Description Cellular membranes present natural borders for signal transduction between cells and their environment. Nature developed different strategies to enable signals to cross the membrane barrier. The goal of th...Description Cellular membranes present natural borders for signal transduction between cells and their environment. Nature developed different strategies to enable signals to cross the membrane barrier. The goal of this meeting is to discuss the molecular mechanisms of transmembrane signaling on the basis of three protein classes, i.e.展开更多
Although the host response to tuberculosis has been studied for many years,we still have only a rudimentary working model of the disease process;namely that antigen-specific T cells activate infected macrophages to co...Although the host response to tuberculosis has been studied for many years,we still have only a rudimentary working model of the disease process;namely that antigen-specific T cells activate infected macrophages to control bacterial growth.Further progress in the control of tuberculosis will depend on a much more detailed understanding of the nature of the host response to infection.Therefore,the purpose of this Keystone Symposia meeting is to reassess our current understanding of disease mechanisms,discuss the展开更多
Recent data in both humans and non-human primates suggest that a clinically useful HIV-1 vaccine is possible and that the use of therapeutic interventions can be an efficacious prevention strategy.The path forward wil...Recent data in both humans and non-human primates suggest that a clinically useful HIV-1 vaccine is possible and that the use of therapeutic interventions can be an efficacious prevention strategy.The path forward will require a detailed understanding of the correlates of protection to HIV-1/SIV and the development of better immunogens to induce specific and long lasting immunity.Moreover,the role of vaccine elicited im-展开更多
文摘Description Cellular membranes present natural borders for signal transduction between cells and their environment. Nature developed different strategies to enable signals to cross the membrane barrier. The goal of this meeting is to discuss the molecular mechanisms of transmembrane signaling on the basis of three protein classes, i.e.
文摘Although the host response to tuberculosis has been studied for many years,we still have only a rudimentary working model of the disease process;namely that antigen-specific T cells activate infected macrophages to control bacterial growth.Further progress in the control of tuberculosis will depend on a much more detailed understanding of the nature of the host response to infection.Therefore,the purpose of this Keystone Symposia meeting is to reassess our current understanding of disease mechanisms,discuss the
文摘Recent data in both humans and non-human primates suggest that a clinically useful HIV-1 vaccine is possible and that the use of therapeutic interventions can be an efficacious prevention strategy.The path forward will require a detailed understanding of the correlates of protection to HIV-1/SIV and the development of better immunogens to induce specific and long lasting immunity.Moreover,the role of vaccine elicited im-
