Awareness about Early Detection Methods, Symptoms and Risk Factors towards Breast and Cervical Cancer among the Female Students of Mawlana Bhashani Science and Technology University (MBSTU), Santosh, Tangail, Bangladesh

The study was conducted to ensure knowledge, attitude, awareness about breast and cervical cancer among the female students of Mawlana Bhashani Science and Technology University. This study was carried out from July to September, 2015 among the participants of university female halls, different female hostels and different faculty of the university by using a validated questionnaire which was developed for this study. A total 250 female students, at the age of (18 - 26) years were participated. Collected information was analyzed using SPSS, Graph-pad Prism and MS Excel. The results showed that about 87.6% participants were undergraduate. Most of them come from village (45.6%) and city (36.0%). About 90% were Muslims and the socioeconomic level of most of the participants was middle (90.4%). In case of food intake patterns, it was observed that 35.6% participants eat chips, soft drinks, popcorn everyday;40.4% eat meat regularly;24% eat sugar everyday;27.6% eat fruits and vegetables every day. Among them, 55.6% girls maintained daily 1 hour physical activity;37.2% did exercise rarely;34.8% participants rarely do strenuous exercise. About 84.4% respondents have not any family history of cancer;6% participants have sister or mother having breast tumor and 7.2% have at least more than one close relative who have cancer. Among the participants, only 0.8% drank alcohol;1.2% have addiction of smoking cigarette;15.6% girls wear tight bra;3.6% have benign breast disease and 2.8% participants have attended in breast or cervical cancer screening programs. The moderate numbers of girls have breast cancer screening practice. Among them, only 28.8% participants have ever heard about BSE (Breast self-examination) and 40.4% have not any knowledge about breast cancer treatment. About 50.8% respondents don’t have any knowledge about cervical cancer treatment. The village people are the most risky group. About 17.02% girls recognized weakened immune system as a risk factor of cervical cancer. It can be concluded that, knowledge of participants regarding breast and cervical cancer is poor. Targeted education should be implemented to improve the knowledge of respondents about early detection methods and symptoms of breast and cervical cancer.

Identifying barriers to early diagnosis of breast cancer and perception of women in Malwa region of Punjab,India

Objective:The aim of present study is to identify the breast cancer screening barriers among the women with breast cancer of Malwa region of Punjab,India.The study was conducted at three government hospitals representing almost all districts of Malwa region.Methods:The quantitative research design was followed using empirical research methods.Study was carried out by one-to-one interview by the field investigator and research assistant.Total of 363 breast cancer patient has been interviewed through the scheduled questionnaire and results has been recorded for further analysis.In this study,five barriers are described namely as personal barriers,socio-cultural barriers,economic barriers,health­system barriers,and treatment barriers which contains various questions regarding barriers to breast cancer screening.Univariate analysis methods have been used for the analysis to access the socio-demographic profile of women.Data has been obtained with the help of 5-point liker scale.Binary logistic model was chosen.Results:Majority of participants were in the age groups 50-<60 years(3&6%,140/363)and>60 years(31.1%,112/363).Majority of these women(47.4%,171/363)were illiterate and most of them were housewives.The major barriers to breast cancer screening faced by most of the women were having no knowledge about screening services(90.9%,329/363),the importance of early diagnosis(90.9%,329/363),different screening methods(95.5%,347/363)and place of availing screening services(91.2%,330/363)misguided belief in God and fate(81.5%,295/363)and preferring duties than taking care of health(70.2%,254/363).Education qualification(odds ratio[OR]0.74,β'=-0.309,t=-5.357,P=0.000)and socioeconomic class(OR 1.43,β’=0.354,t=3.399,P=0.001)were found to be significant determinant of the barriers among women.Conclusion:The survey was conducted in the women between the age 40-60 years and as an outcome,the unawareness about screening services,fatalistic attitude,fear of being diagnosed with the cancer,low per capita income was found out significant factors that restricted the women for early check-up for the breast cancer.

