This paper investigates the verb valency structure of English that is used by English as Foreign Language(EFL)learners from a corpus-driven perspective.Specifically,it focuses on the usage of the verbs“suggest”and“...This paper investigates the verb valency structure of English that is used by English as Foreign Language(EFL)learners from a corpus-driven perspective.Specifically,it focuses on the usage of the verbs“suggest”and“advise”in a selected corpus.By analyzing a sample of written and spoken texts,this study attempts to investigate the similarities and differences in the patterns of verb valency between native English speakers and Chinese EFL learners.The findings of this research can contribute to a better understanding of the challenges faced by Chinese EFL learners in acquiring accurate verb valency structures and provide insights for language teachers in designing effective pedagogical approaches.展开更多
The discrimination of synonyms has always been one of the great challenges for English learners.Taking assessment and evaluation as examples,this study analyses the similarities and differences of the two words,as wel...The discrimination of synonyms has always been one of the great challenges for English learners.Taking assessment and evaluation as examples,this study analyses the similarities and differences of the two words,as well as their usage from the perspectives of frequency,stylistics,collocation and semantic prosody with the help of British National Corpus,and demonstrates the importance of corpus retrieval tools in synonyms discrimination.Furthermore,this paper will give some suggestions for English learners and teachers in English vocabulary teaching.展开更多
Aim: This study aimed to investigate the effect of non-synonymous SNPs (nsSNPs) of the Glucagon-like peptide-1 Receptor (GLP-1R) gene in protein function and structure using different computational software. Introduct...Aim: This study aimed to investigate the effect of non-synonymous SNPs (nsSNPs) of the Glucagon-like peptide-1 Receptor (GLP-1R) gene in protein function and structure using different computational software. Introduction: The GLP1R gene provides the necessary instruction for the synthesis of the insulin hormones which is needed for glucose catabolism. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type-2 diabetes and stroke. Material and Methods: Different nsSNPs and protein-related sequences were obtained from NCBI and ExPASY database. Gene associations and interactions were predicted using GeneMANIA software. Deleterious and damaging effects of nsSNPs were analyzed using SIFT, Provean, and Polyphen-2. The association of the nsSNPs with the disease was predicted using SNPs & GO software. Protein stability was investigated using I-Mutant and MUpro software. The structural and functional impact of point mutations was predicted using Project Hope software. Project Hope analyzes the mutations according to their size, charge, hydrophobicity, and conservancy. Results: The GLP1R gene was found to have an association with 20 other different genes. Among the most important ones is the GCG (glucagon) gene which is also a trans membrane protein. Overall 7229 variants were seen, and the missense variants or nsSNPs (146) were selected for further analysis. The total number of nsSNPs obtained in this study was 146. After being subjected to SIFT software (27 Deleterious and 119 Tolerated) were predicted. Analysis with Provean showed that (20 deleterious and 7 neutral). Analysis using Polyphen-2 revealed 17 probably damaging, 2 possibly damaging and 1 benign nsSNPs. Using two additional software SNPs & GO and PHD-SNPs showed that 14 and 17 nsSNPs had a disease effect, respectively. Project Hope software predicts the effect of the 14 nsSNPs on the protein function due to differences in charge, size, hydrophobicity, and conservancy between the wild and mutant types. Conclusion: In this study, the 14 nsSNPs which were highly affected the protein function. This protein is providing the necessary instruction for the synthesis of the insulin hormones which is needed for glucose catabolism. Polymorphisms in this gene are associated with diabetes and also affect the treatment of diabetic patients due to the fact that the protein acts as an important drug target.展开更多
