In view of the pressure time of emergency rescue against the infectious diseases,a mathematical model to optimize the location of emergency rescue centers is proposed.The model takes full account of the spread functio...In view of the pressure time of emergency rescue against the infectious diseases,a mathematical model to optimize the location of emergency rescue centers is proposed.The model takes full account of the spread function of infectious diseases,the cycle of pulse vaccination,the distance between the demand area and the emergency rescue centers,as well as the building and maintenance cost for the emergency rescue center,and so on.At the same time,the model integrates the traditional location selection models which are the biggest cover model,the p-center model and the p-median model,and it embodies the principles of fairness and efficiency for the emergency center location.Finally,a computation of an example arising from practice provides satisfactory results.展开更多
In this article, an SIRS epidemic model spread by vectors (mosquitoes) which have an incubation time to become infectious is formulated. It is shown that a disease-free equilibrium point is globally stable if no end...In this article, an SIRS epidemic model spread by vectors (mosquitoes) which have an incubation time to become infectious is formulated. It is shown that a disease-free equilibrium point is globally stable if no endemic equilibrium point exists. Further, the endemic equilibrium point (if it exists) is globally stable with a respect "weak delay". Some known results are generalized.展开更多
In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch in...In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch infection between different groups. As a result, we partially generalize the recent result in the article [16].展开更多
In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By u...In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By using strict monotonicity of the incidence function and constructing a Lyapunov functional, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. When the nonlinear inci- dence rate is a saturated incidence rate, our result provides a new global stability condition for a small rate of immunity loss.展开更多
The use of the SIR model to predict the time evolution of an epidemic is very frequent and has spatial information about its propagation which may be very useful to contrast its spread. In this paper we take a particu...The use of the SIR model to predict the time evolution of an epidemic is very frequent and has spatial information about its propagation which may be very useful to contrast its spread. In this paper we take a particular cellular automaton model that well reproduces the time evolution of the disease given by the SIR model;setting the automaton is generally an annoying problem because we need to run a lot of simulations, compare them to the solution of the SIR model and, finally, decide the parameters to use. In order to make this procedure easier, we will show a fast method that, in input, requires the parameters of the SIR continuous model that we want to reproduce, whereas, in output, it yields the parameters to use in the cellular automaton model. The problem of computing the most suitable parameters for the reticular model is reduced to the problem of finding the roots of a polynomial Equation.展开更多
The paper establishes two stochastic SIRS models with jumps to describe the spread of network virus by cyber war, terrorism and others. First, adding random perturbations proportionally to each variable, we get the dy...The paper establishes two stochastic SIRS models with jumps to describe the spread of network virus by cyber war, terrorism and others. First, adding random perturbations proportionally to each variable, we get the dynamic properties around the positive equilibrium of the deterministic model and the conditions for persistence and extinction. Second, giving a random disturbance to endemic equilibrium, we get a stochastic system with jumps. By modifying the existing Lyapunov function, we prove the positive solution of the system is stochastically stable.展开更多
A stochastic susceptible-infective-recovered-susceptible( SIRS) model with non-linear incidence and Levy jumps was considered. Under certain conditions, the SIRS had a global positive solution. The stochastically ulti...A stochastic susceptible-infective-recovered-susceptible( SIRS) model with non-linear incidence and Levy jumps was considered. Under certain conditions, the SIRS had a global positive solution. The stochastically ultimate boundedness of the solution of the model was obtained by using the method of Lyapunov function and the generalized Ito's formula. At last,asymptotic behaviors of the solution were discussed according to the value of R0. If R0< 1,the solution of the model oscillates around a steady state, which is the diseases free equilibrium of the corresponding deterministic model,and if R0> 1,it fluctuates around the endemic equilibrium of the deterministic model.展开更多
An SIR model of Zika virus (ZIKV) spread is formulated that includes ZIKV infections to newborns. Analytically, the model has one disease free and one endemic equilibrium point. The free one is stable for some conditi...An SIR model of Zika virus (ZIKV) spread is formulated that includes ZIKV infections to newborns. Analytically, the model has one disease free and one endemic equilibrium point. The free one is stable for some conditions when R0 and unstable when R0>1. In Brazil, when R0≈2>1 ZIKV infections expand and for R0 = 0.875R0) of the model. There are parameters for human-mosquito transmission and some for sexual-transmission factor. It appears that controlling spread of ZIKV infections by human-mosquito transmission may greatly reduce the value of R0.展开更多