Factors that contribute to delay in seeking cervical cancer diagnosis and treatment among women in Malawi

Cervical cancer is a curable disease if diagnosed early. However, many women in Malawi seek treatment when the disease has reached inoperable stage. This study was conducted to explore factors that contribute to delay in seeking early diagnosis and treatment of cervical cancer among women in Malawi. The study was exploratory and utilized qualitative data collection and analysis method. In-depth interviews were conducted using a semi-structured interview guide on a purposive sample of 24 women who were diagnosed of cervical cancer at the gynaecological wards of Zomba and Queen Elizabeth Central Hospitals in Malawi between July and September, 2011. Thematic content analysis was used to analyze the qualitative data. Two major themes (individual and health facility) emerged from the participants’ narratives as factors that contributed to their delay in seeking early diagnosis and treatment. The individual factors included;limited knowledge on symptoms and signs and limited financial resources. The health facilities factors included;limited accessibility and unavailability of cancer screening facilities in the health centres. Results show that there is a need to strengthen the screening of cervical cancer among women in the country. In addition, there is a need to create community awareness on the signs and symptoms of cervical cancer and the merits of seeking early diagnosis and treatment.

Analysis of nutritional risk,skeletal muscle depletion,and lipid metabolism phenotype in acute radiation enteritis

BACKGROUND Radiation enteritis,which often occurs during radiation-induced acute intestinal symptoms(RIAIS),is the most common and important complication during radiotherapy for cervical cancer.RIAIS caused by abdominal and pelvic radiotherapy will affect nutrient intake,digestion,absorption,and metabolism,leading to malnutrition or poorer nutritional status.In patients with malignant tumors,malnutrition can adversely affect the curative effect and response of radiotherapy by reducing radiosensitivity,affecting the precision of radiotherapy placement and increasing the incidence of radiotherapy-related adverse reactions.AIM To analyze nutritional risk,skeletal muscle depletion,and lipid metabolism phenotype in acute radiation enteritis.METHODS Fifty patients with cervical cancer received external beam radiotherapy,and 15 patients received brachytherapy after external beam radiotherapy.Body weight,body composition parameters,nutritional risk screening(NRS)2002 score,and blood biochemical indices of patients with cervical cancer during periradiation were tested by a one-way repeated measures analysis of variance.Metabolomics analysis was used to identify characteristic lipid metabolism pathways.Clinical factors that affect linoleic acid changes were screened using the generalized evaluation equation.RESULTS Among the 50 patients,37 had RIAIS,including 34 patients with grade 1-2 RIAIS and 3 patients with grade 3 RIAIS.The NRS 2002 score of patients who underwent cervical cancer radiotherapy continued to increase during the periradiation period,and 42 patients who underwent cancer radiotherapy had nutritional deficits(NRS 2002 score≥3 points)at the end of radiotherapy.Correlation analyses revealed that body weight and body mass index changes were closely associated with body fat content(R2=0.64/0.51).The results of the univariate analysis showed that radiotherapy time,percentage reduction of serum albumin,and percentage reduction of serum prealbumin were the key factors affecting skeletal muscle exhaustion(P<0.05).Metabolomic analysis of fecal supernatants of cervical cancer patients during the periradiation period revealed the involvement of linoleic acid,cholic acid,arachidonic acid,and N-acetyl-L-benzene alanine in the metabolic pathway of linoleic acid.CONCLUSION Cervical cancer radiotherapy patients faced nutritional risks,decreased serum albumin synthesis,and increased risk of skeletal muscle exhaustion.Linoleic acid was a biomarker of high nutritional risk.

ACUPUNCTURE TREATMENT OF CERVICAL SPONDYLOPATHY:CLINICAL REPORT OF 172 CASES

The authors have treated 172 cases of cervical spondylopathy with acupuncture basedon the differentiation of symptoms and signs.Of 172 cases,58（33.2％）were cured,60（35.0％）were markedly improved,and 48（27.9％）were improved.The total effective rate was 96.1％.Acupuncture treatment is more effective for cervical spondylopathy with little change in bone sub-stance,but less effective in cases with severe bone proliferation.And its eminant effect is an algesia,no significant change is found in X-ray examination before and after treatment.

