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Analysis of Switching Overvoltage in Regional Grid with Small Hydropower Plants
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作者 Juan Chen Haifeng Li 《Engineering(科研)》 2013年第9期19-23,共5页
Present-day small hydropower plants (SHPs) have a large development potential because of the increasing interest in renewable resources and distributed energy generation, therefore, there are many SHPs in places of Ch... Present-day small hydropower plants (SHPs) have a large development potential because of the increasing interest in renewable resources and distributed energy generation, therefore, there are many SHPs in places of China where are rich in water resources. However, it has caused overvoltages in the distribution network, and which is even worse for the switching overvoltage such as isolated network operation, changing power supply path. The simple network model is used to analyze the reasons of the switching overvoltage, and the simulation software DIgSILENT/PowerFactory is used to check out the results of the theoretical analysis. 展开更多
关键词 Small HYDROPOWER ISOLATED Operation CHANGING Power Supply PATH switching overVOLTAGE
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Effect of Different Arresters on Switching Overvoltages in UHV Transmission Lines
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作者 杨鹏程 陈水明 何金良 《Tsinghua Science and Technology》 SCIE EI CAS 2010年第3期325-328,共4页
The amplitude of switching overvoltages is a key factor for designing the insulation of UHV equipment. The effect of different arresters needs to be studied, since installing arresters is an important way to suppress ... The amplitude of switching overvoltages is a key factor for designing the insulation of UHV equipment. The effect of different arresters needs to be studied, since installing arresters is an important way to suppress switching overvoltages in UHV transmission lines. Switching overvoltages on the 1000 kV Huainan-Huxi double-circuit transmission line were simulated for different operating modes and different arrester designs using the electromagnetic transient program PSCAD/EMTDC. With parallel resistors, the switching overvoltages are less than 1.70 p.u. (1.0 p.u.=1100×√ 2 /√3 kV). If the arrestors are better, the switching overvoltages can be reduced even lower to 1.55 p.u. Without parallel resistors, the arresters can reduce three-phase energizing overvoltages to 1.70 p.u, while the single-phase reclosing overvoltages still exceed the limit. The results show that the parallel resistors cannot be eliminated if the arresters are only installed at each end of the transmission line. Also, better quality arresters significantly lower the switching overvoltages. 展开更多
关键词 UHV double-circuit transmission line switching overvoltages ARRESTERS
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Transitional Recovery Voltages at Capacitive Currents Switching-off by Vacuum and SF6 Circuit-Breakers
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作者 Tahir M. Lazimov Samir V. Imanov Esam A. Saafan 《Journal of Energy and Power Engineering》 2012年第5期777-783,共7页
Results of calculation the recovery voltages conditioned by capacitive currents switching-off by high voltage vacuum and auto-compression (SF6) circuit-breakers are presented in the article. The purpose of research ... Results of calculation the recovery voltages conditioned by capacitive currents switching-off by high voltage vacuum and auto-compression (SF6) circuit-breakers are presented in the article. The purpose of research was evaluating the maximum values of recovery voltages and also studying the dependence of recovery voltages on some influencing factors, especially on type of circuit-breaker presented in numerical models with its dielectric strength restoration law, chopping current and operation time. The research was carried out with using computer simulation. 展开更多
关键词 Recovery voltages capacitive currents switching overvoltages capacitor banks dielectric strength restoration law.