The genus Fuscoptilia is reviewed in this paper. Fuscoptilia hoenei Arenberger, a new synonym of Fuscoptilia sinuata (Qin & Zheng), is established. The females of Fuscoptilia sinuata (Qin & Z...The genus Fuscoptilia is reviewed in this paper. Fuscoptilia hoenei Arenberger, a new synonym of Fuscoptilia sinuata (Qin & Zheng), is established. The females of Fuscoptilia sinuata (Qin & Zheng) and Fuscoptilia jarosi Arenberger are described for the first time in science. The adults are photographed, and the male and female genital structures are figured. A key to the described species in the world is given.展开更多
The identity of two Lyristes species described by Schmidt is readdressed based on examination of the type materials. Lyristes wui Schmidt, 1932 is recognized to be a junior synonym of Salvazana mirabilis Distant, 1913...The identity of two Lyristes species described by Schmidt is readdressed based on examination of the type materials. Lyristes wui Schmidt, 1932 is recognized to be a junior synonym of Salvazana mirabilis Distant, 1913, and Lyristes altaiensis Schmidt, 1932 is a junior synonym of a North American species, Neotibicen resh (Haldeman, 1852). Lyristes altaiensis may have been erroneously recorded from China most possibly due to the mislabeling of the holotype.展开更多
The genus Oralia Malaise is recorded from China with three species described as new to science: Oralia fulva sp. nov., Oralia acuritheca sp. nov., Oralia tibetana sp. nov.. The genus Himindica Sain...The genus Oralia Malaise is recorded from China with three species described as new to science: Oralia fulva sp. nov., Oralia acuritheca sp. nov., Oralia tibetana sp. nov.. The genus Himindica Saini, 1996 is treated as junior synonym of Oralia Malaise, 1961. Two new specific synonyms and two new combinations are proposed: Oralia nigroclypeata Malaise, 1961 = Himindica nigrothorax Saini et Vasu, 1997, syn. nov., Oralia fossulata Malaise, 1961 = Himindica maculipleuris Saini et Vasu, 1997, syn. nov.; Oralia himalayaensis (Saini et Deep, 1991), comb. nov., Oralia meghalayaensis (Saini et Vasu, 1997), comb. nov. A synoptic key is also provided for the known species of Oralia Malaise.展开更多
Based on comparison of the type specimens, Parapolytrechus [sic] flavotarsus Wang & Zheng, 2002 is a new junior synonym ofNeoxenicotela mausoni Breuning, 1947.
All Chinese species of the genus Milesia is revised in this paper. Six new synonyms were proposed, which are M. ruiliana Yang et Cheng and M. Tachina Yang et Cheng as synonyms of M. cretosa Hippa; M. maolana Cheng et ...All Chinese species of the genus Milesia is revised in this paper. Six new synonyms were proposed, which are M. ruiliana Yang et Cheng and M. Tachina Yang et Cheng as synonyms of M. cretosa Hippa; M. maolana Cheng et Yang as synonym of M. ferruginosa Brunetti; M. atricorporis Yang et Cheng as synomym of M. quantula Hippa; M. vesparia Shiraki and M. turgidiverticis Yang et Cheng as synonyms of M. verticalis Brunetti. As far as we know, there are thirteen species distributing in China, among which, M. variegata Brunetti is recorded for the first time to China. An abdominal figure of each species is provided in this paper. Meanwhile, a key to all the Chinese species and a map of geographical distribution of these species are given.展开更多
As a medium between two different languages, between peoples of two countries, translation is not only a matter of language, but also of cross-cultural transference. According to Professor He Ziran, socio-pragmatic tr...As a medium between two different languages, between peoples of two countries, translation is not only a matter of language, but also of cross-cultural transference. According to Professor He Ziran, socio-pragmatic translation is the kind of translation which examines the conditions on language use that stem from the social and cultural situations to serve cross-cultural communication. This paper focuses on the ways used to achieve socio-pragmatic equivalence in translation practice.展开更多
Key Facts Synonyms:Sacrococcygeal teratoma(SGT),germ cell tumor of coccyx Definition:Tumors containing hair,teeth,cartilage,and fat extending from the coccyx and potentially growing both internally and externally.
