Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

Background:Rosa chinensis Jacq.and Rosa rugosa Thunb.are not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional medicines.The two plants have some differences in efficacy,but the flower buds are easily confused for similar traits.In addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal roses.Therefore,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography fingerprints.Then,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large differences.Differential compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and Meigui.Results:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the samples.Through principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four groups.Partial least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavonoid glycosides,as well as phenolic acids.Eight differential components were screened out by orthogonal partial least-squares discriminant analysis and S-plot analysis.Quantitative analyses of the eight compounds,including gallic acid,ellagic acid,hyperoside,isoquercitrin,etc.,showed that Yueji was generally richer in phenolic acids and flavonoids than Meigui,and the quality of Yueji from Shandong and Hebei was better.It is worth noting that Xinjiang rose is rich in various components,which is worth focusing on more in-depth research.Conclusion:In this study,the fingerprints of Meigui and Yueji were established.The chemical components information of roses was further improved based on non-targeted metabolomics and mass spectrometry technology.At the same time,eight differential components of Meigui and Yueji were screened out and quantitatively analyzed.The research results provided a scientific basis for the quality control and rational development and utilization of Rosae Chinensis Flos and Rosae Rugosae Flos,and also laid a foundation for the study of their pharmacodynamic material basis.

Mitigation of polycyclic aromatic hydrocarbons(PAHs)in roasted beef patties by cold plasma treatment and products quality evaluation

The cold plasma(CP)technique was applied to alleviate the contamination of polycyclic aromatic hydrocarbon(PAH)in this investigation.Two different CP treatments methods were implemented in the production of beef patties,to investigate their inhibition and degradation capacity on PAHs.With 5 different cooking oils and fats addition,the inhibition mechanism of in-package cold plasma(ICP)pretreatment was explored from the aspect of raw patties fatty acids composition variation.The results of principal component analysis showed that the first two principal components accounted for more than 80%of the total variation in the original data,indicating that the content of saturated fatty acids was significantly positively correlated with the formation of PAHs.ICP pretreatment inhibited the formation of PAHs by changing the composition of fatty acids,which showed that the total amount of polyunsaturated fatty acids decreased and the total amount of monounsaturated fatty acids increased.Sensory discrimination tests demonstrated there were discernable differences between 2 CP treated samples and the controls,utilization of the ICP pretreatment in meat products processing was expected to achieve satisfying eating quality.In conclusion,CP treatment degraded PAHs through stepwise ring-opening oxidation in 2 reported pathways,the toxicity of PAHs contaminated products was alleviated after CP treatment.

A Quality Evaluation System for Dissertation Based on Fuzzy Analytic Hierarchy Process

A dissertation is a research report or scientific paper written by an author to obtain a certain degree. It reflects postgraduates’ research achievements and the educational quality of an institute, even a country. To construct an optimized quality evaluation system for postgraduate dissertation (QESPD), we summarized the influencing factors and invited 10 experienced specialists to rate and prioritize them based on fuzzy analytic hierarchy process. Four primary indicators (innovation, integrity, scientificity and normativity) and 16 sub-indicators were selected to form the evaluation system. The order of primary indicators by weight, was innovation (0.4269), scientificity (0.2807), integrity (0.1728) and normativity (0.1196). The top five sub-dimensions were theoretical originality, scientific value, data reliability, design rationality and evidence credibility. To demonstrate the effectiveness of the proposed system, a case study was performed. In the case study, it was demonstrated that the established two-index-hierarchy QESPD in this study was a more scientific and reasonable evaluation system worthy of promotion and application.

Research on the prognostic value of adjusting intraperitoneal threedimensional quality evaluation mode in laparoscopic cholecystectomy patients