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Wedge-shaped HfO_(2) buffer layer-induced field-free spin-orbit torque switching of HfO_(2)/Pt/Co structure 被引量:1
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作者 陈建辉 梁梦凡 +4 位作者 宋衍 袁俊杰 张梦旸 骆泳铭 王宁宁 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期662-667,共6页
Field-free spin-orbit torque(SOT)switching of perpendicular magnetization is essential for future spintronic devices.This study demonstrates the field-free switching of perpendicular magnetization in an HfO_(2)/Pt/Co/... Field-free spin-orbit torque(SOT)switching of perpendicular magnetization is essential for future spintronic devices.This study demonstrates the field-free switching of perpendicular magnetization in an HfO_(2)/Pt/Co/TaO_(x) structure,which is facilitated by a wedge-shaped HfO_(2)buffer layer.The field-free switching ratio varies with HfO_(2)thickness,reaching optimal performance at 25 nm.This phenomenon is attributed to the lateral anisotropy gradient of the Co layer,which is induced by the wedge-shaped HfO_(2)buffer layer.The thickness gradient of HfO_(2)along the wedge creates a corresponding lateral anisotropy gradient in the Co layer,correlating with the switching ratio.These findings indicate that field-free SOT switching can be achieved through designing buffer layer,offering a novel approach to innovating spin-orbit device. 展开更多
关键词 spin-orbit torque field-free switching HfO_(2) buffer layer
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Large and Recoverable Electrostrain in Strained Ferroelectric Superlattices due to Domain Switching
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作者 JIANG Zhexin WANG Jie 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2021年第1期75-83,共9页
The ferroelectric superlattices have been widely studied due to their distinguished electromechanical coupling properties.Under different biaxial mismatch strains,ferroelectric superlattices exhibit different domain s... The ferroelectric superlattices have been widely studied due to their distinguished electromechanical coupling properties.Under different biaxial mismatch strains,ferroelectric superlattices exhibit different domain structures and electromechanical coupling properties.A three-dimensional phase field model is employed to investigate the detailed domain evolution and electromechanical properties of the PbTiO_(3)/SrTiO_(3)(PTO/STO)superlattices with different biaxial mismatch strains.The phase field simulations show that the ferroelectric superlattice exhibits large electrostrain in the stacking direction when an external field is applied.Under a large compressive mismatch strain,vortex domains appear in ferroelectric layers with the thickness of 4 nm.The vortex domains become stable cdomain under a large external electric field,which remains when the electric field is removed.When the initial compressive mismatch strain decreases gradually,the waved or a1/a2 domains replaces the initial vortex domains in the absence of electric field.The fully polarized c-domain by a large electric field switches to diagonal direction domain or a/c domain when the electric field is small.Furthermore,when a biaxial tensile strain is applied to the superlattice,ferroelectric domains switch back to the initial a1/a2 twin-like domain structure,resulting in the recoverable and large electrostrain.This provides an effective way to obtain the large and recoverable electrostrain for the engineering application. 展开更多
关键词 large electrostrain ferroelectric superlattices domain switching recoverable domains
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A Novel Switching Architecture for IP Over WDM Networks
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作者 王勇 《High Technology Letters》 EI CAS 2001年第3期25-28,共4页
Integrating IP and WDM is an attractive direction for research. Many solutions have been presented but it is noted that the existing switching technologies still need more concern. Since optical packet switching is no... Integrating IP and WDM is an attractive direction for research. Many solutions have been presented but it is noted that the existing switching technologies still need more concern. Since optical packet switching is not practical yet, there are just two possible solutions left. One is wavelength routing(WR), which is circuit switching in essence and the other is newly proposed optical burst switching (OBS). In this paper, characteristics of WR and OBS are first described, then, compared in several aspects. It is notice that in many aspects, the wavelength routing and burst switching are complement. This stimulates us to propose a new switching architecture, which may be considered as 'mixture' of WR and OBS. We believe the network built on new switching structure can accommodate the requirements of practicability, flexibility, robustness, efficiency and etc. simultaneously. However, many related problems still need to be further researched. 展开更多
关键词 IP over WDM Wavelength routing Optical burst switching
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Auditor Switching by Corporate Governance: Empirical Analysis From the Listed Company in China
