OBJECTIVE To provide the evidence of predicting and preventing the postoperative recurrence by investigating the relationship between the recurring types of colorectal carcinoma （CRC） after radical resection and cli...OBJECTIVE To provide the evidence of predicting and preventing the postoperative recurrence by investigating the relationship between the recurring types of colorectal carcinoma （CRC） after radical resection and clinicopathologic factors.METHODS Data from 464 CRC patients in stage Ⅰ-Ⅲ who were admitted to our hospital during a period from January 1998 to December 2002 and underwent radical surgery, were collected, and retrospective analysis of the clinicopathologic data from 90 out of the 464 CRC patients, who developed postoperative recurrence was conducted. The 90 patients were divided into 2 groups based on the recurrence time （RT）. Those with a RT of ≤ 30 months were classified into the early recurrence （ER） group and those with RT of 〉 30 months were classified into late recurrence （LR） group. The X2 test was used for univariate analysis, and binomial logistic regression analysis for multivariate analysis.RESULTS There were 78 patients （86%） in the ER group and 12 （14%） in the LR group. The median recurrence time （MRT） was 35.1 months, 13.6 months, and 12.9 months in CRC patients with stage-Ⅰ, stage-Ⅱ and stage-Ⅲ, respectively. There were significant differences in RT among the groups （P = 0.001）. In the 90 patients, the MRT was 17.4 months. The median time （MT） was 16.9 months in patients with regional recurrence, 13.3 months in patients with single recurrence, and 7.7 months in patients with multiple metastases. Univariate analysis indicated that the depth of tumor infiltration, the number of positive lymph nodes, and the macroscopic types of the primary tumor were the factors affecting the relapse of the tumor. The multivariate analysis revealed that the depth of tumor infiltration was the independent factor affectin~ the time of ER （P = 0.049）.CONCLUSION Most of CRC patients receiving radical surgery for colorectal cancer occur recurrence within 30 months after the first operation, nevertheless, LR occurs in some CRC patients over 30 months after the surgery. The time interval varies in different types of recurrence. Distant metastasis is seen mainly in the cases with postoperative ER, and regional recurrence in the cases with LR. The depth of tumor infiltration is an independent predictor affecting the postoperative RT of CRC, and the tumor infiltration into, or beyond the seromembranous layer is considered as independent factor affecting the ER of CRC.展开更多
Objective：To report the results of repair of skin defects in the extremities with arterialized venous flap harvested from the lateral aspect of the dorsum of the foot.Methods：Six cases of skin and soft tissue defect...Objective：To report the results of repair of skin defects in the extremities with arterialized venous flap harvested from the lateral aspect of the dorsum of the foot.Methods：Six cases of skin and soft tissue defects over the foot and hands were resurfaced by free arterialized venous flaps,including five patients with skin defects of the hands,and one with defects at the dorsum of the foot.The flaps were harvested from the lateral aspect of the dorsum of the foot with the sizes ranging from 2 cm×5.5 cm to 6 cm×11 cm.Two veins at the proximal margin of the flap were retained,one of which was anastomosed to a recipient bed artery to provide arterial inflow and the other was anastomosed to a recipient bed vein for venous outflow.Results：All flaps demonstrated mild edema and survived completely.Blisters appeared on four flaps.Using this technique,we achieved good functional and cosmetic results in this series.Conclusions：Dorsalis pedis arterialized venous flap with rich vascular communications could enhance peripheral perfusion and decrease congestion of venous flaps,thereby improves reliability and utility for extremity reconstruction.展开更多
文摘OBJECTIVE To provide the evidence of predicting and preventing the postoperative recurrence by investigating the relationship between the recurring types of colorectal carcinoma （CRC） after radical resection and clinicopathologic factors.METHODS Data from 464 CRC patients in stage Ⅰ-Ⅲ who were admitted to our hospital during a period from January 1998 to December 2002 and underwent radical surgery, were collected, and retrospective analysis of the clinicopathologic data from 90 out of the 464 CRC patients, who developed postoperative recurrence was conducted. The 90 patients were divided into 2 groups based on the recurrence time （RT）. Those with a RT of ≤ 30 months were classified into the early recurrence （ER） group and those with RT of 〉 30 months were classified into late recurrence （LR） group. The X2 test was used for univariate analysis, and binomial logistic regression analysis for multivariate analysis.RESULTS There were 78 patients （86%） in the ER group and 12 （14%） in the LR group. The median recurrence time （MRT） was 35.1 months, 13.6 months, and 12.9 months in CRC patients with stage-Ⅰ, stage-Ⅱ and stage-Ⅲ, respectively. There were significant differences in RT among the groups （P = 0.001）. In the 90 patients, the MRT was 17.4 months. The median time （MT） was 16.9 months in patients with regional recurrence, 13.3 months in patients with single recurrence, and 7.7 months in patients with multiple metastases. Univariate analysis indicated that the depth of tumor infiltration, the number of positive lymph nodes, and the macroscopic types of the primary tumor were the factors affecting the relapse of the tumor. The multivariate analysis revealed that the depth of tumor infiltration was the independent factor affectin~ the time of ER （P = 0.049）.CONCLUSION Most of CRC patients receiving radical surgery for colorectal cancer occur recurrence within 30 months after the first operation, nevertheless, LR occurs in some CRC patients over 30 months after the surgery. The time interval varies in different types of recurrence. Distant metastasis is seen mainly in the cases with postoperative ER, and regional recurrence in the cases with LR. The depth of tumor infiltration is an independent predictor affecting the postoperative RT of CRC, and the tumor infiltration into, or beyond the seromembranous layer is considered as independent factor affecting the ER of CRC.
文摘Objective：To report the results of repair of skin defects in the extremities with arterialized venous flap harvested from the lateral aspect of the dorsum of the foot.Methods：Six cases of skin and soft tissue defects over the foot and hands were resurfaced by free arterialized venous flaps,including five patients with skin defects of the hands,and one with defects at the dorsum of the foot.The flaps were harvested from the lateral aspect of the dorsum of the foot with the sizes ranging from 2 cm×5.5 cm to 6 cm×11 cm.Two veins at the proximal margin of the flap were retained,one of which was anastomosed to a recipient bed artery to provide arterial inflow and the other was anastomosed to a recipient bed vein for venous outflow.Results：All flaps demonstrated mild edema and survived completely.Blisters appeared on four flaps.Using this technique,we achieved good functional and cosmetic results in this series.Conclusions：Dorsalis pedis arterialized venous flap with rich vascular communications could enhance peripheral perfusion and decrease congestion of venous flaps,thereby improves reliability and utility for extremity reconstruction.