BACKGROUND Benign gallbladder diseases have become a high-prevalence condition not only in China but also worldwide.The main types of benign gallbladder diseases include gallbladder polyps,acute and chronic cholecystitis,and gallstones,with gallstones being the most common,accounting for over 70%of cases.Although the mortality rate of benign gallbladder diseases is low,they carry obvious potential risks.Studies have shown that an increased incidence of benign gallbladder diseases can increase the risk of cardiovascular diseases and gallbladder cancer,resulting in a substantial disease burden on patients and their families.AIM To assess the medical utility of the Configuration-Procedure-Consequence(CPC)three-dimensional quality evaluation model in modulating the prognosis of laparoscopic cholecystectomy patients.METHODS A total of 98 patients who underwent laparoscopic cholecystectomy in our hospital from February 2020 to January 2022 were selected as the subjects.According to the random number table method,they were divided into a study group and a control group,with 49 patients in each group.The control group received routine perioperative care,while the study group had the addition of the CPC three-dimensional quality evaluation.The postoperative recovery-related indicators(time to first flatus,time to oral intake,time to ambulation,hospital stay),stress indicators(cortisol and adrenaline levels),distinctions in anxiety and RESULTS The time to first flatus,time to oral intake,time to ambulation,and hospital stay of the study group patients were obviously lower than those of the control group patients,with statistical significance(P<0.05).On the 1st day after admission,there were no obvious distinctions in cortisol and adrenaline levels in blood samples,as well as in the Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS)scores between the study group and the control group(P>0.05).However,on the 3rd day after surgery,the cortisol and adrenaline levels,as well as SAS and SDS scores of the study group patients,were obviously lower than those of the control group patients(P<0.05).The study group had 2 cases of incisional infection and 1 case of pulmonary infection,with a total incidence of complications of 6.12%(3/49),which was obviously lower than the 20.41%(10/49)in the control group(P<0.05).CONCLUSION Implementing the CPC three-dimensional quality evaluation model for patients undergoing laparoscopic cholecystectomy can help accelerate their perioperative recovery process,alleviate perioperative stress symptoms,mitigate anxiety,depression,and other adverse emotions,and to some extent,reduce the incidence of perioperative complications.

Current Status of the Application of Surgical Specialty Nursing Quality Evaluation Indicators

This paper reviews the current status of the application of surgical specialty nursing quality evaluation indicators both domestically and internationally.It covers the related concepts,theoretical foundations,construction methods,construction fields,application research,and existing shortcomings of these indicators.It suggests that scholars and researchers in the nursing field in China should base their work on mature theories,use scientific research methods,and construct a quality indicator system that aligns with China’s surgical development,is practical,unified,suitable for the local context,and beneficial for the development of the surgical nursing discipline.

Eco-environmental Quality Evaluation of Manasi River Basin in Recent 30 Years

Taking the Technical Specifications of Eco-environmental Quality Assessment enacted by the State Environmental Protection Administration in 2006 as the conceptual framework model and improving some indices and weights in the regulation,the eco-environmental assessment index system for Manas River Basin was established,and the eco-environmental quality index (EQI) of this basin from 1976 to 2005 was assessed based on the related data.The results indicated that the ecological quality index increased to 48.26 from 34.44 during 1976-2005.The biologic abundance index,vegetation coverage index and land deterioration index decreased,while there was an increase in water reticulation density index,environmental quality index and pollution load index,so the improvement and deterioration of the ecological environment coexisted in the basin.On the whole,the poor state of the basin ecological environment had turned into a general state,and the eco-environmental quality was developed towards favorable circle.The results also showed that the improved calculating method of EQI accorded with the actual situation of the research area.

Investigation on Phytoplankton and Water Quality Evaluation in Landscape Water of Campus in Nanjing Xianlin University Town

The major phytoplankton was investigated and analyzed in landscape water of six campuses in Nanjing Xianlin University Town,and water quality was evaluated by single factor assessment method and comprehensive weighted evaluation method.The result showed that the major phytoplankton groups were Cyanophyta,Chlorophyta and Bacillariophyta.Besides,each evaluation indicator showed that waterbodies in four campuses were eutrophicated and result of single factor evaluation showed water quality all belonged to poor category V.The result of comprehensive weighted assessment showed that waters in Nanjing Normal University and Nanjing University of Posts and Telecommunications were seriously polluted,cyanobacterial bloom appearing.Waters in Nanjing University of Chinese Medicine and Nanjing Forest Police College hadn't been eutrophicated.

Quality Synthetic Evaluation of Urea Formaldehyde Foam Substrate in Turf Establishment

[Objective]The aim of this study was to explore the feasibility of three kinds of urea formaldehyde foam substrate in tall fescue establishment as well as to study on evaluation of turf quality.[Method]The visual estimates,ecological quality estimates and utility quality estimates were used as the 1st level indicators,and the density,color,texture,uniformity,green period,cover degree,biomass,emergence energy,growth rate and turf-forming time were used as the corresponding 2nd level indicators.With T.L.Satty＇s method Analytic Hierarchy Process（AHP） and the fuzzy synthesis evaluation method,the weight ratio of matrix was obtained and the synthetic evaluation result was accorded with facts,then it could be regarded as the satisfying value of weight.[Result]The quality of three covering soil treatments was better than that of uncovering treatment and conventional treatment,the quality synthetic evaluation of F1 was the best,which was about 0.770.[Conclusion]Urea formaldehyde foam substrate showed high quality for turf establishment,which could be further spread and applied.