Nowadays,more and more university students have Teacher’s Book for College English. They know answers of exercises from it before they do them. Some of them just copy down the right answers and wait for teacher’s pr...Nowadays,more and more university students have Teacher’s Book for College English. They know answers of exercises from it before they do them. Some of them just copy down the right answers and wait for teacher’s praise. In this situation, College English teachers should redesign the exercises after each unit so that students will be interested and involved in learning. This study thus suggests several ways to redesign the vocabulary exercises from “ College English". It expects, on the one hand, to raise College English teachers’ awareness of the necessity to change the exercises. On the other hand, it expects to give them an inspiration, and example of designing more appropriate exercises so as to reinforce students’ vocabulary and enhance their language awareness.展开更多
Synonyms: Epidermoid tumor,non-neoplastic inclusion cyst, congenital cholesteatoma of the cerebellopontine angle cistern.Definition: Congenital lesion arising from inclusion of ectodermal epithelial elements at time o...Synonyms: Epidermoid tumor,non-neoplastic inclusion cyst, congenital cholesteatoma of the cerebellopontine angle cistern.Definition: Congenital lesion arising from inclusion of ectodermal epithelial elements at time of neural tube closure during 3rd to 5th week of embryonic life, resulting in migration abnormalities of epiblastic cells.Classic imaging appearance:(1)Signal shows an insinuating cisternal lesion with low T1, high T2 close to that of cerebrospinal fluid (CSF).(2)FLAIR shows incomplete or absent attenuation.(3)Diffusion-weighted imaging shows epidermoid cyst has restricted diffusion(high-signal lesion).Other key facts:(1)3rd most common cerebellopontine angle-internal auditory canal (CPA-IAC) mass.(2)1% of all intracranial tumors.展开更多
In this study, a comparative analysis of the codon usage bias was performed in Aeropyrum pernix K1 and two other phylogenetically related Crenarchaeota microorganisms (i.e., Pyrobaculum aerophilum str. IM2 and Sulfol...In this study, a comparative analysis of the codon usage bias was performed in Aeropyrum pernix K1 and two other phylogenetically related Crenarchaeota microorganisms (i.e., Pyrobaculum aerophilum str. IM2 and Sulfolobus acidocaldarius DSM 639). The results indicated that the synonymous codon usage in A. pernix K1 was less biased, which was highly correlated with the GC3s value. The codon usage patterns were phylogenetically conserved among these Crenarchaeota microorganisms. Comparatively, it is the species function rather than the gene function that determines their gene codon usage patterns. A. pernix K1, P. aerophilum str. IM2, and S. acidocaldarius DSM 639 live in differently extreme conditions. It is presumed that the hving environment played an important role in determining the codon usage pattern of these microorganisms. Besides, there was no strain-specific codon usage among these microorganisms. The extent of codon bias in A. pernix K1 and S. acidocaldarius DSM 639 were highly correlated with the gene expression level, but no such association was detected in P. aerophilum str. IM2 genomes.展开更多
The genus Boeberia Prout,1901 from China is reviewed. A previously known species is redescribed: Boeberia parmenio(Bber,1809) and one species is synonymized: Boeberia polyommata Chou and Yuan,2001(=Satyrus ferula...The genus Boeberia Prout,1901 from China is reviewed. A previously known species is redescribed: Boeberia parmenio(Bber,1809) and one species is synonymized: Boeberia polyommata Chou and Yuan,2001(=Satyrus ferula(Fabricius,1793)) . Illustrations of adults and male genitalia are provided.展开更多
Apple(Malus×domestica) has been proposed as an important woody plant and the major cultivated fruit trees in temperate regions. Apple whole genome sequencing has been completed, which provided an excellent oppo...Apple(Malus×domestica) has been proposed as an important woody plant and the major cultivated fruit trees in temperate regions. Apple whole genome sequencing has been completed, which provided an excellent opportunity for genome-wide analysis of the synonymous codon usage patterns. In this study, a multivariate bioinformatics analysis was performed to reveal the characteristics of synonymous codon usage and the main factors affecting codon bias in apple. The neutrality, correspondence, and correlation analyses were performed by Codon W and SPSS(Statistical Product and Service Solutions) programs, indicating that the apple genome codon usage patterns were affected by mutational pressure and selective constraint. Meanwhile, coding sequence length and the hydrophobicity of proteins could also influence the codon usage patterns. In short, codon usage pattern analysis and determination of optimal codons has laid an important theoretical basis for genetic engineering, gene prediction and molecular evolution studies in apple.展开更多
