Gastric lipomas are rare tumors, accounting for 2%-3% of all benign gastric tumors. They are of submucosal or extremely rare subserosal origin. Although most gastric lipomas are usually detected incidentally, they can...Gastric lipomas are rare tumors, accounting for 2%-3% of all benign gastric tumors. They are of submucosal or extremely rare subserosal origin. Although most gastric lipomas are usually detected incidentally, they can cause abdominal pain, dyspeptic disorders, obstruction, invagination, and hemorrhages. Subserosal gastric lipomas are rarely symptomatic. There is no report on treatment of subserosal gastric lipomas in the English literature. We present a case of a 50-year-old male with symptomatic subserosal gastric lipoma which was successfully managed with removal, enucleation of lipoma, explorative gastrotomy and edge resection for histology check of gastric wall. The incidence of gastric lipoma, advanced diagnostic possibilities and their role in treatment modalities are discussed.展开更多
AIM:To investigate the protective effect of subserosal injection of hyaluronic acid(HA) after endoscopic resection(ER) using ex vivo and in vivo studies.METHODS:As the first examination,technical application of subser...AIM:To investigate the protective effect of subserosal injection of hyaluronic acid(HA) after endoscopic resection(ER) using ex vivo and in vivo studies.METHODS:As the first examination,technical application of subserosal injection was tested 10 times using resected porcine stomachs.As the second examination,ER was applied to make six mucosal defects per stomach in three live minipigs and thermal damage was given on the proper muscle layer by using hemostatic forceps.Following the thermocoagulation,1 mL of normal saline and HA,respectively,was injected targeting the subserosal layer in two mucosal defects each and the rest kept no injection as the control.The minipigs were recovered from the anesthesia and kept fasting until euthanasia which was carried out around 24 h after the procedures.RESULTS:Ex vivo study revealed that complete and partial subserosal injection was possible two(20%) and four(40%) times,respectively.In vivo study revealed that no postoperative perforation occurred at any point of the thermocoagulation.Apparent retention of hyaluronic acid was identified at only two(33%) points where HA was injected.CONCLUSION:This study failed to show preventative effects of subserosal injection of HA on postoperative perforation due to technical faults.However,this concept has a possibility to change strategy of ER with further technical innovation.展开更多
文摘Gastric lipomas are rare tumors, accounting for 2%-3% of all benign gastric tumors. They are of submucosal or extremely rare subserosal origin. Although most gastric lipomas are usually detected incidentally, they can cause abdominal pain, dyspeptic disorders, obstruction, invagination, and hemorrhages. Subserosal gastric lipomas are rarely symptomatic. There is no report on treatment of subserosal gastric lipomas in the English literature. We present a case of a 50-year-old male with symptomatic subserosal gastric lipoma which was successfully managed with removal, enucleation of lipoma, explorative gastrotomy and edge resection for histology check of gastric wall. The incidence of gastric lipoma, advanced diagnostic possibilities and their role in treatment modalities are discussed.
文摘AIM:To investigate the protective effect of subserosal injection of hyaluronic acid(HA) after endoscopic resection(ER) using ex vivo and in vivo studies.METHODS:As the first examination,technical application of subserosal injection was tested 10 times using resected porcine stomachs.As the second examination,ER was applied to make six mucosal defects per stomach in three live minipigs and thermal damage was given on the proper muscle layer by using hemostatic forceps.Following the thermocoagulation,1 mL of normal saline and HA,respectively,was injected targeting the subserosal layer in two mucosal defects each and the rest kept no injection as the control.The minipigs were recovered from the anesthesia and kept fasting until euthanasia which was carried out around 24 h after the procedures.RESULTS:Ex vivo study revealed that complete and partial subserosal injection was possible two(20%) and four(40%) times,respectively.In vivo study revealed that no postoperative perforation occurred at any point of the thermocoagulation.Apparent retention of hyaluronic acid was identified at only two(33%) points where HA was injected.CONCLUSION:This study failed to show preventative effects of subserosal injection of HA on postoperative perforation due to technical faults.However,this concept has a possibility to change strategy of ER with further technical innovation.
