AIM: To describe survival trends in patients in Northeast China diagnosed as gastric cancer. METHODS: A review of all inpatient and outpatient records of gastric cancer patients was conducted in the First Affiliated H...AIM: To describe survival trends in patients in Northeast China diagnosed as gastric cancer. METHODS: A review of all inpatient and outpatient records of gastric cancer patients was conducted in the First Affiliated Hospital of China Medical University. All the gastric cancer patients who satisfied the inclusion criteria from January 1, 1980 through December 31, 2003 were included in the study. The main outcomes were based on median survival and 3-year and 5-year survival rates, by decade of diagnosis. RESULTS: From 1980 through 2003, the median survival for patients with gastric cancer (n = 1604) increased from 33 mo to 49 mo. The decade of diagnosis was not significantly associated with patient survival for gastric cancer (P = 0.084 for overall survival, and P = 0.150 for 5-year survival); however, the survival rate of the 2000s was remarkably higher than that of the 1980s (P = 0.019 for overall survival, and P = 0.027 for 5-year survival).CONCLUSION: There was no significant difference of survival among each period; however, the survival rate of the 2000s was remarkably higher than that of the 1980s.展开更多
Background:There have been few reports on long-term survival of gastric cancer patients.This study analyzed the survival data of gastric cancer patients obtained from the population-based Qidong Cancer Registry betwee...Background:There have been few reports on long-term survival of gastric cancer patients.This study analyzed the survival data of gastric cancer patients obtained from the population-based Qidong Cancer Registry between 1972 and 2011,providing a basis for evaluation of gastric cancer treatment and prognosis.Methods:The cumulative observed survival rate and relative survival rate of gastric cancer patients were calculated using Hakulinen's method via the SURV3.01 software,which was developed by the Finnish Cancer Registry.The date of the last follow-up for the survival status of the 15,401 registered cases was April 30,2012.Results:The 1-,5-,10-,20-,and 30-year observed survival rates were 33.82%,14.18%,10.35%,6.63%,and 4.19%,respectively,and the 1-,5-,10-,20-,and 30-year relative survival rates were 35.43%,18.13%,17.50%,21.96%,and32.84%,respectively.For males,the corresponding observed survival rates were 34.50%,14.40%,10.42%,6.46%,and4.05%,and the corresponding relative survival rates were 36.23%,18.67%,18.28%,23.73%,and 38.61%.For females,the corresponding observed survival rates were 32.62%,13.80%,10.22%,6.95%,and 4.46%,and the corresponding relative survival rates were 34.03%,17.21%,16.28%,19.70%,and 26.78%.Significant differences in relative survival rates were observed between sexes(P=0.003).For the 15-34,35-44,45-54,55-64,65-74,and 75+ age groups,the 5-year relative survival rates were 16.13%,21.77%,18.63%,12.61%,7.99%,and 2.94%,respectively,and the 10-year relative survival rates were 16.49%,22.83%,20.50%,15.97%,15.88%,and 15.73%,respectively.Remarkable improvement could be observed for the 5-,10-,and 15-year relative survival rates in Qidong beginning in the 1980 s.Conclusion:The survival outcome of registered gastric cancer cases in Qidong showed gradual progress over the past two decades.展开更多
Survival of patients with childhood hematological malignancies has increased markedly in the past decades. To examine the finescale details of how this progress has occurred, we carried out KaplanMeier causespecific s...Survival of patients with childhood hematological malignancies has increased markedly in the past decades. To examine the finescale details of how this progress has occurred, we carried out KaplanMeier causespecific survival analysis using the Surveillance Epi demiology and End Results （SEER） dataset for patients with childhood hematologi cal malignancies Hodgkin＇s Lymphoma, NonHodgkin＇s Lymphoma, Lymphoblastic Leukemia and Myeloid Leukemia diagnosed in five eras： 1983-1987; 1988-1992; 1993-1997; 1998-2002 and 2003-2007. We generated KaplanMeier estimates of survival for each of the first 24 years after diagnosis. These figures agree with previously reported five and tenyear values and attest to the remarkable increase in survival that has occurred over the past three decades of medical progress. The trend towards progres sively increasing survival shows no sign of slowing, suggesting that we may expect further increases in survival in the years ahead. Most of the increase in survival for childhood hematological malignancies has occurred by reducing the risk of death in the first two years after diagnosis. This may be largely explained by the fact that this is the time period when patients are at highest risk of death.展开更多
文摘AIM: To describe survival trends in patients in Northeast China diagnosed as gastric cancer. METHODS: A review of all inpatient and outpatient records of gastric cancer patients was conducted in the First Affiliated Hospital of China Medical University. All the gastric cancer patients who satisfied the inclusion criteria from January 1, 1980 through December 31, 2003 were included in the study. The main outcomes were based on median survival and 3-year and 5-year survival rates, by decade of diagnosis. RESULTS: From 1980 through 2003, the median survival for patients with gastric cancer (n = 1604) increased from 33 mo to 49 mo. The decade of diagnosis was not significantly associated with patient survival for gastric cancer (P = 0.084 for overall survival, and P = 0.150 for 5-year survival); however, the survival rate of the 2000s was remarkably higher than that of the 1980s (P = 0.019 for overall survival, and P = 0.027 for 5-year survival).CONCLUSION: There was no significant difference of survival among each period; however, the survival rate of the 2000s was remarkably higher than that of the 1980s.