There is strong relationship between melanocortin-1 receptor (MCIR) gene variants and human hair color and skin type. Based on a sequencing study of MC1R gene in 50 individuals from the Uygur, Tibetan, Wa and Dai ethn...There is strong relationship between melanocortin-1 receptor (MCIR) gene variants and human hair color and skin type. Based on a sequencing study of MC1R gene in 50 individuals from the Uygur, Tibetan, Wa and Dai ethnic populations, we discuss the occurrence of 7 mc1r variants consisting of 5 nonsynonymous sites (Val60Leu, Arg67Gln, Val92Met, Arg163Gln and Ala299Val) and 2 synonymous sites (C414T and A942G), among which C414T and Ala299Val were reported for the first time. Confirmation and analysis were the made of 122 individuals at three common point mutations (Val92Met, Arg163Gln, A942G) using PCR-SSCP. The frequency of Arg163Gln variant varies in the four ethnic populations, with percentage of 40%, 85.0%, 66. 2% and 72.7%, respectively, while those of Val92Met and A942G are roughly similar in these four populations. The different environments, migration and admixture of various ethnic groups in China might have impact on the observed frequency of Arg163Gln.展开更多
A comparative analysis of the codon usage bias was conducted in Methanosarcina mazei str. Goel and two related Euryarchaeota microorganisms (Picrophilus torridus str. DSM 9790 and Natronomonas pharaonis str. DSM 2160...A comparative analysis of the codon usage bias was conducted in Methanosarcina mazei str. Goel and two related Euryarchaeota microorganisms (Picrophilus torridus str. DSM 9790 and Natronomonas pharaonis str. DSM 2160). Results revealed that synonymous codon usage in Methanosarcina mazei str. Goel was less biased, which was highly correlated with the GC3S value. And the codon usage patterns were phylogenetically conserved among those Euryarchaeota microorganisms. By employing a hierarchical clustering analysis, it can be seen that it is more the species than the gene function that determines their gene codon usage pattems. Considering that those microorganisms live in different environments where the pH conditions vary quite a lot, it can be presumed that their living environments, especially the pH conditions, play an important role in determining those microorganisms' codon usage pattems.展开更多
For protecting the copyright of a text and recovering its original content harmlessly,this paper proposes a novel reversible natural language watermarking method that combines arithmetic coding and synonym substitutio...For protecting the copyright of a text and recovering its original content harmlessly,this paper proposes a novel reversible natural language watermarking method that combines arithmetic coding and synonym substitution operations.By analyzing relative frequencies of synonymous words,synonyms employed for carrying payload are quantized into an unbalanced and redundant binary sequence.The quantized binary sequence is compressed by adaptive binary arithmetic coding losslessly to provide a spare for accommodating additional data.Then,the compressed data appended with the watermark are embedded into the cover text via synonym substitutions in an invertible manner.On the receiver side,the watermark and compressed data can be extracted by decoding the values of synonyms in the watermarked text,as a result of which the original context can be perfectly recovered by decompressing the extracted compressed data and substituting the replaced synonyms with their original synonyms.Experimental results demonstrate that the proposed method can extract the watermark successfully and achieve a lossless recovery of the original text.Additionally,it achieves a high embedding capacity.展开更多
[Objective] The objective of this study was to understand the codon usage bias pattern of banana pathogenesis-related 17 gene, Basic Secretory Protease gene(MaBSP). [Method] Relative codon usage patterns of MaBSP were...[Objective] The objective of this study was to understand the codon usage bias pattern of banana pathogenesis-related 17 gene, Basic Secretory Protease gene(MaBSP). [Method] Relative codon usage patterns of MaBSP were calculated using the software CodonW version 1.4.2. and the web-based tool(http://kazusa.or.jp/codon/).[Result] Our findings showed that C-ended and G-ended codons were the most preferential except the TER codon UGA which was coded for by just one codon. The ENc value, relationship between AT bias and GC bias, Random synonymous codon usage(RSCU) and CAI all showed that codon bias usage existed in MaBSP gene.[Conclusion] The codon usage patterns of MaBSP gene is principally influenced by natural selection in the third position. However, other multiple factors also influence this pattern.展开更多