妇科恶性肿瘤患者围术期症状群和核心症状的研究

目的探讨妇科恶性肿瘤患者在围术期不同时间点症状群的构成及动态变化,构建症状网络,探索核心症状,为制定精准的症状管理方案提供参考。方法便利抽样法选取260例妇科恶性肿瘤(宫颈癌、卵巢癌、子宫内膜癌)手术患者进行调查,采用一般资料调查问卷和中文版安德森症状系列量表-妇科恶性肿瘤围手术期模块分别于手术前1 d(T1)、术后第3天(T2)和术后第7天(T3,即出院前)3个时间点对患者进行纵向调查。对3个时间点中发生率>20%的症状行探索性因子分析提取症状群,运用R语言构建症状网络,分析中心性指标。结果妇科恶性肿瘤患者围术期共提取4个症状群,分别是疲乏-疼痛-情绪症状群、消化道症状群、能量不足症状群和潮热-神经症状群。其中疲乏-疼痛-情绪症状群持续存在于T1~T3,且群内症状组成较稳定。潮热-神经症状群存在于T1~T3、消化道症状群存在于T2和T3、能量不足症状群仅存在于T2,且群内症状组成呈动态变化。症状网络中,悲伤和苦恼是围术期3个时间点的核心症状,其他中心性指标动态变化。T1除悲伤外,潮热的紧密中心性和中介中心性最大,T2恶心、T3疲乏的紧密中心性和中介中心性最大。结论医护人员应对稳定存在的症状群及核心症状进行全程干预,将症状群与网络中心性指标相结合,制定更为精准的管理方案,改善患者围术期生活质量。

症状管理理论下的姑息护理对宫颈癌晚期患者的应用价值

目的 探究症状管理理论下的姑息护理对宫颈癌晚期患者的应用价值。方法 选取2019年7月至2022年7月南通市第三人民医院抽取的100例宫颈癌晚期患者作为研究对象,按照随机数字表法将其分成对照组和观察组,每组50例。对照组采用常规的姑息护理,观察组在对照组基础上增加症状管理理论下的姑息护理,两组均护理1个月。比较两组干预前后中文版压力知觉量表(CPSS)、癌因性疲乏(CRF)量表,及世界卫生组织生活质量测定量表(WHOQOL-BREF)。结果 干预后,两组CPSS、CRF评分低于干预前,且观察组低于对照组(P<0.05)。干预后,两组WHOQOL-BREF评分均高于干预前,且观察组高于对照组(P<0.05)。结论 针对宫颈癌晚期患者采取症状管理理论下的姑息护理,可在降低患者心理弹性表现的同时,还能够改善患者的CRF量表评分,进而提高患者的患病后生活质量,值得各个科室借鉴采纳。

Helicobacter pylori-induced inflammation masks the underlying presence of low-grade dysplasia on gastric lesions

BACKGROUND Helicobacter pylori(H.pylori)infection has been associated with a long-term risk of precancerous gastric conditions(PGC)even after H.pylori eradication.AIM To investigate the efficacy of High-Resolution White-Light Endoscopy with Narrow-Band Imaging in detecting PGC,before/after H.pylori eradication.METHODS We studied 85 consecutive patients with H.pylori-related gastritis with/without PGC before and 6 mo after proven H.pylori eradication.Kimura-Takemoto modified and endoscopic grading of gastric intestinal metaplasia classifications,were applied to assess the endoscopic extension of atrophy and intestinal metaplasia.The histological result was considered to be the gold standard.The Sydney System,the Operative-Link on Gastritis-Assessment,and the Operative-Link on Gastric-Intestinal Metaplasia were used for defining histological gastritis,atrophy and intestinal metaplasia,whereas dysplasia was graded according to World Health Organization classification.Serum anti-parietal cell antibody and anti-intrinsic factor were measured when autoimmune atrophic gastritis was suspected.RESULTS After H.pylori eradication histological signs of mononuclear/polymorphonuclear cell infiltration and Mucosal Associated Lymphoid Tissue-hyperplasia,disappeared or decreased in 100%and 96.5%of patients respectively,whereas the Operative-Link on Gastritis-Assessment and Operative-Link on Gastric-Intestinal Metaplasia stages did not change.Low-Grade Dysplasia prevalence was similar on random biopsies before and after H.pylori eradication(17.6%vs 10.6%,P=0.19),but increased in patients with visible lesions(0%vs 22.4%,P<0.0001).At a multivariate analysis,the probability for detecting dysplasia after resolution of H.pylori-related active inflammation was higher in patients with regression or reduction of Mucosal Associated Lymphoid Tissue hyperplasia,greater alcohol consumption,and anti-parietal cell antibody and/or anti-intrinsic factor positivity[odds ratio(OR)=3.88,95%confidence interval(CI):1.31-11.49,P=0.01;OR=3.10,95%CI:1.05-9.12,P=0.04 and OR=5.47,95%CI:1.33-22.39,P<0.04,respectively].CONCLUSION High-Resolution White-Light Endoscopy with Narrow-Band Imaging allows an accurate diagnosis of Low-Grade Dysplasia on visible lesions after regression of H.pylori-induced chronic gastritis.Patients with an overlap between autoimmune/H.pylori-induced gastritis may require more extensive gastric mapping.

Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy

Objective:To compare the degree of agreement and consistency of urodynamic studies(UDS)with low urinary tract symptoms(LUTS)questionnaires for evaluating LUTS in cervical cancer patients following radical hysterectomy(RH)and pelvic lymphadenectomy.Methods:From January 2012 to March 2015,204 cervical cancer patients who underwent RH in 13 hospitals were evaluated using the Incontinence Questionnaire-Female Lower Urinary Tract Symptoms(ICIQ-FLUTS)and the Overactive Bladder Symptom Score(OABSS).Urodynamic tests were also performed on these patients during the same period.Results:Study participants’age ranged from 23 to 75 years,with a mean(standard deviation)of 48.0±9.3 years.Using questionnaires,the prevalence of patients with LUTS symptoms,including storage symptoms,voiding symptoms,stress urinary incontinence(SUI)and overactive bladder(OAB)was 86.3%,77.0%,62.7%,52.9%and 14.7%,respectively.For UDS,the corresponding prevalence was 89.7%,70.1%,66.7%,46.6%and 13.2%,respectively.The diagnostic concordance of questionnaires and UDS for storage symptoms,voiding symptoms,SUI and OAB was 79.9%,66.7%,66.7%,57.4%and 79.9%,respectively.For voiding symptoms,the correlation coefficient was 0.272,which was higher than that of storage symptoms,SUI and OAB.

卵巢癌化疗患者消化道症状群管理的最佳证据总结

目的检索、评价并整合卵巢癌化疗患者消化道症状群管理的最佳证据。方法根据“6S”模型,系统检索相关中英文数据库和网站中有关卵巢癌化疗患者消化道症状群管理的文献,包括临床决策、指南、专家共识、证据总结及系统评价,检索时限为2013年1月-2023年3月。结果共纳入18篇文献,其中临床决策2篇、指南5篇、专家共识4篇、证据总结2篇、系统评价5篇。从恶心与呕吐、腹泻、口腔黏膜炎、食欲下降和味觉改变的管理及多学科团队5个方面总结出28条证据。结论该研究总结的卵巢癌化疗患者消化道症状群管理的最佳证据,可为临床实践提供循证依据,医护人员可在此基础上根据患者的实际症状和需求,制订个性化的护理管理方案。

探讨直肠癌术前辅助放化疗引起放射性直肠炎的标准化分级护理

目的:分析标准化分级护理模式在直肠癌术前辅助放化疗引起放射性直肠炎患者护理干预中的应用效果。方法:选择蚌埠医学院第一附属医院于2021年3月至2021年12月收治的52例直肠癌术前辅助放化疗引起放射性直肠炎患者,采取常规护理干预;同时选择2022年1月至2022年10月收治的52例,采取标准化分级护理干预,比较护理结果差异。结果:在实施标准化分级护理后,患者干预总有效率显著高于实施前(P<0.05);实施后患者临床症状消失时间明显早于实施前(P<0.05)。结论:在直肠癌术前辅助放化疗引起放射性直肠炎患者临床干预中,标准化分级护理模式解决了传统护理模式下存在的过度护理等问题,有助于提升患者满意度并促进患者临床症状改善,具有显著优势。并且本文的结果也证实,标准化分级护理模式可以加快患者临床症状改善,有更满意的干预效果,具有推广价值。

