Conformation analysis of the model compounds for tunicamycin V and its natural donor substrate, UDP-N-acetylglucose, is performed to reveal the detail of the inhibition process.
Here,a novel Au Wedge-enhanced Raman spectroscopy(WERS)substrate is proposed.The electric field enhancement factor and the effective mode field radius with varying geometry parameters are investigated.The proper excit...Here,a novel Au Wedge-enhanced Raman spectroscopy(WERS)substrate is proposed.The electric field enhancement factor and the effective mode field radius with varying geometry parameters are investigated.The proper excitation wavelength 633 nm is obtained.The practical application of WERS substrate is discussed.The Au WERS not only can provide a continuous extremely highly localized electric field as surface-enhanced Raman scattering(SERS)hotspots,but also can offer 10 orders of magnitude of SERS enhancement factor.The corresponding results reveal that WERS substrate will be widely applied in optics,biology,chemistry and other fields.展开更多
文摘Conformation analysis of the model compounds for tunicamycin V and its natural donor substrate, UDP-N-acetylglucose, is performed to reveal the detail of the inhibition process.
基金supported by the National Natural Science Foundation of China(No.61905100)the Fundamental Research Funds for the Central Universities(No.lzujbky-2020-65)。
文摘Here,a novel Au Wedge-enhanced Raman spectroscopy(WERS)substrate is proposed.The electric field enhancement factor and the effective mode field radius with varying geometry parameters are investigated.The proper excitation wavelength 633 nm is obtained.The practical application of WERS substrate is discussed.The Au WERS not only can provide a continuous extremely highly localized electric field as surface-enhanced Raman scattering(SERS)hotspots,but also can offer 10 orders of magnitude of SERS enhancement factor.The corresponding results reveal that WERS substrate will be widely applied in optics,biology,chemistry and other fields.