With the verification of the type specimen by six experts from the Nanjing Institute of Geology and Palaeontology, the specimen of Xianfengella prima He and Yang, 1982 described by Qian (Qian, 2001, flge2: la-c) is...With the verification of the type specimen by six experts from the Nanjing Institute of Geology and Palaeontology, the specimen of Xianfengella prima He and Yang, 1982 described by Qian (Qian, 2001, flge2: la-c) is confirmed to be the holotype specimen (NIGP. 84430) of Yangtzedonta primitiva Yu, 1985, and consequently, Yu Wen's view that they are not the same specimen is impractical. This fact demonstrates that Yangtzedonta primitiva Yu, 1985 is undoubtedly a junior synonym of Xianftngella prima He and Yang, 1982, and is invalid. Qian's conclusion (Qian, 2001 ) that no bivalve appeared in the early Meishucunian Stage of the Early Cambrian is rational.展开更多
文摘This paper investigates the verb valency structure of English that is used by English as Foreign Language(EFL)learners from a corpus-driven perspective.Specifically,it focuses on the usage of the verbs“suggest”and“advise”in a selected corpus.By analyzing a sample of written and spoken texts,this study attempts to investigate the similarities and differences in the patterns of verb valency between native English speakers and Chinese EFL learners.The findings of this research can contribute to a better understanding of the challenges faced by Chinese EFL learners in acquiring accurate verb valency structures and provide insights for language teachers in designing effective pedagogical approaches.
文摘The discrimination of synonyms has always been one of the great challenges for English learners.Taking assessment and evaluation as examples,this study analyses the similarities and differences of the two words,as well as their usage from the perspectives of frequency,stylistics,collocation and semantic prosody with the help of British National Corpus,and demonstrates the importance of corpus retrieval tools in synonyms discrimination.Furthermore,this paper will give some suggestions for English learners and teachers in English vocabulary teaching.
文摘Aim: This study aimed to investigate the effect of non-synonymous SNPs (nsSNPs) of the Glucagon-like peptide-1 Receptor (GLP-1R) gene in protein function and structure using different computational software. Introduction: The GLP1R gene provides the necessary instruction for the synthesis of the insulin hormones which is needed for glucose catabolism. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type-2 diabetes and stroke. Material and Methods: Different nsSNPs and protein-related sequences were obtained from NCBI and ExPASY database. Gene associations and interactions were predicted using GeneMANIA software. Deleterious and damaging effects of nsSNPs were analyzed using SIFT, Provean, and Polyphen-2. The association of the nsSNPs with the disease was predicted using SNPs & GO software. Protein stability was investigated using I-Mutant and MUpro software. The structural and functional impact of point mutations was predicted using Project Hope software. Project Hope analyzes the mutations according to their size, charge, hydrophobicity, and conservancy. Results: The GLP1R gene was found to have an association with 20 other different genes. Among the most important ones is the GCG (glucagon) gene which is also a trans membrane protein. Overall 7229 variants were seen, and the missense variants or nsSNPs (146) were selected for further analysis. The total number of nsSNPs obtained in this study was 146. After being subjected to SIFT software (27 Deleterious and 119 Tolerated) were predicted. Analysis with Provean showed that (20 deleterious and 7 neutral). Analysis using Polyphen-2 revealed 17 probably damaging, 2 possibly damaging and 1 benign nsSNPs. Using two additional software SNPs & GO and PHD-SNPs showed that 14 and 17 nsSNPs had a disease effect, respectively. Project Hope software predicts the effect of the 14 nsSNPs on the protein function due to differences in charge, size, hydrophobicity, and conservancy between the wild and mutant types. Conclusion: In this study, the 14 nsSNPs which were highly affected the protein function. This protein is providing the necessary instruction for the synthesis of the insulin hormones which is needed for glucose catabolism. Polymorphisms in this gene are associated with diabetes and also affect the treatment of diabetic patients due to the fact that the protein acts as an important drug target.