This paper presents a new modified SIR model which incorporates appropriate delay parameters leading to a more precise prediction of COVID-19 real time data. The efficacy of the newly developed SIR model is proven by ...This paper presents a new modified SIR model which incorporates appropriate delay parameters leading to a more precise prediction of COVID-19 real time data. The efficacy of the newly developed SIR model is proven by comparing its predictions to real data obtained from four counties namely Germany, Italy, Kuwait, and Oman. Two included delay periods for incubation and recovery within the SIR model produce a sensible and more accurate representation of the real time data. In the absence of the two-delay period (<img src="Edit_8ce6d5c5-9b59-4640-9c0e-334e3948d11c.png" width="67" height="20" alt="" /><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">)</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> the dynamical behavior of the model will not correspond to today’s picture and lag the detection of the epidemic peak. The reproductive number <i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">R</span></i></span></span><span><span><span style="font-family:;" "=""><i><span style="font-family:Verdana;"><sub>0</sub></span></i><span style="font-family:Verdana;"></span></span></span></span></i> <span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">is defined for the model for values of recovery time delay <i></i></span></span></span><i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"><img src="Edit_882b068a-f7fa-478e-9fb9-4d78388010f3.png" width="25" height="20" alt="" /></span></i></span></span></i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sub></sub></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> of the infective case. The effect of recovery time <img src="Edit_882b068a-f7fa-478e-9fb9-4d78388010f3.png" width="25" height="20" alt="" /></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">may produce second wave, and/or an oscillation which could destabilize the behavior of the system and a periodic oscillation can arise due to Hopf bifurcation phenomenon.</span></span></span>展开更多
In this paper, a delayed SIR model with exponential demographic structure and the saturated incidence rate is formulated. The stability of the equilibria is analyzed with delay: the endemic equilibrium is locally stab...In this paper, a delayed SIR model with exponential demographic structure and the saturated incidence rate is formulated. The stability of the equilibria is analyzed with delay: the endemic equilibrium is locally stable without delay;and the endemic equilibrium is stable if the delay is under some condition. Moreover the dynamical behaviors from stability to instability will change with an appropriate?critical value. At last, some numerical simulations of the model are given to illustrate the main theoretical results.展开更多
This paper presents a restricted SIRmathematicalmodel to analyze the evolution of a contagious infectious disease outbreak(COVID-19)using available data.The new model focuses on two main concepts:first,it can present ...This paper presents a restricted SIRmathematicalmodel to analyze the evolution of a contagious infectious disease outbreak(COVID-19)using available data.The new model focuses on two main concepts:first,it can present multiple waves of the disease,and second,it analyzes how far an infection can be eradicated with the help of vaccination.The stability analysis of the equilibrium points for the suggested model is initially investigated by identifying the matching equilibrium points and examining their stability.The basic reproduction number is calculated,and the positivity of the solutions is established.Numerical simulations are performed to determine if it is multipeak and evaluate vaccination’s effects.In addition,the proposed model is compared to the literature already published and the effectiveness of vaccination has been recorded.展开更多
This paper is concerned with the spatial propagation of an SIR epidemic model with nonlocal diffusion and free boundaries describing the evolution of a disease.This model can be viewed as a nonlocal version of the fre...This paper is concerned with the spatial propagation of an SIR epidemic model with nonlocal diffusion and free boundaries describing the evolution of a disease.This model can be viewed as a nonlocal version of the free boundary problem studied by Kim et al.(An SIR epidemic model with free boundary.Nonlinear Anal RWA,2013,14:1992-2001).We first prove that this problem has a unique solution defined for all time,and then we give sufficient conditions for the disease vanishing and spreading.Our result shows that the disease will not spread if the basic reproduction number R_(0)<1,or the initial infected area h_(0),expanding ability μ and the initial datum S_(0) are all small enough when 1<R_(0)<1+d/μ_(2)+α.Furthermore,we show that if 1<R_(0)<1+d/μ_(2)+α,the disease will spread when h_(0) is large enough or h_(0) is small but μ is large enough.It is expected that the disease will always spread when R_(0)≥1+d/μ_(2)+α which is different from the local model.展开更多
In a polluted environment, considering the biological population infected with a kind of disease and hunted by human beings, we formulate a nonautonomous SIR population-epidemic model with time-varying impulsive relea...In a polluted environment, considering the biological population infected with a kind of disease and hunted by human beings, we formulate a nonautonomous SIR population-epidemic model with time-varying impulsive release and general nonlinear incidence rate and investigate dynamical behaviors of the model. Under the reasonable assumptions, the sufficient conditions which guarantee the globally attractive of the disease-free periodic solution and the permanence of the infected fish are established, that is, the infected fish dies out if , whereas the disease persists if . To substantiate our theoretical results, extensive numerical simulations are performed for a hypothetical set of parameter values.展开更多