Application of Fuzzy Comprehensive Evaluation Method Based on Entropy Weight to Evaluate Pond Water Quality

[Objective] This study was to provide references for the evaluation of water quality in aquaculture ponds by evaluating the pond water quality using fuzzy comprehensive evaluation method based on entropy weight. [Method] The fuzzy compre- hensive evaluation method based on entropy weight was used to evaluate the water quality in the ponds with Ukraine scale carp （Cyprinus carpio） as the main cultivated fish. The average size of the fish was 71.4 g/ind, and totally three groups of pond were set with the population density of 6 000, 9 000, 12 000 ind/hm2. [Result] According to the GB3838-2002 Environmental Quality Standards for Surface Water of China, the water quality of 6 000 ind/hm2 group was Grade I, and the water quality of 9 000 and 12 000 ind/hm2 were Grade V. [Conclusion] With the increasing of feeding density, the pond water quality would worsen, however, there is no difference on water quality between 9 000 and 12 000 ind/hm2 groups.

Comprehensive evaluation of water quality parameters in Tianjin Dagu Dainage Canal

In this paper, some indices of sulfide, organic carbon, oil and heavy metals （copper, lead, zinc, cadmium, mercury, arsenic and chromium） in the sediments from Dagu Dainage Canal at the Bohai Bay during four seasons in 2012 - 2013 are selected, and Water Quality Pollution Index （API） is applied to evaluate water quality indices, aiming for the systematic evaluation of the water quality of Dagu Dainage Canal. The results showed that four stations of D3, D6, D7and D9 for S2 had the type Ⅱand Ⅲ of water; others had the type Ⅰ ; the total level of TOC, TPH, Cu, Pb, Zn, Cd, Hg, As and Cr were type Ⅰ, Ⅳ, Ⅱ, Ⅴ, Ⅱ, Ⅴ, Ⅲ, Vand Ⅴ. Water Quality Pollution Index （API） was 3.28, which illustrated Dagu Dainage Canal was in the state of contamination and the degree of pollution exceeded the standard functional areas.

Soil Environmental Quality Evaluation for Wasteland of Coalmine Tailing Polluted by Heavy Metals in Mingshan of Guangdong

ln order to appraise scientifical y the heavy metal contamination in waste-land of coalmine tailing in Mingshan of Guangdong, the 5 soil samples in wasteland of coalmine tailing were col ected in November 2010 to March 2011. The 7 heavy metals content in the contaminated soil was measured by atomic absorption spec-trophotometry. The results showed the pH of the wasteland soil ranged from 2.87 to 6.16, and the soil was relatively infertile. The soil was mainly pol uted by Cd and Mn. The Cd content in wasteland soil ranged from 0.759 mg/kg to 3.109 mg/kg with an average content of 2.052 mg/kg, which was much higher than the standard content. The Mn content ranged from 387.057 to 488.660 mg/kg with an average content of 421.215 mg/kg, which was much higher than the standard content. The Nemerow integrated pol ution indexes showed the sample 1, sample 4 and sample 5 were of heavy pol ution, and sample 2 and sample 3 were of moderate pol ution.

Study on the Environmental Quality Evaluation of Waterscape Resources Area

The environmental quality of a region is co-determined by diversified factors among which there are always dominant ones or restrictive ones that play a significant role in the evolution of environmental quality.The quality of waterscape environment surely is correlated with water,the core element in waterscape.Taking Huangguoshu Scenic Area for an example,restrictive factors of the waterscape environmental quality were analyzed in this study,and basic approaches to evaluate the environmental quality of waterscapes were put forward.

Fuzzy Comprehensive Evaluation of Urban Traffic Environment Quality

In this paper, traffic environment quality assessment is achieved by applying fuzzy mathematics methods. Set up an assessment system, determine assessment criterion, formulate membership function, make program designs and conduct example analysis. The evaluation result is consistent with the real case. So that the method of the fuzzy evaluation is a good one for the environment quality assessment.

Development of Bean Dreg Bread and Quality Evaluation

The research compared differences between bean dreg breads and common breads from perspectives of sensory quality, texture and taste.

