The petroleum compounds were photocatalytically remediated from water using graphene (G)- titanium oxide (TiO<sub>2</sub>) nanocomposite material in visible light radiation. The G-TiO<sub>2</sub&g...The petroleum compounds were photocatalytically remediated from water using graphene (G)- titanium oxide (TiO<sub>2</sub>) nanocomposite material in visible light radiation. The G-TiO<sub>2</sub> nanocomposite was synthesized using sol-gel technique, and its structural & morphological properties were studied using scanning electron microscopy (SEM), X-ray diffraction (XRD), transmission electron microscopy (TEM), particle analyzer and UV-Visible spectroscopy (UV-Vis) measurement techniques. Various petroleum-based chemicals (toluene, naphthalene and diesel) were remediated, and samples were analyzed using optical and gas chromatography (GC) techniques. The mechanism of photocatalytic remediation of petroleum compounds using G-TiO<sub>2</sub> nanomaterials is understood and well compared with data available in literature.展开更多
A BaF2 time differential perturbed angular distribution spectrometer has been established at the HI-13 tandem accelerator in CIAE. The time resolution of the spectrometer is 195 ps and the nonlinearity is less than 2 ...A BaF2 time differential perturbed angular distribution spectrometer has been established at the HI-13 tandem accelerator in CIAE. The time resolution of the spectrometer is 195 ps and the nonlinearity is less than 2 %. The spectrometer works very stably and no time drift is found over a period of experimelltal ruffs. This spectrometer has been successfully used in the g-factor measurement of 43 Sc (19/2-,3.1232 MeV).展开更多
目的:研究微小RNA(microRNA,miR)-218-5p靶向调控三磷酸腺苷结合盒超家族G家族第2个成员(ATP-binding cassette sub-family G member 2,ABCG2)基因对Tca-8113细胞的增殖、迁移和侵袭的影响,并探讨其机制。方法:运用实时荧光定量聚合酶...目的:研究微小RNA(microRNA,miR)-218-5p靶向调控三磷酸腺苷结合盒超家族G家族第2个成员(ATP-binding cassette sub-family G member 2,ABCG2)基因对Tca-8113细胞的增殖、迁移和侵袭的影响,并探讨其机制。方法:运用实时荧光定量聚合酶链反应(quantitative Real-time PCR,qRT-PCR)与Western blot检测Tca-8113细胞和NOK细胞中miR-218-5p和ABCG2的表达。通过双荧光素酶报告基因实验检测miR-218-5p和ABCG2靶向关系。用脂质体法将miR-218-5p mimic、ABCG2小干扰RNA(interfering RNA,siRNA)、miR-218-5p mimic+pcDNA-ABCG2分别转染至Tca-8113细胞中,噻唑蓝(methyl thiazol tetrazolium,MTT)法、Transwell法检测Tca-8113细胞的增殖、迁移和侵袭。结果:与NOK细胞比较,Tca-8113细胞miR-218-5p呈显著低表达,ABCG2呈显著高表达(P<0.05)。过表达miR-218-5p、抑制ABCG2均可抑制Tca-8113细胞的增殖和迁移(P<0.05)。双荧光素酶报告基因实验证实miR-218-5p与ABCG2的靶向结合关系。过表达ABCG2可逆转上调miR-218-5p对Tca-8113细胞增殖、迁移和侵袭的抑制作用。结论:上调miR-218-5p的表达可靶向调控ABCG2,抑制Tca-8113细胞的增殖、迁移和侵袭,将可为口腔鳞状细胞癌的治疗提供新的靶点。展开更多
文章分析了M A S建模方法学提出的动因,指出了M A S建模中的关键问题;阐述了基于A gen t的建模方法学分析阶段的过程及其不足,研究了对系统子目标进行表述、求解的规范化工具——G/A矩阵及其求解方法;并在此基础上提出了一种新的M A S...文章分析了M A S建模方法学提出的动因,指出了M A S建模中的关键问题;阐述了基于A gen t的建模方法学分析阶段的过程及其不足,研究了对系统子目标进行表述、求解的规范化工具——G/A矩阵及其求解方法;并在此基础上提出了一种新的M A S中个体A gen t的识别方法,最后通过实例说明该方法简单易行。展开更多
As recounted in this paper, the idea of groups is one that has evolved from some very intuitive concepts. We can do binary operations like adding or multiplying two elements and also binary operations like taking the ...As recounted in this paper, the idea of groups is one that has evolved from some very intuitive concepts. We can do binary operations like adding or multiplying two elements and also binary operations like taking the square root of an element (in this case the result is not always in the set). In this paper, we aim to find the operations and actions of Lie groups on manifolds. These actions can be applied to the matrix group and Bi-invariant forms of Lie groups and to generalize the eigenvalues and eigenfunctions of differential operators on R<sup>n</sup>. A Lie group is a group as well as differentiable manifold, with the property that the group operations are compatible with the smooth structure on which group manipulations, product and inverse, are distinct. It plays an extremely important role in the theory of fiber bundles and also finds vast applications in physics. It represents the best-developed theory of continuous symmetry of mathematical objects and structures, which makes them indispensable tools for many parts of contemporary mathematics, as well as for modern theoretical physics. Here we did work flat out to represent the mathematical aspects of Lie groups on manifolds.展开更多
Idiopathic membranous nephropathy (IMN) is a Th2 nephritogenic immune disorder. It is caused by the accumulation of immune complexes, mainly IgG4, at the basal glomerular membrane that leads to the damage of the glome...Idiopathic membranous nephropathy (IMN) is a Th2 nephritogenic immune disorder. It is caused by the accumulation of immune complexes, mainly IgG4, at the basal glomerular membrane that leads to the damage of the glomerular barrier and subsequent injury of podocytes. Our aim was to evaluate the relationship between cytokine polymorphisms and IMN. We investigated the cytokine polymorphisms in forty-five patients and one hundred twenty-four healthy individuals, using polymerase chain reaction-sequence specific primers (PCR-SSP). We showed a significant increase in allelic frequencies of the alleles -590T and -33T of IL-4 gene and -308A of TNF-α gene, in IMN patients. In addition, we observed an increased frequency of allele -1082G in IL-10 gene in a subgroup of patients with CD4/CD8 ratio major than 2, when compared either to control subjects or the subgroup of patients with CD4/CD8 ratio minor than 2. Moreover, analyzing the Th1/Th2 cytokines in serum and urine, we found increased levels of IL-4 in serum and IL-5 in urine of patients. We deduce that the alleles -590T and -33T of IL-4 and -308A of TNF-α may be associated with IMN. In addition, in patients with increased T helper lymphocytes, IL-10 -1082G polymorphism can also play a role in the pathogenesis of the disease. These findings remark the role of Th2 immune response and suggest the association between polymorphic variants of IL-4, IL-10 and TNF-α genes with the development of IMN and therefore giving a better insight in pathogenesis of this disease.展开更多
文摘The petroleum compounds were photocatalytically remediated from water using graphene (G)- titanium oxide (TiO<sub>2</sub>) nanocomposite material in visible light radiation. The G-TiO<sub>2</sub> nanocomposite was synthesized using sol-gel technique, and its structural & morphological properties were studied using scanning electron microscopy (SEM), X-ray diffraction (XRD), transmission electron microscopy (TEM), particle analyzer and UV-Visible spectroscopy (UV-Vis) measurement techniques. Various petroleum-based chemicals (toluene, naphthalene and diesel) were remediated, and samples were analyzed using optical and gas chromatography (GC) techniques. The mechanism of photocatalytic remediation of petroleum compounds using G-TiO<sub>2</sub> nanomaterials is understood and well compared with data available in literature.
文摘A BaF2 time differential perturbed angular distribution spectrometer has been established at the HI-13 tandem accelerator in CIAE. The time resolution of the spectrometer is 195 ps and the nonlinearity is less than 2 %. The spectrometer works very stably and no time drift is found over a period of experimelltal ruffs. This spectrometer has been successfully used in the g-factor measurement of 43 Sc (19/2-,3.1232 MeV).
文摘文章分析了M A S建模方法学提出的动因,指出了M A S建模中的关键问题;阐述了基于A gen t的建模方法学分析阶段的过程及其不足,研究了对系统子目标进行表述、求解的规范化工具——G/A矩阵及其求解方法;并在此基础上提出了一种新的M A S中个体A gen t的识别方法,最后通过实例说明该方法简单易行。
文摘As recounted in this paper, the idea of groups is one that has evolved from some very intuitive concepts. We can do binary operations like adding or multiplying two elements and also binary operations like taking the square root of an element (in this case the result is not always in the set). In this paper, we aim to find the operations and actions of Lie groups on manifolds. These actions can be applied to the matrix group and Bi-invariant forms of Lie groups and to generalize the eigenvalues and eigenfunctions of differential operators on R<sup>n</sup>. A Lie group is a group as well as differentiable manifold, with the property that the group operations are compatible with the smooth structure on which group manipulations, product and inverse, are distinct. It plays an extremely important role in the theory of fiber bundles and also finds vast applications in physics. It represents the best-developed theory of continuous symmetry of mathematical objects and structures, which makes them indispensable tools for many parts of contemporary mathematics, as well as for modern theoretical physics. Here we did work flat out to represent the mathematical aspects of Lie groups on manifolds.
文摘Idiopathic membranous nephropathy (IMN) is a Th2 nephritogenic immune disorder. It is caused by the accumulation of immune complexes, mainly IgG4, at the basal glomerular membrane that leads to the damage of the glomerular barrier and subsequent injury of podocytes. Our aim was to evaluate the relationship between cytokine polymorphisms and IMN. We investigated the cytokine polymorphisms in forty-five patients and one hundred twenty-four healthy individuals, using polymerase chain reaction-sequence specific primers (PCR-SSP). We showed a significant increase in allelic frequencies of the alleles -590T and -33T of IL-4 gene and -308A of TNF-α gene, in IMN patients. In addition, we observed an increased frequency of allele -1082G in IL-10 gene in a subgroup of patients with CD4/CD8 ratio major than 2, when compared either to control subjects or the subgroup of patients with CD4/CD8 ratio minor than 2. Moreover, analyzing the Th1/Th2 cytokines in serum and urine, we found increased levels of IL-4 in serum and IL-5 in urine of patients. We deduce that the alleles -590T and -33T of IL-4 and -308A of TNF-α may be associated with IMN. In addition, in patients with increased T helper lymphocytes, IL-10 -1082G polymorphism can also play a role in the pathogenesis of the disease. These findings remark the role of Th2 immune response and suggest the association between polymorphic variants of IL-4, IL-10 and TNF-α genes with the development of IMN and therefore giving a better insight in pathogenesis of this disease.