正念减压疗法护理对宫颈癌放化疗患者负性情绪及症状群的影响

目的探讨在宫颈癌放化疗患者中实施正念减压护理对患者焦虑、抑郁及症状群的影响。方法选取2021年7—12月宫颈癌放化疗患者60例,按床号的单双数依次分为对照组和观察组,每组30例。对照组给予常规心理护理,观察组给予正念减压疗法护理干预。干预6周后,比较两组患者焦虑、抑郁及症状群评分情况。结果干预后观察组患者焦虑、抑郁得分均低于对照组,差异有统计学意义(P<0.05)。干预后观察组患者悲伤感、苦恼、食欲下降、疲乏、睡眠不安、嗜睡方面得分低于对照组,差异有统计学意义(P<0.05);而恶心、呕吐、疼痛、健忘、口干、气促、麻木感方面得分差异无统计学意义(P>0.05)。结论正念减压疗法能有效减轻宫颈癌放化疗患者焦虑、抑郁等负性情绪,缓解患者悲伤感、苦恼、疲乏、睡眠不安、嗜睡等症状群,帮助患者以更好的身心状态面对疾病,积极配合疾病诊治。

宽筋藤合剂联合壮医经筋疗法治疗交感神经型颈椎病患者的疗效观察

目的 观察应用宽筋藤合剂联合壮医经筋疗法治疗交感神经型颈椎病患者的临床疗效。方法 选取2021年6月—2022年7月期间在广西国际壮医院针灸推拿科治疗的240例交感神经型颈椎病患者,按照随机数字表法分为观察组和对照组,每组各120例。对照组采用常规推拿针刺手法,观察组采用壮医经筋疗法联合宽筋藤合剂。治疗2周后,观察比较两组患者临床疗效、不良反应情况,治疗前后对患者颈椎疼痛评分(Visual analogue scale, VAS)、交感神经症状评分、椎动脉与基底动脉平均血流速度[右椎动脉(Right vertebral artery, RVA)、左椎动脉(Left vertebral artery, LVA)、基底动脉(Basilar artery, BA)]、血液流变学指标[全血高、中、低切黏度(Whole blood viscosity with high, midst and low, WBV),血浆黏度(Plasma viscosity, ηb),红细胞压积(Hematocrit, HCT)、血沉(Erythrocyte sedimentation rate, ESR)、红细胞聚集指数(Red blood cell aggregation index, AI)]变化。结果 治疗后观察组临床总有效率92.86%(104/112)明显高于对照组82.69%(86/104),差异有统计学意义(P<0.05)。治疗2周后对照组VAS、交感神经症状评分均较治疗前降低,差异有统计学意义(P<0.05);治疗1、2周后观察组VAS、交感神经症状评分均较治疗前明显降低,差异有统计学意义(P<0.05);且观察组VAS、交感神经症状评分均优于对照组治疗同期,差异有统计学意义(P<0.05)。治疗2周后观察组患者LVA、RVA与BA平均血流速度均较治疗前明显加快,差异有统计学意义(P<0.05);且观察组LVA、RVA与BA平均血流速度均优于对照组,差异有统计学意义(P<0.05)。治疗2周后观察组患者WBV、ηb、HCT、ESR及AI指标均较治疗前明显降低,差异有统计学意义(P<0.05);且观察组WBV、ηb、HCT、ESR及AI指标均较对照组明显降低,差异有统计学意义(P<0.05)。治疗期间,两组患者均无不良反应发生。结论 应用壮医经筋疗法联合宽筋藤合剂治疗交感神经型颈椎病,能够明显改善患者脑部供血、颈椎生理曲度,提高治疗交感神经型颈椎病临床总有效率。

