AIM：To present a novel scleral flap suturing technique for filtering glaucoma surgery in order to control high postoperative intraocular pressure（IOP）.METHODS：Description of ‘the accordion suture＇ technique for ...AIM：To present a novel scleral flap suturing technique for filtering glaucoma surgery in order to control high postoperative intraocular pressure（IOP）.METHODS：Description of ‘the accordion suture＇ technique for mitomycin C augmented trabeculectomy.In cases of postoperative high IOP,pulling the loop of the suture helps to lift up the scleral flap by an even pressure on both edges.By means of this technique,the scleral flap opens up in an ‘‘accordion＇＇ manner,thus preventing flap obstruction and providing adequate aqueous flow.RESULTS：Our study group consisted of 8 eyes of 8 patients with neovascular glaucoma.Mean age of the subjects was 67.42±8.21 y and female/male ratio was 4/4.Mean preoperative IOP was 37±7.48 mm Hg.Mitomycin C augmented trabeculectomy was carried out on the subjects without any complications.The scleral flap closure is performed with three separate sutures;initially,our accordion suture through the center of the flap,and two releasable sutures on both corners.All the patients received removal of two side releasable sutures concomitant with pulling the accordion suture,without any complications.The average traction time was 3.5±0 wk postoperatively.The mean postoperative IOP was 11.37±2.72 mm Hg.No suture related complications were observed.CONCLUSION：This technique can be the suture of choice for filtering glaucoma surgery in experienced hands by its easy learning curve for precisely indicated patients.展开更多
Because of good clinical performance and low cost,silk braided surgical suture becomes one of excellent and widely used sutures. But as a kind of natural protein fiber,silk easily trends to microbial infection. Beyond...Because of good clinical performance and low cost,silk braided surgical suture becomes one of excellent and widely used sutures. But as a kind of natural protein fiber,silk easily trends to microbial infection. Beyond that,braided structure may increase the risk of hide of bacteria. Hence,the project of this study is to develop a novel antibacterial silk braided suture. Silk braided sutures were treated with antimicrobial solution which added antimicrobial agent4-quinolones into 5% polycaprolactone( PCL) solution. Then sutures were tested for in vitro efficacy against Staphylococcus aureus(S. aureus) and Escherichia coli(E. coli) by a zone of inhibition assay,and sustained efficacy assay,release of antibacterial agent,SEM photographs against S. aureus. Treated sutures exhibited distinct zones of inhibition against S. aureus and E. coli. They also kept antimicrobial property against S. aureus for 7 d,which were almost equal with coated VICRYL*Plus sutures. The highest release concentration of treated suture was 1. 53 mg /L,which was lower than Cmaxof 4-quinolones,proved the safety of antibacterial silk suture. SEM photographs gave both the change of the surface and different bacteria growth situations on the surface before and after treating.展开更多
我国煤层渗透率低且地质条件复杂,采用常规油气储层改造的开发方式难度大、技术适应性差。近年来,基于应力释放的煤层气改造新方法“煤层气水平井水力喷射造穴”很好地解决了这一技术瓶颈问题,但是造穴卸压—增渗的作用机制及其主控地...我国煤层渗透率低且地质条件复杂,采用常规油气储层改造的开发方式难度大、技术适应性差。近年来,基于应力释放的煤层气改造新方法“煤层气水平井水力喷射造穴”很好地解决了这一技术瓶颈问题,但是造穴卸压—增渗的作用机制及其主控地质因素尚不明晰。为此,考虑了煤岩层理和天然裂隙的影响,采用有限元—离散元耦合方法(Finite-Discrete Element Method,FDEM)建立了煤层气水平井扇形洞穴完井数值模型,探究了造穴后岩体的应力演化历程和储层的卸压—增渗机制,并对比分析了不同储层参数(孔隙压缩系数、储层强度、弱面强度和地应力场)对应力释放的影响规律。研究结果表明:(1)围岩演化过程为造穴后岩体收缩,储层发生应力重构,围岩强度逐渐降低,岩体内部发生新生裂隙萌生和原生裂隙扩展,形成开挖损伤区和应力释放区;(2)参数敏感性分析表明孔隙压缩系数是决定造穴完井储层适应性的关键,弱面强度、储层强度和地应力场分布决定了围岩的应力演化模式和裂缝扩展形态;(3)造穴卸压后储层增渗机制为穴周裂缝提升导流能力,储层应力释放提升基质渗透率。结论认为,模型首次综合考虑了地层特点、造穴过程和煤岩裂隙的影响,研究结果揭示了煤层造穴后的应力演化过程及其卸压、增渗作用机制,深化了对煤层气水平井洞穴完井增产机理的认识,对我国煤层储层改造具有重要的工程参考价值。展开更多