基金supported partially by the National Central Cancer Registries of China(the Tumor Follow-up Registration Programs MF2008293,2009-193,and 2010-90)by the National Science and Technology Mega-Projects of China(2012ZX100020009-018 and 2012ZX10002-008)
文摘Background:There have been few reports on long-term survival of gastric cancer patients.This study analyzed the survival data of gastric cancer patients obtained from the population-based Qidong Cancer Registry between 1972 and 2011,providing a basis for evaluation of gastric cancer treatment and prognosis.Methods:The cumulative observed survival rate and relative survival rate of gastric cancer patients were calculated using Hakulinen's method via the SURV3.01 software,which was developed by the Finnish Cancer Registry.The date of the last follow-up for the survival status of the 15,401 registered cases was April 30,2012.Results:The 1-,5-,10-,20-,and 30-year observed survival rates were 33.82%,14.18%,10.35%,6.63%,and 4.19%,respectively,and the 1-,5-,10-,20-,and 30-year relative survival rates were 35.43%,18.13%,17.50%,21.96%,and32.84%,respectively.For males,the corresponding observed survival rates were 34.50%,14.40%,10.42%,6.46%,and4.05%,and the corresponding relative survival rates were 36.23%,18.67%,18.28%,23.73%,and 38.61%.For females,the corresponding observed survival rates were 32.62%,13.80%,10.22%,6.95%,and 4.46%,and the corresponding relative survival rates were 34.03%,17.21%,16.28%,19.70%,and 26.78%.Significant differences in relative survival rates were observed between sexes(P=0.003).For the 15-34,35-44,45-54,55-64,65-74,and 75+ age groups,the 5-year relative survival rates were 16.13%,21.77%,18.63%,12.61%,7.99%,and 2.94%,respectively,and the 10-year relative survival rates were 16.49%,22.83%,20.50%,15.97%,15.88%,and 15.73%,respectively.Remarkable improvement could be observed for the 5-,10-,and 15-year relative survival rates in Qidong beginning in the 1980 s.Conclusion:The survival outcome of registered gastric cancer cases in Qidong showed gradual progress over the past two decades.
文摘Survival of patients with childhood hematological malignancies has increased markedly in the past decades. To examine the finescale details of how this progress has occurred, we carried out KaplanMeier causespecific survival analysis using the Surveillance Epi demiology and End Results （SEER） dataset for patients with childhood hematologi cal malignancies Hodgkin＇s Lymphoma, NonHodgkin＇s Lymphoma, Lymphoblastic Leukemia and Myeloid Leukemia diagnosed in five eras： 1983-1987; 1988-1992; 1993-1997; 1998-2002 and 2003-2007. We generated KaplanMeier estimates of survival for each of the first 24 years after diagnosis. These figures agree with previously reported five and tenyear values and attest to the remarkable increase in survival that has occurred over the past three decades of medical progress. The trend towards progres sively increasing survival shows no sign of slowing, suggesting that we may expect further increases in survival in the years ahead. Most of the increase in survival for childhood hematological malignancies has occurred by reducing the risk of death in the first two years after diagnosis. This may be largely explained by the fact that this is the time period when patients are at highest risk of death.
