F3,F4,T8,P7,FC1 and FC6 (P〈0.05) between the patients with FC and the HC were revealed.Conclusions The findings suggest that patients with FC are more susceptible to depression and anxiety,as well as somatization,obsessive-compulsive tendencies and other neurotic personality characteristics.Patients may employ psychological defense mechanisms to avoid the pain of depression and anxiety.ERP results imply there may be some brain dysfunction and attention deficits in patients with FC.
基金the financial support of the National Key R&D Program of China(Grant No.2017YFE0112000)the Shanghai Municipal Science and Technology Major Project(Grant No.2017SHZDZX01).
文摘Light modulates human brain function through its effect on circadian rhythms,which are related to several human behavioral and physiological processes.Functional near-infrared spectroscopy(fNIRS)is a noninvasive optical neuroimaging technique used for recording brain activation during task performance.This study aimed to investigate the effects of light on cognitive function,particularly in the prefrontal cortex using fNIRS.The effect of light on cognitive modulation was analyzed using the Stroop task,which was performed on 30 participants under three different light conditions(color temperature 4500 K,2500 K,and none).The behavioral results indicated that light conditions can easily and effectively modulate the performance of tasks based on the feedback,including the response time and accuracy.fNIRS showed hemodynamic changes in the bilateral dorsolateral prefrontal cortices,and the activated brain regions varied under different light conditions.Moreover,light may be regarded as a safe,effective,inexpensive,and accessible tool for modulating human cognitive function.