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作者 Zhang Yanan Cheng Wen Ren Jinzheng 《Journal of Modern Accounting and Auditing》 2013年第2期230-238,共9页
As the most important institutional arrangement in modem corporate, corporate governance is playing an increasingly important role in Chinese market economy, and its effect to auditor change is also being increasingly... As the most important institutional arrangement in modem corporate, corporate governance is playing an increasingly important role in Chinese market economy, and its effect to auditor change is also being increasingly tapped in recent years. This paper summarizes the reason of auditor switching, especially the elements of corporate governance. Then by selecting the A-share listed companies in China as a sample, the authors use statistical test and logistic regression analysis to explore how the 15 factors of corporate governance which are based on the indicators of Nankai University evaluation system affect auditor switching. The results show that the largest proportion of shareholding, the proportion of independent directors, and board meetings which on behalf of the level of corporate governance, have a significant and negative correlation with auditor switching. The results also show that full disclosure, litigation, and arbitration which on behave of the level of corporate governance have a significant positive correlation with auditor switching. 展开更多
关键词 corporate governance auditor switching influence factors
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Switching Frequency Improvement of a High Speed on/off Valve Based on Pre-excitation Control Algorithm
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作者 Qi Zhong Xiaotian Li +4 位作者 Yongxin Mao Enguang Xu Tiwei Jia Yanbiao Li Huayong Yang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第4期94-106,共13页
The high-speed on/off valve(HSV)serves as the fundamental component responsible for generating discrete fluids within digital hydraulic systems.As the switching frequency of the HSV increases,the properties of the gen... The high-speed on/off valve(HSV)serves as the fundamental component responsible for generating discrete fluids within digital hydraulic systems.As the switching frequency of the HSV increases,the properties of the generated discrete fluid approach those of continuous fluids.Therefore,a higher frequency response characteristic of HSV is the key to ensure the control accuracy of digital hydraulic systems.However,the current research mainly focuses on its dynamic performance,but neglect its FRC.This paper presents a theoretical analysis demonstrating that the FRC of the HSV can be enhanced by minimizing its switching time.The maximum switching frequency(MSF)is mainly determined by opening dynamic performance when HSV operates with low switching duty ratio(SDR),whereas the closing dynamic performance limits the MSF when HSV operates with high SDR.Building upon these findings,the pre-excitation control algorithm(PECA)is proposed to reduce the switching time of the HSV,and consequently enhance its FRC.Experimental results demonstrate that PECA shortens the opening delay time of HSV by 1.12 ms,the closing delay time by 2.54 ms,and the closing moving time by 0.47 ms in comparison to the existing advanced control algorithms.As a result,a larger MSF of 417 Hz and a wider controllable SDR range from 20%to 70%were achieved at a switching frequency of 250 Hz.Thus,the proposed PFCA in this paper has been verified as an effective and promising approach for enhancing the control performance of digital hydraulic systems. 展开更多
关键词 High speed on/off valve switching frequency Pre-excitation Dynamic performance switching duty ratio
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Tunable Three-Wavelength Fiber Laser and Transient Switching between Three-Wavelength Soliton and Q-Switched Mode-Locked States
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作者 司志增 戴朝卿 刘威 《Chinese Physics Letters》 SCIE EI CAS CSCD 2024年第2期10-13,共4页
We report a passive mode-locked fiber laser that can realize single-wavelength tuning and multi-wavelength spacing tuning simultaneously.The tuning range is from 1528 nm–1560 nm,and up to three bands of soliton state... We report a passive mode-locked fiber laser that can realize single-wavelength tuning and multi-wavelength spacing tuning simultaneously.The tuning range is from 1528 nm–1560 nm,and up to three bands of soliton states can be output at the same time.These results are confirmed by a nonlinear Schrodinger equation model based on the split-step Fourier method.In addition,we reveal a way to transform the multi-wavelength soliton state into the Q-switched mode-locked state,which is period doubling.These results will promote the development of optical communication,optical sensing and multi-signal pulse emission. 展开更多
关键词 tuning switched switching
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Resistive switching behavior and mechanism of HfO_(x) films with large on/off ratio by structure design
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作者 黄香林 王英 +2 位作者 黄慧香 段理 郭婷婷 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期660-665,共6页
