The direct arylation of substituted pyridines with several arylboronic acids has been developed.This transformation could proceed readily at ambient temperature using inexpensive reagents:iron(Ⅱ)oxalate as a catalyst...The direct arylation of substituted pyridines with several arylboronic acids has been developed.This transformation could proceed readily at ambient temperature using inexpensive reagents:iron(Ⅱ)oxalate as a catalyst,potassium persulfate as a co-oxidant,which can afford the arylated products in mild to good yields.The mechanism is presumed to proceed through a nucleophilic radical addition to the pyridines with in situ reoxidation.展开更多
Seven pyrimethanil salts were synthesized by organic base containing nitrogen atom reacting with substituted pyridine acids. They are reported for the first time. Their structures have been confirmed by IR, ^1H NMR an...Seven pyrimethanil salts were synthesized by organic base containing nitrogen atom reacting with substituted pyridine acids. They are reported for the first time. Their structures have been confirmed by IR, ^1H NMR and elemental analysis. The preliminary toxicity tests indicated that most of them exhibited excellent fungicidal activities. The relationship between the structures and the fungicidal activities of the compounds was discussed.展开更多
基金We are thankful for the financial support of“National Natural Science Foundation of China(21302014)”“Program of Applied Basic Research in Changzhou(CJ20130003)”“Open Project of Jiangsu Province Key Laboratory of Fine Petrochemical Engineering(KF1304)”.
文摘The direct arylation of substituted pyridines with several arylboronic acids has been developed.This transformation could proceed readily at ambient temperature using inexpensive reagents:iron(Ⅱ)oxalate as a catalyst,potassium persulfate as a co-oxidant,which can afford the arylated products in mild to good yields.The mechanism is presumed to proceed through a nucleophilic radical addition to the pyridines with in situ reoxidation.
基金Project supported by the Natural Science Foundation of Shanxi Province （No. 2001H11） and the Project of Northwest University.
文摘Seven pyrimethanil salts were synthesized by organic base containing nitrogen atom reacting with substituted pyridine acids. They are reported for the first time. Their structures have been confirmed by IR, ^1H NMR and elemental analysis. The preliminary toxicity tests indicated that most of them exhibited excellent fungicidal activities. The relationship between the structures and the fungicidal activities of the compounds was discussed.