基金pported by the National Natural Science Foundation of China(30270181)
文摘The genus Fuscoptilia is reviewed in this paper. Fuscoptilia hoenei Arenberger, a new synonym of Fuscoptilia sinuata (Qin & Zheng), is established. The females of Fuscoptilia sinuata (Qin & Zheng) and Fuscoptilia jarosi Arenberger are described for the first time in science. The adults are photographed, and the male and female genital structures are figured. A key to the described species in the world is given.
文摘The identity of two Lyristes species described by Schmidt is readdressed based on examination of the type materials. Lyristes wui Schmidt, 1932 is recognized to be a junior synonym of Salvazana mirabilis Distant, 1913, and Lyristes altaiensis Schmidt, 1932 is a junior synonym of a North American species, Neotibicen resh (Haldeman, 1852). Lyristes altaiensis may have been erroneously recorded from China most possibly due to the mislabeling of the holotype.
文摘The genus Oralia Malaise is recorded from China with three species described as new to science: Oralia fulva sp. nov., Oralia acuritheca sp. nov., Oralia tibetana sp. nov.. The genus Himindica Saini, 1996 is treated as junior synonym of Oralia Malaise, 1961. Two new specific synonyms and two new combinations are proposed: Oralia nigroclypeata Malaise, 1961 = Himindica nigrothorax Saini et Vasu, 1997, syn. nov., Oralia fossulata Malaise, 1961 = Himindica maculipleuris Saini et Vasu, 1997, syn. nov.; Oralia himalayaensis (Saini et Deep, 1991), comb. nov., Oralia meghalayaensis (Saini et Vasu, 1997), comb. nov. A synoptic key is also provided for the known species of Oralia Malaise.
基金supported by the National Natural Science Foundation of China (31000967,31010103913)
文摘Based on comparison of the type specimens, Parapolytrechus [sic] flavotarsus Wang & Zheng, 2002 is a new junior synonym ofNeoxenicotela mausoni Breuning, 1947.
基金This study were supported by National Natural Science Foundation of China (3007009900)
文摘All Chinese species of the genus Milesia is revised in this paper. Six new synonyms were proposed, which are M. ruiliana Yang et Cheng and M. Tachina Yang et Cheng as synonyms of M. cretosa Hippa; M. maolana Cheng et Yang as synonym of M. ferruginosa Brunetti; M. atricorporis Yang et Cheng as synomym of M. quantula Hippa; M. vesparia Shiraki and M. turgidiverticis Yang et Cheng as synonyms of M. verticalis Brunetti. As far as we know, there are thirteen species distributing in China, among which, M. variegata Brunetti is recorded for the first time to China. An abdominal figure of each species is provided in this paper. Meanwhile, a key to all the Chinese species and a map of geographical distribution of these species are given.
文摘As a medium between two different languages, between peoples of two countries, translation is not only a matter of language, but also of cross-cultural transference. According to Professor He Ziran, socio-pragmatic translation is the kind of translation which examines the conditions on language use that stem from the social and cultural situations to serve cross-cultural communication. This paper focuses on the ways used to achieve socio-pragmatic equivalence in translation practice.
文摘Key Facts Synonyms:Sacrococcygeal teratoma(SGT),germ cell tumor of coccyx Definition:Tumors containing hair,teeth,cartilage,and fat extending from the coccyx and potentially growing both internally and externally.
文摘Nowadays,more and more university students have Teacher’s Book for College English. They know answers of exercises from it before they do them. Some of them just copy down the right answers and wait for teacher’s praise. In this situation, College English teachers should redesign the exercises after each unit so that students will be interested and involved in learning. This study thus suggests several ways to redesign the vocabulary exercises from “ College English". It expects, on the one hand, to raise College English teachers’ awareness of the necessity to change the exercises. On the other hand, it expects to give them an inspiration, and example of designing more appropriate exercises so as to reinforce students’ vocabulary and enhance their language awareness.