Different bilayer structures of HfO_(x)/Ti(TiO_(x)) are designed for hafnium-based memory to investigate the switching characteristics. The chemical states in the films and near the interface are characterized by x-ra... Different bilayer structures of HfO_(x)/Ti(TiO_(x)) are designed for hafnium-based memory to investigate the switching characteristics. The chemical states in the films and near the interface are characterized by x-ray photoelectron spectroscopy,and the oxygen vacancies are analyzed. Highly improved on/off ratio(~104) and much uniform switching parameters are observed for bilayer structures compared to single layer HfO_(x) sample, which can be attributed to the modulation of oxygen vacancies at the interface and better control of the growth of filaments. Furthermore, the reliability of the prepared samples is investigated. The carrier conduction behaviors of HfO_(x)-based samples can be attributed to the trapping and de-trapping process of oxygen vacancies and a filamentary model is proposed. In addition, the rupture of filaments during the reset process for the bilayer structures occur at the weak points near the interface by the recovery of oxygen vacancies accompanied by the variation of barrier height. The re-formation of fixed filaments due to the residual filaments as lightning rods results in the better switching performance of the bilayer structure. 展开更多
关键词 HfO_(x)film resistive switching structure design interface modulation
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Review of Three-phase Soft Switching Inverters and Challenges for Motor Drives
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作者 Haifeng Lu Qiao Wang +1 位作者 Jianyun Chai Yongdong Li 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第2期177-190,共14页
For electric vehicles (EVs),it is necessary to improve endurance mileage by improving the efficiency.There exists a trend towards increasing the system voltage and switching frequency,contributing to improve charging ... For electric vehicles (EVs),it is necessary to improve endurance mileage by improving the efficiency.There exists a trend towards increasing the system voltage and switching frequency,contributing to improve charging speed and power density.However,this trend poses significant challenges for high-voltage and high-frequency motor controllers,which are plagued by increased switching losses and pronounced switching oscillations as consequences of hard switching.The deployment of soft switching technology presents a viable solution to mitigate these issues.This paper reviews the applications of soft switching technologies for three-phase inverters and classifies them based on distinct characteristics.For each type of inverter,the advantages and disadvantages are evaluated.Then,the paper introduces the research progress and control methods of soft switching inverters (SSIs).Moreover,it presents a comparative analysis among the conventional hard switching inverters (HSIs),an active clamping resonant DC link inverter (ACRDCLI) and an auxiliary resonant commuted pole inverter (ARCPI).Finally,the problems and prospects of soft switching technology applied to motor controllers for EVs are put forward. 展开更多
关键词 Soft switching inverters Zero-voltage switching Electric vehicles Motor drives
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Pure State Feedback Switching Control Based on the Online Estimated State for Stochastic Open Quantum Systems
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作者 Shuang Cong Zhixiang Dong 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第10期2166-2178,共13页
For the n-qubit stochastic open quantum systems,based on the Lyapunov stability theorem and LaSalle’s invariant set principle,a pure state switching control based on on-line estimated state feedback(short for OQST-SF... For the n-qubit stochastic open quantum systems,based on the Lyapunov stability theorem and LaSalle’s invariant set principle,a pure state switching control based on on-line estimated state feedback(short for OQST-SFC)is proposed to realize the state transition the pure state of the target state including eigenstate and superposition state.The proposed switching control consists of a constant control and a control law designed based on the Lyapunov method,in which the Lyapunov function is the state distance of the system.The constant control is used to drive the system state from an initial state to the convergence domain only containing the target state,and a Lyapunov-based control is used to make the state enter the convergence domain and then continue to converge to the target state.At the same time,the continuous weak measurement of quantum system and the quantum state tomography method based on the on-line alternating direction multiplier(QST-OADM)are used to obtain the system information and estimate the quantum state which is used as the input of the quantum system controller.Then,the pure state feedback switching control method based on the on-line estimated state feedback is realized in an n-qubit stochastic open quantum system.The complete derivation process of n-qubit QST-OADM algorithm is given;Through strict theoretical proof and analysis,the convergence conditions to ensure any initial state of the quantum system to converge the target pure state are given.The proposed control method is applied to a 2-qubit stochastic open quantum system for numerical simulation experiments.Four possible different position cases between the initial estimated state and that of the controlled system are studied and discussed,and the performances of the state transition under the corresponding cases are analyzed. 展开更多