In this paper, we investigate the dynamic properties of an SIR epidemic model with saturated growth rate. Under the conditions of an arbitrary initial value, we prove that the system exists unique positive solution, a...In this paper, we investigate the dynamic properties of an SIR epidemic model with saturated growth rate. Under the conditions of an arbitrary initial value, we prove that the system exists unique positive solution, and give the sufficient conditions caused by random environmental factors leading to the extinction of infectious diseases. Moreover, we verify the conditions for the persistence of infectious diseases in the mean sense. Finally, we provide the biology interpretation and some strategies to control the infectious diseases.展开更多
This paper is concerned with a delayed SIRS epidemic model with a nonlinear incidence rate. The main results are given in terms of local stability and Hopf bifurcation. Sufficient conditions for the local stability of...This paper is concerned with a delayed SIRS epidemic model with a nonlinear incidence rate. The main results are given in terms of local stability and Hopf bifurcation. Sufficient conditions for the local stability of the positive equilibrium and existence of Hopf bifurcation are obtained by regarding the time delay as the bifurcation parameter. Further,the properties of Hopf bifurcation such as the direction and stability are investigated by using the normal form theory and center manifold argument. Finally,some numerical simulations are presented to verify the theoretical analysis.展开更多
A stochastic susceptible-infective-recovered(SIR)epidemic model with jumps was considered.The contributions of this paper are as follows.(1) The stochastic differential equation(SDE)associated with the model has a uni...A stochastic susceptible-infective-recovered(SIR)epidemic model with jumps was considered.The contributions of this paper are as follows.(1) The stochastic differential equation(SDE)associated with the model has a unique global positive solution;(2) the results reveal that the solution of this epidemic model will be stochastically ultimately bounded,and the non-linear SDE admits a unique stationary distribution under certain parametric conditions;(3) the coefficients play an important role in the extinction of the diseases.展开更多
In this paper, we propose random fluctuation on contact and recovery rates in deterministic SIR model with disease deaths in nonparametric manner and derive a new stochastic SIR model with distributed time delay and g...In this paper, we propose random fluctuation on contact and recovery rates in deterministic SIR model with disease deaths in nonparametric manner and derive a new stochastic SIR model with distributed time delay and general diffusion coefficients. By analysis of the introduced model, we obtain the sufficient conditions for the regularity, existence and uniqueness of a global solution by means of Lyapunov function. Moreover, we also investigate the stochastic asymptotic stability of disease free equilibria and endemic equilibria of this model. Finally, we illustrate our general results by applications.展开更多
基金The National Natural Science Foundation of China(No.70671021)the National Key Technology R&D Program of China during the 11th Five-Year Plan Period(No.2006BAH02A06)
文摘In view of the pressure time of emergency rescue against the infectious diseases,a mathematical model to optimize the location of emergency rescue centers is proposed.The model takes full account of the spread function of infectious diseases,the cycle of pulse vaccination,the distance between the demand area and the emergency rescue centers,as well as the building and maintenance cost for the emergency rescue center,and so on.At the same time,the model integrates the traditional location selection models which are the biggest cover model,the p-center model and the p-median model,and it embodies the principles of fairness and efficiency for the emergency center location.Finally,a computation of an example arising from practice provides satisfactory results.
基金This work is supported by the National Sciences Foundation of China (10471040)the Youth Science Foundations of Shanxi Province (20021003).
文摘In this article, an SIRS epidemic model spread by vectors (mosquitoes) which have an incubation time to become infectious is formulated. It is shown that a disease-free equilibrium point is globally stable if no endemic equilibrium point exists. Further, the endemic equilibrium point (if it exists) is globally stable with a respect "weak delay". Some known results are generalized.
基金supported by Japan Society for the Promotion of Science (Grant Scientific Research (c), No. 24540219 to the first author, JSPS Fellows, No.237213 to the second author, and No. 222176 to the third author)
文摘In this article, we establish the global stability of an endemic equilibrium of multi-group SIR epidemic models, which have not only an exchange of individuals between patches through migration but also cross patch infection between different groups. As a result, we partially generalize the recent result in the article [16].
基金supported in part by JSPS Fellows,No.237213 of Japan Society for the Promotion of Science to the first authorthe Grant MTM2010-18318 of the MICINN,Spanish Ministry of Science and Innovation to the second authorScientific Research (c),No.21540230 of Japan Society for the Promotion of Science to the third author
文摘In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By using strict monotonicity of the incidence function and constructing a Lyapunov functional, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. When the nonlinear inci- dence rate is a saturated incidence rate, our result provides a new global stability condition for a small rate of immunity loss.