文摘AIM：To present a novel scleral flap suturing technique for filtering glaucoma surgery in order to control high postoperative intraocular pressure（IOP）.METHODS：Description of ‘the accordion suture＇ technique for mitomycin C augmented trabeculectomy.In cases of postoperative high IOP,pulling the loop of the suture helps to lift up the scleral flap by an even pressure on both edges.By means of this technique,the scleral flap opens up in an ‘‘accordion＇＇ manner,thus preventing flap obstruction and providing adequate aqueous flow.RESULTS：Our study group consisted of 8 eyes of 8 patients with neovascular glaucoma.Mean age of the subjects was 67.42±8.21 y and female/male ratio was 4/4.Mean preoperative IOP was 37±7.48 mm Hg.Mitomycin C augmented trabeculectomy was carried out on the subjects without any complications.The scleral flap closure is performed with three separate sutures;initially,our accordion suture through the center of the flap,and two releasable sutures on both corners.All the patients received removal of two side releasable sutures concomitant with pulling the accordion suture,without any complications.The average traction time was 3.5±0 wk postoperatively.The mean postoperative IOP was 11.37±2.72 mm Hg.No suture related complications were observed.CONCLUSION：This technique can be the suture of choice for filtering glaucoma surgery in experienced hands by its easy learning curve for precisely indicated patients.
文摘Because of good clinical performance and low cost,silk braided surgical suture becomes one of excellent and widely used sutures. But as a kind of natural protein fiber,silk easily trends to microbial infection. Beyond that,braided structure may increase the risk of hide of bacteria. Hence,the project of this study is to develop a novel antibacterial silk braided suture. Silk braided sutures were treated with antimicrobial solution which added antimicrobial agent4-quinolones into 5% polycaprolactone( PCL) solution. Then sutures were tested for in vitro efficacy against Staphylococcus aureus(S. aureus) and Escherichia coli(E. coli) by a zone of inhibition assay,and sustained efficacy assay,release of antibacterial agent,SEM photographs against S. aureus. Treated sutures exhibited distinct zones of inhibition against S. aureus and E. coli. They also kept antimicrobial property against S. aureus for 7 d,which were almost equal with coated VICRYL*Plus sutures. The highest release concentration of treated suture was 1. 53 mg /L,which was lower than Cmaxof 4-quinolones,proved the safety of antibacterial silk suture. SEM photographs gave both the change of the surface and different bacteria growth situations on the surface before and after treating.
文摘我国煤层渗透率低且地质条件复杂,采用常规油气储层改造的开发方式难度大、技术适应性差。近年来,基于应力释放的煤层气改造新方法“煤层气水平井水力喷射造穴”很好地解决了这一技术瓶颈问题,但是造穴卸压—增渗的作用机制及其主控地质因素尚不明晰。为此,考虑了煤岩层理和天然裂隙的影响,采用有限元—离散元耦合方法(Finite-Discrete Element Method,FDEM)建立了煤层气水平井扇形洞穴完井数值模型,探究了造穴后岩体的应力演化历程和储层的卸压—增渗机制,并对比分析了不同储层参数(孔隙压缩系数、储层强度、弱面强度和地应力场)对应力释放的影响规律。研究结果表明:(1)围岩演化过程为造穴后岩体收缩,储层发生应力重构,围岩强度逐渐降低,岩体内部发生新生裂隙萌生和原生裂隙扩展,形成开挖损伤区和应力释放区;(2)参数敏感性分析表明孔隙压缩系数是决定造穴完井储层适应性的关键,弱面强度、储层强度和地应力场分布决定了围岩的应力演化模式和裂缝扩展形态;(3)造穴卸压后储层增渗机制为穴周裂缝提升导流能力,储层应力释放提升基质渗透率。结论认为,模型首次综合考虑了地层特点、造穴过程和煤岩裂隙的影响,研究结果揭示了煤层造穴后的应力演化过程及其卸压、增渗作用机制,深化了对煤层气水平井洞穴完井增产机理的认识,对我国煤层储层改造具有重要的工程参考价值。