宫颈癌化疗患者生活质量与周围神经病变和心理弹性及症状严重程度的相关性分析

目的:探讨宫颈癌化疗患者生活质量与周围神经病变、心理弹性及症状严重程度的相关性。方法:选取2018年9月—2020年9月收治的宫颈癌患者109例,对其不同文化程度、年龄、婚姻情况和生育情况等人口学资料及生活质量评分进行比较,并对其周围神经病变、心理弹性及症状群情况进行评估,采用多元线性回归分析其生活质量和周围神经病变、心理弹性及症状严重程度间的相关性,并提出干预建议。结果:不同文化程度、年龄、婚姻情况和生育情况等人口学资料对生活质量评分无明显影响(P>0.05)。多元线性回归分析结果显示,周围神经病变、悲伤、疲乏、食欲缺乏、睡眠不安、呕吐与生活质量呈负相关(P<0.05),心理弹性与生活质量呈正相关(P<0.05)。结论:宫颈癌患者化疗后周围神经病变、症状严重程度、心理弹性与生活质量密切相关,临床需采取相应干预措施,降低患者周围神经病变严重程度,提高患者心理弹性水平,进而改善患者的生活质量。

基于文献数据挖掘的前列腺癌中医证候规律研究

目的:通过文献数据挖掘探讨前列腺癌中医证素及症状/体征分布规律,为辨证论治提供参考。方法:检索中国知网、万方、维普及中国生物医学文献数据库中前列腺癌中医证型、证素及症状/体征相关文献,建立数据库,运用SPSS Statistics 26.0和Gephi 0.9.2软件进行因子、聚类及复杂网络分析,挖掘前列腺癌患者的中医证候特点和分布规律。结果:前列腺癌证型分布以下焦湿热证多见,总体以虚证为主。证素分布显示病位多在肾、脾、肝及下焦,病理性质正虚邪实,正虚以气、阴、阳、血的亏虚为主,实以血瘀、湿、热、毒、痰为主。证素聚类分析结果分为7类:肾阳亏虚证、毒瘀互结证、脾气血两虚证、肝阴亏虚证、下焦湿热证、痰浊内阻证和气机郁滞证。症状/体征复杂网络分析核心症状/体征为尿频尿急、小便不利、神疲乏力、纳呆、腰膝酸软、腰痛、失眠、夜尿多、舌红、腹部胀痛、大便干燥、口干口渴、排尿疼痛、消瘦、畏寒肢冷。症状/体征因子及聚类分析最终聚为5类:气阴亏虚证、肾阳亏虚证、肾虚湿热证、气虚血瘀证、热毒内蕴证。结论:正虚邪实是前列腺癌变化发展的主要病机,肾阳亏虚证、气阴亏虚证、下焦湿热证、毒瘀互结证是前列腺癌的临床常见证型。

陆氏针灸治疗椎动脉型颈椎病的效果研究

目的:观察比较陆氏针灸与口服西药治疗椎动脉型颈椎病的临床疗效差异。方法:将92例患者随机分为陆氏针灸组及敏使朗组各46例,陆氏针灸组取风池、新设、大椎、百会、列缺用陆氏针灸治疗,敏使朗组口服敏使朗治疗。比较两组的临床疗效、治疗前后的症状与体征、NPQ量表评分、SF-MPQ量表评分和TCD指标。结果:陆氏针灸组总有效率100%,高于敏使朗组的80.43%,差异具有统计学意义(P<0.01)。两组治疗后症状体征评分、NPQ量表评分、SF-MPQ量表评分均较同组治疗前明显降低(均P<0.01),治疗后两组椎-基底动脉的收缩峰值、舒张末期及平均血流速度均较治疗前明显升高(均P<0.01);且陆氏针灸组症状体征评分、NPQ量表评分、现有疼痛强度PPI评分的差值优于敏使朗组(P<0.05、P<0.01、P<0.01),对基底动脉的收缩峰值、舒张末期和平均血流速度、左侧椎动脉的舒张末期血流速度的改善均优于敏使朗组(P<0.01、P<0.05、P<0.05、P<0.05)。结论:陆氏针灸治疗椎动脉型颈椎病的疗效显著,可改善患者的临床症状,降低颈痛程度,增加椎-基底动脉血流速度,改善大脑供血。