Analysis and Evaluation of Heavy Metal Environmental Quality of Irrigation Water in Vegetable Farmlands of Shandong Province

[Objective] The aim was to evaluate heavy metal environmental quality of irrigation water in vegetable farmlands of Shandong Province. [Method] Heavy metal contents including Hg,Cd,As,Cr (+6),Pb,Cu and Zn in irrigation water of main vegetable farmlands of Shandong Province were investigated by randomly sampling,and the environmental quality conditions of these heavy metals were evaluated by methods of single quality index and complex quality index. [Result] The results showed that the average contents of heavy metals in irrigation water of Shouguang,Laiyang,Jinxiang and Zhangqiu were all far lower than the limit values prescribed by 'Farmland Environmental Quality Evaluation Standards for Edible Agricultural Products' (HJ332-2006),and no heavy metal was found beyond the limit value in every sample. The single quality indices of the 7 elements in the studied 4 places were all lower than 0.5. The comprehensive quality index of the seven elements was 0.317 8 in Shouguang,0.320 4 in Laiyang,0.232 6 in Jinxiang,and 0.260 7 in Zhangqiu. The environmental quality of irrigation water in the studied four places were all set at the first class. [Conclusion] The environmental quality of irrigation water in the 4 places belonged to clean level and were fit for the plantation of no pollution vegetables.

Entropy method for determination of weight of evaluating indicators in fuzzy synthetic evaluation for water quality assessment

Considering the difficulty of fuzzy synthetic evaluation method in calculation of the multiple factors and ignorance of the relationship among evaluating objects, a new weight evaluation process using entropy method was introduced. This improved method for determination of weight of the evaluating indicators was applied in water quality assessment of the Three Gorges reservoir area. The results showed that this method was favorable for fuzzy synthetic evaluation when there were more than one evaluating objects. One calculation was enough for calculating every monitoring point. Compared with the original evaluation method, the method predigested the fuzzy synthetic evaluation process greatly and the evaluation results are more reasonable.

Application of Projection Pursuit Evaluation Model Based on Real-Coded Accelerating Genetic Algorithm in Evaluating Wetland Soil Quality Variations in the Sanjiang Plain, China

A new technique of dimension reduction named projection pursuit is applied to model and evaluatewetland soil quality variations in the Sanjiang Plain, Helongjiang Province, China. By adopting the im-proved real-coded accelerating genetic algorithm (RAGA), the projection direction is optimized and multi-dimensional indexes are converted into low-dimensional space. Classification of wetland soils and evaluationof wetland soil quality variations are realized by pursuing optimum projection direction and projection func-tion value. Therefore, by adopting this new method, any possible human interference can be avoided andsound results can be achieved in researching quality changes and classification of wetland soils.

Comprehensive Evaluation on the Irrigation Water Quality in Turpan City Based on Matter Element Analysis Method

Matter-element analysis method was used to construct the comprehensive matter-element model for the evaluation of the quality of various kinds of irrigation water in Turpan City to evaluate the quality of irrigation water（such as river water,spring water, Karez well water, pumped well water） in Turpan City, Xinjiang. The results showed that the quality of the irrigation water was the best in October,which was in Grade I or Grade 2; in May, the quality of some of the irrigation water became poorer to Grade II, which was easy to soil salinization; in March, the detected qualities of the water samples water from the Meiyaogou basin were all in Grade IV, which was not suitable for farmland irrigation. The comparison on the evaluation results of matter-element analysis and fuzzy evaluation method showed that the results of the 2 methods were almost consistent with each other, and showed good uniformity.

Evaluation, prediction, and protection of water quality in Danjiangkou Reservoir, China

The water quality in the Danjiangkou Reservoir has attracted considerable attention from the Chinese public and government since the announcement of the Middle Route of the South to North Water Diversion Project （SNWDP）, which commenced transferring water in 2014. Integrated research on the evaluation, prediction, and protection of water quality in the Danjiangkou Reservoir was carried out in this study in order to improve environmental management. Based on 120 water samples, wherein 17 water quality indices were measured at 20 monitoring sites, a single factor evaluation method was used to evaluate the current status of water quality. The results show that the main indices influencing the water quality in the Danjiangkou Reservoir are total phosphorus （TP）, permanganate index （CODM,）, dissolved oxygen （DO）, and five-day biochemical oxygen demand （BODs）, and the concentrations of TP, BODs, ammonia nitrogen （NH3--N）, CODM,, DO, and anionic surfactant （Surfa） do not reach the specified standard levels in the tributaries. Seasonal Mann--Kendall tests indicated that the CODMn concentration shows a highly significant increasing trend, and the TP concentration shows a significant increasing trend in the Danjiangkou Reservoir. The distribution of the main water quality indices in the Danjiangkou Reservoir was predicted using a two-dimensional water quality numerical model, and showed that the sphere of influence from the tributaries can spread across half of the Han Reservoir if the pollutants are not controlled. Cluster analysis （CA） results suggest that the Shending River is heavily polluted, that the Jianghe, Sihe, and Jianhe rivers are moderately polluted, and that they should be the focus of environmental remediation.