关键词 Online state estimation state feedback control stochastic open quantum systems(OQST) switching control
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Single-atom catalysts based on polarization switching of ferroelectric In_(2)Se_(3) for N_(2) reduction
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作者 Nan Mu Tingting Bo +3 位作者 Yugao Hu Ruixin Xu Yanyu Liu Wei Zhou 《Chinese Journal of Catalysis》 SCIE CAS CSCD 2024年第8期244-257,共14页
The polarization switching plays a crucial role in controlling the final products in the catalytic pro-cess.The effect of polarization orientation on nitrogen reduction was investigated by anchoring transition metal a... The polarization switching plays a crucial role in controlling the final products in the catalytic pro-cess.The effect of polarization orientation on nitrogen reduction was investigated by anchoring transition metal atoms to form active centers on ferroelectric material In_(2)Se_(3).During the polariza-tion switching process,the difference in surface electrostatic potential leads to a redistribution of electronic states.This affects the interaction strength between the adsorbed small molecules and the catalyst substrate,thereby altering the reaction barrier.In addition,the surface states must be considered to prevent the adsorption of other small molecules(such as *O,*OH,and *H).Further-more,the V@↓-In_(2)Se_(3) possesses excellent catalytic properties,high electrochemical and thermody-namic stability,which facilitates the catalytic process.Machine learning also helps us further ex-plore the underlying mechanisms.The systematic investigation provides novel insights into the design and application of two-dimensional switchable ferroelectric catalysts for various chemical processes. 展开更多
关键词 In_(2)Se_(3) monolayer Density functional theory Ferroelectric switching Single atom catalysts Nitrogen reduction reaction Machine learning
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Machine-Learning Based Packet Switching Method for Providing Stable High-Quality Video Streaming in Multi-Stream Transmission
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作者 Yumin Jo Jongho Paik 《Computers, Materials & Continua》 SCIE EI 2024年第3期4153-4176,共24页
Broadcasting gateway equipment generally uses a method of simply switching to a spare input stream when a failure occurs in a main input stream.However,when the transmission environment is unstable,problems such as re... Broadcasting gateway equipment generally uses a method of simply switching to a spare input stream when a failure occurs in a main input stream.However,when the transmission environment is unstable,problems such as reduction in the lifespan of equipment due to frequent switching and interruption,delay,and stoppage of services may occur.Therefore,applying a machine learning(ML)method,which is possible to automatically judge and classify network-related service anomaly,and switch multi-input signals without dropping or changing signals by predicting or quickly determining the time of error occurrence for smooth stream switching when there are problems such as transmission errors,is required.In this paper,we propose an intelligent packet switching method based on the ML method of classification,which is one of the supervised learning methods,that presents the risk level of abnormal multi-stream occurring in broadcasting gateway equipment based on data.Furthermore,we subdivide the risk levels obtained from classification techniques into probabilities and then derive vectorized representative values for each attribute value of the collected input data and continuously update them.The obtained reference vector value is used for switching judgment through the cosine similarity value between input data obtained when a dangerous situation occurs.In the broadcasting gateway equipment to which the proposed method is applied,it is possible to perform more stable and smarter switching than before by solving problems of reliability and broadcasting accidents of the equipment and can maintain stable video streaming as well. 展开更多
关键词 Broadcasting and communication convergence multi-stream packet switching advanced television systems committee standard 3.0(ATSC 3.0) data pre-processing machine learning cosine similarity
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Chalcogenide Ovonic Threshold Switching Selector
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作者 Zihao Zhao Sergiu Clima +4 位作者 Daniele Garbin Robin Degraeve Geoffrey Pourtois Zhitang Song Min Zhu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第5期1-40,共40页