针灸联合整脊疗法治疗神经根型颈椎病的临床观察

目的:观察针灸联合整脊疗法治疗神经根型颈椎病的临床效果。方法:择取2022年1月至2023年1月广州市天河区中医医院康复科收治的80例神经根型颈椎病病例,随机分为Α组和Β组,每组40例。Β组实施单纯针灸治疗,Α组实施针灸联合整脊治疗,对比两组的临床疗效、治疗后症状及体征积分、不良反应。结果:(1)总有效率:Α组的治疗总有效率(92.5%)高于Β组(75.0%),差异有统计学意义(P<0.05)。(2)症状及体征积分:治疗后,Α组的疼痛、麻木、棘突旁压痛、臂丛牵拉试验、压顶试验、上肢功能、上肢肌力、腱反射积分均低于Β组,差异有统计学意义(P<0.05)。(3)不良反应:两组不良反应的发生率无显著差异(P>0.05)。结论:针灸联合整脊疗法治疗神经根型颈椎病的临床效果确切,可有效改善患者的症状及体征,且安全性良好。

宫颈癌病人症状群的研究进展

综述宫颈癌症状群的概念、研究现状、宫颈癌病人症状群的评估工具,探讨宫颈癌病人症状群研究的最新进展,为临床上实施个体化症状管理方案提供参考。

轻中度颈脊髓压迫患者产生脊髓损害症状与体征的危险因素

目的：探讨轻中度颈脊髓压迫患者产生脊髓损害症状与体征的危险因素。方法：回顾性分析我院脊柱外科2008年11月．2011年11月门诊诊治的68例轻、中度颈脊髓压迫患者的病例资料。男37例，女31例。单节段32例，两节段22例，三节段14例。患者均有颈椎正侧位和过伸过屈位X线平片和颈椎CT及MRI检查图片。根据有无脊髓损害症状与体征，将其分为两组，无脊髓损害症状与体征的30例患者为A组，有脊髓损害症状与体征的38例患者为B组，比较两组患者年龄、性别、病程、病变节段数日，以及最大受压节段颈椎管比率、整体活动范同、节段不稳发生率、C2～C7Cobb角、脊髓受压方向及脊髓高信号发生率。结果：两组患者年龄、性别、病程、病变节段数目差异均无统计学意义；平均最大受压节段颈椎管比率，A组为90.3％，B组为83．6％（P〈0．05）；平均颈椎整体活动范围A组为47．5°，B组为44．1°（P〉0．05）；颈椎节段不稳发生率，A组为23．3％，B组为65．8％（P〈0．05）；平均C2～C7Cobb角A组为14．1°，B组为14．1°（P〉0．05）；脊髓受压方向，A组中央掣19例，旁中央型11例，B组中央型17例，旁中央型21例（P〉0．05）；颈椎MRIT2加权像高信号发牛率。A组为13．3％，B组为86．9％（P〈0．05）。结论：对于轻、中度颈脊髓压迫患者。颈椎节段不稳和脊髓高信号是导致出现脊髓损害症状与体征的危险因素，而颈椎管比率较大是一种保护因素，尚不能认为脊髓受压力’向、颈椎整体曲度和活动范围对出现脊髓损害症状与体征产生影响。

针刀松解对神经根型颈椎病症状体征改变的临床观察

目的:观察针刀松解治疗神经根型颈椎病症状体征的改变,评价针刀松解对神经根型颈椎病的有效性。方法:将224例符合神经根型颈椎病诊断的患者,采用随机入组分配至针刀松解治疗组116例,电针治疗对照组108例。采用积分法比较两组治疗后症状总积分,臂丛牵拉试验、椎间孔挤压试验体征积分的变化。结果:两组治疗后症状总积分、臂丛牵拉试验、椎间孔挤压试验单项积分均有显著疗效(P<0.05),且针刀组优于电针组(P<0.05)。结论:针刀松解对神经根型颈椎病的治疗是有效的。