文摘The use of the SIR model to predict the time evolution of an epidemic is very frequent and has spatial information about its propagation which may be very useful to contrast its spread. In this paper we take a particular cellular automaton model that well reproduces the time evolution of the disease given by the SIR model;setting the automaton is generally an annoying problem because we need to run a lot of simulations, compare them to the solution of the SIR model and, finally, decide the parameters to use. In order to make this procedure easier, we will show a fast method that, in input, requires the parameters of the SIR continuous model that we want to reproduce, whereas, in output, it yields the parameters to use in the cellular automaton model. The problem of computing the most suitable parameters for the reticular model is reduced to the problem of finding the roots of a polynomial Equation.
基金partially supported by the Natural Science Foundation of Heilongjiang Province(A201420)Educational Reform Project of Heilongjiang Province(JG2013010482)+1 种基金Foundation of Heilongjiang Province Educational Committee(12541696)the Natural Science Foundation of China(11401136,11301112,11301207,11501148)
文摘The paper establishes two stochastic SIRS models with jumps to describe the spread of network virus by cyber war, terrorism and others. First, adding random perturbations proportionally to each variable, we get the dynamic properties around the positive equilibrium of the deterministic model and the conditions for persistence and extinction. Second, giving a random disturbance to endemic equilibrium, we get a stochastic system with jumps. By modifying the existing Lyapunov function, we prove the positive solution of the system is stochastically stable.
基金National Natural Science Foundations of China(No.11071259,No.11371374)Research Fund for the Doctoral Program of Higher Education of China(No.20110162110060)
文摘A stochastic susceptible-infective-recovered-susceptible( SIRS) model with non-linear incidence and Levy jumps was considered. Under certain conditions, the SIRS had a global positive solution. The stochastically ultimate boundedness of the solution of the model was obtained by using the method of Lyapunov function and the generalized Ito's formula. At last,asymptotic behaviors of the solution were discussed according to the value of R0. If R0< 1,the solution of the model oscillates around a steady state, which is the diseases free equilibrium of the corresponding deterministic model,and if R0> 1,it fluctuates around the endemic equilibrium of the deterministic model.
文摘An SIR model of Zika virus (ZIKV) spread is formulated that includes ZIKV infections to newborns. Analytically, the model has one disease free and one endemic equilibrium point. The free one is stable for some conditions when R0 and unstable when R0>1. In Brazil, when R0≈2>1 ZIKV infections expand and for R0 = 0.875R0) of the model. There are parameters for human-mosquito transmission and some for sexual-transmission factor. It appears that controlling spread of ZIKV infections by human-mosquito transmission may greatly reduce the value of R0.
文摘This paper presents a new modified SIR model which incorporates appropriate delay parameters leading to a more precise prediction of COVID-19 real time data. The efficacy of the newly developed SIR model is proven by comparing its predictions to real data obtained from four counties namely Germany, Italy, Kuwait, and Oman. Two included delay periods for incubation and recovery within the SIR model produce a sensible and more accurate representation of the real time data. In the absence of the two-delay period (<img src="Edit_8ce6d5c5-9b59-4640-9c0e-334e3948d11c.png" width="67" height="20" alt="" /><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">)</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> the dynamical behavior of the model will not correspond to today’s picture and lag the detection of the epidemic peak. The reproductive number <i></i></span></span></span><i><span><span><i><span style="font-family:Verdana;">R</span></i></span></span><span><span><span style="font-family:;" "=""><i><span style="font-family:Verdana;"><sub>0</sub></span></i><span style="font-family:Verdana;"></span></span></span></span></i> <span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">is defined for the model for values of recovery time delay <i></i></span></span></span><i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"><img src="Edit_882b068a-f7fa-478e-9fb9-4d78388010f3.png" width="25" height="20" alt="" /></span></i></span></span></i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sub></sub></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> of the infective case. The effect of recovery time <img src="Edit_882b068a-f7fa-478e-9fb9-4d78388010f3.png" width="25" height="20" alt="" /></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">may produce second wave, and/or an oscillation which could destabilize the behavior of the system and a periodic oscillation can arise due to Hopf bifurcation phenomenon.</span></span></span>
文摘In this paper, a delayed SIR model with exponential demographic structure and the saturated incidence rate is formulated. The stability of the equilibria is analyzed with delay: the endemic equilibrium is locally stable without delay;and the endemic equilibrium is stable if the delay is under some condition. Moreover the dynamical behaviors from stability to instability will change with an appropriate?critical value. At last, some numerical simulations of the model are given to illustrate the main theoretical results.