Today’s explosion of data urgently requires memory technologies capable of storing large volumes of data in shorter time frames,a feat unattain-able with Flash or DRAM.Intel Optane,commonly referred to as three-dimen... Today’s explosion of data urgently requires memory technologies capable of storing large volumes of data in shorter time frames,a feat unattain-able with Flash or DRAM.Intel Optane,commonly referred to as three-dimensional phase change memory,stands out as one of the most promising candidates.The Optane with cross-point architecture is constructed through layering a storage element and a selector known as the ovonic threshold switch(OTS).The OTS device,which employs chalcogenide film,has thereby gathered increased attention in recent years.In this paper,we begin by providing a brief introduction to the discovery process of the OTS phenomenon.Subsequently,we summarize the key elec-trical parameters of OTS devices and delve into recent explorations of OTS materials,which are categorized as Se-based,Te-based,and S-based material systems.Furthermore,we discuss various models for the OTS switching mechanism,including field-induced nucleation model,as well as several carrier injection models.Additionally,we review the progress and innovations in OTS mechanism research.Finally,we highlight the successful application of OTS devices in three-dimensional high-density memory and offer insights into their promising performance and extensive prospects in emerging applications,such as self-selecting memory and neuromorphic computing. 展开更多
关键词 Non-volatile memory Ovonic threshold switch(OTS) CHALCOGENIDE SELECTOR
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Model-free Speed Control of Single-phase Flux Switching Motor with an Asymmetrical Rotor
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作者 Zongsheng Zhang Congcong Guo 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第3期255-263,共9页
This paper proposes and implements a model-free open-loop iterative learning control(ILC)strategy to realize the speed control of the single-phase flux switching motor(FSM)with an asymmetrical rotor.Base on the propos... This paper proposes and implements a model-free open-loop iterative learning control(ILC)strategy to realize the speed control of the single-phase flux switching motor(FSM)with an asymmetrical rotor.Base on the proposed winding control method,the asymmetrical rotor enables the motor to generate continuous positive torque for positive rotation,and relatively small resistance torque for negative rotation.An initial iteration coefficient and variable iteration coefficient optimized scheme was proposed based on the characteristics of the hardware circuit,thereby forming the model-free strategy.A series of prototype experiments was carried out.Experimental results verify the effectiveness and practicability of the proposed ILC strategy. 展开更多
关键词 Asymmetrical rotor Model-free iterative control Prototype experiments Single-phase flux switching motor
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Physical Frame Time-Slot Switching-A New Switching Technique over DWDM
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作者 许登元 窦军 涂建平 《Journal of Electronic Science and Technology of China》 2005年第3期208-212,263,共6页
A novel technique called physical frame time-slot switching (PFTS) is discussed and its technical and application aspects are analyzed. The format of the ethernet media access control (MAC) frame is borrowed in de... A novel technique called physical frame time-slot switching (PFTS) is discussed and its technical and application aspects are analyzed. The format of the ethernet media access control (MAC) frame is borrowed in defining the physical frame for PFTS and the transmission time for the maximum size of the MAC frame is defined as a physical frame time-slot (PFT). Consequently, user data can be fed into PFTS and switched in a single layer sub-network in an asynchronous mode. 展开更多
关键词 physical frame time-slot switching three dimension ethernet MAN ethernet-like physical frame single user plane architecture
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First-Principles Study on Switching Performance and Spin Filtering Efficiency of Dimethyldihydropyrene/Cyclophanediene Single-Molecule Devices with Zigzag Graphene Nanoribbon Electrodes
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作者 Chang-Feng Zheng Yan-Qi Mu +1 位作者 Zong-Liang Li Guang-Ping Zhang 《Chinese Journal of Chemical Physics》 SCIE EI CAS CSCD 2024年第5期644-652,I0066-I0072,I0100,共17页
Moleculardeviceswith highswitchingperformance and/or the perfect spin filtering effect have always been the pursuit with the development of molecular electronics.Hereb,yusingthe 2001.0V nonequilibrium.Green's func... Moleculardeviceswith highswitchingperformance and/or the perfect spin filtering effect have always been the pursuit with the development of molecular electronics.Hereb,yusingthe 2001.0V nonequilibrium.Green's function method in combination with the density functionaltheory,the switching performance and spin filtering properties of dimethyldihydropyrene(DHP)/cyclophanediene(CPD)photoswitchable molecule connected by carbon atomic chains(CACs)to two zigzag graphene nanoribbon electrodes have been theoretically investigated.The results show that DHP is more conductive than CPD and therefore an evident switching effect is demonstrated,and the switching ratio(RON/OFF)can reach 4.5×103.It is further revealed that the RoON/OF of DHP/CPD closely depends on the length of CACs.More specifically,the RoN/OFF values of DHP/CPD with odd-numbered CACs are larger than those with even-numbered CACs.More interestingly,a high or even perfect spin filtering effect can be obtained in these investigated DHP/CPD single-molecule devices.Our study is helpful for future design of single-molecule switches and spin filters and provides a way to optimize their performance by means of varying the length of bridging CACs. 展开更多