文摘Synonyms: Epidermoid tumor,non-neoplastic inclusion cyst, congenital cholesteatoma of the cerebellopontine angle cistern.Definition: Congenital lesion arising from inclusion of ectodermal epithelial elements at time of neural tube closure during 3rd to 5th week of embryonic life, resulting in migration abnormalities of epiblastic cells.Classic imaging appearance:(1)Signal shows an insinuating cisternal lesion with low T1, high T2 close to that of cerebrospinal fluid (CSF).(2)FLAIR shows incomplete or absent attenuation.(3)Diffusion-weighted imaging shows epidermoid cyst has restricted diffusion(high-signal lesion).Other key facts:(1)3rd most common cerebellopontine angle-internal auditory canal (CPA-IAC) mass.(2)1% of all intracranial tumors.
基金The work is supported by National Natural Science Foundation of China (No. 60121101).
文摘In this study, a comparative analysis of the codon usage bias was performed in Aeropyrum pernix K1 and two other phylogenetically related Crenarchaeota microorganisms (i.e., Pyrobaculum aerophilum str. IM2 and Sulfolobus acidocaldarius DSM 639). The results indicated that the synonymous codon usage in A. pernix K1 was less biased, which was highly correlated with the GC3s value. The codon usage patterns were phylogenetically conserved among these Crenarchaeota microorganisms. Comparatively, it is the species function rather than the gene function that determines their gene codon usage patterns. A. pernix K1, P. aerophilum str. IM2, and S. acidocaldarius DSM 639 live in differently extreme conditions. It is presumed that the hving environment played an important role in determining the codon usage pattern of these microorganisms. Besides, there was no strain-specific codon usage among these microorganisms. The extent of codon bias in A. pernix K1 and S. acidocaldarius DSM 639 were highly correlated with the gene expression level, but no such association was detected in P. aerophilum str. IM2 genomes.
基金supported by the Pilot Project of Standardized Curation,Data Integration and Resource Sharing of Zoological Collections (2005DKA21402)
文摘The genus Boeberia Prout,1901 from China is reviewed. A previously known species is redescribed: Boeberia parmenio(Bber,1809) and one species is synonymized: Boeberia polyommata Chou and Yuan,2001(=Satyrus ferula(Fabricius,1793)) . Illustrations of adults and male genitalia are provided.
基金supported by the National Natural Science Foundation of China (31401822)
文摘Apple(Malus×domestica) has been proposed as an important woody plant and the major cultivated fruit trees in temperate regions. Apple whole genome sequencing has been completed, which provided an excellent opportunity for genome-wide analysis of the synonymous codon usage patterns. In this study, a multivariate bioinformatics analysis was performed to reveal the characteristics of synonymous codon usage and the main factors affecting codon bias in apple. The neutrality, correspondence, and correlation analyses were performed by Codon W and SPSS(Statistical Product and Service Solutions) programs, indicating that the apple genome codon usage patterns were affected by mutational pressure and selective constraint. Meanwhile, coding sequence length and the hydrophobicity of proteins could also influence the codon usage patterns. In short, codon usage pattern analysis and determination of optimal codons has laid an important theoretical basis for genetic engineering, gene prediction and molecular evolution studies in apple.
文摘There is strong relationship between melanocortin-1 receptor (MCIR) gene variants and human hair color and skin type. Based on a sequencing study of MC1R gene in 50 individuals from the Uygur, Tibetan, Wa and Dai ethnic populations, we discuss the occurrence of 7 mc1r variants consisting of 5 nonsynonymous sites (Val60Leu, Arg67Gln, Val92Met, Arg163Gln and Ala299Val) and 2 synonymous sites (C414T and A942G), among which C414T and Ala299Val were reported for the first time. Confirmation and analysis were the made of 122 individuals at three common point mutations (Val92Met, Arg163Gln, A942G) using PCR-SSCP. The frequency of Arg163Gln variant varies in the four ethnic populations, with percentage of 40%, 85.0%, 66. 2% and 72.7%, respectively, while those of Val92Met and A942G are roughly similar in these four populations. The different environments, migration and admixture of various ethnic groups in China might have impact on the observed frequency of Arg163Gln.