基金Research Partnership Program no.RP-21-09-06 from the Deanship of Scientific Research of Imam Mohammad Ibn Saud Islamic University(IMSIU).
文摘This paper presents a restricted SIRmathematicalmodel to analyze the evolution of a contagious infectious disease outbreak(COVID-19)using available data.The new model focuses on two main concepts:first,it can present multiple waves of the disease,and second,it analyzes how far an infection can be eradicated with the help of vaccination.The stability analysis of the equilibrium points for the suggested model is initially investigated by identifying the matching equilibrium points and examining their stability.The basic reproduction number is calculated,and the positivity of the solutions is established.Numerical simulations are performed to determine if it is multipeak and evaluate vaccination’s effects.In addition,the proposed model is compared to the literature already published and the effectiveness of vaccination has been recorded.
基金Zhao was supported by a scholarship from the China Scholarship Council,Li was partially supported by NSF of China(11731005)Cao was partially supported by NSF of China(11901264).
文摘This paper is concerned with the spatial propagation of an SIR epidemic model with nonlocal diffusion and free boundaries describing the evolution of a disease.This model can be viewed as a nonlocal version of the free boundary problem studied by Kim et al.(An SIR epidemic model with free boundary.Nonlinear Anal RWA,2013,14:1992-2001).We first prove that this problem has a unique solution defined for all time,and then we give sufficient conditions for the disease vanishing and spreading.Our result shows that the disease will not spread if the basic reproduction number R_(0)<1,or the initial infected area h_(0),expanding ability μ and the initial datum S_(0) are all small enough when 1<R_(0)<1+d/μ_(2)+α.Furthermore,we show that if 1<R_(0)<1+d/μ_(2)+α,the disease will spread when h_(0) is large enough or h_(0) is small but μ is large enough.It is expected that the disease will always spread when R_(0)≥1+d/μ_(2)+α which is different from the local model.
文摘In a polluted environment, considering the biological population infected with a kind of disease and hunted by human beings, we formulate a nonautonomous SIR population-epidemic model with time-varying impulsive release and general nonlinear incidence rate and investigate dynamical behaviors of the model. Under the reasonable assumptions, the sufficient conditions which guarantee the globally attractive of the disease-free periodic solution and the permanence of the infected fish are established, that is, the infected fish dies out if , whereas the disease persists if . To substantiate our theoretical results, extensive numerical simulations are performed for a hypothetical set of parameter values.
文摘In this paper, we investigate the dynamic properties of an SIR epidemic model with saturated growth rate. Under the conditions of an arbitrary initial value, we prove that the system exists unique positive solution, and give the sufficient conditions caused by random environmental factors leading to the extinction of infectious diseases. Moreover, we verify the conditions for the persistence of infectious diseases in the mean sense. Finally, we provide the biology interpretation and some strategies to control the infectious diseases.
基金National Natural Science Foundation of China(No.61273070)the Priority Academic Program Development of Jiangsu Higher Education Institutions,China
文摘This paper is concerned with a delayed SIRS epidemic model with a nonlinear incidence rate. The main results are given in terms of local stability and Hopf bifurcation. Sufficient conditions for the local stability of the positive equilibrium and existence of Hopf bifurcation are obtained by regarding the time delay as the bifurcation parameter. Further,the properties of Hopf bifurcation such as the direction and stability are investigated by using the normal form theory and center manifold argument. Finally,some numerical simulations are presented to verify the theoretical analysis.
基金Natural Science Foundation of Hunan University of Technology,China(No.2012HZX08)the Special Foundation of National Independent Innovation Demonstration Area Construction of Zhuzhou(Applied Basic Research),China
文摘A stochastic susceptible-infective-recovered(SIR)epidemic model with jumps was considered.The contributions of this paper are as follows.(1) The stochastic differential equation(SDE)associated with the model has a unique global positive solution;(2) the results reveal that the solution of this epidemic model will be stochastically ultimately bounded,and the non-linear SDE admits a unique stationary distribution under certain parametric conditions;(3) the coefficients play an important role in the extinction of the diseases.
文摘In this paper, we propose random fluctuation on contact and recovery rates in deterministic SIR model with disease deaths in nonparametric manner and derive a new stochastic SIR model with distributed time delay and general diffusion coefficients. By analysis of the introduced model, we obtain the sufficient conditions for the regularity, existence and uniqueness of a global solution by means of Lyapunov function. Moreover, we also investigate the stochastic asymptotic stability of disease free equilibria and endemic equilibria of this model. Finally, we illustrate our general results by applications.