关键词 Single-molecule switch Spin filtering effect Odd-even effect Nonequilibrium Green's function method Density functional theory
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Improvement of hepatic fibrosis after tenofovir disoproxil fumarate switching to tenofovir alafenamide for three years
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作者 Tung Huynh Delana MyAn Bui +1 位作者 Tina Xiwen Zhou Ke-Qin Hu 《World Journal of Hepatology》 2024年第7期1009-1017,共9页
BACKGROUND Both tenofovir alafenamide(TAF)and tenofovir disoproxil fumarate(TDF)are the first-line treatments for chronic hepatitis B(CHB).We have showed switching from TDF to TAF for 96 weeks resulted in further alan... BACKGROUND Both tenofovir alafenamide(TAF)and tenofovir disoproxil fumarate(TDF)are the first-line treatments for chronic hepatitis B(CHB).We have showed switching from TDF to TAF for 96 weeks resulted in further alanine aminotransferase(ALT)improvement,but data remain lacking on the long-term benefits of TDF switching to TAF on hepatic fibrosis.AIM To assess the benefits of TDF switching to TAF for 3 years on ALT,aspartate aminotransferase(AST),and hepatic fibrosis improvement in patients with CHB.METHODS A single center retrospective study on 53 patients with CHB who were initially treated with TDF,then switched to TAF to determine dynamic patterns of ALT,AST,AST to platelet ratio index(APRI),fibrosis-4(FIB-4)scores,and shear wave elastography(SWE)reading improvement at switching week 144,and the associated factors.RESULTS The mean age was 55(28-80);45.3%,males;15.1%,clinical cirrhosis;mean baseline ALT,24.8;AST,25.7 U/L;APRI,0.37;and FIB-4,1.66.After 144 weeks TDF switching to TAF,mean ALT and AST were reduced to 19.7 and 21,respectively.From baseline to switching week 144,the rates of ALT and AST<35(male)/25(female)and<30(male)/19(female)were persistently increased;hepatic fibrosis was also improved by APRI<0.5,from 79.2%to 96.2%;FIB-4<1.45,from 52.8%to 58.5%,respectively;mean APRI was reduced to 0.27;FIB-4,to 1.38;and mean SWE reading,from 7.05 to 6.30 kPa after a mean of 109 weeks switching.The renal function was stable and the frequency of patients with glomerular filtration rate>60 mL/min was increased from 86.5%at baseline to 88.2%at switching week 144.CONCLUSION Our data confirmed that switching from TDF to TAF for 3 years results in not only persistent ALT/AST improvement,but also hepatic fibrosis improvement by APRI,FIB-4 scores,as well as SWE reading,the important clinical benefits of long-term hepatitis B virus antiviral treatment with TAF. 展开更多
关键词 Tenofovir alafenamide Tenofovir disoproxil fumarate switching Hepatic fibrosis improvement Aspartate aminotransferase to platelet ratio index Fibrosis-4 Shear wave elastography
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Research on Switching Characteristics Based on Optimization Design of SiC MOSFET Drive Circuit
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作者 Wenjie Li Tianhu Wang +1 位作者 Jungang Wang Tailiang Yu 《Instrumentation》 2024年第2期64-71,共8页
With the increasing emphasis on energy conservation,emission reduction and environmental protection,the application prospect of SiC power devices is becoming more and more broad.In the high frequency application of Si... With the increasing emphasis on energy conservation,emission reduction and environmental protection,the application prospect of SiC power devices is becoming more and more broad.In the high frequency application of SiC MOSFET,the change rate of voltage and current in the turn-on and turn-off process increases with the increase of switching frequency.Also,the current and voltage spike oscillation phenomenon is gradually intensified due to the influence of circuit stray parameters.Based on the analysis of SiC MOSFET characteristics,the paper discusses the design requirements and design principles of SiC MOSFET drive circuit.Then,taking the SiC module C2M0080120D of Cree Company as an example,a driver circuit design is realized through the ACPL-355JC optocoupler driver module of Broadcom Company.The circuit not only has the characteristics of fast transmission delay and excellent performance,but also has the functions of overload and short circuit protection.The driving circuit is verified by LTspice simulation software,and the switching characteristics of SiC MOSFET under different working conditions are studied in depth.The experimental results show that the driving circuit can improve the switching time of SiC MOSFET and effectively solve the problem of current and voltage spike oscillation,which lays a foundation for the practical application of SiC MOSFET in the future. 展开更多
关键词 SiC MOSFET switching characteristic drive circuit LTspice
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