文摘A comparative analysis of the codon usage bias was conducted in Methanosarcina mazei str. Goel and two related Euryarchaeota microorganisms (Picrophilus torridus str. DSM 9790 and Natronomonas pharaonis str. DSM 2160). Results revealed that synonymous codon usage in Methanosarcina mazei str. Goel was less biased, which was highly correlated with the GC3S value. And the codon usage patterns were phylogenetically conserved among those Euryarchaeota microorganisms. By employing a hierarchical clustering analysis, it can be seen that it is more the species than the gene function that determines their gene codon usage pattems. Considering that those microorganisms live in different environments where the pH conditions vary quite a lot, it can be presumed that their living environments, especially the pH conditions, play an important role in determining those microorganisms' codon usage pattems.
基金This project is supported by National Natural Science Foundation of China(No.61202439)partly supported by Scientific Research Foundation of Hunan Provincial Education Department of China(No.16A008)partly supported by Hunan Key Laboratory of Smart Roadway and Cooperative Vehicle-Infrastructure Systems(No.2017TP1016).
文摘For protecting the copyright of a text and recovering its original content harmlessly,this paper proposes a novel reversible natural language watermarking method that combines arithmetic coding and synonym substitution operations.By analyzing relative frequencies of synonymous words,synonyms employed for carrying payload are quantized into an unbalanced and redundant binary sequence.The quantized binary sequence is compressed by adaptive binary arithmetic coding losslessly to provide a spare for accommodating additional data.Then,the compressed data appended with the watermark are embedded into the cover text via synonym substitutions in an invertible manner.On the receiver side,the watermark and compressed data can be extracted by decoding the values of synonyms in the watermarked text,as a result of which the original context can be perfectly recovered by decompressing the extracted compressed data and substituting the replaced synonyms with their original synonyms.Experimental results demonstrate that the proposed method can extract the watermark successfully and achieve a lossless recovery of the original text.Additionally,it achieves a high embedding capacity.
基金Supported by Earmarked Fund for China Agriculture Research System(CARS-31-15)Construction of Plateau Discipline of Fujian Province(102/71201801101)
文摘[Objective] The objective of this study was to understand the codon usage bias pattern of banana pathogenesis-related 17 gene, Basic Secretory Protease gene(MaBSP). [Method] Relative codon usage patterns of MaBSP were calculated using the software CodonW version 1.4.2. and the web-based tool(http://kazusa.or.jp/codon/).[Result] Our findings showed that C-ended and G-ended codons were the most preferential except the TER codon UGA which was coded for by just one codon. The ENc value, relationship between AT bias and GC bias, Random synonymous codon usage(RSCU) and CAI all showed that codon bias usage existed in MaBSP gene.[Conclusion] The codon usage patterns of MaBSP gene is principally influenced by natural selection in the third position. However, other multiple factors also influence this pattern.
基金This work was supported by the Major State Basic Research Project(Grant No.G200007 7700)the National Natural Science Foundation of China(Grant Nos.40572006 and 40232020).
文摘With the verification of the type specimen by six experts from the Nanjing Institute of Geology and Palaeontology, the specimen of Xianfengella prima He and Yang, 1982 described by Qian (Qian, 2001, flge2: la-c) is confirmed to be the holotype specimen (NIGP. 84430) of Yangtzedonta primitiva Yu, 1985, and consequently, Yu Wen's view that they are not the same specimen is impractical. This fact demonstrates that Yangtzedonta primitiva Yu, 1985 is undoubtedly a junior synonym of Xianftngella prima He and Yang, 1982, and is invalid. Qian's conclusion (Qian, 2001 ) that no bivalve appeared in the early Meishucunian Stage of the Early Cambrian is rational.